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Search results 1 to 100 out of 216 for Zap70

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Category: Publication
Type Details Score
Publication
First Author: Lo WL
Year: 2018
Journal: Nat Immunol
Title: Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
Volume: 19
Issue: 7
Pages: 733-741
Publication
First Author: Fallah-Arani F
Year: 2008
Journal: Eur J Immunol
Title: Redundant role for Zap70 in B cell development and activation.
Volume: 38
Issue: 6
Pages: 1721-33
Publication
First Author: Cauwe B
Year: 2014
Journal: Immunology
Title: A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling.
Volume: 141
Issue: 3
Pages: 377-87
Publication  
First Author: Xie J
Year: 2019
Journal: Sci Signal
Title: Phosphotyrosine-dependent interaction between the kinases PKCθ and Zap70 promotes proximal TCR signaling.
Volume: 12
Issue: 577
Publication
First Author: Hsu LY
Year: 2017
Journal: J Exp Med
Title: Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness.
Volume: 214
Issue: 3
Pages: 833-849
Publication  
First Author: Jenkins MR
Year: 2014
Journal: Elife
Title: Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL.
Volume: 3
Pages: e01310
Publication
First Author: Katz ZB
Year: 2017
Journal: Nat Immunol
Title: A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli.
Volume: 18
Issue: 1
Pages: 86-95
Publication
First Author: Borroto A
Year: 2013
Journal: J Immunol
Title: Nck recruitment to the TCR required for ZAP70 activation during thymic development.
Volume: 190
Issue: 3
Pages: 1103-12
Publication
First Author: Yang M
Year: 2015
Journal: Nat Immunol
Title: K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.
Volume: 16
Issue: 12
Pages: 1253-62
Publication
First Author: Gu Y
Year: 2006
Journal: Nat Immunol
Title: RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development.
Volume: 7
Issue: 11
Pages: 1182-90
Publication
First Author: Au-Yeung BB
Year: 2014
Journal: Nat Immunol
Title: Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development.
Volume: 15
Issue: 7
Pages: 687-94
Publication
First Author: Hu H
Year: 2016
Journal: J Exp Med
Title: Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination.
Volume: 213
Issue: 3
Pages: 399-414
Publication
First Author: Thumkeo D
Year: 2020
Journal: Sci Adv
Title: mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.
Volume: 6
Issue: 1
Pages: eaay2432
Publication
First Author: Yokosuka T
Year: 2005
Journal: Nat Immunol
Title: Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.
Volume: 6
Issue: 12
Pages: 1253-62
Publication
First Author: Saini M
Year: 2010
Journal: Sci Signal
Title: Regulation of Zap70 expression during thymocyte development enables temporal separation of CD4 and CD8 repertoire selection at different signaling thresholds.
Volume: 3
Issue: 114
Pages: ra23
Publication
First Author: Au-Yeung BB
Year: 2010
Journal: Nat Immunol
Title: A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity.
Volume: 11
Issue: 12
Pages: 1085-92
Publication
First Author: Cha Y
Year: 2010
Journal: FEBS Lett
Title: SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells.
Volume: 584
Issue: 19
Pages: 4241-6
Publication
First Author: Matsuo T
Year: 2019
Journal: J Immunol
Title: Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation.
Volume: 202
Issue: 11
Pages: 3161-3172
Publication      
First Author: Beutler B
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/01/07
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for want_to.
Publication
First Author: Gong Q
Year: 2001
Journal: J Exp Med
Title: Requirement for tyrosine residues 315 and 319 within zeta chain-associated protein 70 for T cell development.
Volume: 194
Issue: 4
Pages: 507-18
Publication
First Author: Sakaguchi N
Year: 2003
Journal: Nature
Title: Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice.
Volume: 426
Issue: 6965
Pages: 454-60
Publication
First Author: Siggs OM
Year: 2014
Journal: Immunology
Title: A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction.
Volume: 141
Issue: 4
Pages: 587-95
Publication
First Author: Au-Yeung BB
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: A sharp T-cell antigen receptor signaling threshold for T-cell proliferation.
Volume: 111
Issue: 35
Pages: E3679-88
Publication
First Author: Jakob T
Year: 2008
Journal: J Allergy Clin Immunol
Title: Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis.
Volume: 121
Issue: 1
Pages: 179-184.e7
Publication
First Author: Lysechko TL
Year: 2005
Journal: J Immunol
Title: Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.
