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Search results 1 to 100 out of 213 for Opa1

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Category: Publication
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Type Details Score
Publication
16839885 | J:116016
First Author: Frezza C
Year: 2006
Journal: Cell
Title: OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.
Volume: 126
Issue: 1
Pages: 177-89
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Publication
24616225 | J:215813
First Author: Anand R
Year: 2014
Journal: J Cell Biol
Title: The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.
Volume: 204
Issue: 6
Pages: 919-29
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Publication
23906536 | J:211383
First Author: Fülöp L
Year: 2013
Journal: Mol Cell Endocrinol
Title: Extramitochondrial OPA1 and adrenocortical function.
Volume: 381
Issue: 1-2
Pages: 70-9
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Publication
20652258 | J:162916
First Author: Moore BA
Year: 2010
Journal: Mamm Genome
Title: Mitochondrial retention of Opa1 is required for mouse embryogenesis.
Volume: 21
Issue: 7-8
Pages: 350-60
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Publication
26039449 | J:226126
First Author: Civiletto G
Year: 2015
Journal: Cell Metab
Title: Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models.
Volume: 21
Issue: 6
Pages: 845-54
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Publication
28636943 | J:347145
First Author: Del Dotto V
Year: 2017
Journal: Cell Rep
Title: OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions.
Volume: 19
Issue: 12
Pages: 2557-2571
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Publication
34133045 | J:309047
First Author: Robert P
Year: 2021
Journal: FASEB J
Title: Protective role of the mitochondrial fusion protein OPA1 in hypertension.
Volume: 35
Issue: 7
Pages: e21678
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Publication
19477917 | J:164489
First Author: Song Z
Year: 2009
Journal: Mol Biol Cell
Title: Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion.
Volume: 20
Issue: 15
Pages: 3525-32
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Publication
15509649 | J:94742
First Author: Cipolat S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: OPA1 requires mitofusin 1 to promote mitochondrial fusion.
Volume: 101
Issue: 45
Pages: 15927-32
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Publication
27587279 | J:237945
First Author: Barrera M
Year: 2016
Journal: FEBS Lett
Title: OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Volume: 590
Issue: 19
Pages: 3309-3322
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Publication
26785494 | J:229455
First Author: Wai T
Year: 2015
Journal: Science
Title: Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.
Volume: 350
Issue: 6265
Pages: aad0116
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Publication
33944779 | J:327582
   
First Author: Pereira RO
Year: 2021
Journal: Elife
Title: OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21.
Volume: 10
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Publication
31208084 | J:289420
 
First Author: Romanello V
Year: 2019
Journal: Cells
Title: Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles.
Volume: 8
Issue: 6
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Publication
34343501 | J:309736
First Author: Gómez-Valadés AG
Year: 2021
Journal: Cell Metab
Title: Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis.
Volume: 33
Issue: 9
Pages: 1820-1835.e9
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Publication
24703695 | J:213150
First Author: Mishra P
Year: 2014
Journal: Cell Metab
Title: Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Volume: 19
Issue: 4
Pages: 630-41
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Publication
33237841 | J:309720
First Author: Wang R
Year: 2021
Journal: Mol Biol Cell
Title: Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion.
Volume: 32
Issue: 2
Pages: 157-168
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Publication
28607005 | J:244364
First Author: Pereira RO
Year: 2017
Journal: EMBO J
Title: OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.
Volume: 36
Issue: 14
Pages: 2126-2145
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Publication
21551073 | J:183074
First Author: Zhang Z
Year: 2011
Journal: Mol Biol Cell
Title: The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells.
Volume: 22
Issue: 13
Pages: 2235-45
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Publication
28552492 | J:256769
First Author: Tezze C
Year: 2017
Journal: Cell Metab
Title: Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence.
Volume: 25
Issue: 6
Pages: 1374-1389.e6
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Publication
26783299 | J:230824
First Author: Korwitz A
Year: 2016
Journal: J Cell Biol
Title: Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
Volume: 212
Issue: 2
Pages: 157-66
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Publication
37874273 | J:346781
First Author: Yang Q
Year: 2023
Journal: FASEB J
Title: Loss of UCP2 causes mitochondrial fragmentation by OMA1-dependent proteolytic processing of OPA1 in podocytes.
Volume: 37
Issue: 11
Pages: e23265
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Publication
26218912 | J:230952
First Author: González-Menéndez I
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Influence of Opa1 Mutation on Survival and Function of Retinal Ganglion Cells.
Volume: 56
Issue: 8
Pages: 4835-45
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Publication
24671334 | J:210969
First Author: Xiao X
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury.
Volume: 306
Issue: 11
Pages: F1318-26
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Publication
19815013 | J:154865
First Author: Alavi MV
Year: 2009
Journal: Exp Neurol
Title: Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy.
Volume: 220
Issue: 2
Pages: 404-9
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Publication
34072974 | J:314507
 
