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Search results 1 to 100 out of 347 for Shroom3

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0.044s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Protein Shroom3 (Shrm3) belongs to the Shroom family, whose members are linked to the actin cytoskeleton []. Shrm3 is an actin binding protein that directs Rho kinase- and RhoA-dependent apical constriction in the lens placode and partially facilitates invagination [, , , ]. It is recruited to adherens junctions by cadherin-binding ZA (zonula adherens) protein p120-catenin during lens pit morphogenesis []. It is necessary for neural tube closure in vertebrate development [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Plageman TF Jr
Year: 2010
Journal: Development
Title: Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination.
Volume: 137
Issue: 3
Pages: 405-15
Publication
First Author: Lang RA
Year: 2014
Journal: Development
Title: p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis.
Volume: 141
Issue: 16
Pages: 3177-87
Publication
First Author: Nishimura T
Year: 2008
Journal: Development
Title: Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling.
Volume: 135
Issue: 8
Pages: 1493-502
GXD Expression
Probe: MGI:5811054
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5823715
Age: embryonic day 10.5
Image: S1A - Shroom3 - E10.5
Note: This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud.
Specimen Label: S1A - Shroom3 - E10.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5811054
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823715
Age: embryonic day 11.5
Image: S1A - Shroom3 - E11.5
Note: This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud.
Specimen Label: S1A - Shroom3 - E11.5
Detected: true
Specimen Num: 2
Gene
Type: gene
Organism: human
Publication
First Author: Hildebrand JD
Year: 1999
Journal: Cell
Title: Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice.
Volume: 99
Issue: 5
Pages: 485-97
Publication
First Author: Das D
Year: 2014
Journal: Biol Open
Title: The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice.
Volume: 3
Issue: 9
Pages: 850-60
Publication
First Author: Plageman TF Jr
Year: 2011
Journal: Dev Biol
Title: Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis.
Volume: 357
Issue: 1
Pages: 227-34
Publication
First Author: Plageman TF Jr
Year: 2011
Journal: Development
Title: A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination.
Volume: 138
Issue: 23
Pages: 5177-88
Publication
First Author: Durbin MD
Year: 2020
Journal: Dev Biol
Title: SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects.
Volume: 464
Issue: 2
Pages: 124-136
Publication
First Author: McGreevy EM
Year: 2015
Journal: Biol Open
Title: Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure.
Volume: 4
Issue: 2
Pages: 186-96
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
Publication
First Author: Chu CW
Year: 2013
Journal: PLoS One
Title: Lulu regulates Shroom-induced apical constriction during neural tube closure.
Volume: 8
Issue: 11
Pages: e81854
Publication
First Author: Hildebrand JD
Year: 2005
Journal: J Cell Sci
Title: Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network.
Volume: 118
Issue: Pt 22
Pages: 5191-203
Protein
Organism: Mus musculus/domesticus
Length: 1805  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1849  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1849  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1899  
Fragment?: false
Publication
First Author: Mohan S
Year: 2012
Journal: Mol Biol Cell
Title: Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction.
Volume: 23
Issue: 11
Pages: 2131-42
Protein
Organism: Mus musculus/domesticus
Length: 1986  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1980  
Fragment?: false
UniProt Feature
Begin: 1
Description: Protein Shroom3
Type: chain
End: 1986
Publication
First Author: Matsuura R
Year: 2020
Journal: Sci Rep
Title: SHROOM3, the gene associated with chronic kidney disease, affects the podocyte structure.
Volume: 10
Issue: 1
Pages: 21103
Publication
First Author: Loebel DA
Year: 2016
Journal: Biol Open
Title: Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction.
Volume: 5
Issue: 2
Pages: 130-9
Publication
First Author: Grosse AS
Year: 2011
Journal: Development
Title: Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis.
Volume: 138
Issue: 20
Pages: 4423-32
Publication
First Author: Pieters T
Year: 2020
Journal: BMC Dev Biol
Title: Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice.
Volume: 20
Issue: 1
Pages: 17
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Niswander L
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/03/29
GXD Expression      
Probe: MGI:3037527
Assay Type: Western blot
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3037596
Age: embryonic day 12.5
Specimen Label: Shrm ++
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3037527
Assay Type: Western blot
Annotation Date: 2004-04-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3037596
Age: embryonic day 12.5
Specimen Label: Shrm --
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7531374
Age: embryonic day 12.5
Image: 5
Specimen Label: Dishevelled2<+/+>
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7531374
Age: embryonic day 12.5
Image: 5
Specimen Label: Dishevelled2<+/->
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7531374
Age: embryonic day 12.5
Image: 5
Specimen Label: Dishevelled2<-/->
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7531382
Age: embryonic day 12.5
Image: 5
Specimen Label: Black bar
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7531382
Age: embryonic day 12.5
Image: 5
Specimen Label: White bar
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1732128
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal day 45
Image: S1
Specimen Label: P45 RA
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1731528
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal day 45
Image: S1
Specimen Label: P45 LA
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1734028
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal day 45
Image: S1
Specimen Label: P45 RV
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733728
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal day 45
Image: S1
Specimen Label: P45 LV
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1732128
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal year 1
Image: S1
Specimen Label: 1 yo RA
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1731528
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal year 1
Image: S1
Specimen Label: 1 yo LA
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1734028
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal year 1
Image: S1
Specimen Label: 1 yo RV
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7531180
Assay Type: RT-PCR
Annotation Date: 2023-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733728
Stage: TS28
Assay Id: MGI:7531406
Age: postnatal year 1
Image: S1
Specimen Label: 1 yo LA
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:2682654
Assay Type: RNA in situ
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:2683308
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2682654
Assay Type: RNA in situ
Annotation Date: 2004-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1607111
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2683308
Age: embryonic day 7.5
Image: E7.5
Note: Strong expression occurs in the rostral region of presomitic mesoderm and later in the most posterior somites.
Specimen Label: E7.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:2682654
Assay Type: RNA in situ
Annotation Date: 2004-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1607312
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2683308
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2682654
Assay Type: RNA in situ
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617212
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2683308
Age: embryonic day 8.5
Image: E8.5
Note: Somitic expression persists in older embryos, particularly in cells giving rise to ventral sclerotome.
Specimen Label: E8.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2682654
Assay Type: RNA in situ
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618412
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2683308
Age: embryonic day 8.5
Image: E8.5
Note: Somitic expression persists in older embryos, particularly in cells giving rise to ventral sclerotome.
Specimen Label: E8.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:2682654
Assay Type: RNA in situ
Annotation Date: 2004-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1608915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:2683308
Age: embryonic day 9.5
Image: E9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1607313
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3037557
Age: embryonic day 8.5-8.75
Note: Expression was detected in the cranial neuroepithelium in the rostral portion of the embryo.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624713
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:3037557
Age: embryonic day 8.5-8.75
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618313
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:3037557
Age: embryonic day 8.5-8.75
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616413
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:3037557
Age: embryonic day 8.5-8.75
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1609813
Stage: TS13
Assay Id: MGI:3037557
Age: embryonic day 8.5-8.75
Specimen Label: 2A
Detected: false
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B left
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B left
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B left
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616418
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B left
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618418
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B left
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185718
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Note: Expression was detected in the ventral body wall.
Specimen Label: 2B left
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B right
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B right
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B right
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616418
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B right
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618418
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Specimen Label: 2B right
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185718
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:3037557
Age: embryonic day 10.5
Note: Expression was detected in the ventral body wall.
Specimen Label: 2B right
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3037557
Age: embryonic day 12.5
Specimen Label: 2C
Detected: true
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3037557
Age: embryonic day 14.5
Specimen Label: 2D
Detected: true
Specimen Num: 5
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3037557
Age: embryonic day 14.5
Specimen Label: 2D
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2004-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3037557
Age: embryonic day 14.5
Note: Expression was detected in the distal tips of the digits.
Specimen Label: 2D
Detected: true
Specimen Num: 5