Volume: 174
Issue: 12
Pages: 7807-14
Publication
First Author: Chandok MR
Year: 2007
Journal: J Immunol
Title: A biochemical signature for rapid recall of memory CD4 T cells.
Volume: 179
Issue: 6
Pages: 3689-98
Publication
First Author: Guerard S
Year: 2016
Journal: Am J Pathol
Title: Reactive Oxygen Species Regulate Innate But Not Adaptive Inflammation in ZAP70-Mutated SKG Arthritic Mice.
Volume: 186
Issue: 9
Pages: 2353-63
Publication
First Author: Peterson LK
Year: 2011
Journal: J Immunol
Title: SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice.
Volume: 186
Issue: 4
Pages: 2273-81
Publication
First Author: Côme C
Year: 2016
Journal: PLoS One
Title: CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection.
Volume: 11
Issue: 4
Pages: e0152996
Publication  
First Author: Nguyen TTT
Year: 2021
Journal: J Exp Med
Title: Cbl-b deficiency prevents functional but not phenotypic T cell anergy.
Volume: 218
Issue: 7
Publication
First Author: Zhao M
Year: 2018
Journal: Nat Commun
Title: Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.
Volume: 9
Issue: 1
Pages: 2627
Publication
First Author: Siggs OM
Year: 2007
Journal: Immunity
Title: Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions.
Volume: 27
Issue: 6
Pages: 912-26
Publication
First Author: Hsu LY
Year: 2009
Journal: J Exp Med
Title: A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity.
Volume: 206
Issue: 11
Pages: 2527-41
Publication
First Author: Salvador JM
Year: 2005
Journal: Nat Immunol
Title: Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases.
Volume: 6
Issue: 4
Pages: 390-5
Publication
First Author: Chiang YJ
Year: 2015
Journal: Int Immunol
Title: Regulation of T cell development by c-Cbl: essential role of Lck.
Volume: 27
Issue: 5
Pages: 245-51
Publication
First Author: Roncagalli R
Year: 2014
Journal: Nat Immunol
Title: Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
Volume: 15
Issue: 4
Pages: 384-392
Publication
First Author: Salvador JM
Year: 2005
Journal: Nat Immunol
Title: The autoimmune suppressor Gadd45alpha inhibits the T cell alternative p38 activation pathway.
Volume: 6
Issue: 4
Pages: 396-402
Publication  
First Author: Jun JE
Year: 2019
Journal: Sci Signal
Title: Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation.
Volume: 12
Issue: 591
Publication
First Author: White AJ
Year: 2010
Journal: J Immunol
Title: Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.
Volume: 185
Issue: 8
Pages: 4769-76
Publication
First Author: Round JL
Year: 2005
Journal: J Exp Med
Title: Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells.
Volume: 201
Issue: 3
Pages: 419-30
Publication
First Author: Chiang YJ
Year: 2013
Journal: PLoS One
Title: CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.
Volume: 8
Issue: 4
Pages: e61761
Publication
First Author: Kuroyama H
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Identification of a novel isoform of ZAP-70, truncated ZAP kinase.
Volume: 315
Issue: 4
Pages: 935-41
Publication
First Author: Tanaka S
Year: 2010
Journal: J Immunol
Title: Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function.
Volume: 185
Issue: 4
Pages: 2295-305
Publication
First Author: Ashouri JF
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
Volume: 116
Issue: 37
Pages: 18517-18527
Publication
First Author: Wencker M
Year: 2014
Journal: Nat Immunol
Title: Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness.
Volume: 15
Issue: 1
Pages: 80-7
Publication
First Author: Wakasa-Morimoto C
Year: 2008
Journal: Int Immunol
Title: Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis.
Volume: 20
Issue: 10
Pages: 1331-42
Publication    
First Author: Beutler B
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission
Volume: v
Publication      
First Author: Choi JH
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for wanna2
Publication      
First Author: Wang K-W
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for waterfowl
Publication
First Author: Endo Y
Year: 2005
Journal: Exp Dermatol
Title: Zeta-chain-associated protein-70 molecule is essential for the proliferation and the final maturation of dendritic epidermal T cells.
Volume: 14
Issue: 3
Pages: 188-93
Publication
First Author: Liu X
Year: 2004
Journal: Nat Immunol
Title: Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo.
