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Search results 301 to 397 out of 397 for Notch3

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Category: Publication
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Type Details Score
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30038265 | J:267436
First Author: Ferrandino F
Year: 2018
Journal: Oncogene
Title: Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation.
Volume: 37
Issue: 49
Pages: 6285-6298
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22120716 | J:187796
First Author: Palermo R
Year: 2012
Journal: Oncogene
Title: Acetylation controls Notch3 stability and function in T-cell leukemia.
Volume: 31
Issue: 33
Pages: 3807-17
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29463793 | J:262970
First Author: Idowu J
Year: 2018
Journal: Sci Rep
Title: Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease.
Volume: 8
Issue: 1
Pages: 3340
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26876201 | J:230813
First Author: Franciosa G
Year: 2016
Journal: Oncogene
Title: Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.
Volume: 35
Issue: 36
Pages: 4741-51
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Publication
20801121 | J:178669
First Author: Ohashi S
Year: 2010
Journal: Gastroenterology
Title: NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.
Volume: 139
Issue: 6
Pages: 2113-23
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Publication
21245095 | J:169308
First Author: Pierfelice TJ
Year: 2011
Journal: Cancer Res
Title: Notch3 activation promotes invasive glioma formation in a tissue site-specific manner.
Volume: 71
Issue: 3
Pages: 1115-25
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12507916 | J:129831
First Author: Ruchoux MM
Year: 2003
Journal: Am J Pathol
Title: Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Volume: 162
Issue: 1
Pages: 329-42
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Publication
29170450 | J:255959
First Author: Natsuizaka M
Year: 2017
Journal: Nat Commun
Title: Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.
Volume: 8
Issue: 1
Pages: 1758
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Publication
23845442 | J:199306
First Author: Zheng Y
Year: 2013
Journal: Cancer Cell
Title: A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal.
Volume: 24
Issue: 1
Pages: 59-74
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Publication
19461123 | J:149531
First Author: Campese AF
Year: 2009
Journal: Int Immunol
Title: Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells.
Volume: 21
Issue: 6
Pages: 727-43
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11891328 | J:75270
First Author: Bellavia D
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
Volume: 99
Issue: 6
Pages: 3788-93
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Publication
19150886 | -
First Author: Liu H
Year: 2009
Journal: Circ Res
Title: NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1.
Volume: 104
Issue: 4
Pages: 466-75
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20071773 | J:156682
First Author: Joutel A
Year: 2010
Journal: J Clin Invest
Title: Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease.
Volume: 120
Issue: 2
Pages: 433-45
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25646445 | J:220006
First Author: Dabertrand F
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.
Volume: 112
Issue: 7
Pages: E796-805
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Publication
28345617 | J:329829
 
First Author: Klein C
Year: 2017
Journal: Sci Rep
Title: Stimulation of adult hippocampal neurogenesis by physical exercise and enriched environment is disturbed in a CADASIL mouse model.
Volume: 7
Pages: 45372
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34483880 | J:312898
 
First Author: Rosehart AC
Year: 2021
Journal: Front Aging Neurosci
Title: Prostaglandin E2 Dilates Intracerebral Arterioles When Applied to Capillaries: Implications for Small Vessel Diseases.
Volume: 13
Pages: 695965
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25251607 | J:218448
 
First Author: Liu XY
Year: 2015
Journal: Neurobiol Dis
Title: Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL.
Volume: 73
Pages: 189-203
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15817893 | J:133984
First Author: Lacombe P
Year: 2005
Journal: Stroke
Title: Impaired cerebral vasoreactivity in a transgenic mouse model of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy arteriopathy.
Volume: 36
Issue: 5
Pages: 1053-8
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15569862 | J:134742
First Author: Dubroca C
Year: 2005
Journal: Stroke
Title: Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy.
Volume: 36
Issue: 1
Pages: 113-7
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32852523 | J:298816
 
First Author: Koch U
Year: 2020
Journal: J Exp Med
Title: A third Notch in colorectal cancer progression and metastasis.
Volume: 217
Issue: 10
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27476853 | J:235433
   
