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Search results 301 to 342 out of 342 for Plk4

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Type Details Score
Publication
21245385 | J:170612
First Author: de Cárcer G
Year: 2011
Journal: Mol Cell Biol
Title: Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression.
Volume: 31
Issue: 6
Pages: 1225-39
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Publication
24071582 | J:211415
First Author: Fischer M
Year: 2014
Journal: Nucleic Acids Res
Title: Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.
Volume: 42
Issue: 1
Pages: 163-80
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Publication
32931487 | J:296384
First Author: Ching K
Year: 2020
Journal: PLoS Biol
Title: Centrioles are amplified in cycling progenitors of olfactory sensory neurons.
Volume: 18
Issue: 9
Pages: e3000852
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Publication
34266887 | J:321474
First Author: Shoshani O
Year: 2021
Journal: Genes Dev
Title: Transient genomic instability drives tumorigenesis through accelerated clonal evolution.
Volume: 35
Issue: 15-16
Pages: 1093-1108
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Publication
14592974 | -
First Author: Cheng KY
Year: 2003
Journal: EMBO J
Title: The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Volume: 22
Issue: 21
Pages: 5757-68
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Publication
20148280 | -
First Author: Park JE
Year: 2010
Journal: Cell Mol Life Sci
Title: Polo-box domain: a versatile mediator of polo-like kinase function.
Volume: 67
Issue: 12
Pages: 1957-70
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Publication
19305416 | -
First Author: Archambault V
Year: 2009
Journal: Nat Rev Mol Cell Biol
Title: Polo-like kinases: conservation and divergence in their functions and regulation.
Volume: 10
Issue: 4
Pages: 265-75
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Publication
17188028 | -
First Author: Dai W
Year: 2006
Journal: Mol Cell
Title: Grabbing Plk1 by the PBD.
Volume: 24
Issue: 4
Pages: 489-90
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Publication
21399614 | -
First Author: Jakobsen L
Year: 2011
Journal: EMBO J
Title: Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Volume: 30
Issue: 8
Pages: 1520-35
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Publication
24075808 | J:203425
First Author: Klos Dehring DA
Year: 2013
Journal: Dev Cell
Title: Deuterosome-mediated centriole biogenesis.
Volume: 27
Issue: 1
Pages: 103-12
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Protein Domain
IPR041470 | GCP_N
Type: Domain
Description: This is the N-terminal domain found in components of the gamma-tubulin complex proteins (GCPs). Proteins containing this domain include spindle pole body (SBP) components such as Spc97 and Spc98 which function as the microtubule-organizing centre in yeast []. Proteins containing this domain also include human GCP4 (Gamma-tubulin complex component 4), which has been structurally elucidated []. Functional studies have shown that the N-terminal domain defines the functional identity of GCPs, suggesting that all GCPs are incorporated into the helix of gamma-tubulin small complexes (gTURCs) via lateral interactions between their N-terminal domains. Thereby, they define the direct neighbours and position the GCPs within the helical wall of gTuRC []. Sequence alignment of human GCPs based on the GCP4 structure helped delineate conserved regions in the N- and C-terminal domains []. In addition to the conserved sequences, the N-terminal domains carry specific insertions of various sizes depending on the GCP, i.e. internal insertions or N-terminal extensions. These insertions may equally contribute to the function of individual GCPs as they have been implied in specific interactions with regulatory or structural proteins. For instance, GCP6 carries a large internal insertion phosphorylated by Plk4 and containing a domain of interaction with keratins, whereas the N-terminal extension of GCP3 interacts with the recruitment protein MOZART1 [].
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Publication
21654194 | -
First Author: de Cárcer G
Year: 2011
Journal: Cell Cycle
Title: From Plk1 to Plk5: functional evolution of polo-like kinases.
Volume: 10
Issue: 14
Pages: 2255-62
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Publication
15838519 | -
First Author: van Vugt MA
Year: 2005
Journal: Oncogene
Title: Getting in and out of mitosis with Polo-like kinase-1.
Volume: 24
Issue: 17
Pages: 2844-59
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Publication
27660388 | -
First Author: Farache D
Year: 2016
Journal: J Biol Chem
Title: Functional Analysis of γ-Tubulin Complex Proteins Indicates Specific Lateral Association via Their N-terminal Domains.
Volume: 291
Issue: 44
Pages: 23112-23125
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Protein
Q8BKJ3
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: true
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Protein
Q8BUB7
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
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Protein
E9Q0R3
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
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Publication
21725292 | -
First Author: Guillet V
Year: 2011
Journal: Nat Struct Mol Biol
Title: Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation.
Volume: 18
Issue: 8
Pages: 915-9
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Protein
Q921G8
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
P58854
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
Q9D4F8
Organism: Mus musculus/domesticus
Length: 667  
Fragment?: false
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Protein
Q8BKN5
Organism: Mus musculus/domesticus
Length: 1024  
Fragment?: false
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Protein
G5E8P0
Organism: Mus musculus/domesticus
Length: 1769  
Fragment?: false
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Protein
Q8BWR3
Organism: Mus musculus/domesticus
Length: 666  
Fragment?: false
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Protein
Q543T6
Organism: Mus musculus/domesticus
Length: 667  
Fragment?: false
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Protein
A0A1B0GR08
Organism: Mus musculus/domesticus
Length: 900  
Fragment?: true
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Protein
Q8R2X3
Organism: Mus musculus/domesticus
Length: 690  
Fragment?: false
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Protein
Q8BZZ0
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: false
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Protein
Q3UY55
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: false
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Protein
Q3UIT6
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
E9Q6P4
Organism: Mus musculus/domesticus
Length: 1761  
Fragment?: false
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Protein
Q3TAJ6
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
Q3TIB7
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
Q3TN67
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
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Protein
Q8BYN2
Organism: Mus musculus/domesticus
Length: 666  
Fragment?: false
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Protein
Q8BKL6
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
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Protein
Q3U6E9
Organism: Mus musculus/domesticus
Length: 666  
Fragment?: false
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Publication
11134079 | -
First Author: Gunawardane RN
Year: 2000
Journal: J Cell Biol
Title: Characterization and reconstitution of Drosophila gamma-tubulin ring complex subunits.
Volume: 151
Issue: 7
Pages: 1513-24
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Publication
21938754 | -
First Author: Chmielecki J
Year: 2012
Journal: Genes Chromosomes Cancer
Title: Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.
Volume: 51
Issue: 1
Pages: 54-65
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Protein
Q80U29
Organism: Mus musculus/domesticus
Length: 1471  
Fragment?: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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