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Search results 201 to 300 out of 423 for Pdpk1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_12
Specimen Label: euxassay_001988_12
Detected: true
Specimen Num: 12
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_13
Specimen Label: euxassay_001988_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884768
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945652
Age: embryonic day 15.5
Image: g01192 E15.5
Specimen Label: g01192 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884768
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945652
Age: postnatal day 7
Image: g01192 P7
Note: Expression was region specific and scattered.
Specimen Label: g01192 P7
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:1028779
Assay Type: RNA in situ
Annotation Date: 2017-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5819050
Age: embryonic day 13.5
Image: 3D
Specimen Label: 3D
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1028779
Assay Type: RNA in situ
Annotation Date: 2017-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5819050
Age: embryonic day 13.5
Image: 3H
Specimen Label: 3H
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1028779
Assay Type: RNA in situ
Annotation Date: 2017-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5819050
Age: embryonic day 17.5
Image: 4D
Specimen Label: 4D
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1028779
Assay Type: RNA in situ
Annotation Date: 2017-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5819050
Age: embryonic day 14.5
Specimen Label: not shown
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_07
Specimen Label: euxassay_001988_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_08
Specimen Label: euxassay_001988_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_15
Specimen Label: euxassay_001988_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1028779
Assay Type: RNA in situ
Annotation Date: 2017-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5819050
Age: embryonic day 13.5
Image: 3H
Specimen Label: 3H
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_01
Specimen Label: euxassay_001988_01
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_02
Specimen Label: euxassay_001988_02
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_03
Specimen Label: euxassay_001988_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_04
Specimen Label: euxassay_001988_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_05
Specimen Label: euxassay_001988_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_06
Specimen Label: euxassay_001988_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_07
Specimen Label: euxassay_001988_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_08
Specimen Label: euxassay_001988_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_09
Specimen Label: euxassay_001988_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_10
Specimen Label: euxassay_001988_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_11
Specimen Label: euxassay_001988_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_12
Specimen Label: euxassay_001988_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_13
Specimen Label: euxassay_001988_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_14
Specimen Label: euxassay_001988_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_15
Specimen Label: euxassay_001988_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_16
Specimen Label: euxassay_001988_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_17
Specimen Label: euxassay_001988_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_18
Specimen Label: euxassay_001988_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_19
Specimen Label: euxassay_001988_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_20
Specimen Label: euxassay_001988_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_21
Specimen Label: euxassay_001988_21
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1000606
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827136
Age: embryonic day 14.5
Image: euxassay_001988_22
Specimen Label: euxassay_001988_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1028779
Assay Type: RNA in situ
Annotation Date: 2017-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5819050
Age: embryonic day 13.5
Image: 3D
Specimen Label: 3D
Detected: true
Specimen Num: 3
•
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Publication
17371830 | J:134712
First Author: Primo L
Year: 2007
Journal: J Cell Biol
Title: Essential role of PDK1 in regulating endothelial cell migration.
Volume: 176
Issue: 7
Pages: 1035-47
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Publication
19047061 | J:146938
First Author: Wang C
Year: 2009
Journal: J Biol Chem
Title: Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance.
Volume: 284
Issue: 4
Pages: 2038-44
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Publication
21074460 | J:166834
First Author: Park SG
Year: 2010
Journal: Immunity
Title: T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells.
Volume: 33
Issue: 5
Pages: 791-803
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Publication
24979759 | J:212161
First Author: Baracho GV
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PDK1 regulates B cell differentiation and homeostasis.
Volume: 111
Issue: 26
Pages: 9573-8
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Publication
29104535 | J:276535
 
First Author: Xu C
Year: 2017
Journal: Front Cell Neurosci
Title: Conditional Deletion of PDK1 in the Forebrain Causes Neuron Loss and Increased Apoptosis during Cortical Development.
Volume: 11
Pages: 330
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Publication
16831426 | J:111423
First Author: Smith TG
Year: 2006
Journal: FEBS Lett
Title: Negative feedback predominates over cross-regulation to control ERK MAPK activity in response to FGF signalling in embryos.
Volume: 580
Issue: 17
Pages: 4242-5
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Publication
16825708 | J:116874
First Author: Sandu C
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.
