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Search results 101 to 164 out of 164 for Dedd

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Type Details Score
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
12235123 | -
First Author: Lee JC
Year: 2002
Journal: J Cell Biol
Title: DEDD regulates degradation of intermediate filaments during apoptosis.
Volume: 158
Issue: 6
Pages: 1051-66
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Allele
Dedd<em1Smoc> | MGI:7289306
Name: death effector domain-containing; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
11965497 | -
First Author: Zhan Y
Year: 2002
Journal: Cell Death Differ
Title: Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC.
Volume: 9
Issue: 4
Pages: 439-47
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Protein
Q8BRM9
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Publication
11741985 | -
First Author: Roth W
Year: 2002
Journal: J Biol Chem
Title: Identification and characterization of DEDD2, a death effector domain-containing protein.
Volume: 277
Issue: 9
Pages: 7501-8
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Protein Domain
IPR038856 | DEDD/DEDD2
Type: Family
Description: This entry includes death effector domain-containing proteins, DEDD and DEDD2. DEDD is a scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis []. DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway [].
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Protein
Q8BVS4
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: false
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Protein
Q3TUJ2
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Publication
18065403 | -
First Author: Couté Y
Year: 2008
Journal: Mol Cell Proteomics
Title: ISG20L2, a novel vertebrate nucleolar exoribonuclease involved in ribosome biogenesis.
Volume: 7
Issue: 3
Pages: 546-59
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Protein Domain
IPR034933 | ISG20L2
Type: Family
Description: Interferon-stimulated 20kDa exonuclease-like 2 (ISG20L2) is a 3' to 5' exoribonuclease involved in the processing of the 12 S precursor rRNA during ribosome biogenesis. Its N-terminal half promotes nucleolar localization and its C-terminal half contains an exonuclease domain responsible for the exoribonuclease activity. The exonuclease domain belongs to the DEDDh group of the DEDD superfamily [].
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Publication
24880344 | -
First Author: Schäfer IB
Year: 2014
Journal: Nat Struct Mol Biol
Title: The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Volume: 21
Issue: 7
Pages: 591-8
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Protein Domain
IPR028881 | PAN2_UCH_dom
Type: Domain
Description: The poly(A)-specific nuclease (PAN) is a deadenylating enzyme involved in cytoplasmic mRNA turnover and consists of two subunits, PAN2 and PAN3, which form a conserved complex acting in the initial trimming of poly(A) tails, a process followed by the processive action of CCR4-NOT complex. PAN2 is the catalytic subunit and has two independent structural units, the N-terminal assembly unit which engages in a bipartite interaction with PAN3 dimers and the C-terminal catalytic unit [, , ]. The C-terminal unit contains the ubiquitin C-terminal hydrolase (UCH) domain, represented in this entry, and a RNase domain of the DEDD superfamily () [, ].
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Publication
15537391 | J:117524
First Author: Sur R
Year: 2005
Journal: Biochem J
Title: Vanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activation.
Volume: 387
Issue: Pt 2
Pages: 315-24
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Publication
15044470 | J:90734
First Author: Viswanathan P
Year: 2004
Journal: J Biol Chem
Title: Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal.
Volume: 279
Issue: 23
Pages: 23988-95
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Publication
15215893 | -
First Author: Temme C
Year: 2004
Journal: EMBO J
Title: A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila.
Volume: 23
Issue: 14
Pages: 2862-71
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Publication
15769875 | -
First Author: Bianchin C
Year: 2005
Journal: RNA
Title: Conservation of the deadenylase activity of proteins of the Caf1 family in human.
Volume: 11
Issue: 4
Pages: 487-94
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Publication
23388391 | -
First Author: He GJ
Year: 2013
Journal: Biochim Biophys Acta
Title: Distinct roles of the R3H and RRM domains in poly(A)-specific ribonuclease structural integrity and catalysis.
Volume: 1834
Issue: 6
Pages: 1089-98
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Publication
15247430 | -
First Author: Reverdatto SV
Year: 2004
Journal: RNA
Title: mRNA deadenylation by PARN is essential for embryogenesis in higher plants.
Volume: 10
Issue: 8
Pages: 1200-14
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Publication
20379136 | -
First Author: Cevher MA
Year: 2010
Journal: EMBO J
Title: Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage.
Volume: 29
Issue: 10
Pages: 1674-87
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Protein Domain
IPR006941 | RNase_CAF1
Type: Family
Description: The major pathways of mRNA turnover in eukaryotes initiate with shortening of the poly(A) tail. CAF1 (also known as CCR4-associated factor 1) is an RNase of the DEDD superfamily, and a subunit of the CCR4-NOT complex that mediates 3' to 5' mRNA deadenylation [, ]. In yeast, CAF1 () is also known as POP2, and encodes a critical component of the major cytoplasmic deadenylase [, ]. It is required for normal mRNA deadenylation in vivoand localises to the cytoplasm. CAF1 copurifies with a CCR4-dependent poly(A)-specific exonuclease activity. The crystal structure of Saccharomyces cerevisiae POP2 has been resolved [].Some members of this family contain a single-stranded nucleic acid binding domain, R3H, such aspoly(A)-specific ribonuclease (PARN), which also contains an RRM domain []. PARN is only conserved in vertebrates and may be important in regulated deadenylation such as early developmentand DNA damage response [, ].
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Publication
14618157 | -
First Author: Thore S
Year: 2003
Journal: EMBO Rep
Title: X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex.
Volume: 4
Issue: 12
Pages: 1150-5
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Publication
11410650 | -
First Author: Daugeron MC
Year: 2001
Journal: Nucleic Acids Res
Title: The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation.
Volume: 29
Issue: 12
Pages: 2448-55
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Protein
Q9Z1L3
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
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Protein
Q8QZV0
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
D3Z0I1
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: true
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Protein
Q3UYN3
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
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Protein
D3Z4Q1
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
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Protein
Q3U001
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
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Protein
D3Z0F7
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: true
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Publication
8550599 | -
First Author: Boeck R
Year: 1996
Journal: J Biol Chem
Title: The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity.
Volume: 271
Issue: 1
Pages: 432-8
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Publication
24880343 | -
First Author: Jonas S
Year: 2014
Journal: Nat Struct Mol Biol
Title: An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay.
Volume: 21
Issue: 7
Pages: 599-608
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Protein
Q60809
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Protein
Q9D8X5
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Protein
B2RXZ1
Organism: Mus musculus/domesticus
Length: 531  
Fragment?: false
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Protein
F6ZMT3
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: true
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Protein
Q3TLK9
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Protein
Q3V476
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: false
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Protein
A0A2R8VHG7
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
Q3V231
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Protein
A0A3B2WD69
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: true
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Protein
A0A3B2WCF7
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
A0A3B2WCS3
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Protein
Q3UTD2
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
Q543X5
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Publication
11239395 | -
First Author: Tucker M
Year: 2001
Journal: Cell
Title: The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae.
Volume: 104
Issue: 3
Pages: 377-86
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Protein
Q3U1G5
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
A0A0R4J0R3
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
A0A2R8VKA3
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Protein
Q9D2E2
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
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Protein
Q80XN5
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Protein
Q8BGF7
Organism: Mus musculus/domesticus
Length: 1200  
Fragment?: false
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Protein
Q8VDG3
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Protein
Q3TUQ8
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Protein
A0A0R4J0P6
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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