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Search results 201 to 300 out of 308 for Dapk1

0.045s
Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304897
Specimen Label: MRC Harwell_1304897
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Female
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: false
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304898
Specimen Label: MRC Harwell_1304898
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:2694228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304876
Specimen Label: MRC Harwell_1304876
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304877
Specimen Label: MRC Harwell_1304877
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3667028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304878
Specimen Label: MRC Harwell_1304878
Detected: true
Specimen Num: 21
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304878
Specimen Label: MRC Harwell_1304878
Detected: true
Specimen Num: 21
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304879
Specimen Label: MRC Harwell_1304879
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304879
Specimen Label: MRC Harwell_1304879
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691881
Age: postnatal adult
Image: MRC Harwell_1304880
Specimen Label: MRC Harwell_1304880
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:4423327
Assay Type: RNA in situ
Annotation Date: 2024-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7577420
Age: embryonic day 14.5
Note: Cortical plate expression was greater than in the ventricular zone.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4423327
Assay Type: RNA in situ
Annotation Date: 2024-01-29
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7577420
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Deiss LP
Year: 1995
Journal: Genes Dev
Title: Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.
Volume: 9
Issue: 1
Pages: 15-30
Publication
First Author: Kang BN
Year: 2010
Journal: J Neurosci
Title: Death-associated protein kinase-mediated cell death modulated by interaction with DANGER.
Volume: 30
Issue: 1
Pages: 93-8
Publication
First Author: Fang J
Year: 2008
Journal: Blood
Title: Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.
Volume: 112
Issue: 3
Pages: 886-90
Publication
First Author: Cheng MB
Year: 2020
Journal: Stem Cell Res Ther
Title: Hyperthermia depletes Oct4 in mouse blastocysts and stem cells.
Volume: 11
Issue: 1
Pages: 195
Publication  
First Author: Chou TF
Year: 2016
Journal: Nat Commun
Title: Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression.
Volume: 7
Pages: 11904
Publication
First Author: Capoccia BJ
Year: 2013
Journal: J Clin Invest
Title: The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation.
Volume: 123
Issue: 4
Pages: 1475-91
Publication
First Author: Chuang YT
Year: 2011
Journal: Blood
Title: Tumor suppressor death-associated protein kinase is required for full IL-1β production.
Volume: 117
Issue: 3
Pages: 960-70
Publication
First Author: Arif A
Year: 2012
Journal: Mol Cell Biol
Title: Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.
Volume: 32
Issue: 24
Pages: 5046-55
Publication
First Author: Nagamori I
Year: 2006
Journal: J Biol Chem
Title: Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.
Volume: 281
Issue: 22
Pages: 15073-81
Publication
First Author: Liu P
Year: 2006
Journal: Nat Genet
Title: Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.
Volume: 38
Issue: 8
Pages: 888-95
Publication
First Author: Barsi JC
Year: 2005
Journal: Mech Dev
Title: Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling.
Volume: 122
Issue: 10
Pages: 1106-17
Publication
First Author: Umansky KB
Year: 2015
Journal: PLoS Genet
Title: Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration.
Volume: 11
Issue: 8
Pages: e1005457
Publication  
First Author: Spies N
Year: 2015
Journal: Elife
Title: Constraint and divergence of global gene expression in the mammalian embryo.
Volume: 4
Pages: e05538
Publication
First Author: Svandova EB
Year: 2017
Journal: Histochem Cell Biol
Title: Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.
Volume: 147
Issue: 4
Pages: 497-510
Publication
First Author: Wang CX
Year: 2018
Journal: PLoS Biol
Title: METTL3-mediated m6A modification is required for cerebellar development.
Volume: 16
Issue: 6
Pages: e2004880
Publication
First Author: Munger SC
Year: 2009
Journal: Genes Dev
Title: Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.
Volume: 23
Issue: 21
Pages: 2521-36
Publication
First Author: Warden CH
Year: 1993
Journal: Genomics
Title: Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.
