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Search results 1 to 100 out of 305 for Lrrk2

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Category: Publication
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Type Details Score
Publication
29760073 | J:263561
First Author: Kim KS
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease.
Volume: 115
Issue: 22
Pages: E5164-E5173
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Publication
18445495 | J:201943
First Author: Shin N
Year: 2008
Journal: Exp Cell Res
Title: LRRK2 regulates synaptic vesicle endocytosis.
Volume: 314
Issue: 10
Pages: 2055-65
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Publication
27364102 | J:260952
 
First Author: Bang Y
Year: 2016
Journal: Mol Cell Neurosci
Title: LRRK2 interferes with aggresome formation for autophagic clearance.
Volume: 75
Pages: 71-80
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Publication
23936174 | J:204940
First Author: Bichler Z
Year: 2013
Journal: PLoS One
Title: Non-motor and motor features in LRRK2 transgenic mice.
Volume: 8
Issue: 7
Pages: e70249
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Publication
23886663 | J:203137
First Author: Fraser KB
Year: 2013
Journal: Hum Mol Genet
Title: LRRK2 secretion in exosomes is regulated by 14-3-3.
Volume: 22
Issue: 24
Pages: 4988-5000
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Publication
22302802 | J:181348
First Author: Moehle MS
Year: 2012
Journal: J Neurosci
Title: LRRK2 inhibition attenuates microglial inflammatory responses.
Volume: 32
Issue: 5
Pages: 1602-11
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Publication
16980962 | J:113152
First Author: Smith WW
Year: 2006
Journal: Nat Neurosci
Title: Kinase activity of mutant LRRK2 mediates neuronal toxicity.
Volume: 9
Issue: 10
Pages: 1231-3
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Publication
20850369 | J:172418
First Author: Dächsel JC
Year: 2010
Journal: Parkinsonism Relat Disord
Title: A comparative study of Lrrk2 function in primary neuronal cultures.
Volume: 16
Issue: 10
Pages: 650-5
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Publication
27539321 | J:238938
First Author: Ferrazza R
Year: 2016
Journal: Biochem Biophys Res Commun
Title: LRRK2 deficiency impacts ceramide metabolism in brain.
Volume: 478
Issue: 3
Pages: 1141-6
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Publication
21168496 | J:170730
First Author: Winner B
Year: 2011
Journal: Neurobiol Dis
Title: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice.
Volume: 41
Issue: 3
Pages: 706-16
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Publication
26546614 | J:227621
First Author: Lavalley NJ
Year: 2016
Journal: Hum Mol Genet
Title: 14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening.
Volume: 25
Issue: 1
Pages: 109-22
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Publication
28821568 | J:246273
First Author: Liu W
Year: 2017
Journal: J Exp Med
Title: LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection.
Volume: 214
Issue: 10
Pages: 3051-3066
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Publication
33006315 | J:298675
   
First Author: Chen C
Year: 2020
Journal: Elife
Title: Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations.
Volume: 9
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Publication
25309331 | J:242269
 
First Author: Beccano-Kelly DA
Year: 2014
Journal: Front Cell Neurosci
Title: Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice.
Volume: 8
Pages: 301
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Publication
25926623 | J:223805
First Author: Moehle MS
Year: 2015
Journal: Hum Mol Genet
Title: The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.
Volume: 24
Issue: 15
Pages: 4250-67
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Publication
- | J:170000
     
First Author: Ouyang Y
Year: 2011
Journal: MGI Direct Data Submission
Title: Generation of a new Lrrk2 knockout allele
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Publication
30150626 | J:266239
First Author: Bae EJ
Year: 2018
Journal: Nat Commun
Title: LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
Volume: 9
Issue: 1
Pages: 3465
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Publication
29855356 | J:268923
First Author: Henderson MX
Year: 2018
Journal: Acta Neuropathol Commun
Title: LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons.
Volume: 6
Issue: 1
Pages: 45
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Publication
34759048 | J:317441
 