Volume: 291
Issue: 5
Pages: G868-76
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Publication
26455327 | J:226089
First Author: Du J
Year: 2016
Journal: Oncogene
Title: PDK1 promotes tumor growth and metastasis in a spontaneous breast cancer model.
Volume: 35
Issue: 25
Pages: 3314-23
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Publication
32048762 | J:310893
First Author: Xiao D
Year: 2020
Journal: J Cell Biochem
Title: PDK1 is important lipid kinase for RANKL-induced osteoclast formation and function via the regulation of the Akt-GSK3β-NFATc1 signaling cascade.
Volume: 121
Issue: 11
Pages: 4542-4557
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Publication
23463102 | J:195305
First Author: Venigalla RK
Year: 2013
Journal: EMBO J
Title: PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
Volume: 32
Issue: 7
Pages: 1008-22
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Publication
31578203 | J:282101
First Author: Geue S
Year: 2019
Journal: Blood
Title: Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis.
Volume: 134
Issue: 21
Pages: 1847-1858
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Publication
28694518 | J:270960
First Author: Hu T
Year: 2017
Journal: Sci Rep
Title: PDK1 plays a vital role on hematopoietic stem cell function.
Volume: 7
Issue: 1
Pages: 4943
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Publication
32487697 | J:291516
First Author: Liu R
Year: 2020
Journal: J Neurosci
Title: PDK1 Regulates the Maintenance of Cell Body and the Development of Dendrites of Purkinje Cells by pS6 and PKCγ.
Volume: 40
Issue: 29
Pages: 5531-5548
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Publication
23131847 | J:259483
First Author: Kikani CK
Year: 2012
Journal: Sci Signal
Title: Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis.
Volume: 5
Issue: 249
Pages: ra80
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Publication
15187024 | J:93757
First Author: Yamazaki T
Year: 2004
Journal: Blood
Title: Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis.
Volume: 104
Issue: 8
Pages: 2345-52
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Publication
17456549 | J:124173
First Author: Bone HK
Year: 2007
Journal: J Cell Sci
Title: Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis.
Volume: 120
Issue: Pt 10
Pages: 1752-62
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Publication
22544756 | J:192998
First Author: Seong HA
Year: 2012
Journal: J Biol Chem
Title: PDK1 protein phosphorylation at Thr354 by murine protein serine-threonine kinase 38 contributes to negative regulation of PDK1 protein activity.
Volume: 287
Issue: 25
Pages: 20811-22
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Publication
31208986 | J:278386
First Author: Li C
Year: 2019
Journal: Biochem J
Title: Metabolic remodeling of cardiomyocytes identified in phosphoinositide-dependent kinase 1-deficient mice.
Volume: 476
Issue: 13
Pages: 1943-1954
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Publication
17599070 | J:123268
First Author: Kelly AP
Year: 2007
Journal: EMBO J
Title: Notch-induced T cell development requires phosphoinositide-dependent kinase 1.
Volume: 26
Issue: 14
Pages: 3441-50
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Publication
19429709 | J:150014
First Author: Ito K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PDK1 coordinates survival pathways and beta-adrenergic response in the heart.
Volume: 106
Issue: 21
Pages: 8689-94
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Publication
18347057 | J:136089
First Author: Bayascas JR
Year: 2008
Journal: Mol Cell Biol
Title: Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Volume: 28
Issue: 10
Pages: 3258-72
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Publication
29358916 | J:310530
 
First Author: Yang S
Year: 2017
Journal: Front Aging Neurosci
Title: Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides.
Volume: 9
Pages: 435
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Publication
19703999 | J:153995
First Author: Waugh C
Year: 2009
Journal: Mol Cell Biol
Title: Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation.
Volume: 29
Issue: 21
Pages: 5952-62
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Publication
30622306 | J:295469
First Author: He J
Year: 2019
Journal: Cell Death Differ
Title: Stage-specific requirement of kinase PDK1 for NK cells development and activation.
Volume: 26
Issue: 10
Pages: 1918-1928
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Publication
28462077 | J:271913
First Author: Sasanuma H
Year: 2017
Journal: Mol Metab
Title: PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis.
