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Search results 201 to 257 out of 257 for Tpm2

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0.024s
Type Details Score
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Drees B
Year: 1995
Journal: J Cell Biol
Title: Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions.
Volume: 128
Issue: 3
Pages: 383-92
DO Term
DO Term
Allele
Name: transgene insertion 1, David F Wieczorek
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Schevzov G
Year: 2008
Journal: J Biol Chem
Title: Divergent regulation of the sarcomere and the cytoskeleton.
Volume: 283
Issue: 1
Pages: 275-83
Publication
First Author: Mamidi R
Year: 2013
Journal: J Physiol
Title: Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function.
Volume: 591
Issue: 5
Pages: 1217-34
Publication
First Author: MacGowan GA
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Compensatory changes in Ca(2+) and myocardial O(2) consumption in beta-tropomyosin transgenic hearts.
Volume: 281
Issue: 6
Pages: H2539-48
Publication
First Author: Muthuchamy M
Year: 1998
Journal: J Mol Cell Cardiol
Title: Beta-tropomyosin overexpression induces severe cardiac abnormalities.
Volume: 30
Issue: 8
Pages: 1545-57
Publication
First Author: Sussman MA
Year: 1998
Journal: Science
Title: Prevention of cardiac hypertrophy in mice by calcineurin inhibition.
Volume: 281
Issue: 5383
Pages: 1690-3
Protein
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Publication
First Author: MacLeod AR
Year: 1987
Journal: Bioessays
Title: Genetic origin of diversity of human cytoskeletal tropomyosins.
Volume: 6
Issue: 5
Pages: 208-12
Publication
First Author: Lewis WG
Year: 1980
Journal: J Biol Chem
Title: The amino acid sequence of rabbit cardiac tropomyosin.
Volume: 255
Issue: 14
Pages: 6854-9
Publication
First Author: Wolska BM
Year: 2003
Journal: Pflugers Arch
Title: The role of tropomyosin in the regulation of myocardial contraction and relaxation.
Volume: 446
Issue: 1
Pages: 1-8
Protein Domain
Type: Family
Description: Tropomyosins [], are a family of closely related proteins present in muscle and non-muscle cells. In striated muscle, tropomyosin mediate the interactions between the troponin complex and actin so as to regulate muscle contraction []. The role of tropomyosin in smooth muscle and non-muscle tissues is not clear. Tropomyosin is an α-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites []. There are multiple cell-specific isoforms, created by differential splicing of the messenger RNA from one gene, but the proportions of the isoforms vary between different cell types. Muscle isoforms of tropomyosin are characterised by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.This entry represents tropomyosin (Tmp) 1, 2 and 3. Within the yeast Tmp1 and Tmp2, biochemical and sequence analyses indicate that Tpm2 spans four actin monomers along a filament, whereas Tpm1 spans five. Despite its shorter length, Tpm2 can compete with Tpm1 for binding to F-actin. Over-expression of Tpm2 in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis [].
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7