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Search results 101 to 135 out of 135 for Sik3

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0.022s
Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase SIK3
Type: chain
End: 1369
Protein
Organism: Mus musculus/domesticus
Length: 1369  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1214  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
Publication  
First Author: Csukasi F
Year: 2018
Journal: Sci Transl Med
Title: The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling.
Volume: 10
Issue: 459
Publication
First Author: Jaitovich A
Year: 2010
Journal: Biochim Biophys Acta
Title: Intracellular sodium sensing: SIK1 network, hormone action and high blood pressure.
Volume: 1802
Issue: 12
Pages: 1140-9
Publication
First Author: Takemori H
Year: 2003
Journal: J Steroid Biochem Mol Biol
Title: Salt-inducible kinase-mediated regulation of steroidogenesis at the early stage of ACTH-stimulation.
Volume: 85
Issue: 2-5
Pages: 397-400
Publication
First Author: Ahmed AA
Year: 2010
Journal: Cancer Cell
Title: SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.
Volume: 18
Issue: 2
Pages: 109-21
Publication
First Author: Katoh Y
Year: 2004
Journal: Mol Cell Endocrinol
Title: Salt-inducible kinase (SIK) isoforms: their involvement in steroidogenesis and adipogenesis.
Volume: 217
Issue: 1-2
Pages: 109-12
Publication
First Author: Hietakangas V
Year: 2008
Journal: Cell Metab
Title: TORCing up metabolic control in the brain.
Volume: 7
Issue: 5
Pages: 357-8
Protein Domain
Type: Domain
Description: SIKs are serine/threonine kinasse that are part of a complex network that regulates Na,K-ATPase to maintain sodium homeostasis and blood pressure []. Vertebrates contain three forms of SIKs (SIK1-3) from three distinct genes, which display tissue-specific effects. SIK1, also called SNF1LK, controls steroidogenic enzyme production in adrenocortical cells []. In the brain, both SIK1 and SIK2 regulate energy metabolism []. SIK2, also called QIK or SNF1LK2, is involved in the regulation of gluconeogenesis in the liver and lipogenesis in adipose tissues, where it phosphorylates the insulin receptor substrate-1 []. In the liver, SIK3 (also called QSK) regulates cholesterol and bile acid metabolism []. In addition, SIK2 plays an important role in the initiation of mitosis and regulates the localization of C-Nap1, a centrosome linker protein [].
Publication
First Author: Jeppesen J
Year: 2013
Journal: Diabetes
Title: LKB1 regulates lipid oxidation during exercise independently of AMPK.
Volume: 62
Issue: 5
Pages: 1490-9
Publication
First Author: Park M
Year: 2020
Journal: Sci Rep
Title: Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Volume: 10
Issue: 1
Pages: 8676
Publication
First Author: Kim MK
Year: 2019
Journal: Cell Death Dis
Title: Salt-inducible kinase 1 regulates bone anabolism via the CRTC1-CREB-Id1 axis.
Volume: 10
Issue: 11
Pages: 826
Publication  
First Author: Nishimori S
Year: 2021
Journal: Bone
Title: PTHrP targets salt-inducible kinases, HDAC4 and HDAC5, to repress chondrocyte hypertrophy in the growth plate.
Volume: 142
Pages: 115709
Publication
First Author: van Gijsel-Bonnello M
Year: 2022
Journal: J Biol Chem
Title: Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury.
Volume: 298
Issue: 12
Pages: 102644
Publication
First Author: Houde VP
Year: 2014
Journal: Biochem J
Title: Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity.
Volume: 458
Issue: 1
Pages: 41-56
Publication
First Author: Lombardi MS
Year: 2017
Journal: PLoS One
Title: Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis.
Volume: 12
Issue: 10
Pages: e0185426
Publication      
First Author: Wang G
Year: 2022
Journal: J Neurosci
Title: Somatic genetics analysis of sleep in adult mice.
Protein
Organism: Mus musculus/domesticus
Length: 1319  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 779  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 929  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
Publication
First Author: Guo A
Year: 2014
Journal: Mol Cell Proteomics
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume: 13
Issue: 1
Pages: 372-87
Publication
First Author: Villén J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Large-scale phosphorylation analysis of mouse liver.
Volume: 104
Issue: 5
Pages: 1488-93
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112