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Search results 1 to 55 out of 55 for Insig1

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Category: Publication
Type Details Score
Publication  
First Author: Azzu V
Year: 2021
Journal: Mol Metab
Title: Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression.
Volume: 48
Pages: 101210
Publication
First Author: McFarlane MR
Year: 2014
Journal: J Biol Chem
Title: Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine.
Volume: 289
Issue: 4
Pages: 2148-56
Publication
First Author: Bridges JP
Year: 2014
Journal: PLoS One
Title: Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation.
Volume: 9
Issue: 5
Pages: e91376
Publication
First Author: Carobbio S
Year: 2013
Journal: Diabetes
Title: Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity.
Volume: 62
Issue: 11
Pages: 3697-708
Publication
First Author: Nakagawa Y
Year: 2006
Journal: Nat Med
Title: TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
Volume: 12
Issue: 1
Pages: 107-13
Publication
First Author: Engelking LJ
Year: 2005
Journal: J Clin Invest
Title: Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Volume: 115
Issue: 9
Pages: 2489-98
Publication  
First Author: Tsushima H
Year: 2018
Journal: Development
Title: Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.
Volume: 145
Issue: 13
Publication
First Author: Li J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes.
Volume: 100
Issue: 16
Pages: 9476-81
Publication
First Author: Yabe D
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis.
Volume: 100
Issue: 6
Pages: 3155-60
Publication
First Author: Engelking LJ
Year: 2006
Journal: J Clin Invest
Title: Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.
Volume: 116
Issue: 9
Pages: 2356-65
Publication
First Author: Evers BM
Year: 2010
Journal: J Invest Dermatol
Title: Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.
Volume: 130
Issue: 5
Pages: 1237-48
Publication
First Author: Taghibiglou C
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide.
Volume: 413
Issue: 2
Pages: 159-63
Publication
First Author: Zhou ZS
Year: 2020
Journal: Nat Commun
Title: Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2.
Volume: 11
Issue: 1
Pages: 379
Publication  
First Author: Suzuki A
Year: 2019
Journal: Development
Title: Cholesterol metabolism plays a crucial role in the regulation of autophagy for cell differentiation of granular convoluted tubules in male mouse submandibular glands.
Volume: 146
Issue: 20
Publication
First Author: Tsai YC
Year: 2012
Journal: Mol Biol Cell
Title: Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
Volume: 23
Issue: 23
Pages: 4484-94
Publication
First Author: Yabe D
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.
Volume: 99
Issue: 20
Pages: 12753-8
Publication
First Author: Vergnes L
Year: 2016
Journal: J Lipid Res
Title: SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.
Volume: 57
Issue: 3
Pages: 410-21
Publication
First Author: Patra D
Year: 2014
Journal: PLoS One
Title: Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.
Volume: 9
Issue: 8
Pages: e105674
Publication
First Author: Wong BH
Year: 2016
Journal: J Biol Chem
Title: Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.
Volume: 291
Issue: 20
Pages: 10501-14
Publication  
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
Publication
First Author: Pfister S
Year: 2011
Journal: Int J Dev Biol
Title: Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.
Volume: 55
Issue: 1
Pages: 45-58
Publication
First Author: Ansarullah
Year: 2021
Journal: Nature
Title: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
Volume: 590
Issue: 7845
Pages: 326-331
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Peng Y
Year: 1997
Journal: Genomics
Title: Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene.
Volume: 43
Issue: 3
Pages: 278-84
Publication  
First Author: Crewe C
Year: 2019
Journal: JCI Insight
Title: SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1.
Volume: 5
Issue: 15
Publication
First Author: Kim C
Year: 2016
Journal: Biochim Biophys Acta
Title: RNA-binding protein HuD reduces triglyceride production in pancreatic β cells by enhancing the expression of insulin-induced gene 1.
Volume: 1859
Issue: 4
Pages: 675-85
Publication  
First Author: Helmering J
Year: 2014
Journal: Lipids Health Dis
Title: A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice.
Volume: 13
Pages: 167
Publication
First Author: Xu JL
Year: 2018
Journal: J Lipid Res
Title: Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice.
Volume: 59
Issue: 1
Pages: 35-47
Publication
First Author: Xu D
Year: 2020
Journal: Nature
Title: The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Volume: 580
Issue: 7804
Pages: 530-535