First Author: Kim D
Year: 2021
Journal: Int J Mol Sci
Title: Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy.
Volume: 22
Issue: 11
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Publication
27468686 | J:315851
 
First Author: Kushnareva Y
Year: 2016
Journal: Cell Death Dis
Title: Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency.
Volume: 7
Pages: e2309
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Publication
37736113 | J:340796
 
First Author: Atamena D
Year: 2023
Journal: Front Mol Neurosci
Title: Genetic background modulates phenotypic expressivity in OPA1 mutated mice, relevance to DOA pathogenesis.
Volume: 16
Pages: 1241222
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Publication
22406748 | J:200812
First Author: Piquereau J
Year: 2012
Journal: Cardiovasc Res
Title: Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload.
Volume: 94
Issue: 3
Pages: 408-17
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Publication
27260406 | J:237307
First Author: Sarzi E
Year: 2016
Journal: Hum Mol Genet
Title: Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy.
Volume: 25
Issue: 12
Pages: 2539-2551
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Publication
12735796 | J:83833
 
First Author: Delettre C
Year: 2003
Journal: BMC Genet
Title: Gene structure and chromosomal localization of mouse Opa1 : its exclusion from the Bst locus.
Volume: 4
Pages: 8
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Publication
17003040 | J:117614
First Author: Duvezin-Caubet S
Year: 2006
Journal: J Biol Chem
Title: Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology.
Volume: 281
Issue: 49
Pages: 37972-9
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27861891 | J:239178
First Author: Moulis MF
Year: 2017
Journal: J Neurochem
Title: OPA1 haploinsufficiency induces a BNIP3-dependent decrease in mitophagy in neurons: relevance to Dominant Optic Atrophy.
Volume: 140
Issue: 3
Pages: 485-494
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Publication
36516772 | J:332395
First Author: Sessions DT
Year: 2022
Journal: Cell Rep
Title: Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD(+) regeneration in KRas-mutant lung adenocarcinoma.
Volume: 41
Issue: 11
Pages: 111818
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Publication
17314202 | J:154966
First Author: Alavi MV
Year: 2007
Journal: Brain
Title: A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.
Volume: 130
Issue: Pt 4
Pages: 1029-42
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Publication
20038678 | J:156874
First Author: Ehses S
Year: 2009
Journal: J Cell Biol
Title: Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1.
Volume: 187
Issue: 7
Pages: 1023-36
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28637784 | J:267446
First Author: Nan J
Year: 2017
Journal: Circ Res
Title: TNFR2 Stimulation Promotes Mitochondrial Fusion via Stat3- and NF-kB-Dependent Activation of OPA1 Expression.
Volume: 121
Issue: 4
Pages: 392-410
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Publication
22433842 | J:184716
First Author: Quirós PM
Year: 2012
Journal: EMBO J
Title: Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice.
Volume: 31
Issue: 9
Pages: 2117-33
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19234344 | J:154570
First Author: White KE
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: OPA1 deficiency associated with increased autophagy in retinal ganglion cells in a murine model of dominant optic atrophy.
Volume: 50
Issue: 6
Pages: 2567-71
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Publication
23714779 | J:199106
First Author: Santo-Domingo J
Year: 2013
Journal: EMBO J
Title: OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange.
Volume: 32
Issue: 13
Pages: 1927-40
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Publication
17428816 | J:121779
First Author: Davies VJ
Year: 2007
Journal: Hum Mol Genet
Title: Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function.
Volume: 16
Issue: 11
Pages: 1307-18
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Publication
25352671 | J:216764
First Author: Sood A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver.
Volume: 111
Issue: 45
Pages: 16017-22
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15161824 | J:92284
First Author: Aijaz S
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: Developmental expression profile of the optic atrophy gene product: OPA1 is not localized exclusively in the mammalian retinal ganglion cell layer.
