REPIN1, also known as the replication initiation-region protein 60kDa (RIP60), is a zinc finger protein involved in DNA binding and bending during initiation of DNA replication. It is highly expressed in liver and adipose tissue and may have a role in adipocyte function []. The genetic variation in human REPIN1 has been shown to play a role in glucose and lipid metabolism by differentially affecting the expression of REPIN1 target genes including glucose and fatty acid transporters [].
