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Search results 1 to 100 out of 127 for Irak4

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Category: Publication
Type Details Score
Publication
First Author: Ku CL
Year: 2007
Journal: J Med Genet
Title: IRAK4 and NEMO mutations in otherwise healthy children with recurrent invasive pneumococcal disease.
Volume: 44
Issue: 1
Pages: 16-23
Publication
First Author: Loiarro M
Year: 2007
Journal: J Leukoc Biol
Title: Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.
Volume: 82
Issue: 4
Pages: 801-10
Publication
First Author: Murphy M
Year: 2017
Journal: Eur J Immunol
Title: Deficiency in IRAK4 activity attenuates manifestations of murine Lupus.
Volume: 47
Issue: 5
Pages: 880-891
Publication
First Author: Rekhter M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation.
Volume: 367
Issue: 3
Pages: 642-8
Publication
First Author: Day N
Year: 2004
Journal: J Pediatr
Title: Interleukin receptor-associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses.
Volume: 144
Issue: 4
Pages: 524-6
Publication  
First Author: Li Q
Year: 2019
Journal: JCI Insight
Title: IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer.
Volume: 4
Issue: 19
Publication      
First Author: Berger M
Year: 2008
Journal: MGI Direct Data Submission
Title: Otiose is an allele of Irak4 and has TLR-signaling defects
Publication
First Author: Neumann D
Year: 2008
Journal: J Leukoc Biol
Title: Threonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation.
Volume: 84
Issue: 3
Pages: 807-13
Publication
First Author: Strelow A
Year: 2003
Journal: FEBS Lett
Title: Characterization of Pellino2, a substrate of IRAK1 and IRAK4.
Volume: 547
Issue: 1-3
Pages: 157-61
Publication
First Author: Staschke KA
Year: 2009
Journal: J Immunol
Title: IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease.
Volume: 183
Issue: 1
Pages: 568-77
Publication  
First Author: Picard A
Year: 2022
Journal: Mol Metab
Title: Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion.
Volume: 61
Pages: 101479
Publication
First Author: Xiong Y
Year: 2013
Journal: J Leukoc Biol
Title: IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance.
Volume: 94
Issue: 2
Pages: 291-300
Publication
First Author: Pattabiraman G
Year: 2018
Journal: J Leukoc Biol
Title: IRAK4 activity controls immune responses to intracellular bacteria Listeria monocytogenes and Mycobacterium smegmatis.
Volume: 104
Issue: 4
Pages: 811-820
Publication
First Author: Kim TW
Year: 2007
Journal: J Exp Med
Title: A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.
Volume: 204
Issue: 5
Pages: 1025-36
Publication
First Author: Somani VK
Year: 2022
Journal: Gastroenterology
Title: IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma.
Volume: 162
Issue: 7
Pages: 2047-2062
Publication
First Author: Trumstedt C
Year: 2007
Journal: J Leukoc Biol
Title: Role of IRAK4 and IRF3 in the control of intracellular infection with Chlamydia pneumoniae.
Volume: 81
Issue: 6
Pages: 1591-8
Publication
First Author: Leaf IA
Year: 2017
Journal: J Clin Invest
Title: Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury.
Volume: 127
Issue: 1
Pages: 321-334
Publication
First Author: Pennini ME
Year: 2013
Journal: J Immunol
Title: Complete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive mice.
Volume: 190
Issue: 1
Pages: 307-16
Publication
First Author: Nanda SK
Year: 2016
Journal: J Immunol
Title: Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1.
Volume: 197
Issue: 11
Pages: 4266-4273
Publication
First Author: Cameron B
Year: 2012
Journal: J Neurosci
Title: Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.
Volume: 32
Issue: 43
Pages: 15112-23
Publication
First Author: Béla SR
Year: 2012
Journal: Infect Immun
Title: Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii.
Volume: 80
Issue: 12
Pages: 4298-308
Publication
First Author: Katsuyama E
Year: 2015
Journal: J Biol Chem
Title: Interleukin-1 receptor-associated kinase-4 (IRAK4) promotes inflammatory osteolysis by activating osteoclasts and inhibiting formation of foreign body giant cells.