First Author: Capone C
Year: 2016
Journal: Elife
Title: Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics.
Volume: 5
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16530044 | -
First Author: Nam Y
Year: 2006
Journal: Cell
Title: Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Volume: 124
Issue: 5
Pages: 973-83
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18758478 | -
First Author: Kovall RA
Year: 2008
Journal: Oncogene
Title: More complicated than it looks: assembly of Notch pathway transcription complexes.
Volume: 27
Issue: 38
Pages: 5099-109
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18758483 | J:141198
First Author: McElhinny AS
Year: 2008
Journal: Oncogene
Title: Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways.
Volume: 27
Issue: 38
Pages: 5138-47
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16510869 | J:106711
First Author: Shen H
Year: 2006
Journal: Genes Dev
Title: The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis.
Volume: 20
Issue: 6
Pages: 675-88
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17317671 | -
First Author: Zhao Y
Year: 2007
Journal: J Biol Chem
Title: The notch regulator MAML1 interacts with p53 and functions as a coactivator.
Volume: 282
Issue: 16
Pages: 11969-81
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17875709 | -
First Author: Alves-Guerra MC
Year: 2007
Journal: Cancer Res
Title: Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival.
Volume: 67
Issue: 18
Pages: 8690-8
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16880534 | -
First Author: Chiang MY
Year: 2006
Journal: Mol Cell Biol
Title: Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1.
Volume: 26
Issue: 16
Pages: 6261-71
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17699740 | J:149110
First Author: Wu L
Year: 2007
Journal: Blood
Title: The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development.
Volume: 110
Issue: 10
Pages: 3618-23
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Publication
15961999 | -
First Author: Wu L
Year: 2005
Journal: EMBO J
Title: Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation.
Volume: 24
Issue: 13
Pages: 2391-402
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15546612 | -
First Author: Fryer CJ
Year: 2004
Journal: Mol Cell
Title: Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.
Volume: 16
Issue: 4
Pages: 509-20
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12370315 | J:79612
First Author: Wu L
Year: 2002
Journal: Mol Cell Biol
Title: Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.
Volume: 22
Issue: 21
Pages: 7688-700
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Publication
15592506 | J:96010
First Author: Felli MP
Year: 2005
Journal: Oncogene
Title: PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia.
Volume: 24
Issue: 6
Pages: 992-1000
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Publication
34590699 | J:312438
 
First Author: Cameron B
Year: 2021
Journal: Biol Open
Title: Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway.
Volume: 10
Issue: 9
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14566327 | J:86506
First Author: Talora C
Year: 2003
Journal: EMBO Rep
Title: Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma.
Volume: 4
Issue: 11
Pages: 1067-72
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Publication
17081781 | J:116137
First Author: Kared H
Year: 2006
Journal: Immunity
Title: Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling.
Volume: 25
Issue: 5
Pages: 823-34
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23277114 | J:194992
First Author: Zhu MY
Year: 2013
Journal: Gene Expr Patterns
Title: The expression of NOTCH2, HES1 and SOX9 during mouse retinal development.
Volume: 13
Issue: 3-4
Pages: 78-83
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23684539 | J:199317
First Author: Gu B
Year: 2013
Journal: Cell Stem Cell
Title: Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells.
Volume: 13
Issue: 1
Pages: 48-61
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29230914 | J:261529
First Author: Low S
Year: 2018
Journal: Stem Cells
Title: Delta-Like 4 Activates Notch 3 to Regulate Self-Renewal in Skeletal Muscle Stem Cells.
Volume: 36
Issue: 3
Pages: 458-466
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Publication
33440163 | J:320834
First Author: Pang J
Year: 2021
Journal: Cell Rep
Title: NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression.
Volume: 34
Issue: 2
Pages: 108603
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24749067 | J:329722
First Author: Gopinath SD
Year: 2014
Journal: Stem Cell Reports
Title: FOXO3 promotes quiescence in adult muscle stem cells during the process of self-renewal.
Volume: 2
Issue: 4
Pages: 414-26
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Publication
12050117 | -
First Author: Fryer CJ
Year: 2002
Journal: Genes Dev
Title: Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.
Volume: 16
Issue: 11
Pages: 1397-411
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33875602 | J:325198
 
First Author: Dabertrand F
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity.
Volume: 118
Issue: 17
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Publication
35202003 | J:323882
 
First Author: Oka F
Year: 2022
Journal: J Clin Invest
Title: CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis.
Volume: 132
Issue: 8
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30226866 | J:266199
First Author: Huang S
Year: 2018
Journal: PLoS Biol
Title: Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.
Volume: 16
Issue: 9
Pages: e2005233
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21118965 | J:166963
First Author: Sullivan JP
Year: 2010
Journal: Cancer Res
Title: Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
Volume: 70
Issue: 23
Pages: 9937-48
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37318881 | J:339975
 
First Author: Sugiura K
Year: 2023
Journal: JCI Insight
Title: LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3.
Volume: 8
Issue: 14
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28266128 | J:271834
First Author: Wang S
Year: 2017
Journal: J Cell Mol Med
Title: Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice.
Volume: 21
Issue: 9
Pages: 1967-1978
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27613846 | J:274430
First Author: Wang S
Year: 2016
Journal: Oncotarget
Title: Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling.
Volume: 7
Issue: 37
Pages: 58848-58861
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23630352 | J:204776
First Author: Gopisetty A
Year: 2013
Journal: J Immunol
Title: OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells.
Volume: 190
Issue: 11
Pages: 5516-25
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31796853 | J:297963
First Author: Klose R
Year: 2019
Journal: Sci Rep
Title: Loss of the serine protease HTRA1 impairs smooth muscle cells maturation.
Volume: 9
Issue: 1
Pages: 18224
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28752390 | J:263753
First Author: Cuervo H
Year: 2017
Journal: Angiogenesis
Title: PDGFRβ-P2A-CreERT2 mice: a genetic tool to target pericytes in angiogenesis.
Volume: 20
Issue: 4
Pages: 655-662
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21743488 | J:181067
First Author: Pradeep CR
Year: 2012
Journal: Oncogene
Title: Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling.
Volume: 31
Issue: 7
Pages: 907-17
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21994468 | J:205398
First Author: Osanyingbemi-Obidi J
Year: 2011
Journal: Mol Cancer Res
Title: Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo.
Volume: 9
Issue: 12
Pages: 1746-54
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Publication
23530123 | J:198219
First Author: Van de Walle I
Year: 2013
Journal: J Exp Med
Title: Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.
Volume: 210
Issue: 4
Pages: 683-97
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Publication
26868537 | J:263576
 
