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Search results 101 to 195 out of 195 for Stk39

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Categories

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 2B top, merge
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5471815
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472010
Age: postnatal
Specimen Label: 2B bottom, merge
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3551228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 2A top, merge
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3551228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 2A bottom, merge
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3551228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 2B top, merge
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5471815
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3551228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5472010
Age: postnatal
Specimen Label: 2B bottom, merge
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1795228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 3B Wild Type
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1795228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 3B HET
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
     
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1795228
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 3B Knockout
Detected: false
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1927928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 3B Wild Type
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1927928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 3B HET
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
     
Probe: MGI:5471829
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1927928
Stage: TS28
Assay Id: MGI:5471843
Age: postnatal
Specimen Label: 3B Knockout
Detected: false
Specimen Num: 6
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Publication
20091762 | J:191566
First Author: Rafiqi FH
Year: 2010
Journal: EMBO Mol Med
Title: Role of the WNK-activated SPAK kinase in regulating blood pressure.
Volume: 2
Issue: 2
Pages: 63-75
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Publication
24173353 | J:205045
First Author: Gamba G
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Regulation of NKCC2 activity by SPAK truncated isoforms.
Volume: 306
Issue: 1
Pages: F49-50
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Publication
25651563 | J:280166
First Author: Wade JB
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: SPAK-mediated NCC regulation in response to low-K+ diet.
Volume: 308
Issue: 8
Pages: F923-31
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Publication
25893600 | J:222702
First Author: Grimm PR
Year: 2015
Journal: J Clin Invest
Title: Integrated compensatory network is activated in the absence of NCC phosphorylation.
Volume: 125
Issue: 5
Pages: 2136-50
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Publication
29122955 | J:256298
 
First Author: Koumangoye R
Year: 2017
Journal: Physiol Rep
Title: DNPEP is not the only peptidase that produces SPAK fragments in kidney.
Volume: 5
Issue: 21
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Publication
24393035 | J:211319
First Author: de Los Heros P
Year: 2014
Journal: Biochem J
Title: The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.
Volume: 458
Issue: 3
Pages: 559-73
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Publication
24133122 | J:204689
First Author: Park HJ
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2.
Volume: 305
Issue: 12
Pages: F1687-96
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Publication
21705622 | J:179189
First Author: Yan Y
Year: 2011
Journal: J Immunol
Title: Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice.
Volume: 187
Issue: 3
Pages: 1496-505
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Publication
24761002 | J:211079
First Author: Castañeda-Bueno M
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Modulation of NCC activity by low and high K(+) intake: insights into the signaling pathways involved.
Volume: 306
Issue: 12
Pages: F1507-19
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Publication
26861815 | J:264975
First Author: Zhao H
Year: 2017
Journal: J Cereb Blood Flow Metab
Title: Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke.
Volume: 37
Issue: 2
Pages: 550-563
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Publication
22977235 | J:192476
First Author: Grimm PR
Year: 2012
Journal: J Biol Chem
Title: SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner.
Volume: 287
Issue: 45
Pages: 37673-90
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Publication
33719576 | J:307444
First Author: Mukherjee A
Year: 2021
Journal: Am J Physiol Renal Physiol
Title: Roles of WNK4 and SPAK in K+-mediated dephosphorylation of the NaCl cotransporter.
Volume: 320
Issue: 5
Pages: F719-F733
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Publication
20385770 | J:162573
First Author: Reiche J
Year: 2010
Journal: Mol Cell Biol
Title: SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.
Volume: 30
Issue: 12
Pages: 3027-37
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Publication
27068441 | J:286060
First Author: Ferdaus MZ
Year: 2016
Journal: J Physiol
Title: SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.
Volume: 594
Issue: 17
Pages: 4945-66
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Publication
29459793 | J:263369
First Author: Rafael C
Year: 2018
Journal: Sci Rep
Title: Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.
Volume: 8
Issue: 1
Pages: 3249
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Publication
24039833 | J:207559
First Author: Chu PY
Year: 2013
Journal: PLoS One
Title: SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.
Volume: 8
Issue: 9
Pages: e72969
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Publication
27853306 | J:250169
 
First Author: Liu YL
Year: 2016
Journal: Sci Rep
Title: OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis.
Volume: 6
Pages: 37205
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Publication
19307180 | J:150513
First Author: Geng Y
Year: 2009
Journal: J Biol Chem
Title: The Ste20 kinases Ste20-related proline-alanine-rich kinase and oxidative-stress response 1 regulate NKCC1 function in sensory neurons.
Volume: 284
Issue: 21
Pages: 14020-8
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Publication
25515571 | J:230986
First Author: Vorontsova I
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses.
Volume: 56
Issue: 1
Pages: 310-21
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Publication
14563843 | J:139340
First Author: Piechotta K
Year: 2003
Journal: J Biol Chem
Title: Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase.
Volume: 278
Issue: 52
Pages: 52848-56
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Publication
20231443 | J:158651
First Author: Hengl T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Molecular components of signal amplification in olfactory sensory cilia.
Volume: 107
Issue: 13
Pages: 6052-7
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Publication
25362046 | J:216760
First Author: Dbouk HA
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.
Volume: 111
Issue: 45
Pages: 15999-6004
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Publication
21907141 | J:176654
First Author: McCormick JA
Year: 2011
Journal: Cell Metab
Title: A SPAK isoform switch modulates renal salt transport and blood pressure.
Volume: 14
Issue: 3
Pages: 352-64
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Publication
31615901 | J:283808
 
