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Search results 101 to 200 out of 295 for Rap1a

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Hits by Pathway

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7464606
Assay Type: RT-PCR
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Stage: TS27
Assay Id: MGI:7464640
Age: postnatal day 2
Image: 1
Specimen Label: P2
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:7464628
Assay Type: Western blot
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:7464644
Age: embryonic day 17.5
Image: 2
Specimen Label: WT1
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464628
Assay Type: Western blot
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:7464644
Age: embryonic day 17.5
Image: 2
Specimen Label: WT2
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464628
Assay Type: Western blot
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:7464644
Age: embryonic day 17.5
Image: 2
Specimen Label: WT3
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464628
Assay Type: Western blot
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:7464644
Age: embryonic day 17.5
Image: 2
Specimen Label: cKO1
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:7464628
Assay Type: Western blot
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:7464644
Age: embryonic day 17.5
Image: 2
Specimen Label: cKO2
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:7464628
Assay Type: Western blot
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:7464644
Age: embryonic day 17.5
Image: 2
Specimen Label: cKO3
Detected: true
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679917
Pattern: Widespread
Stage: TS17
Assay Id: MGI:7464642
Age: embryonic day 10.5
Image: 1E E10.5
Specimen Label: 1E E10.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7464646
Age: embryonic day 17.5
Image: 2C E17.5 WT
Specimen Label: 2C E17.5 WT
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7464646
Age: embryonic day 17.5
Image: 2C E17.5 cKO
Note: Reduced expression compared with the control.
Specimen Label: 2C E17.5 cKO
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464642
Age: postnatal day 21
Image: 1E P21
Note: Mostly membrane associated.
Specimen Label: 1E P21
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7464646
Age: embryonic day 11.5
Image: 2C E11.5 WT
Specimen Label: 2C E11.5 WT
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7464646
Age: embryonic day 11.5
Image: 2C E11.5 cKO
Note: Reduced expression compared with the control.
Specimen Label: 2C E11.5 cKO
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4429594
Age: embryonic day 12.5
Specimen Label: 1D-/-
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7464646
Age: embryonic day 17.5
Image: 2C E17.5 WT
Specimen Label: 2C E17.5 WT
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7464646
Age: embryonic day 17.5
Image: 2C E17.5 cKO
Note: Reduced expression compared with the control.
Specimen Label: 2C E17.5 cKO
Detected: true
Specimen Num: 4
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•
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•
GXD Expression
GXD Expression
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464642
Age: postnatal day 21
Image: 1E P21
Note: Mostly membrane associated.
Specimen Label: 1E P21
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7464646
Age: embryonic day 11.5
Image: 2C E11.5 WT
Specimen Label: 2C E11.5 WT
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464628
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7464646
Age: embryonic day 11.5
Image: 2C E11.5 cKO
Note: Reduced expression compared with the control.
Specimen Label: 2C E11.5 cKO
Detected: true
Specimen Num: 2
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Publication
30442677 | J:269782
First Author: Bromberger T
Year: 2018
Journal: Blood
Title: Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice.
Volume: 132
Issue: 26
Pages: 2754-2762
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Publication
26804993 | J:259656
First Author: Nagai T
Year: 2016
Journal: Neuron
Title: Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Volume: 89
Issue: 3
Pages: 550-65
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Publication
18056342 | J:155204
First Author: Morton AM
Year: 2007
Journal: J Immunol
Title: Inverse Rap1 and phospho-ERK expression discriminate the maintenance phase of tolerance and priming of antigen-specific CD4+ T cells in vitro and in vivo.
Volume: 179
Issue: 12
Pages: 8026-34
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Publication
15870282 | J:98884
First Author: Dillon TJ
Year: 2005
Journal: Mol Cell Biol
Title: Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4.
Volume: 25
Issue: 10
Pages: 4117-28
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Publication
25807985 | J:222867
First Author: Lakshmikanthan S
Year: 2015
Journal: EMBO Rep
Title: Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.
Volume: 16
Issue: 5
Pages: 628-37
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Publication
30307978 | J:268405
First Author: Ferrara-Romeo I
Year: 2018
Journal: PLoS One
Title: Mice lacking RAP1 show early onset and higher rates of DEN-induced hepatocellular carcinomas in female mice.
Volume: 13
Issue: 10
Pages: e0204909
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Publication
34140948 | J:315042
 
First Author: Ishihara S
Year: 2021
Journal: Front Immunol
Title: Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.
Volume: 12
Pages: 624419
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Publication
31403469 | J:292633
First Author: Kaneko K
Year: 2019
Journal: J Clin Invest
Title: Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition.
Volume: 129
Issue: 9
Pages: 3786-3791
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Publication
29277598 | J:257125
 