Volume: 45
Issue: 6
Pages: 1667-73
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Publication
30143614 | J:266490
First Author: Quintana-Cabrera R
Year: 2018
Journal: Nat Commun
Title: The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function.
Volume: 9
Issue: 1
Pages: 3399
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Publication
26039448 | J:344143
First Author: Varanita T
Year: 2015
Journal: Cell Metab
Title: The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage.
Volume: 21
Issue: 6
Pages: 834-44
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Publication
24055366 | J:214492
First Author: Cogliati S
Year: 2013
Journal: Cell
Title: Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency.
Volume: 155
Issue: 1
Pages: 160-71
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Publication
11847212 | J:76355
First Author: Misaka T
Year: 2002
Journal: J Biol Chem
Title: Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology.
Volume: 277
Issue: 18
Pages: 15834-42
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32315597 | J:296538
First Author: Herkenne S
Year: 2020
Journal: Cell Metab
Title: Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1.
Volume: 31
Issue: 5
Pages: 987-1003.e8
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Publication
22658590 | J:199508
First Author: Wasilewski M
Year: 2012
Journal: Curr Biol
Title: Optic atrophy 1-dependent mitochondrial remodeling controls steroidogenesis in trophoblasts.
Volume: 22
Issue: 13
Pages: 1228-34
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27974214 | J:241706
First Author: Glytsou C
Year: 2016
Journal: Cell Rep
Title: Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control.
Volume: 17
Issue: 11
Pages: 3024-3034
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Publication
23250881 | J:237963
First Author: Sarzi E
Year: 2012
Journal: Brain
Title: The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse.
Volume: 135
Issue: Pt 12
Pages: 3599-613
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Publication
22902477 | J:198403
First Author: Belenguer P
Year: 2013
Journal: Biochim Biophys Acta
Title: The dynamin GTPase OPA1: more than mitochondria?
Volume: 1833
Issue: 1
Pages: 176-83
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21983901 | J:180083
First Author: Pidoux G
Year: 2011
Journal: EMBO J
Title: Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis.
Volume: 30
Issue: 21
Pages: 4371-86
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22579715 | J:188075
First Author: Sanjuán Szklarz LK
Year: 2012
Journal: Biochim Biophys Acta
Title: The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock.
Volume: 1817
Issue: 10
Pages: 1886-93
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28746876 | J:254859
First Author: Huang G
Year: 2017
Journal: Cell Rep
Title: WBSCR16 Is a Guanine Nucleotide Exchange Factor Important for Mitochondrial Fusion.
Volume: 20
Issue: 4
Pages: 923-934
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24550258 | J:208034
First Author: Baker MJ
Year: 2014
Journal: EMBO J
Title: Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics.
Volume: 33
Issue: 6
Pages: 578-93
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Publication
21803037 | J:189276
First Author: Barnard AR
Year: 2011
Journal: Exp Eye Res
Title: Specific deficits in visual electrophysiology in a mouse model of dominant optic atrophy.
Volume: 93
Issue: 5
Pages: 771-7
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32571921 | J:291523
First Author: Meschede IP
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1.
Volume: 117
Issue: 27
Pages: 15684-15693
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Publication
32756920 | J:293812
First Author: Kim D
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy.
Volume: 61
Issue: 10
Pages: 10
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Publication
24042504 | J:215842
First Author: Caffin F
Year: 2013
Journal: J Physiol
Title: Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice.
Volume: 591
Issue: 23
Pages: 6017-37
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Publication
19834041 | J:160417
First Author: Heiduschka P
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Electrophysiological and histologic assessment of retinal ganglion cell fate in a mouse model for OPA1-associated autosomal dominant optic atrophy.
Volume: 51
Issue: 3
Pages: 1424-31
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22158479 | J:202211
 
