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Search results 301 to 400 out of 420 for Txnip

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Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312656
Specimen Label: MRC Harwell_1312656
Detected: true
Specimen Num: 22
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Specimen Label: DC32; Specimen C1379
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Specimen Label: DC32; Specimen C1379
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312661
Specimen Label: MRC Harwell_1312661
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_05
Specimen Label: euxassay_006657_05
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_06
Specimen Label: euxassay_006657_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_07
Specimen Label: euxassay_006657_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_08
Specimen Label: euxassay_006657_08
Detected: true
Specimen Num: 8
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_09
Specimen Label: euxassay_006657_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_10
Specimen Label: euxassay_006657_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_11
Specimen Label: euxassay_006657_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_12
Specimen Label: euxassay_006657_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_13
Specimen Label: euxassay_006657_13
Detected: true
Specimen Num: 13
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_14
Specimen Label: euxassay_006657_14
Detected: true
Specimen Num: 14
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_15
Specimen Label: euxassay_006657_15
Detected: true
Specimen Num: 15
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_16
Specimen Label: euxassay_006657_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_17
Specimen Label: euxassay_006657_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_18
Specimen Label: euxassay_006657_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1556461
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1779123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829033
Age: embryonic day 14.5
Image: euxassay_006657_19
Specimen Label: euxassay_006657_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312641
Specimen Label: MRC Harwell_1312641
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312651
Specimen Label: MRC Harwell_1312651
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312659
Specimen Label: MRC Harwell_1312659
Detected: true
Specimen Num: 25
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312661
Specimen Label: MRC Harwell_1312661
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: DC32; Specimen C1379
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Note: Expression was weak in whisker follicle.
Specimen Label: DC32; Specimen C1379
Detected: true
Specimen Num: 1
•
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Publication
25145386 | J:217834
First Author: Imamura M
Year: 2014
Journal: Biochem J
Title: MondoA deficiency enhances sprint performance in mice.
Volume: 464
Issue: 1
Pages: 35-48
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Publication
29749372 | J:262940
First Author: Muri J
Year: 2018
Journal: Nat Commun
Title: The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation.
Volume: 9
Issue: 1
Pages: 1851
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Publication
21119640 | J:220940
 
First Author: Yoshihara E
Year: 2010
Journal: Nat Commun
Title: Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity.
Volume: 1
Pages: 127
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Publication
18974273 | J:146985
First Author: Oka S
Year: 2009
Journal: Endocrinology
Title: Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function.
Volume: 150
Issue: 3
Pages: 1225-34
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Publication
10843682 | J:62834
First Author: Junn E
Year: 2000
Journal: J Immunol
Title: Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function.
Volume: 164
Issue: 12
Pages: 6287-95
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Publication
33901495 | J:311109
First Author: Lu Y
Year: 2021
Journal: Gastroenterology
Title: MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment.
Volume: 161
Issue: 2
Pages: 575-591.e16
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Publication
18555775 | J:138150
First Author: Ago T
Year: 2008
Journal: Cell
Title: A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy.
Volume: 133
Issue: 6
Pages: 978-93
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Publication
23584856 | J:198465
First Author: Wattanachanya L
Year: 2013
Journal: Endocrinology
Title: Increased bone mass in mice lacking the adipokine apelin.
Volume: 154
Issue: 6
Pages: 2069-80
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Publication
11473059 | J:88209
First Author: Shike T
Year: 2001
Journal: Diabetes
Title: Susceptibility and negative epistatic loci contributing to type 2 diabetes and related phenotypes in a KK/Ta mouse model.
Volume: 50
Issue: 8
Pages: 1943-8
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Publication
20826751 | J:164284
First Author: Kwon HJ
Year: 2010
Journal: J Immunol
Title: Vitamin D3 upregulated protein 1 suppresses TNF-α-induced NF-κB activation in hepatocarcinogenesis.
Volume: 185
Issue: 7
Pages: 3980-9
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Publication
30208322 | J:271254
First Author: Han CY
Year: 2018
Journal: Cell Rep
Title: FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury.
Volume: 24
Issue: 11
Pages: 2985-2999
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Publication
36624847 | J:332404
First Author: Lau KH
Year: 2023
Journal: iScience
Title: PPARγ and C/EBPα response to acute cold stress in brown adipose tissue.
Volume: 26
Issue: 1
Pages: 105848
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Publication
34708032 | J:312383
 
First Author: Nelson MM
Year: 2021
Journal: Front Cell Dev Biol
Title: Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion.
Volume: 9
Pages: 693595
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Publication
9537422 | J:47109
First Author: Castellani LW
Year: 1998
Journal: Nat Genet
Title: Mapping a gene for combined hyperlipidaemia in a mutant mouse strain.
Volume: 18
Issue: 4
Pages: 374-7
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Publication
11252174 | J:68107
First Author: Pajukanta P
Year: 2001
Journal: Mamm Genome
Title: Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL.
Volume: 12
Issue: 3
Pages: 238-45
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Publication
17143286 | J:117491
First Author: Schmahl J
Year: 2007
Journal: Nat Genet
Title: PDGF signaling specificity is mediated through multiple immediate early genes.
Volume: 39
Issue: 1
Pages: 52-60
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Publication
32005751 | J:287361
 