First Author: Watanabe M
Year: 2019
Journal: Sci Signal
Title: Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
Volume: 12
Issue: 603
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Publication
31736353 | J:294764
First Author: Thomson MN
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.
Volume: 318
Issue: 1
Pages: F216-F228
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Publication
29412702 | J:280485
First Author: Lazo-Fernandez Y
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: α-Ketoglutarate stimulates pendrin-dependent Cl- absorption in the mouse CCD through protein kinase C.
Volume: 315
Issue: 1
Pages: F7-F15
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Publication
21486947 | J:182953
First Author: Chiga M
Year: 2011
Journal: J Cell Sci
Title: Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.
Volume: 124
Issue: Pt 9
Pages: 1391-5
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Publication
31786261 | J:293611
 
First Author: Hung CM
Year: 2020
Journal: Biochem Pharmacol
Title: WNK4-SPAK modulates lipopolysaccharide-induced macrophage activation.
Volume: 171
Pages: 113738
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Publication
18800028 | J:162717
First Author: Chiga M
Year: 2008
Journal: Kidney Int
Title: Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.
Volume: 74
Issue: 11
Pages: 1403-9
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Publication
25565204 | J:219977
First Author: Terker AS
Year: 2015
Journal: Cell Metab
Title: Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride.
Volume: 21
Issue: 1
Pages: 39-50
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Publication
21768522 | J:281507
First Author: Bergaya S
Year: 2011
Journal: Hypertension
Title: WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.
Volume: 58
Issue: 3
Pages: 439-45
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Publication
27519267 | J:347025
 
First Author: Lin TJ
Year: 2016
Journal: Free Radic Biol Med
Title: SPAK plays a pathogenic role in IgA nephropathy through the activation of NF-κB/MAPKs signaling pathway.
Volume: 99
Pages: 214-224
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Publication
21321328 | J:182998
First Author: Richardson C
Year: 2011
Journal: J Cell Sci
Title: Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.
Volume: 124
Issue: Pt 5
Pages: 789-800
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Publication
24808538 | J:211041
First Author: Davies M
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.
Volume: 307
Issue: 1
Pages: F96-F106
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Publication
12386165 | J:80982
First Author: Piechotta K
Year: 2002
Journal: J Biol Chem
Title: Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).
Volume: 277
Issue: 52
Pages: 50812-9
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Publication
21317537 | J:172037
First Author: Yang D
Year: 2011
Journal: J Clin Invest
Title: IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.
Volume: 121
Issue: 3
Pages: 956-65
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Publication
27782176 | J:278187
 
First Author: Zhang J
Year: 2016
Journal: Sci Rep
Title: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Volume: 6
Pages: 35986
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Publication
- | J:82961
     
First Author: JAX National Heart, Lung and Blood Program for Genomic Applications (PGA)
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program
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Publication
35379995 | J:335575
First Author: Duy PQ
Year: 2022
Journal: Nat Neurosci
Title: Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus.
Volume: 25
Issue: 4
Pages: 458-473
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Publication
- | J:169366
     
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
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Publication
16284245 | J:103829
First Author: Chen B
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
Volume: 102
Issue: 47
Pages: 17184-9
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 355
Description: RFRV motif; mediates interaction with STK39
Type: short sequence motif
End: 358
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Allele
Stk39<tm1Pawe> | MGI:6423627
Name: serine/threonine kinase 39; targeted mutation 1, Paul A Welling
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout
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Allele
Stk39<tm1.1Pawe> | MGI:6423628
Name: serine/threonine kinase 39; targeted mutation 1.1, Paul A Wellling
Allele Type: Targeted
Attribute String: Constitutively active, Epitope tag
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Strain
MGI:6423630 | B6.129-Stk39<tm1Pawe> Pvalb<tm1(cre)Arbr>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Stk39/Stk39
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk39/Stk39 Pvalb/Pvalb<+>
Background: B6.129-Stk39 Pvalb
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk39/Stk39
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
27400149 | J:259583
First Author: Köchl R
Year: 2016
Journal: Nat Immunol
Title: WNK1 kinase balances T cell adhesion versus migration in vivo.
Volume: 17
Issue: 9
Pages: 1075-83
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Publication
29526533 | J:261116
 
First Author: Ten Klooster JP
Year: 2018
Journal: Arch Biochem Biophys
Title: Type 2 diabetes-related proteins derived from an in vitro model of inflamed fat tissue.
Volume: 644
Pages: 81-92
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