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Search results 101 to 173 out of 173 for Vps25

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Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459980
Specimen Label: TCP_2459980
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459983
Specimen Label: TCP_2459983
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459984
Specimen Label: TCP_2459984
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459981
Specimen Label: TCP_2459981
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459982
Specimen Label: TCP_2459982
Detected: true
Specimen Num: 8
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•
GXD Expression
GXD Expression
Probe: MGI:7528979
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7529370
Age: embryonic day 9.5
Image: 5D
Note: Expression was enriched in neuroepithelium.
Specimen Label: 5D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7528979
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529370
Age: embryonic day 10.5
Image: 6D
Note: Expression was enriched in neuroepithelium.
Specimen Label: 6D
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Ubiquitous
Stage: TS13
Assay Id: MGI:7529107
Age: embryonic day 8.25-8.75
Image: 1A
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Ubiquitous
Stage: TS15
Assay Id: MGI:7529107
Age: embryonic day 9.5
Image: 1B
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Ubiquitous
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Ubiquitous
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Ubiquitous
Stage: TS19
Assay Id: MGI:7529107
Age: embryonic day 11.5
Image: 3A
Specimen Label: 3A
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Ubiquitous
Stage: TS19
Assay Id: MGI:7529107
Age: embryonic day 11.5
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:7529145
Age: embryonic day 8.5
Image: 4E E8.5 left
Specimen Label: 4E E8.5 left
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:7529145
Age: embryonic day 8.5
Image: 4E E8.5 right
Specimen Label: 4E E8.5 right
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529145
Age: embryonic day 10.5
Image: 4F
Note: Expression was enriched in surface cephalic epithelium.
Specimen Label: 4F
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7528979
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7529370
Age: embryonic day 9.5
Image: 5D
Note: Expression was enriched in surface cephalic epithelium.
Specimen Label: 5D
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:7528979
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529370
Age: embryonic day 10.5
Image: 6D
Note: Expression was enriched in surface cephalic epithelium.
Specimen Label: 6D
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2B
Note: Expression was highest in the most anterior edge of the mandibular process.
Specimen Label: 2B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3273213
Pattern: Widespread
Stage: TS13
Assay Id: MGI:7529107
Age: embryonic day 8.25-8.75
Image: 1A
Note: High enriched expression was detected in the neural folds along the entirety of the dorsal anterior-posterior axis.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1627215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7529107
Age: embryonic day 9.5
Image: 1B
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2B
Note: Expression was highest in the posterior edge with lower uniform expression seen throughout the rest of the arch.
Specimen Label: 2B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1627219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7529107
Age: embryonic day 11.5
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2A
Note: Expression in the emerging hindlimb is most apparent at the most distal tip with reduced expression proximally.
Specimen Label: 2A
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7529107
Age: embryonic day 11.5
Image: 3A
Note: Expression appeared highest distally, with attenuated signal at the core of the limb buds.
Specimen Label: 3A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459985
Specimen Label: TCP_2459985
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691064
Age: postnatal adult
Image: TCP_2459986
Specimen Label: TCP_2459986
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1680517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2B
Note: Expression was highest at the rim of the nasal pit perimeter.
Specimen Label: 2B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1680519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7529107
Age: embryonic day 11.5
Image: 3B
Note: Expression was highest in the lateral edges.
Specimen Label: 3B
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529107
Age: embryonic day 10.5
Image: 2B
Note: Expression was highest in the most posterior edge of the maxillary process.
Specimen Label: 2B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7528816
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7529107
Age: embryonic day 11.5
Image: 3B
Note: Expression was highest in the lateral edges.
Specimen Label: 3B
Detected: true
Specimen Num: 6
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Publication
9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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Publication
- | J:29126
     
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
15579210 | -
First Author: Wernimont AK
Year: 2004
Journal: BMC Struct Biol
Title: Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II.
Volume: 4
Issue: 1
Pages: 10
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Protein Domain
IPR008570 | ESCRT-II_cplx_Vps25-sub
Type: Family
Description: This entry represents the Vps25 subunit (vacuolar protein sorting-associated protein 25) of the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate efficient sorting of ubiquitinated transmembrane receptors to lysosomes via multivesicular bodies (MVBs) []. ESCRT-II recruits the transport machinery for protein sorting at MVB []. In addition, the human ESCRT-II has been shown to form a complex with RNA polymerase II elongation factor ELL in order to exert transcriptional control activity. ESCRT-II transiently associates with the endosomal membrane and thereby initiates the formation of ESCRT-III, a membrane-associated protein complex that functions immediately downstream of ESCRT-II during sorting of MVB cargo. ESCRT-II in turn functions downstream of ESCRT-I, a protein complex that binds to ubiquitinated endosomal cargo [].ESCRT-II is a trilobal complex composed of two copies of vps25, one copy of vps22 and the C-terminal region of vps36. The crystal structure of vps25 revealed two winged-helix domains, the N-terminal domain of vps25 interacting with vps22 and vps35 [].
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Protein
Q9CQ80
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: false
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Protein Domain
IPR014041 | ESCRT-II_cplx_Vps25-sub_N
Type: Homologous_superfamily
Description: This superfamily represents the N-terminal winged helix domain of the vps25 subunit (vacuolar protein sorting-associated protein 25) of the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate efficient sorting of ubiquitinated transmembrane receptors to lysosomes via multivesicular bodies (MVBs) []. ESCRT-II recruits the transport machinery for protein sorting at MVB []. In addition, the human ESCRT-II has been shown to form a complex with RNA polymerase II elongation factor ELL in order to exert transcriptional control activity. ESCRT-II transiently associates with the endosomal membrane and thereby initiates the formation of ESCRT-III, a membrane-associated protein complex that functions immediately downstream of ESCRT-II during sorting of MVB cargo. ESCRT-II in turn functions downstream of ESCRT-I, a protein complex that binds to ubiquitinated endosomal cargo [].ESCRT-II is a trilobal complex composed of two copies of vps25, one copy of vps22 and the C-terminal region of vps36. The crystal structure of vps25 revealed two winged-helix domains, the N-terminal domain of vps25 interacting with vps22 and vps35 [].
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Publication
12194858 | -
First Author: Babst M
Year: 2002
Journal: Dev Cell
Title: Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.
Volume: 3
Issue: 2
Pages: 283-9
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Publication
15469844 | -
First Author: Teo H
Year: 2004
Journal: Dev Cell
Title: ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.
Volume: 7
Issue: 4
Pages: 559-69
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Protein
Q9CQ80-2
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: false
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Publication
17215868 | -
First Author: Gill DJ
Year: 2007
Journal: EMBO J
Title: Structural insight into the ESCRT-I/-II link and its role in MVB trafficking.
Volume: 26
Issue: 2
Pages: 600-12
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