First Author: Pakarinen E
Year: 2020
Journal: eNeuro
Title: MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
Volume: 7
Issue: 1
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Publication
35129674 | J:327300
First Author: Pakarinen E
Year: 2022
Journal: Cell Mol Life Sci
Title: CDNF and MANF regulate ER stress in a tissue-specific manner.
Volume: 79
Issue: 2
Pages: 124
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Publication
37349316 | J:336923
First Author: Jiang X
Year: 2023
Journal: Nat Commun
Title: Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice.
Volume: 14
Issue: 1
Pages: 3729
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Publication
21377456 | J:169829
First Author: Pyrgaki C
Year: 2011
Journal: Dev Biol
Title: Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion.
Volume: 353
Issue: 1
Pages: 38-49
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
19906978 | J:154739
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30197082 | J:268939
First Author: Sullivan WJ
Year: 2018
Journal: Cell
Title: Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization.
Volume: 175
Issue: 1
Pages: 117-132.e21
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Allele
Txnip<em1Smoc> | MGI:7293049
Name: thioredoxin interacting protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
26919541 | -
First Author: Liu S
Year: 2016
Journal: FEBS Lett
Title: Structural basis for a novel interaction between TXNIP and Vav2.
Volume: 590
Issue: 6
Pages: 857-65
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Publication
30980800 | J:277219
First Author: Fertan E
Year: 2019
Journal: Am J Pathol
Title: Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease.
Volume: 189
Issue: 7
Pages: 1435-1450
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Interaction Experiment
Wu N (2013)
Description: AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.
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Publication
23453806 | -
First Author: Wu N
Year: 2013
Journal: Mol Cell
Title: AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.
Volume: 49
Issue: 6
Pages: 1167-75
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Protein Domain
IPR035880 | VAV2_SH2
Type: Domain
Description: This entry represents the SH2 domain of VAV2, which is a member of the VAV family. The SH2 domain of VAV2 has been shown to interact with PPxY motifs of TXNIP (thioredoxin-interacting protein) []. The VAV protein family members are multiple domain proteins, including Vav from flies and VAV1/2/3 from mammals. VAV1 predominates in hematopoietic cells, whereas VAV2 and VAV3 are more broadly expressed. They have a calponin homology (CH) domain, an acidic domain (AC), a Dbl homology (DH) domain, a pleckstrin homology (PH) domain, a cysteine-rich (CR) domain containing a zinc finger, and a complex region with SH2 and SH3 domains. Therefore they may participate in the activity of several pathways [, ]. They are signal transducer proteins that couple tyrosine kinase signals with the activation of the Rho/Rac GTPases, [, , ].
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Publication
32877674 | J:299203
First Author: Muraleedharan R
Year: 2020
Journal: Cell Rep
Title: AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival.
Volume: 32
Issue: 9
Pages: 108092
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Publication
28606928 | J:247199
First Author: Chau GC
Year: 2017
Journal: J Cell Biol
Title: mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress.
Volume: 216
Issue: 7
Pages: 2091-2105
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Publication
29282201 | J:258313
First Author: Richards P
Year: 2018
Journal: Diabetes
Title: MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells.
Volume: 67
Issue: 3
Pages: 461-472
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Publication
25017793 | J:218491
First Author: Gao P
Year: 2014
Journal: Biochim Biophys Acta
Title: Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathy.
Volume: 1843
Issue: 11
Pages: 2448-60
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Publication
29339473 | J:257760
First Author: Nagaraj K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action.
Volume: 115
Issue: 5
Pages: 1045-1050
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Publication
26154105 | J:325925
First Author: Gao K
Year: 2015
Journal: J Cell Mol Med
Title: A novel TXNIP-based mechanism for Cx43-mediated regulation of oxidative drug injury.
Volume: 19
Issue: 10
Pages: 2469-80
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Publication
33600943 | J:337362
 
First Author: Collins JA
Year: 2021
Journal: Free Radic Biol Med
Title: Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes.
Volume: 166
Pages: 90-103
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Publication
21270263 | J:169785
First Author: Koenen TB
Year: 2011
Journal: Diabetes
Title: Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue.
Volume: 60
Issue: 2
Pages: 517-24
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Publication
32723174 | J:296859
First Author: Zhou W
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Glucagon-like peptide-1 receptor mediates the beneficial effect of liraglutide in an acute lung injury mouse model involving the thioredoxin-interacting protein.
Volume: 319
Issue: 3
Pages: E568-E578
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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