First Author: Zeng H
Year: 2016
Journal: Sci Rep
Title: LPS causes pericyte loss and microvascular dysfunction via disruption of Sirt3/angiopoietins/Tie-2 and HIF-2α/Notch3 pathways.
Volume: 6
Pages: 20931
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Publication
30502484 | J:282276
 
First Author: Papadakos KS
Year: 2019
Journal: Matrix Biol
Title: Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.
Volume: 81
Pages: 107-121
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31704879 | J:282061
First Author: Kumar P
Year: 2019
Journal: J Immunol
Title: OX40L-JAG1-Induced Expansion of Lineage-Stable Regulatory T Cells Involves Noncanonical NF-κB Signaling.
Volume: 203
Issue: 12
Pages: 3225-3236
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36645109 | J:338757
First Author: Li X
Year: 2023
Journal: FASEB J
Title: Deficiency of thrombospondin-2 alleviates intimal hyperplasia in mice by modulating vascular smooth muscle cell proliferation and migration.
Volume: 37
Issue: 2
Pages: e22743
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19688092 | J:152461
First Author: Dudley DD
Year: 2009
Journal: PLoS One
Title: Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.
Volume: 4
Issue: 8
Pages: e6678
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Publication
20804727 | J:165587
First Author: Bargo S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeats.
Volume: 400
Issue: 4
Pages: 606-12
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Publication
29206900 | J:261096
First Author: Zhang C
Year: 2018
Journal: Cardiovasc Res
Title: Cbx3 inhibits vascular smooth muscle cell proliferation, migration, and neointima formation.
Volume: 114
Issue: 3
Pages: 443-455
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26279302 | J:309335
First Author: Zhang S
Year: 2016
Journal: Oncogene
Title: Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
Volume: 35
Issue: 19
Pages: 2485-95
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35792302 | J:341865
 
First Author: Breikaa RM
Year: 2022
Journal: Vascul Pharmacol
Title: Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes.
Volume: 145
Pages: 107087
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Publication
24039710 | J:225185
First Author: Li L
Year: 2013
Journal: PLoS One
Title: Myocardial injection of apelin-overexpressing bone marrow cells improves cardiac repair via upregulation of Sirt3 after myocardial infarction.
Volume: 8
Issue: 9
Pages: e71041
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Publication
32325086 | J:314302
First Author: Kunze B
Year: 2020
Journal: Gastroenterology
Title: Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma.
Volume: 159
Issue: 2
Pages: 575-590
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Publication
36107978 | J:329263
First Author: Alexander GM
Year: 2022
Journal: PLoS One
Title: Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease.
Volume: 17
Issue: 9
Pages: e0274615
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Publication
29162437 | J:277897
First Author: Andersson ER
Year: 2018
Journal: Gastroenterology
Title: Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.
Volume: 154
Issue: 4
Pages: 1080-1095
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First Author: Kopan R
Year: 2009
Journal: Cell
Title: The canonical Notch signaling pathway: unfolding the activation mechanism.
Volume: 137
Issue: 2
Pages: 216-33
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12354787 | J:94943
First Author: Hartmann D
Year: 2002
Journal: Hum Mol Genet
Title: The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.
Volume: 11
Issue: 21
Pages: 2615-24
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11101851 | -
First Author: Wu L
Year: 2000
Journal: Nat Genet
Title: MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.
Volume: 26
Issue: 4
Pages: 484-9
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First Author: Gridley T
Year: 2003
Journal: Hum Mol Genet
Title: Notch signaling and inherited disease syndromes.
Volume: 12 Spec No 1
Pages: R9-13
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First Author: Louvi A
Year: 2006
Journal: Nat Rev Neurosci
Title: Notch signalling in vertebrate neural development.
Volume: 7
Issue: 2
Pages: 93-102
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10206645 | J:54336
First Author: De Strooper B
Year: 1999
Journal: Nature
Title: A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
Volume: 398
Issue: 6727
Pages: 518-22
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First Author: Artavanis-Tsakonas S
Year: 1999
Journal: Science
Title: Notch signaling: cell fate control and signal integration in development.
Volume: 284
Issue: 5415
Pages: 770-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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