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Search results 201 to 214 out of 214 for Zgrf1

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0.016s

Type

Details

Score

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Protein

Q0VGT4-2

Organism:	Mus musculus/domesticus
Length:	856
Fragment?:	false

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Protein

A0A0G2JGH8

Organism:	Mus musculus/domesticus
Length:	662
Fragment?:	true

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Publication

32640219 | -

First Author:	Brannvoll A
Year:	2020
Journal:	Cell Rep
Title:	The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells.
Volume:	32
Issue:	1
Pages:	107849

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Publication

15161972 | -

First Author:	Askree SH
Year:	2004
Journal:	Proc Natl Acad Sci U S A
Title:	A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length.
Volume:	101
Issue:	23
Pages:	8658-63

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Publication

26966246 | -

First Author:	Xue X
Year:	2016
Journal:	Genes Dev
Title:	Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1.
Volume:	30
Issue:	6
Pages:	687-99

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Publication

26966248 | -

First Author:	Silva S
Year:	2016
Journal:	Genes Dev
Title:	Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.
Volume:	30
Issue:	6
Pages:	700-17

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Protein Domain

IPR018838 | DUF2439

Type:

Domain

Description:

This domain can be found in proteins that have been implicated in telomere maintenance in Saccharomyces cerevisiae []and in meiotic chromosome segregation in Schizosaccharomyces pombe []. It can also be found in Mte1 (Mph1-associated telomere maintenance protein 1), human zinc finger protein ZGRF1 (C4ORF21) and fission yeast Dbl2 []. Mte1 is a D-loop-binding protein that interacts and stimulates the helicase and fork regression activities of Mph1 while inhibiting the ability of Mph1 to dissociate recombination intermediates. Mph1 and Mte1 interdependently colocalise at DNA damage-induced foci and dysfunctional telomeres. Mte1 is indicated to play a role in regulation of crossover recombination, response to replication stress, and telomere maintenance []. The fission yeast, Dbl2 is needed for cellular resistance to the topoisomerase I poison camptothecin, forms DNA damage-induced foci, and is needed for the optimal recruitment of Fml1 to DNA damage, while the human ZGRF1 protein has been linked to DNA cross-link repair and mutations of it have been found in a variety of human tumors []. ZGRF1 is a 5'-to-3'helicase that interacts with RAD51 and stimulates homologous recombination and, thus, promotes the repair of replication-blocking DNA lesions []. Having said that, there is no evidence to suggest that this domain is implicated in DNA damage resistance or for nuclear focus formation [].

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Publication

26920759 | -

First Author:	Yimit A
Year:	2016
Journal:	Genetics
Title:	MTE1 Functions with MPH1 in Double-Strand Break Repair.
Volume:	203
Issue:	1
Pages:	147-57

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Publication

16169489 | -

First Author:	Gregan J
Year:	2005
Journal:	Curr Biol
Title:	Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.
Volume:	15
Issue:	18
Pages:	1663-9

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Protein

I3PQW4

Organism:	Mus musculus/domesticus
Length:	1843
Fragment?:	false

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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