Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 308 out of 308 for Dgka

<< First < Previous | Next > Last >>

0.035s

Type

Details

Score

Protein Domain

IPR033718 | DAGK_prok

Type:

Family

Description:

This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of diacylglycerol to phosphatidic acid. Escherichia coli DAGK participates in the membrane-derived oligosaccharide cycle (MDO cycle) by recycling lipids to restore phosphatidylglycerols that were used up in the biosynthesis of MDOs. DAGK also recycles diacylglycerols that are produced during the biosynthesis of lipopolysaccharides (LPS) back to phospholipids. DAGK is not the main source of phosphatidic acid in de novo biosynthesis of glycerophospholipids. Escherichia coli DAGK has low activity as an undecaprenol kinase [, , ].

•

Publication

9422608 | -

First Author:	Chen P
Year:	1998
Journal:	J Bacteriol
Title:	Diacylglycerol kinase is involved in regulation of expression of the lantibiotic mutacin II of Streptococcus mutans.
Volume:	180
Issue:	1
Pages:	167-70

•

Publication

12923107 | -

First Author:	Amiteye S
Year:	2003
Journal:	J Bacteriol
Title:	Bacillus subtilis diacylglycerol kinase (DgkA) enhances efficient sporulation.
Volume:	185
Issue:	17
Pages:	5306-9

•

Publication

12450853 | -

First Author:	Yoshida A
Year:	2002
Journal:	Appl Environ Microbiol
Title:	Multiple Streptococcus mutans Genes Are Involved in Biofilm Formation.
Volume:	68
Issue:	12
Pages:	6283-91

•

Protein Domain

IPR033717 | UDPK

Type:

Family

Description:

This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate []. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to Gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries [, ]. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs [].

•

Publication

33593821 | J:305546

First Author:	Kovalenko A
Year:	2021
Journal:	Cancer Res
Title:	Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Volume:	81
Issue:	8
Pages:	2086-2100

•

Publication

29847571 | J:262844

First Author:	Millings EJ
Year:	2018
Journal:	PLoS One
Title:	ILDR2 has a negligible role in hepatic steatosis.
Volume:	13
Issue:	5
Pages:	e0197548

•

Publication

22224599 | -

First Author:	Van Horn WD
Year:	2012
Journal:	Annu Rev Biophys
Title:	Prokaryotic diacylglycerol kinase and undecaprenol kinase.
Volume:	41

Pages:	81-101

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do;jsessionid=340F22A44475F4F88CBF9092013C238A?searchTerm=Dgka&searchBag=&searchOffset=300

MouseMine

Search our database by keyword

Examples

Search results 301 to 308 out of 308 for Dgka

Categories

Hits by Pathway

Hits by Strain

Hits by Category