First Author: Nguyen D
Year: 2011
Journal: Cell Death Dis
Title: A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics.
Volume: 2
Pages: e240
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27723783 | J:251340
First Author: Le Page S
Year: 2016
Journal: PLoS One
Title: Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model.
Volume: 11
Issue: 10
Pages: e0164066
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28159969 | J:257139
First Author: Chao de la Barca JM
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Targeted Metabolomics Reveals Early Dominant Optic Atrophy Signature in Optic Nerves of Opa1delTTAG/+ Mice.
Volume: 58
Issue: 2
Pages: 812-820
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18200046 | J:131413
First Author: Twig G
Year: 2008
Journal: EMBO J
Title: Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Volume: 27
Issue: 2
Pages: 433-46
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21346246 | J:172413
First Author: Makino A
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes.
Volume: 300
Issue: 6
Pages: R1296-302
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22858546 | J:205546
First Author: Ramonet D
Year: 2013
Journal: Cell Death Differ
Title: Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.
Volume: 20
Issue: 1
Pages: 77-85
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25298396 | J:216587
First Author: Patten DA
Year: 2014
Journal: EMBO J
Title: OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.
Volume: 33
Issue: 22
Pages: 2676-91
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30068998 | J:323712
First Author: Bocca C
Year: 2018
Journal: Sci Rep
Title: The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency.
Volume: 8
Issue: 1
Pages: 11528
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Publication
19360003 | J:149906
First Author: Tondera D
Year: 2009
Journal: EMBO J
Title: SLP-2 is required for stress-induced mitochondrial hyperfusion.
Volume: 28
Issue: 11
Pages: 1589-600
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23453807 | J:198144
First Author: Müller-Rischart AK
Year: 2013
Journal: Mol Cell
Title: The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.
Volume: 49
Issue: 5
Pages: 908-21
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26024391 | J:259867
First Author: Laforge M
Year: 2016
Journal: Cell Death Differ
Title: NF-κB pathway controls mitochondrial dynamics.
Volume: 23
Issue: 1
Pages: 89-98
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20064504 | J:158842
First Author: Kieper N
Year: 2010
Journal: Exp Cell Res
Title: Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.
Volume: 316
Issue: 7
Pages: 1213-24
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26820596 | J:231368
 
First Author: Smith TG
Year: 2016
Journal: Neuroscience
Title: A randomized, placebo-controlled trial of the benzoquinone idebenone in a mouse model of OPA1-related dominant optic atrophy reveals a limited therapeutic effect on retinal ganglion cell dendropathy and visual function.
Volume: 319
Pages: 92-106
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19443720 | J:154544
First Author: Yu-Wai-Man P
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Secondary mtDNA defects do not cause optic nerve dysfunction in a mouse model of dominant optic atrophy.
Volume: 50
Issue: 10
Pages: 4561-6
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23409176 | J:197201
First Author: Perganta G
Year: 2013
Journal: PLoS One
Title: Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy.
Volume: 8
Issue: 2
Pages: e56350
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16839884 | J:116017
First Author: Cipolat S
Year: 2006
Journal: Cell
Title: Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.
Volume: 126
Issue: 1
Pages: 163-75
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18691924 | J:139566
First Author: Yamaguchi R
Year: 2008
Journal: Mol Cell
Title: Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
Volume: 31
Issue: 4
Pages: 557-69
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15899901 | J:281198
First Author: Chen H
Year: 2005
Journal: J Biol Chem
Title: Disruption of fusion results in mitochondrial heterogeneity and dysfunction.
Volume: 280
Issue: 28
Pages: 26185-92
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21642619 | J:181410
First Author: Ganapathy PS
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells.
Volume: 52
Issue: 8
Pages: 5551-8
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Publication
35222801 | J:321633
 
First Author: Zhu P
Year: 2022
Journal: Oxid Med Cell Longev
Title: NR4A1 Promotes LPS-Induced Acute Lung Injury through Inhibition of Opa1-Mediated Mitochondrial Fusion and Activation of PGAM5-Related Necroptosis.
Volume: 2022
Pages: 6638244
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21081504 | J:173140
First Author: Darshi M
Year: 2011
Journal: J Biol Chem
Title: ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function.
Volume: 286
Issue: 4
Pages: 2918-32
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Publication
36754021 | J:333326
First Author: Suh J
Year: 2023
Journal: Cell Metab
Title: Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis.
Volume: 35
Issue: 2
Pages: 345-360.e7
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15755804 | J:98216
First Author: García-García MJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Analysis of mouse embryonic patterning and morphogenesis by forward genetics.
Volume: 102
Issue: 17
Pages: 5913-9
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28591639 | J:256762
First Author: Ramírez S
Year: 2017
Journal: Cell Metab
Title: Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.
Volume: 25
Issue: 6
Pages: 1390-1399.e6
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Publication
34669477 | J:313690
First Author: Gabriel BM
Year: 2021
Journal: Sci Adv
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