Volume: 6
Issue: 5
Pages: 428-439
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Publication
20687898 | J:166171
First Author: Mouton V
Year: 2010
Journal: Biochem J
Title: Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3).
Volume: 431
Issue: 2
Pages: 267-75
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Publication
28137869 | J:240937
First Author: Rogel A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance.
Volume: 114
Issue: 7
Pages: E1178-E1187
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Publication
33276084 | J:301062
 
First Author: Wang H
Year: 2021
Journal: Neurobiol Dis
Title: Deletion of PDK1 in oligodendrocyte lineage cells causes white matter abnormality and myelination defect in the central nervous system.
Volume: 148
Pages: 105212
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Publication
21034549 | J:168636
First Author: Di RM
Year: 2010
Journal: Chin Med J (Engl)
Title: PDK1 plays a critical role in regulating cardiac function in mice and human.
Volume: 123
Issue: 17
Pages: 2358-63
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Publication
29991705 | J:268502
First Author: Zhang B
Year: 2018
Journal: Sci Rep
Title: Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation.
Volume: 8
Issue: 1
Pages: 10415
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Publication
17267763 | J:122117
First Author: Okamoto Y
Year: 2007
Journal: Diabetes
Title: Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1.
Volume: 56
Issue: 4
Pages: 1000-9
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Publication
11964154 | J:76536
First Author: Cenni V
Year: 2002
Journal: Biochem J
Title: Regulation of novel protein kinase C epsilon by phosphorylation.
Volume: 363
Issue: Pt 3
Pages: 537-45
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Publication
16785309 | J:124408
First Author: Nirula A
Year: 2006
Journal: J Exp Med
Title: Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4.
Volume: 203
Issue: 7
Pages: 1733-44
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Publication
19920149 | J:159953
First Author: Seong HA
Year: 2010
Journal: J Biol Chem
Title: Reciprocal negative regulation of PDK1 and ASK1 signaling by direct interaction and phosphorylation.
Volume: 285
Issue: 4
Pages: 2397-414
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Publication
27103434 | J:235166
First Author: Mäemets-Allas K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: The inhibition of Akt-Pdpk1 interaction efficiently suppresses the growth of murine primary liver tumor cells.
Volume: 474
Issue: 1
Pages: 118-125
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Publication
31894307 | J:324075
First Author: Gao J
Year: 2020
Journal: Int J Mol Med
Title: Deficiency of Pdk1 contributes to primordial follicle activation via the upregulation of YAP expression and the pro‑inflammatory response.
Volume: 45
Issue: 2
Pages: 647-657
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Publication
21059917 | J:166594
First Author: Liu J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1.
Volume: 107
Issue: 47
Pages: 20494-9
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Publication
20584979 | J:163291
First Author: Chaurasia B
Year: 2010
Journal: Mol Cell Biol
Title: Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages.
Volume: 30
Issue: 17
Pages: 4354-66
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Publication
16337591 | J:121227
First Author: Michel JJ
Year: 2005
Journal: Mol Cell
Title: Spatial restriction of PDK1 activation cascades by anchoring to mAKAPalpha.
Volume: 20
Issue: 5
Pages: 661-72
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Publication
19122654 | J:144512
First Author: Park SG
Year: 2009
Journal: Nat Immunol
Title: The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.
Volume: 10
Issue: 2
Pages: 158-66
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Publication
21493594 | J:170965
First Author: Ellwood-Yen K
Year: 2011
Journal: Cancer Res
Title: PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
Volume: 71
Issue: 8
Pages: 3052-65
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Publication
38091840 | J:344742
 
First Author: Imamori M
Year: 2024
Journal: Biochem Biophys Res Commun
Title: Thrombospondin-1 promotes liver fibrosis by enhancing TGF-β action in hepatic stellate cells.
Volume: 693
Pages: 149369
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Publication
18396135 | J:134336
First Author: Belgardt BF
Year: 2008
Journal: Cell Metab
Title: PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.
Volume: 7
Issue: 4
Pages: 291-301
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Publication
22147265 | J:195605
First Author: Sperow M
Year: 2012
Journal: J Physiol
Title: Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration.
Volume: 590
Issue: 4
Pages: 777-92
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Publication
29705701 | J:270325
First Author: Zhang B
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Protective role of AgRP neuron's PDK1 against salt-induced hypertension.