First Author: Kim JW
Year: 2021
Journal: eNeuro
Title: Dysregulated mRNA Translation in the G2019S LRRK2 and LRRK2 Knock-Out Mouse Brains.
Volume: 8
Issue: 6
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Publication
26365310 | J:227005
 
First Author: Choi I
Year: 2015
Journal: Nat Commun
Title: LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase.
Volume: 6
Pages: 8255
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Publication
25343991 | J:219227
First Author: Beccano-Kelly DA
Year: 2015
Journal: Hum Mol Genet
Title: LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory.
Volume: 24
Issue: 5
Pages: 1336-49
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Publication
22080837 | J:180209
First Author: Kett LR
Year: 2012
Journal: Hum Mol Genet
Title: LRRK2 Parkinson disease mutations enhance its microtubule association.
Volume: 21
Issue: 4
Pages: 890-9
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Publication
25501810 | J:263463
First Author: Arranz AM
Year: 2015
Journal: J Cell Sci
Title: LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism.
Volume: 128
Issue: 3
Pages: 541–52
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Publication
30927072 | J:294451
First Author: Bieri G
Year: 2019
Journal: Acta Neuropathol
Title: LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Volume: 137
Issue: 6
Pages: 961-980
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Publication
22539006 | J:204793
First Author: Chen CY
Year: 2012
Journal: Cell Death Differ
Title: (G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD.
Volume: 19
Issue: 10
Pages: 1623-33
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Publication
28720718 | J:259183
 
First Author: Chen ZC
Year: 2017
Journal: Sci Signal
Title: Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.
Volume: 10
Issue: 488
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23646112 | J:200871
First Author: Sepulveda B
Year: 2013
Journal: PLoS One
Title: Short- and long-term effects of LRRK2 on axon and dendrite growth.
Volume: 8
Issue: 4
Pages: e61986
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33483550 | J:300371
First Author: Lebovitz C
Year: 2021
Journal: Sci Rep
Title: Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis.
Volume: 11
Issue: 1
Pages: 2097
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Publication
29408508 | J:272990
First Author: Chen J
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Role of LRRK2 in manganese-induced neuroinflammation and microglial autophagy.
Volume: 498
Issue: 1
Pages: 171-177
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Publication
30048714 | J:268603
 
First Author: Kelly K
Year: 2018
Journal: Exp Neurol
Title: The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition.
Volume: 309
Pages: 1-13
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Publication
23675505 | J:200623
First Author: Giesert F
Year: 2013
Journal: PLoS One
Title: Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.
Volume: 8
Issue: 5
Pages: e63778
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Publication
29875204 | J:262329
 
First Author: Takagawa T
Year: 2018
Journal: Sci Transl Med
Title: An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis.
Volume: 10
Issue: 444
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Publication
22850484 | J:197505
First Author: Mandemakers W
Year: 2012
Journal: Neurobiol Dis
Title: LRRK2 expression is enriched in the striosomal compartment of mouse striatum.
Volume: 48
Issue: 3
Pages: 582-93
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Publication
24282027 | J:204661
First Author: Stafa K
Year: 2014
Journal: Hum Mol Genet
Title: Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.
Volume: 23
Issue: 8
Pages: 2055-77
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Publication
24464040 | J:206832
First Author: Parisiadou L
Year: 2014
Journal: Nat Neurosci
Title: LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity.
Volume: 17
Issue: 3
Pages: 367-76
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Publication
18790059 | J:142519
First Author: Westerlund M
Year: 2008
Journal: Mol Cell Neurosci
Title: Lrrk2 and alpha-synuclein are co-regulated in rodent striatum.
Volume: 39
Issue: 4
Pages: 586-91
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Publication
29541021 | J:277870
 
First Author: Perez Carrion M
Year: 2018
Journal: Front Mol Neurosci
Title: The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1.
Volume: 11
Pages: 64
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18045479 | J:143967
 
First Author: Biskup S
Year: 2007
Journal: BMC Neurosci
Title: Dynamic and redundant regulation of LRRK2 and LRRK1 expression.
Volume: 8
Pages: 102
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34658337 | J:312767
   
First Author: Khan SS
Year: 2021
Journal: Elife
Title: Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain.
Volume: 10
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Publication
29088368 | J:256289
First Author: Nguyen APT
Year: 2018
Journal: Hum Mol Genet
Title: G2019S LRRK2 enhances the neuronal transmission of tau in the mouse brain.
Volume: 27
Issue: 1
Pages: 120-134
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19890007 | J:154755
First Author: Parisiadou L
Year: 2009
Journal: J Neurosci
Title: Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.
Volume: 29
Issue: 44
Pages: 13971-80
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Publication
28582422 | J:246676
First Author: Rassu M
Year: 2017
Journal: PLoS One
Title: Role of LRRK2 in the regulation of dopamine receptor trafficking.
Volume: 12
Issue: 6
Pages: e0179082
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Publication
23949442 | J:206851
 
First Author: Yun HJ
Year: 2013
Journal: Exp Mol Med
Title: LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.
Volume: 45
Pages: e36
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Publication
29305532 | J:259435
First Author: Lim J
Year: 2018
Journal: J Neurosci
Title: LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT1A Receptor Upregulation in Mice.
Volume: 38
Issue: 7
Pages: 1611-1621
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24427314 | J:211935
First Author: Dorval V
Year: 2014
Journal: PLoS One
Title: Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models.
Volume: 9
Issue: 1
Pages: e85510
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Publication
24633735 | J:248612
First Author: West AB
Year: 2014
Journal: J Comp Neurol
Title: Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents.
Volume: 522
Issue: 11
Pages: 2465-80
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Publication
29054882 | J:251142
First Author: Pan PY
Year: 2017
Journal: J Neurosci
Title: Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.
Volume: 37
Issue: 47
Pages: 11366-11376
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Publication
19667187 | J:151944
First Author: Tong Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.
Volume: 106
Issue: 34
Pages: 14622-7
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Publication
28576705 | J:268730
 
First Author: Giesert F
Year: 2017
Journal: Neurobiol Dis
Title: The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse.
Volume: 105
Pages: 179-193
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Publication
23241745 | J:194408
First Author: Sheng Z
Year: 2012
Journal: Sci Transl Med
Title: Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations.
Volume: 4
Issue: 164
Pages: 164ra161
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Publication
29789389 | J:265330
 
First Author: Härtlova A
Year: 2018
Journal: EMBO J
Title: LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.
Volume: 37
Issue: 12
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26824392 | J:230329
   
First Author: Steger M
Year: 2016
Journal: Elife
Title: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
Volume: 5
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Publication
37633049 | J:341116
 
First Author: Zhang S
Year: 2023
Journal: Redox Biol
Title: LRRK2 aggravates kidney injury through promoting MFN2 degradation and abnormal mitochondrial integrity.
Volume: 66
Pages: 102860
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37640963 | J:339869
     
First Author: Lian H
Year: 2023
Journal: Nat Microbiol
Title: Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella.
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20130188 | J:157931
First Author: Li X
Year: 2010
Journal: J Neurosci
Title: Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S.
Volume: 30
Issue: 5
Pages: 1788-97
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23395371 | J:233567
First Author: MacLeod DA
Year: 2013
Journal: Neuron
Title: RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.
Volume: 77
Issue: 3
Pages: 425-39
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26251043 | J:226183
First Author: Henry AG
Year: 2015
Journal: Hum Mol Genet
Title: Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression.
Volume: 24
Issue: 21
Pages: 6013-28
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17120249 | J:210913
First Author: Biskup S
Year: 2006
Journal: Ann Neurol
Title: Localization of LRRK2 to membranous and vesicular structures in mammalian brain.
Volume: 60
Issue: 5
Pages: 557-69
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Publication
- | J:314235
     
First Author: Mazza MC
Year: 2020
Journal: bioRxiv
Title: Combined knockout of Lrrk2 and Rab29 does not result in behavioral abnormalities in vivo
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34340748 | J:313755
   
First Author: Singh F
Year: 2021
Journal: Elife
Title: Pharmacological rescue of impaired mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in mice.
Volume: 10
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25836420 | J:223350
 
First Author: Yue M
Year: 2015
Journal: Neurobiol Dis
Title: Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Volume: 78
Pages: 172-95
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20016100 | J:157100
First Author: Andres-Mateos E
Year: 2009
Journal: J Neurosci
Title: Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).
Volume: 29
Issue: 50
Pages: 15846-50
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34831434 | J:315027
 
First Author: Maset A
Year: 2021
Journal: Cells
Title: Aberrant Patterns of Sensory-Evoked Activity in the Olfactory Bulb of LRRK2 Knockout Mice.
Volume: 10
Issue: 11
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30194047 | J:268723
 
First Author: Zhao Y
Year: 2018
Journal: Neurobiol Dis
Title: Nigrostriatal pathology with reduced astrocytes in LRRK2 S910/S935 phosphorylation deficient knockin mice.
Volume: 120
Pages: 76-87
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23270607 | J:206546
 
First Author: Paus M
Year: 2013
Journal: Brain Res
Title: Enhanced dendritogenesis and axogenesis in hippocampal neuroblasts of LRRK2 knockout mice.
Volume: 1497
Pages: 85-100
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29800472 | J:319286
First Author: Kozina E
Year: 2018
Journal: Brain
Title: Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo.
Volume: 141
Issue: 6
Pages: 1753-1769
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32057291 | J:287322
   
First Author: Weindel CG
Year: 2020
Journal: Elife
Title: LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis.
Volume: 9
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24682598 | J:213425
First Author: Schapansky J
Year: 2014
Journal: Hum Mol Genet
Title: Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy.
Volume: 23
Issue: 16
Pages: 4201-14
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32853409 | J:315649
First Author: Liu Z
Year: 2020
Journal: EMBO J
Title: LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.
Volume: 39
Issue: 20
Pages: e104862
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33135724 | J:300328
First Author: Kalogeropulou AF
Year: 2020
Journal: Biochem J
Title: Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.
Volume: 477
Issue: 22
Pages: 4397-4423
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26363496 | J:229559
 
First Author: Weng YH
Year: 2016
Journal: Exp Neurol
Title: (R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model.
Volume: 275 Pt 1
Pages: 104-15
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29038245 | J:251390
First Author: Verma M
Year: 2017
Journal: J Neurosci
Title: Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants.
Volume: 37
Issue: 46
Pages: 11151-11165
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21307259 | J:169453
First Author: Piccoli G
Year: 2011
Journal: J Neurosci
Title: LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.
Volume: 31
Issue: 6
Pages: 2225-37
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29917075 | J:266878
First Author: Pellegrini L
Year: 2018
Journal: Hum Mol Genet
Title: Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.
Volume: 27
Issue: 18
Pages: 3257-3271
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34446559 | J:309568
 
First Author: Tian Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: LRRK2 plays essential roles in maintaining lung homeostasis and preventing the development of pulmonary fibrosis.
Volume: 118
Issue: 35
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37487100 | J:339292
First Author: Yadavalli N
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition.
Volume: 120
Issue: 31
Pages: e2303789120
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23231918 | J:193185
First Author: Cherra SJ 3rd
Year: 2013
Journal: Am J Pathol
Title: Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons.
Volume: 182
Issue: 2
Pages: 474-84
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26811536 | J:237645
First Author: Langston RG
Year: 2016
Journal: Biochem J
Title: The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.
Volume: 473
Issue: 3
Pages: 221-32
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26355680 | J:278475
First Author: Imai Y
Year: 2015
Journal: PLoS Genet
Title: The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.
Volume: 11
Issue: 9
Pages: e1005503
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27273569 | J:239897
 
First Author: Nucifora FC Jr
Year: 2016
Journal: Nat Commun
Title: Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.
Volume: 7
Pages: 11792
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24733019 | J:215217
First Author: Sanchez G
Year: 2014
Journal: PLoS One
Title: Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice.
Volume: 9
Issue: 4
Pages: e94826
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22615783 | J:187237
First Author: Herzig MC
Year: 2012
Journal: PLoS One
Title: High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain.
Volume: 7
Issue: 5
Pages: e36581
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Publication
33523017 | J:333458
First Author: Mazza MC
Year: 2021
Journal: J Parkinsons Dis
Title: Combined Knockout of Lrrk2 and Rab29 Does Not Result in Behavioral Abnormalities in vivo.
Volume: 11
Issue: 2
Pages: 569-584
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37874635 | J:344182
   
First Author: Dhekne HS
Year: 2023
Journal: Elife
Title: Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson's disease-linked LRRK2 kinase.
Volume: 12
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Publication
32434048 | J:298377
 
First Author: Heaton GR
Year: 2020
Journal: Neurobiol Dis
Title: Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
Volume: 141
Pages: 104948
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Publication
28098219 | J:271727
 
First Author: Liu HF
Year: 2017
Journal: Sci Rep
Title: Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson's disease.
Volume: 7
Pages: 40887
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Publication
36055602 | J:329339
 
First Author: Liu Y
Year: 2022
Journal: Free Radic Biol Med
Title: LRRK2 deficiency protects the heart against myocardial infarction injury in mice via the P53/HMGB1 pathway.
Volume: 191
Pages: 119-127
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Publication
30890692 | J:290752
First Author: Ludtmann MHR
Year: 2019
Journal: Cell Death Dis
Title: LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation.
Volume: 10
Issue: 4
Pages: 265
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Publication
29386392 | J:259856
First Author: Xiong Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.
Volume: 115
Issue: 7
Pages: 1635-1640
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Publication
34077533 | J:321364
First Author: Araki M
Year: 2021
Journal: Hum Mol Genet
Title: BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice.
Volume: 30
Issue: 17
Pages: 1618-1631
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Publication
25356398 | J:274953
First Author: Liu HF
Year: 2014
Journal: Ann Clin Transl Neurol
Title: LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity.
Volume: 1
Issue: 3
Pages: 199-208
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Publication
23937259 | J:203862
First Author: Lobbestael E
Year: 2013
Journal: Biochem J
Title: Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle.
Volume: 456
Issue: 1
Pages: 119-28
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Publication
22363216 | J:183409
First Author: Stafa K
Year: 2012
Journal: PLoS Genet
Title: GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1.
Volume: 8
Issue: 2
Pages: e1002526
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Publication
30670047 | J:295145
First Author: Zhang M
Year: 2019
Journal: J Transl Med
Title: LRRK2 is involved in the pathogenesis of system lupus erythematosus through promoting pathogenic antibody production.
Volume: 17
Issue: 1
Pages: 37
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Publication
27378696 | J:237862
First Author: Ma B
Year: 2016
Journal: Hum Mol Genet
Title: LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1 -mediated signalling pathways.
Volume: 25
Issue: 16
Pages: 3515-3523
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Publication
32631998 | J:294731
First Author: Nguyen APT
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
Volume: 117
Issue: 29
Pages: 17296-17307
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Publication
29246723 | J:268285
 
First Author: Schapansky J
Year: 2018
Journal: Neurobiol Dis
Title: Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
Volume: 111
Pages: 26-35
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Publication
22899650 | J:188340
First Author: Berwick DC
Year: 2012
Journal: Hum Mol Genet
Title: LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.
Volume: 21
Issue: 22
Pages: 4966-79
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Publication
23082216 | J:192197
First Author: Trancikova A
Year: 2012
Journal: PLoS One
Title: Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations.
Volume: 7
Issue: 10
Pages: e47784
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Publication
28103901 | J:337385
First Author: Berwick DC
Year: 2017
Journal: Mol Neurodegener
Title: Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling.
Volume: 12
Issue: 1
Pages: 9
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