Volume: 18
Issue: 2
Pages: 295-307
Publication
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
Publication      
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
Publication
First Author: Welch CL
Year: 1996
Journal: J Lipid Res
Title: Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.
Volume: 37
Issue: 7
Pages: 1406-21
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Willemsen J
Year: 2017
Journal: Mol Cell
Title: Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening.
Volume: 65
Issue: 3
Pages: 403-415.e8
Publication  
First Author: Wang S
Year: 2020
Journal: Exp Neurol
Title: Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.
Volume: 329
Pages: 113303
UniProt Feature
Begin: 313
Description: Phosphoserine; by DAPK1
Type: modified residue
End: 313
UniProt Feature
Begin: 321
Description: Phosphoserine; by DAPK1
Type: modified residue
End: 321
UniProt Feature
Begin: 304
Description: Phosphoserine; by DAPK1
Type: modified residue
End: 304
UniProt Feature
Begin: 307
Description: Phosphoserine; by DAPK1
Type: modified residue
End: 307
UniProt Feature
Begin: 117
Description: Phosphothreonine; by DAPK1
Type: modified residue
End: 117
UniProt Feature
Begin: 188
Description: Phosphoserine; by DAPK1
Type: modified residue
End: 188
UniProt Feature
Begin: 1303
Description: Phosphoserine; by DAPK1
Type: modified residue
End: 1303
Publication
First Author: Mebratu YA
Year: 2017
Journal: Nat Commun
Title: Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria.
Volume: 8
Issue: 1
Pages: 803
UniProt Feature
Begin: 306
Description: Phosphoserine; by autocatalysis and DAPK1
Type: modified residue
End: 306
UniProt Feature
Begin: 235
Description: Phosphoserine; by RPS6KA1, RPS6KA3, DAPK1 and PASK
Type: modified residue
End: 235
UniProt Feature
Begin: 236
Description: Phosphoserine; by RPS6KA1, RPS6KA3, DAPK1 and PASK
Type: modified residue
End: 236
Publication
First Author: Chen Z
Year: 2019
Journal: Structure
Title: Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Volume: 27
Issue: 9
Pages: 1395-1404.e4
Publication  
First Author: Mitsui Y
Year: 2015
Journal: BMC Cancer
Title: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma.
Volume: 15
Pages: 942
GO Term
Publication
First Author: McNamara LK
Year: 2009
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structural insight into nucleotide recognition by human death-associated protein kinase.
Volume: 65
Issue: Pt 3
Pages: 241-8
Publication
First Author: Kögel D
Year: 2001
Journal: Bioessays
Title: The DAP kinase family of pro-apoptotic proteins: novel players in the apoptotic game.
Volume: 23
Issue: 4
Pages: 352-8
Publication
First Author: Shiloh R
Year: 2014
Journal: Apoptosis
Title: The DAPK family: a structure-function analysis.
Volume: 19
Issue: 2
Pages: 286-97
Protein Domain
Type: Domain
Description: This entry represents the catalytic domain of DAPK3, which is a member of the Ca(2+)/calmodulin-regulated family of serine/threonine protein kinases [, ].STKs (serine/threonine kinases) catalyse the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. DAPKs mediate cell death and act as tumour suppressors. They are necessary to induce cell death and their overexpression leads to death-associated changes including membrane blebbing, cell rounding, and formation of autophagic vesicles []. Vertebrates contain three subfamily members with different domain architecture, localization, and function. DAPK1 is the prototypical member of the DAPK family and is also simply referred to as DAPK. DAPK2 is also called DAPK-related protein 1 (DRP-1), while DAPK3 has also been named DAP-like kinase (DLK) and zipper-interacting protein kinase (ZIPk). These proteins are ubiquitously expressed in adult tissues, are capable of cross talk with each other, and may act synergistically in regulating cell death [].