Volume: 500
Issue: 4
Pages: 910-916
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Publication
21694754 | J:274061
First Author: Cao Y
Year: 2011
Journal: PLoS One
Title: PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure.
Volume: 6
Issue: 4
Pages: e18324
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Publication
26099023 | J:226194
First Author: Yu M
Year: 2015
Journal: J Invest Dermatol
Title: Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease.
Volume: 135
Issue: 11
Pages: 2688-2696
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Publication
24662050 | J:215360
First Author: Zhao X
Year: 2014
Journal: Mol Cell Biol
Title: Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.
Volume: 34
Issue: 11
Pages: 1966-75
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Publication
30951706 | J:276572
First Author: Jin H
Year: 2019
Journal: Dev Biol
Title: Differential contribution of the two waves of cardiac progenitors and their derivatives to aorta and pulmonary artery.
Volume: 450
Issue: 2
Pages: 82-89
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Publication
26401001 | J:269887
First Author: Zaru R
Year: 2015
Journal: J Immunol
Title: The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.
Volume: 195
Issue: 9
Pages: 4264-72
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Publication
16642023 | J:109010
First Author: Hashimoto N
Year: 2006
Journal: Nat Genet
Title: Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass.
Volume: 38
Issue: 5
Pages: 589-93
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Publication
18430722 | J:138078
First Author: Nakamura K
Year: 2008
Journal: J Biol Chem
Title: PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression.
Volume: 283
Issue: 25
Pages: 17702-11
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Publication
33568757 | J:305717
First Author: Kuramoto N
Year: 2021
Journal: Sci Rep
Title: Role of PDK1 in skeletal muscle hypertrophy induced by mechanical load.
Volume: 11
Issue: 1
Pages: 3447
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Publication
12711546 | J:83323
First Author: Kohn M
Year: 2003
Journal: Gene Expr Patterns
Title: Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis.
Volume: 3
Issue: 2
Pages: 173-7
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Publication
37561545 | J:346253
First Author: Li C
Year: 2023
Journal: FASEB J
Title: Deficiency of Pdk1 drives heart failure by impairing taurine homeostasis through Slc6a6.
Volume: 37
Issue: 9
Pages: e23134
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Publication
23955714 | J:202038
First Author: Pietri M
Year: 2013
Journal: Nat Med
Title: PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases.
Volume: 19
Issue: 9
Pages: 1124-31
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Publication
22133875 | J:184575
First Author: Shim JH
Year: 2012
Journal: J Clin Invest
Title: Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.
Volume: 122
Issue: 1
Pages: 91-106
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Publication
19843540 | J:155357
First Author: Adhikari D
Year: 2010
Journal: Hum Mol Genet
Title: Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles.
Volume: 19
Issue: 3
Pages: 397-410
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Publication
21705713 | J:175082
First Author: Braeuning A
Year: 2011
Journal: Toxicol Sci
Title: Gender-specific interplay of signaling through β-catenin and CAR in the regulation of xenobiotic-induced hepatocyte proliferation.
Volume: 123
Issue: 1
Pages: 113-22
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Publication
34646383 | J:314118
First Author: Feng P
Year: 2021
Journal: Theranostics
Title: The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis.
Volume: 11
Issue: 19
Pages: 9503-9518
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Publication
23183047 | J:194209
First Author: Finlay DK
Year: 2012
Journal: J Exp Med
Title: PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
Volume: 209
Issue: 13
Pages: 2441-53
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Publication
19605683 | J:150710
First Author: Chalhoub N
Year: 2009
Journal: Genes Dev
Title: Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains.
Volume: 23
Issue: 14
Pages: 1619-24
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Publication
32393635 | J:288808
First Author: Hosooka T
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B4 axis.
Volume: 117
Issue: 21
Pages: 11674-11684
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Publication
31527197 | J:280867
First Author: Ronkina N
Year: 2019
Journal: J Immunol
Title: The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3.
Volume: 203
Issue: 8
Pages: 2291-2300
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Publication
16243031 | J:102216
First Author: Bayascas JR
Year: 2005
Journal: Curr Biol
Title: Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.
Volume: 15
Issue: 20
Pages: 1839-46
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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