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Search results 1 to 100 out of 144 for Otof

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Publication
First Author: Yasunaga S
Year: 2000
Journal: Am J Hum Genet
Title: OTOF encodes multiple long and short isoforms: genetic evidence that the long ones underlie recessive deafness DFNB9.
Volume: 67
Issue: 3
Pages: 591-600
GXD Expression      
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191003
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Otof
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191003
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Otof
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191003
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Otof
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191003
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Otof
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191003
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Otof
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191003
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Otof
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191003
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Otof
Detected: true
Specimen Num: 7
Publication      
First Author: Akil O
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model.
Publication
First Author: Strenzke N
Year: 2016
Journal: EMBO J
Title: Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants.
Volume: 35
Issue: 23
Pages: 2519-2535
Publication  
First Author: Stalmann U
Year: 2021
Journal: Front Cell Neurosci
Title: Otoferlin Is Required for Proper Synapse Maturation and for Maintenance of Inner and Outer Hair Cells in Mouse Models for DFNB9.
Volume: 15
Pages: 677543
Publication  
First Author: Tsuzuki N
Year: 2023
Journal: Neurosci Lett
Title: Apoptosis of type I spiral ganglion neuron cells in Otof-mutant mice.
Volume: 803
Pages: 137178
Publication  
First Author: Chakrabarti R
Year: 2018
Journal: EMBO Rep
Title: Vesicle sub-pool organization at inner hair cell ribbon synapses.
Volume: 19
Issue: 11
Publication  
First Author: Takago H
Year: 2018
Journal: Front Mol Neurosci
Title: Disruption of Otoferlin Alters the Mode of Exocytosis at the Mouse Inner Hair Cell Ribbon Synapse.
Volume: 11
Pages: 492
Publication
First Author: Tertrais M
Year: 2019
Journal: J Neurosci
Title: Viral Transfer of Mini-Otoferlins Partially Restores the Fast Component of Exocytosis and Uncovers Ultrafast Endocytosis in Auditory Hair Cells of Otoferlin Knock-Out Mice.
Volume: 39
Issue: 18
Pages: 3394-3411
Publication
First Author: Longo-Guess C
Year: 2007
Journal: Hear Res
Title: A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.
Volume: 234
Issue: 1-2
Pages: 21-8
Publication
First Author: Reisinger E
Year: 2011
Journal: J Neurosci
Title: Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.
Volume: 31
Issue: 13
Pages: 4886-95
Publication
First Author: Ramakrishnan NA
Year: 2009
Journal: J Biol Chem
Title: Direct interaction of otoferlin with syntaxin 1A, SNAP-25, and the L-type voltage-gated calcium channel Cav1.3.
Volume: 284
Issue: 3
Pages: 1364-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Beurg M
Year: 2008
Journal: J Neurosci
Title: Calcium- and otoferlin-dependent exocytosis by immature outer hair cells.
Volume: 28
Issue: 8
Pages: 1798-803
Publication      
First Author: Chen H
Year: 2023
Journal: Protein Cell
Title: Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing.
Publication
First Author: Hintze A
Year: 2024
Journal: iScience
Title: Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus.
Volume: 27
Issue: 1
Pages: 108700
Publication    
First Author: Michalski N
Year: 2017
Journal: Elife
Title: Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
Volume: 6
Publication
First Author: Kirst C
Year: 2020
Journal: Cell
Title: Mapping the Fine-Scale Organization and Plasticity of the Brain Vasculature.
Volume: 180
Issue: 4
Pages: 780-795.e25
Publication
First Author: Pangrsic T
Year: 2010
Journal: Nat Neurosci
Title: Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.
Volume: 13
Issue: 7
Pages: 869-76
Publication  
First Author: Chen H
Year: 2023
Journal: Front Mol Neurosci
Title: Probing the role of the C(2)F domain of otoferlin.
Volume: 16
Pages: 1299509
Publication
First Author: Wright S
Year: 2014
Journal: J Neurophysiol
Title: Synaptic transmission between end bulbs of Held and bushy cells in the cochlear nucleus of mice with a mutation in Otoferlin.
Volume: 112
Issue: 12
Pages: 3173-88
Publication
First Author: Dulon D
Year: 2009
Journal: J Neurosci
Title: Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses.
Volume: 29
Issue: 34
Pages: 10474-87
Publication
First Author: Revelo NH
Year: 2014
Journal: J Cell Biol
Title: A new probe for super-resolution imaging of membranes elucidates trafficking pathways.
Volume: 205
Issue: 4
Pages: 591-606
Publication
First Author: Vincent PFY
Year: 2018
Journal: Cell Rep
Title: Clustered Ca2+ Channels Are Blocked by Synaptic Vesicle Proton Release at Mammalian Auditory Ribbon Synapses.
Volume: 25
Issue: 12
Pages: 3451-3464.e3
Publication
First Author: Vincent PF
Year: 2014
Journal: J Neurosci
Title: Exocytotic machineries of vestibular type I and cochlear ribbon synapses display similar intrinsic otoferlin-dependent Ca2+ sensitivity but a different coupling to Ca2+ channels.
Volume: 34
Issue: 33
Pages: 10853-69
Publication
First Author: Ramakrishnan NA
Year: 2014
Journal: J Biol Chem
Title: Calcium regulates molecular interactions of otoferlin with soluble NSF attachment protein receptor (SNARE) proteins required for hair cell exocytosis.
