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Search results 201 to 273 out of 273 for Ano6

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:7450738
Assay Type: RNA in situ
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768124
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7451013
Age: embryonic day 16.5
Note: Expression is in mineralizing tissues of intramembranous bone.
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609813
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5469586
Age: embryonic day 8.5
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609813
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5469586
Age: embryonic day 8.5
Image: 1H
Specimen Label: 1H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1609817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5469586
Age: embryonic day 10.5
Image: 1M
Specimen Label: 1M
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5469627
Age: embryonic day 12.5
Image: 6H
Note: Expression was detected ubiquitously in all epithelial and mesenchymal cells of orofacial structures with more abundance in osteoblasts.
Specimen Label: 6H
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5469627
Age: embryonic day 14.5-15.0
Image: 6V
Note: Expression was ubiquitous in epithelia and mesenchyme of orofacial structures.
Specimen Label: 6V
Detected: true
Specimen Num: 30
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GXD Expression
GXD Expression
Probe: MGI:3821988
Assay Type: RNA in situ
Annotation Date: 2009-01-05
Strength: Weak
Sex: Female
Emaps: EMAPS:1796222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3822015
Age: embryonic day 14.5
Image: 3H
Note: Expression is in the epithelium and mesenchyme.
Specimen Label: 3H
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7451025
Age: embryonic day 14.5
Note: Expression is in the mineralizing areas of skeletal tissues.
Specimen Label: 2B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7450738
Assay Type: RNA in situ
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3724522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7451013
Age: embryonic day 14.5
Note: Expression is in mineralizing tissues of intramembranous bone.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5469627
Age: embryonic day 12.5
Image: 2M
Specimen Label: 2M
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3747121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5469627
Age: embryonic day 13.5
Image: 4H
Specimen Label: 4H
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3747121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5469627
Age: embryonic day 13.5
Image: 4C
Specimen Label: 4C
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:2255098
Assay Type: RNA in situ
Annotation Date: 2013-03-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3747122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5469627
Age: embryonic day 14.5
Image: 4M
Specimen Label: 4M
Detected: true
Specimen Num: 15
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Publication
27227820 | J:339035
First Author: Ishihara K
Year: 2016
Journal: Biochemistry
Title: Role of Ca(2+) in the Stability and Function of TMEM16F and 16K.
Volume: 55
Issue: 23
Pages: 3180-8
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Publication
31391337 | J:322924
 
First Author: Cabrita I
Year: 2019
Journal: JCI Insight
Title: Niclosamide repurposed for the treatment of inflammatory airway disease.
Volume: 4
Issue: 15
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Publication
24478309 | J:213003
First Author: Suzuki T
Year: 2014
Journal: J Biol Chem
Title: Functional swapping between transmembrane proteins TMEM16A and TMEM16F.
Volume: 289
Issue: 11
Pages: 7438-47
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Publication
23576756 | J:196141
First Author: Tien J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC).
Volume: 110
Issue: 16
Pages: 6352-7
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Publication
37989592 | J:346211
 
First Author: Xu Y
Year: 2024
Journal: J Neurosci
Title: Microglial Refinement of A-Fiber Projections in the Postnatal Spinal Cord Dorsal Horn Is Required for Normal Maturation of Dynamic Touch.
Volume: 44
Issue: 2
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Publication
27332874 | J:238366
First Author: Batti L
Year: 2016
Journal: Cell Rep
Title: TMEM16F Regulates Spinal Microglial Function in Neuropathic Pain States.
Volume: 15
Issue: 12
Pages: 2608-15
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Publication
23613533 | J:212784
First Author: Adomaviciene A
Year: 2013
Journal: J Physiol
Title: Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes.
Volume: 591
Issue: 14
Pages: 3487-505
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Publication
22075693 | J:190271
First Author: Duran C
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins.
Volume: 302
Issue: 3
Pages: C482-93
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Publication
35670667 | J:326252
   
First Author: Zhang Y
Year: 2022
Journal: Elife
Title: Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion.
Volume: 11
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Publication
26606969 | J:234129
First Author: Headland SE
Year: 2015
Journal: Sci Transl Med
Title: Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.
Volume: 7
Issue: 315
Pages: 315ra190
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Publication
18729231 | J:138798
First Author: Rock JR
Year: 2008
Journal: Dev Dyn
Title: Expression of TMEM16 paralogs during murine embryogenesis.
Volume: 237
Issue: 9
Pages: 2566-74
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Publication
19059364 | J:144232
First Author: Gritli-Linde A
Year: 2009
Journal: Gene Expr Patterns
Title: Expression patterns of the Tmem16 gene family during cephalic development in the mouse.
Volume: 9
Issue: 3
Pages: 178-91
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Publication
- | J:165963
     
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
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Publication
- | J:200814
     
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
21107324 | -
First Author: Suzuki J
Year: 2010
Journal: Nature
Title: Calcium-dependent phospholipid scrambling by TMEM16F.
Volume: 468
Issue: 7325
Pages: 834-8
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Publication
22006324 | -
First Author: Martins JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Anoctamin 6 is an essential component of the outwardly rectifying chloride channel.
Volume: 108
Issue: 44
Pages: 18168-72
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Protein Domain
IPR031295 | Anoctamin-6
Type: Family
Description: The anoctamin/TMEM16 family members include Ano1-10 (TMEM16A-J). They are membrane proteins involved in a variety of physiological functions, such as ion transport and ion channel regulation. TMEM16A and 16B are Ca(2+)-dependent Cl(-) channels; TMEM16C, 16D, 16F, 16G, and 16J have been classified as Ca(2+)-dependent lipid scramblases []. The anoctamin/TMEM16 family might have diverged in two or three different subclasses, channels, scramblases and dual-function channel/scramblases [].Anoctamin-6 (Ano6, TMEM16F) has calcium-dependent phospholipid scramblase activity []. Ano6 is a Ca(2+)-activated Cl(-) required for lipid scrambling in platelets during blood coagulation []and has an important role in chemokine-induced dendritic cell migration []. It is an essential component of the immune defense by macrophages []. Ano6 is a component of the outwardly rectifying chloride channel (ORCC) in airway epithelial cells and Jurkat T lymphocytes []. The Na(+)/Ca(2+) exchanger NCX1 requires Ano6 to efficiently translocate Ca(2+) out of osteoblasts into the calcifying bone matrix [].
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Protein
Q6P9J9
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Protein
A0A2I3BPX3
Organism: Mus musculus/domesticus
Length: 932  
Fragment?: false
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Protein
A0A2I3BPY8
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false
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Protein
A0A2I3BRD2
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Publication
28716969 | J:265642
First Author: Scoville DK
Year: 2017
Journal: FASEB J
Title: Genetic determinants of susceptibility to silver nanoparticle-induced acute lung inflammation in mice.
Volume: 31
Issue: 10
Pages: 4600-4611
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Publication
25451786 | -
First Author: Picollo A
Year: 2015
Journal: J Mol Biol
Title: TMEM16 proteins: unknown structure and confusing functions.
Volume: 427
Issue: 1
Pages: 94-105
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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