Volume: 5
Issue: 3
Pages: 280-8
Publication
First Author: Ashe JM
Year: 1999
Journal: J Exp Med
Title: ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
Volume: 189
Issue: 7
Pages: 1163-8
Publication
First Author: Tone S
Year: 2000
Journal: Immunol Lett
Title: Induction of NK1.1(+) alpha beta TCR(+) T cells by bypassing TCR signals in ZAP-70 deficient mice.
Volume: 73
Issue: 1
Pages: 65-9
Publication
First Author: Iwabuchi K
Year: 2001
Journal: Blood
Title: Defective development of NK1.1+ T-cell antigen receptor alphabeta+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+ CD3- NK-like cells in the thymus.
Volume: 97
Issue: 6
Pages: 1765-75
Publication
First Author: de Barros SC
Year: 2013
Journal: Blood
Title: Intrathymic progenitor cell transplantation across histocompatibility barriers results in the persistence of early thymic progenitors and T-cell differentiation.
Volume: 121
Issue: 11
Pages: 2144-53
Publication
First Author: Kadlecek TA
Year: 1998
Journal: J Immunol
Title: Differential requirements for ZAP-70 in TCR signaling and T cell development.
Volume: 161
Issue: 9
Pages: 4688-94
Publication  
First Author: Kugyelka R
Year: 2019
Journal: Cells
Title: ZAP-70 Regulates Autoimmune Arthritis via Alterations in T Cell Activation and Apoptosis.
Volume: 8
Issue: 5
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for wanna4
Publication      
First Author: Zeng M
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for mesa_verde
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for wanna3
Publication
First Author: Saito T
Year: 1997
Journal: Mamm Genome
Title: Localization of Zap70, the gene for a T cell-specific protein tyrosine kinase, to mouse and rat chromosomes by fluorescence in situ hybridization and molecular genetic linkage analyses.
Volume: 8
Issue: 1
Pages: 45-6
Publication
First Author: Davanture S
Year: 2005
Journal: J Immunol
Title: Selective defect in antigen-induced TCR internalization at the immune synapse of CD8 T cells bearing the ZAP-70(Y292F) mutation.
Volume: 175
Issue: 5
Pages: 3140-9
Publication
First Author: Sinclair C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system.
Volume: 110
Issue: 31
Pages: E2905-14
Publication
First Author: Thaker YR
Year: 2019
Journal: Nat Commun
Title: GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity.
Volume: 10
Issue: 1
Pages: 4804
Publication
First Author: Ishijima SA
Year: 1995
Journal: Cell Immunol
Title: Expression of ZAP-70 gene in the developing thymus and various nonlymphoid tissues of embryonic and adult mice.
Volume: 165
Issue: 2
Pages: 278-83
Publication
First Author: Sosinowski T
Year: 2001
Journal: Immunity
Title: The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection.
Volume: 15
Issue: 3
Pages: 457-66
Publication
First Author: Palacios EH
Year: 2007
Journal: J Exp Med
Title: Distinct roles for Syk and ZAP-70 during early thymocyte development.
Volume: 204
Issue: 7
Pages: 1703-15
Publication
First Author: Posevitz V
Year: 2008
Journal: J Immunol
Title: Regulation of T cell homeostasis by the transmembrane adaptor protein SIT.
Volume: 180
Issue: 3
Pages: 1634-42
Publication
First Author: Napier RJ
Year: 2018
Journal: J Immunol
Title: Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis.
Volume: 201
Issue: 7
Pages: 1889-1898
Publication
First Author: Sood S
Year: 2016
Journal: J Immunol
Title: Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.
Volume: 197
Issue: 2
Pages: 429-40
Publication
First Author: Regan-Komito D
Year: 2020
Journal: Nat Commun
Title: GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis.
Volume: 11
Issue: 1
Pages: 155
Publication
First Author: Nakamura A
Year: 2021
Journal: Sci Transl Med
Title: Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease.
Volume: 13
Issue: 616
Pages: eabg1210
Publication
First Author: Rothe K
Year: 2017
Journal: Eur J Immunol
Title: Autoimmune arthritis induces paired immunoglobulin-like receptor B expression on CD4+ T cells from SKG mice.
Volume: 47
Issue: 9
Pages: 1457-1467
Publication
First Author: Wu DJ
Year: 2014
Journal: PLoS One
Title: Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.
Volume: 9
Issue: 2
Pages: e86677
Publication
First Author: Magnan A
Year: 2001
Journal: J Exp Med
Title: T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.