Volume: 289
Issue: 13
Pages: 8750-66
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_07
Specimen Label: euxassay_007676_07
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_08
Specimen Label: euxassay_007676_08
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_10
Specimen Label: euxassay_007676_10
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_11
Specimen Label: euxassay_007676_11
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_13
Specimen Label: euxassay_007676_13
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_14
Specimen Label: euxassay_007676_14
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_15
Specimen Label: euxassay_007676_15
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_16
Specimen Label: euxassay_007676_16
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_17
Specimen Label: euxassay_007676_17
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_18
Specimen Label: euxassay_007676_18
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_04
Specimen Label: euxassay_007676_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_05
Specimen Label: euxassay_007676_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_19
Specimen Label: euxassay_007676_19
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_20
Specimen Label: euxassay_007676_20
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_21
Specimen Label: euxassay_007676_21
Detected: true
Specimen Num: 15
Publication
First Author: Noh J
Year: 2010
Journal: Nat Neurosci
Title: Glutamate co-release at GABA/glycinergic synapses is crucial for the refinement of an inhibitory map.
Volume: 13
Issue: 2
Pages: 232-8
Publication
First Author: Żak M
Year: 2012
Journal: Cell Physiol Biochem
Title: Ergic2, a brain specific interacting partner of Otoferlin.
Volume: 29
Issue: 5-6
Pages: 941-8
Publication
First Author: Johnson SL
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity.
Volume: 110
Issue: 21
Pages: 8720-5
Publication  
First Author: Karagulyan N
Year: 2023
Journal: Front Mol Neurosci
Title: Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses.
Volume: 16
Pages: 1248941
Protein
Organism: Mus musculus/domesticus
Length: 1977  
Fragment?: false
Publication  
First Author: Eitelmann S
Year: 2020
Journal: Int J Mol Sci
Title: Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness.
Volume: 21
Issue: 19
Publication
First Author: Heidrych P
Year: 2009
Journal: Hum Mol Genet
Title: Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell.
Volume: 18
Issue: 15
Pages: 2779-90
Publication
First Author: Vincent PF
Year: 2017
Journal: J Neurosci
Title: Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells.
Volume: 37
Issue: 11
Pages: 2960-2975
Publication    
First Author: Vincent PF
Year: 2015
Journal: Elife
Title: A synaptic F-actin network controls otoferlin-dependent exocytosis in auditory inner hair cells.
Volume: 4
Publication
First Author: Neef J
Year: 2014
Journal: J Neurosci
Title: Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.
Volume: 34
Issue: 3
Pages: 705-16
Publication
First Author: Vogl C
Year: 2016
Journal: EMBO J
Title: Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.
Volume: 35
Issue: 23
Pages: 2536-2552
Publication
First Author: Johnson CP
Year: 2010
Journal: J Cell Biol
Title: Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
Volume: 191
Issue: 1
Pages: 187-97
Publication
First Author: Roux I
Year: 2006
Journal: Cell
Title: Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.
Volume: 127
Issue: 2
Pages: 277-89
Publication
First Author: Beurg M
Year: 2010
Journal: J Neurosci
Title: Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells.
Volume: 30
Issue: 40
Pages: 13281-90
Publication
First Author: Duncker SV
Year: 2013
Journal: J Neurosci
Title: Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells.
Volume: 33
Issue: 22
Pages: 9508-19
Publication
First Author: Kazmierczak M
Year: 2017
Journal: J Neurosci
Title: Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.
Volume: 37
Issue: 13
Pages: 3447-3464
Publication
First Author: Stone JS
Year: 2018
Journal: J Assoc Res Otolaryngol
Title: Characterization of Adult Vestibular Organs in 11 CreER Mouse Lines.
Volume: 19
Issue: 4
Pages: 381-399
Publication
First Author: Wilson L
Year: 2005
Journal: Genome Res
Title: Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations.
Volume: 15
Issue: 8
Pages: 1095-105
Publication  
First Author: Ching YH
Year: 2010
Journal: BMC Genet
Title: High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.
Volume: 11
Pages: 106
Publication
First Author: Vogl C
Year: 2015
Journal: J Cell Sci
Title: Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.
Volume: 128
Issue: 4
Pages: 638-44
Publication
First Author: Schwander M
Year: 2007
Journal: J Neurosci
Title: A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.
Volume: 27
Issue: 9
Pages: 2163-75
Publication
First Author: Mendus D
Year: 2014
Journal: Eur J Neurosci
Title: Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.
Volume: 39
Issue: 8
Pages: 1256-67
Publication
First Author: Ding SL
Year: 2020
Journal: Cell Rep
Title: Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis.
Volume: 31
Issue: 7
Pages: 107648
Publication  
First Author: Wolter S
Year: 2018
Journal: Front Neural Circuits
Title: GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.
Volume: 12
Pages: 65
Publication      
First Author: NIH Neuroscience Blueprint Cre Driver Network
Year: 2009
Journal: MGI Direct Data Submission
Title: Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network
Publication      
First Author: Allen Institute for Brain Science
Year: 2009
Journal: MGI Direct Data Submission
Title: Cre transgenes and knockin alleles created at the Allen Insitute for Brain Science (AIBS)