Volume: 290
Issue: 2
Pages: 716-26
Publication
First Author: Dou H
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: A novel benzenediamine derivate rescued mice from experimental sepsis by attenuating proinflammatory mediators via IRAK4.
Volume: 51
Issue: 2
Pages: 191-200
Publication
First Author: Fraczek J
Year: 2008
Journal: J Biol Chem
Title: The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation.
Volume: 283
Issue: 46
Pages: 31697-705
Publication
First Author: Kim TW
Year: 2011
Journal: J Immunol
Title: The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis.
Volume: 186
Issue: 5
Pages: 2871-80
Publication
First Author: Sun J
Year: 2016
Journal: Sci Signal
Title: Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Volume: 9
Issue: 409
Pages: ra3
Publication
First Author: De Nardo D
Year: 2018
Journal: J Biol Chem
Title: Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.
Volume: 293
Issue: 39
Pages: 15195-15207
Publication
First Author: Fernandes-Alnemri T
Year: 2013
Journal: J Immunol
Title: Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome.
Volume: 191
Issue: 8
Pages: 3995-9
Publication
First Author: Macedo L
Year: 2007
Journal: Am J Pathol
Title: Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors.
Volume: 171
Issue: 6
Pages: 1774-88
Publication
First Author: Valaperti A
Year: 2013
Journal: Circulation
Title: Innate immune interleukin-1 receptor-associated kinase 4 exacerbates viral myocarditis by reducing CCR5(+) CD11b(+) monocyte migration and impairing interferon production.
Volume: 128
Issue: 14
Pages: 1542-54
Publication
First Author: Suzuki N
Year: 2006
Journal: Science
Title: A critical role for the innate immune signaling molecule IRAK-4 in T cell activation.
Volume: 311
Issue: 5769
Pages: 1927-32
Publication
First Author: Koziczak-Holbro M
Year: 2007
Journal: J Biol Chem
Title: IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression.
Volume: 282
Issue: 18
Pages: 13552-60
Publication
First Author: Lye E
Year: 2008
Journal: Eur J Immunol
Title: IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses.
Volume: 38
Issue: 3
Pages: 870-6
Publication
First Author: Koziczak-Holbro M
Year: 2008
Journal: Eur J Immunol
Title: IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes.
Volume: 38
Issue: 3
Pages: 788-96
Publication
First Author: Suzuki N
Year: 2003
Journal: J Immunol
Title: IL-1 receptor-associated kinase 4 is essential for IL-18-mediated NK and Th1 cell responses.
Volume: 170
Issue: 8
Pages: 4031-5
Publication
First Author: Maekawa Y
Year: 2009
Journal: Circulation
Title: Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells.
Volume: 120
Issue: 14
Pages: 1401-14
Publication
First Author: Li S
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase.
Volume: 99
Issue: 8
Pages: 5567-72
Publication  
First Author: Dzietko M
Year: 2015
Journal: Biomed Res Int
Title: Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain.
Volume: 2015
Pages: 318306
Publication
First Author: Brzezinska AA
Year: 2009
Journal: Immunology
Title: Signalling mechanisms for Toll-like receptor-activated neutrophil exocytosis: key roles for interleukin-1-receptor-associated kinase-4 and phosphatidylinositol 3-kinase but not Toll/IL-1 receptor (TIR) domain-containing adaptor inducing IFN-beta (TRIF).
Volume: 127
Issue: 3
Pages: 386-97
Publication  
First Author: Mancini SJ
Year: 2017
Journal: Mol Cell Endocrinol
Title: Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation.
Volume: 440
Pages: 44-56
Publication
First Author: Oliveira FS
Year: 2011
Journal: Infect Immun
Title: Interleukin-1 receptor-associated kinase 4 is essential for initial host control of Brucella abortus infection.
Volume: 79
Issue: 11
Pages: 4688-95
Publication
First Author: Burns K
Year: 2003
Journal: J Exp Med
Title: Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4.