Volume: 194
Issue: 4
Pages: 491-505
Publication
First Author: Sun G
Year: 2005
Journal: Nat Immunol
Title: The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection.
Volume: 6
Issue: 4
Pages: 373-81
Publication
First Author: Cheng AM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling.
Volume: 94
Issue: 18
Pages: 9797-801
Publication
First Author: Yu Q
Year: 2004
Journal: J Exp Med
Title: IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.
Volume: 200
Issue: 6
Pages: 797-803
Publication
First Author: Colucci F
Year: 2002
Journal: Nat Immunol
Title: Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases.
Volume: 3
Issue: 3
Pages: 288-94
Publication
First Author: Myers MD
Year: 2005
Journal: J Cell Biol
Title: Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation.
Volume: 170
Issue: 2
Pages: 285-94
Publication
First Author: Angibaud J
Year: 2011
Journal: J Neurochem
Title: The immune molecule CD3zeta and its downstream effectors ZAP-70/Syk mediate ephrin signaling in neurons to regulate early neuritogenesis.
Volume: 119
Issue: 4
Pages: 708-22
Publication
First Author: Turner M
Year: 2000
Journal: Immunol Today
Title: Tyrosine kinase SYK: essential functions for immunoreceptor signalling.
Volume: 21
Issue: 3
Pages: 148-54
Publication
First Author: Ulivieri C
Year: 2000
Journal: Mol Immunol
Title: Restoration of thymic development in an Lck(-/-) thymoma overexpressing ZAP-70.
Volume: 37
Issue: 1-2
Pages: 85-90
Publication
First Author: Ku G
Year: 1994
Journal: Immunogenetics
Title: Chromosomal location of the Syk and ZAP-70 tyrosine kinase genes in mice and humans.
Volume: 40
Issue: 4
Pages: 300-2
Publication
First Author: Garcia GG
Year: 1998
Journal: Cell Immunol
Title: Increased Zap-70 association with CD3zeta in CD4 T cells from old mice.
Volume: 190
Issue: 2
Pages: 91-100
Publication
First Author: Zhong L
Year: 2004
Journal: J Immunol
Title: Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways.
Volume: 172
Issue: 3
Pages: 1472-82
Publication
First Author: Arnold CN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Volume: 109
Issue: 31
Pages: 12286-93
Publication
First Author: Ohtsuka M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.
Volume: 101
Issue: 21
Pages: 8126-31
Publication
First Author: Pandey A
Year: 2002
Journal: J Biol Chem
Title: A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling.
Volume: 277
Issue: 21
Pages: 19131-8
Publication
First Author: Lee WH
Year: 2003
Journal: Eur J Immunol
Title: Development of T cells expressing an altered TCR complex.
Volume: 33
Issue: 10
Pages: 2696-705
Publication
First Author: Walter JE
Year: 2010
Journal: J Exp Med
Title: Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.
Volume: 207
Issue: 7
Pages: 1541-54
Publication
First Author: Duarte J
Year: 2010
Journal: PLoS One
Title: Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice.
Volume: 5
Issue: 5
Pages: e10558
Publication
First Author: Wildt KF
Year: 2007
Journal: J Immunol
Title: The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer.
Volume: 179
Issue: 7
Pages: 4405-14
Publication
First Author: Gong Q
Year: 1997
Journal: Immunity
Title: Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase.
Volume: 7
Issue: 3
Pages: 369-77
Publication
First Author: Mingueneau M
Year: 2008
Journal: Nat Immunol
Title: The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.
Volume: 9
Issue: 5
Pages: 522-32
Publication
First Author: Myers MD
Year: 2006
Journal: Nat Immunol
Title: Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.
Volume: 7
Issue: 1
Pages: 57-66
Publication
First Author: Park J
Year: 2022
Journal: Cancer Immunol Res
Title: The Pellino1-PKCθ Signaling Axis Is an Essential Target for Improving Antitumor CD8+ T-lymphocyte Function.
Volume: 10
Issue: 3
Pages: 327-342
Publication
First Author: Alampour-Rajabi S
Year: 2015
Journal: FASEB J
Title: MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis.
Volume: 29
Issue: 11
Pages: 4497-511
Publication
First Author: Latour S
Year: 1996
Journal: J Biol Chem
Title: Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases.
Volume: 271
Issue: 37
Pages: 22782-90