First Author: Wong KHK
Year: 2018
Journal: J Mol Cell Cardiol
Title: Deletion of Rap1 disrupts redox balance and impairs endothelium-dependent relaxations.
Volume: 115
Pages: 1-9
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Publication
22732430 | J:203595
First Author: Sadrian B
Year: 2012
Journal: Mol Cell Neurosci
Title: Rap1gap2 regulates axon outgrowth in olfactory sensory neurons.
Volume: 50
Issue: 3-4
Pages: 272-82
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Publication
9330640 | J:43460
First Author: Wani MA
Year: 1997
Journal: Somat Cell Mol Genet
Title: Expression of Rap 1 suppresses genomic instability of H-ras transformed mouse fibroblasts.
Volume: 23
Issue: 2
Pages: 123-33
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Publication
18191594 | J:131149
First Author: Lin KB
Year: 2008
Journal: Immunity
Title: The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.
Volume: 28
Issue: 1
Pages: 75-87
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Publication
19965628 | J:156834
First Author: Ebisuno Y
Year: 2010
Journal: Blood
Title: Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in RAPL-dependent and -independent manners.
Volume: 115
Issue: 4
Pages: 804-14
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Publication
30360518 | J:314551
 
First Author: Ke CC
Year: 2018
Journal: Int J Mol Sci
Title: TBC1D21 Potentially Interacts with and Regulates Rap1 during Murine Spermatogenesis.
Volume: 19
Issue: 11
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Publication
8781548 | J:35064
First Author: Kondoh N
Year: 1996
Journal: Biochim Biophys Acta
Title: The S29 ribosomal protein increases tumor suppressor activity of K rev-1 gene on v-K ras-transformed NIH3T3 cells.
Volume: 1313
Issue: 1
Pages: 41-6
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Publication
19567880 | J:152246
First Author: Katayama Y
Year: 2009
Journal: Blood
Title: Rap signaling is crucial for the competence of IL-7 response and the development of B-lineage cells.
Volume: 114
Issue: 9
Pages: 1768-75
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Publication
20824186 | J:165021
 
First Author: Königsberger S
Year: 2010
Journal: PLoS One
Title: HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion.
Volume: 5
Issue: 9
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Publication
20127719 | J:161246
First Author: Milani R
Year: 2010
Journal: J Cell Biochem
Title: Phosphoproteome reveals an atlas of protein signaling networks during osteoblast adhesion.
Volume: 109
Issue: 5
Pages: 957-66
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Publication
15894621 | J:99817
First Author: Regier DS
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling.
Volume: 102
Issue: 21
Pages: 7595-600
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Publication
30242097 | J:322715
First Author: Lagarrigue F
Year: 2018
Journal: Blood Adv
Title: Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.
Volume: 2
Issue: 18
Pages: 2358-2368
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Publication
24803656 | J:213588
First Author: Le Borgne M
Year: 2014
Journal: Development
Title: The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway.
Volume: 141
Issue: 10
Pages: 2096-107
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Publication
26634692 | J:228314
 
First Author: Ishihara S
Year: 2015
Journal: Nat Commun
Title: Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis.
Volume: 6
Pages: 8982
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Publication
27707879 | J:237632
First Author: Ni J
Year: 2016
Journal: J Biol Chem
Title: MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes.
Volume: 291
Issue: 47
Pages: 24406-24417
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Publication
28213494 | J:241589
First Author: Strazza M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PLCε1 regulates SDF-1α-induced lymphocyte adhesion and migration to sites of inflammation.
Volume: 114
Issue: 10
Pages: 2693-2698
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Publication
33974562 | J:322269
 
First Author: Kaneko K
Year: 2021
Journal: JCI Insight
Title: Rap1 in the VMH regulates glucose homeostasis.
Volume: 6
Issue: 11
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Publication
30353093 | J:323748
First Author: Wang N
Year: 2018
Journal: Sci Rep
Title: The Sema3A receptor Plexin-A1 suppresses supernumerary axons through Rap1 GTPases.
Volume: 8
Issue: 1
Pages: 15647
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Publication
32539601 | J:319338
First Author: Perdomo L
Year: 2020
Journal: Circ Res
Title: Large Extracellular Vesicle-Associated Rap1 Accumulates in Atherosclerotic Plaques, Correlates With Vascular Risks and Is Involved in Atherosclerosis.
Volume: 127
Issue: 6
Pages: 747-760
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Publication
23616533 | J:196950
First Author: Subramanian J
Year: 2013
Journal: J Neurosci
Title: Rap1 signaling prevents L-type calcium channel-dependent neurotransmitter release.
Volume: 33
Issue: 17
Pages: 7245-52
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Publication
17254020 | J:122538
First Author: Obara Y
Year: 2007
Journal: J Neurochem
Title: The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells.
Volume: 101
Issue: 2
Pages: 470-82
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Publication
18180377 | J:131580
First Author: Wang SF
Year: 2008
Journal: Blood
Title: Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling.
Volume: 111
Issue: 5
Pages: 2878-86
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Publication
18577515 | J:140367
First Author: Sabbatini ME
Year: 2008
Journal: J Biol Chem
Title: Rap1 activation plays a regulatory role in pancreatic amylase secretion.
Volume: 283
Issue: 35
Pages: 23884-94
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Publication
18422604 | J:141709
First Author: Takahashi M
Year: 2008
Journal: Genes Cells
Title: Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.
Volume: 13
Issue: 6
Pages: 549-69
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Publication
18937323 | J:145583
First Author: Aivatiadou E
Year: 2009
Journal: Mol Reprod Dev
Title: cAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector.
Volume: 76
Issue: 4
Pages: 407-16
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Publication
21516100 | J:173935
First Author: Jossin Y
Year: 2011
Journal: Nat Neurosci
Title: Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex.
Volume: 14
Issue: 6
Pages: 697-703
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Publication
18596699 | J:137819
First Author: Stieglitz B
Year: 2008
Journal: EMBO J
Title: Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II.
Volume: 27
Issue: 14
Pages: 1995-2005
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Publication
17403904 | J:122332
First Author: Ménasché G
Year: 2007
Journal: Mol Cell Biol
Title: RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation.
Volume: 27
Issue: 11
Pages: 4070-81
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Publication
26921307 | J:256602
First Author: Ueda Y
Year: 2016
Journal: J Immunol
Title: Sema3e/Plexin D1 Modulates Immunological Synapse and Migration of Thymocytes by Rap1 Inhibition.
Volume: 196
Issue: 7
Pages: 3019-31
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Publication
25780038 | J:311957
First Author: Ring S
Year: 2015
Journal: J Immunol
Title: Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway.
Volume: 194
Issue: 8
Pages: 3735-44
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Publication
11937300 | J:76108
First Author: Mathews CE
Year: 2002
Journal: Free Radic Biol Med
Title: Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice.
Volume: 32
Issue: 8
Pages: 744-51
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Publication
26844834 | J:253271
First Author: Cahill ME
Year: 2016
Journal: Neuron
Title: Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling.
Volume: 89
Issue: 3
Pages: 566-82
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Publication
32158758 | J:292548
 
First Author: Burr SD
Year: 2020
Journal: Front Cell Dev Biol
Title: The Impact of Diabetic Conditions and AGE/RAGE Signaling on Cardiac Fibroblast Migration.
Volume: 8
Pages: 112
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Publication
19887591 | J:154765
First Author: Miyata M
Year: 2009
Journal: J Cell Sci
Title: Localization of nectin-free afadin at the leading edge and its involvement in directional cell movement induced by platelet-derived growth factor.
Volume: 122
Issue: Pt 23
Pages: 4319-29
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Publication
19635461 | J:152727
First Author: Kanemura H
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.
Volume: 387
Issue: 4
Pages: 754-9
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Publication
23886837 | J:203698
First Author: Wilson CW
Year: 2013
Journal: Blood
Title: Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.
Volume: 122
Issue: 22
Pages: 3678-90
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Publication
35197328 | J:322712
First Author: Lagarrigue F
Year: 2022
Journal: J Immunol
Title: Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4+ T Cells.
Volume: 208
Issue: 6
Pages: 1378-1388
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Publication
37598341 | J:341186
First Author: Sun H
Year: 2023
Journal: Cell Rep
Title: IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function.
Volume: 42
Issue: 8
Pages: 112996
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Publication
33104169 | J:310835
 
First Author: Sun H
Year: 2021
Journal: J Exp Med
Title: Distinct integrin activation pathways for effector and regulatory T cell trafficking and function.
Volume: 218
Issue: 2
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Publication
28137909 | J:244369
 
First Author: Kondo N
Year: 2017
Journal: Mol Cell Biol
Title: NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization.
Volume: 37
Issue: 8
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Publication
25721469 | J:242457
First Author: Qiao S
Year: 2015
Journal: Dev Neurosci
Title: Dab2IP Regulates Neuronal Positioning, Rap1 Activity and Integrin Signaling in the Developing Cortex.
Volume: 37
Issue: 2
Pages: 131-41
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Publication
23230271 | J:194413
First Author: Zou W
Year: 2013
Journal: Mol Cell Biol
Title: Talin1 and Rap1 are critical for osteoclast function.
Volume: 33
Issue: 4
Pages: 830-44
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Publication
29320740 | J:271262
First Author: Zhao XF
Year: 2018
Journal: Cell Rep
Title: PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors.
Volume: 22
Issue: 2
Pages: 456-470
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Publication
37276970 | J:337132
 
First Author: Hiremath C
Year: 2023
Journal: Dev Biol
Title: Rap1 regulates lumen continuity via Afadin in renal epithelia.
Volume: 501
Pages: 20-27
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Publication
25705885 | J:221899
First Author: Stefanini L
Year: 2015
Journal: J Clin Invest
Title: RASA3 is a critical inhibitor of RAP1-dependent platelet activation.
Volume: 125
Issue: 4
Pages: 1419-32
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Publication
20007487 | J:157670
First Author: Glading AJ
Year: 2010
Journal: Dis Model Mech
Title: Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling.
Volume: 3
Issue: 1-2
Pages: 73-83
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Publication
12473665 | J:81907
First Author: Bouschet T
Year: 2003
Journal: J Biol Chem
Title: Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells.
Volume: 278
Issue: 7
Pages: 4778-85
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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