Volume: 197
Issue: 2
Pages: 263-8
Publication
First Author: Mendoza-Barberá E
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Contribution of globular death domains and unstructured linkers to MyD88.IRAK-4 heterodimer formation: an explanation for the antagonistic activity of MyD88s.
Volume: 380
Issue: 1
Pages: 183-7
Publication
First Author: Erdman LK
Year: 2009
Journal: J Immunol
Title: CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria.
Volume: 183
Issue: 10
Pages: 6452-9
Publication
First Author: Kawagoe T
Year: 2007
Journal: J Exp Med
Title: Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling.
Volume: 204
Issue: 5
Pages: 1013-24
Publication
First Author: Lin KM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.
Volume: 111
Issue: 2
Pages: 775-80
Publication
First Author: Bonham KS
Year: 2014
Journal: Cell
Title: A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.
Volume: 156
Issue: 4
Pages: 705-16
Publication
First Author: Zhou H
Year: 2013
Journal: EMBO J
Title: IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production.
Volume: 32
Issue: 4
Pages: 583-96
Publication
First Author: Mun HS
Year: 2005
Journal: Infect Immun
Title: Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70.
Volume: 73
Issue: 8
Pages: 4634-42
Publication
First Author: Siggs OM
Year: 2012
Journal: Blood
Title: iRhom2 is required for the secretion of mouse TNFα.
Volume: 119
Issue: 24
Pages: 5769-71
Publication
First Author: Lemay AM
Year: 2005
Journal: Physiol Genomics
Title: Bleomycin-induced pulmonary fibrosis susceptibility genes in AcB/BcA recombinant congenic mice.
Volume: 23
Issue: 1
Pages: 54-61
Publication
First Author: Pereira M
Year: 2024
Journal: Cell Rep
Title: The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.
Volume: 43
Issue: 2
Pages: 113795
Publication
First Author: Häcker H
Year: 2006
Journal: Nature
Title: Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6.
Volume: 439
Issue: 7073
Pages: 204-7
Publication
First Author: Harada M
Year: 2006
Journal: J Exp Med
Title: IL-21-induced Bepsilon cell apoptosis mediated by natural killer T cells suppresses IgE responses.
Volume: 203
Issue: 13
Pages: 2929-37
Publication
First Author: Croker BA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger.
Volume: 105
Issue: 39
Pages: 15028-33
Publication
First Author: Mertins P
Year: 2017
Journal: Cell Rep
Title: An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling.
Volume: 19
Issue: 13
Pages: 2853-2866
Publication
First Author: Lye E
Year: 2004
Journal: J Biol Chem
Title: The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling.
Volume: 279
Issue: 39
Pages: 40653-8
Publication
First Author: Lu YC
Year: 2009
Journal: J Immunol
Title: Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines.
Volume: 182
Issue: 11
Pages: 7212-21
Publication
First Author: Zhou J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease.
Volume: 108
Issue: 44
Pages: E998-1006
Publication
First Author: Suzuki N
Year: 2002
Journal: Nature
Title: Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4.
Volume: 416
Issue: 6882
Pages: 750-6
Publication
First Author: Wang Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Volume: 113
Issue: 7
Pages: E884-93
Publication
First Author: Mager LF
Year: 2015
Journal: J Clin Invest
Title: IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.
Volume: 125
Issue: 7
Pages: 2579-91
Publication
First Author: Hoebe K
Year: 2003
Journal: J Endotoxin Res
Title: Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening.
Volume: 9
Issue: 4
Pages: 250-5
Publication
First Author: Choi JH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.
Volume: 114
Issue: 7
Pages: E1196-E1204
Publication
First Author: Kim YI
Year: 2008
Journal: J Biol Chem
Title: CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases.
Volume: 283
Issue: 22
Pages: 15258-70
Publication
First Author: Blasius AL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.
Volume: 107
Issue: 46
Pages: 19973-8
Publication
First Author: Orelio C
Year: 2008
Journal: Blood
Title: Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo.
Volume: 112
Issue: 13
Pages: 4895-904
Publication
First Author: Bauernfeind FG
Year: 2009
Journal: J Immunol
Title: Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Volume: 183
Issue: 2
Pages: 787-91
Publication
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
Publication      
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform