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Search results 501 to 582 out of 582 for Mafg

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Type Details Score
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Interaction Experiment
Motohashi H (2006)
Description: MafG sumoylation is required for active transcriptional repression.
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HT Experiment
E-GEOD-65500 | Compound mouse mutants of bZIP transcription factors MafG and MafK reveal a regulatory network of non-crystallin genes linked to cataract
Series Id: GSE65500
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
31398338 | J:279945
First Author: Sanghvi VR
Year: 2019
Journal: Cell
Title: The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.
Volume: 178
Issue: 4
Pages: 807-819.e21
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HT Experiment
GSE207853 | Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Mafg<em1Smoc> | MGI:7290932
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tg(Mafg-Nfe2l1)6Mym | MGI:5804124
Name: transgene insertion 6, Masayuki Yamamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Mafg-Nfe2l1)1Mym | MGI:5804114
Name: transgene insertion 1, Masayuki Yamamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5804126 | B6J.Cg-Tg(Mafg-Nfe2l1)6Mym
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:5804119 | B6J.Cg-Tg(Mafg-Nfe2l1)1Mym
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:6353257 | B6.Cg-Tg(Mafg-Nfe2l1)1Mym/MymRbrc
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(Mafg-Nfe2l1)1Mym/?
Background: involves: C57BL/6J * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Mafg-Nfe2l1)1Mym/?
Background: B6J.Cg-Tg(Mafg-Nfe2l1)1Mym
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Mafg-Nfe2l1)6Mym/?
Background: involves: C57BL/6J * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Mafg-Nfe2l1)6Mym/?
Background: B6J.Cg-Tg(Mafg-Nfe2l1)6Mym
Zygosity: ot
Has Mutant Allele: true
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Publication
9628487 | -
First Author: Rupert PB
Year: 1998
Journal: Nat Struct Biol
Title: A new DNA-binding motif in the Skn-1 binding domain-DNA complex.
Volume: 5
Issue: 6
Pages: 484-91
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Protein Domain
IPR008917 | TF_DNA-bd_sf
Type: Homologous_superfamily
Description: The DNA-binding domain of certain eukaryotic transcription factors displays a distinctive helix-turn-helix (HTH) motif. The MafG basic region-leucine zipper (bZIP) protein and the Caenorhabditis elegans Skn-1 transcription factor share this HTH motif. MafG is a member of the Maf family of proteins, which are a subgroup of bZIP proteins that function as transcriptional regulators of cellular differentiation. Mafs can form either homodimers, or heterodimers with other bZIP proteins through their leucine zipper domains. MafG proteins are small Mafs that lack a putative transactivation domain. The DNA-binding domain of MafG contains the conserved Maf extended homology region (EHR), which is not present in other bZIP proteins. The EHR together with the basic region are responsible for the DNA-binding specificity of Mafs. Skn-1 is a transcription factor that specifies mesodermal development in C. elegans. Skn-1 and MafG share a conserved DNA-binding motif, however Skn-1 lacks the leucine zipper dimerisation domain that is found in all bZIP proteins. Skn-1 acts as a monomer. The DNA-binding domains in MafG []and Skn-1 []share structural similarity, despite a sequence identity of only 25%. The domain fold consists of three (MafG) to four (Skn-1) helices, where the long C-terminal helix protrudes from the domain and binds to DNA. MafG lacks the N-terminal helix of Skn-1. A basic cluster of residues is present on the surface of the domain, which together with the amino acid sequence motif, NXXYAXXCR, forms a DNA-binding surface. MafG and Skn-1 may use a common DNA-binding mode. However, the involvement of helix 2 (H2) in DNA recognition differs between MafG and Skn-1, with two residues at the beginning of H2 in MafG contributing to the unique DNA-binding specificity of Mafs.
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Protein
Q9WTM4
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
Q07279
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Protein
Q61985
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q3U4L3
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q3U5L0
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q3V3M1
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
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Protein
Q6KAM4
Organism: Mus musculus/domesticus
Length: 767  
Fragment?: true
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Protein
D3Z224
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q9CW60
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: true
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Protein
Q3UVS3
Organism: Mus musculus/domesticus
Length: 646  
Fragment?: true
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Protein
A2A6D2
Organism: Mus musculus/domesticus
Length: 742  
Fragment?: false
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Protein
Q3UUW2
Organism: Mus musculus/domesticus
Length: 654  
Fragment?: true
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Protein
Q3UFI8
Organism: Mus musculus/domesticus
Length: 572  
Fragment?: false
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Protein
Q3UZC1
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
Q3U5G2
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: true
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Protein
Q9Z2E8
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: false
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Protein
Q6GTN8
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
A0A0R4J0Y5
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Publication
25041126 | J:230118
First Author: Hirotsu Y
Year: 2014
Journal: Genes Cells
Title: Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice.
Volume: 19
Issue: 8
Pages: 650-65
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Protein Domain
IPR028574 | MafK
Type: Family
Description: Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors. The Maf family is divided into two subclasses, large Mafs and small Mafs (MafF, MafK []and MafG []). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. Small Mafs can act as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can then displace active dimers. Small Mafs lack a transactivator domain, but they can also serve as transcriptional activators by dimerising with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites.The small Mafs (MafF, MafG and MafK) appear to be crucial regulators of mammalian gene expression. Small Mafs are also involved in regulating stress response and detoxification pathways [].
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Protein
Q61827
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
Q3UP84
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
Q3U568
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
P97302
Organism: Mus musculus/domesticus
Length: 739  
Fragment?: false
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Protein
P97303
Organism: Mus musculus/domesticus
Length: 839  
Fragment?: false
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Protein
P54846
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Protein
P54841
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
Q8CF90
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
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Protein
O54791
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
P54843
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein
P05627
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
P15066
Organism: Mus musculus/domesticus
Length: 341  
Fragment?: false
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Protein
P09450
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q60795
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
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Protein
Q569U6
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q543Y0
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Protein
A0A1S6GWH7
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
Q52L49
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
Q3URL4
Organism: Mus musculus/domesticus
Length: 739  
Fragment?: false
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Protein
Q80WG0
Organism: Mus musculus/domesticus
Length: 240  
Fragment?: true
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Protein
A0A2I3BPV3
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: true
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Protein
Q3TXR4
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q3US24
Organism: Mus musculus/domesticus
Length: 739  
Fragment?: false
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Protein
A0A2R8VHY0
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
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Protein
Q3UKW6
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
Q3US63
Organism: Mus musculus/domesticus
Length: 739  
Fragment?: false
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Protein
Q3US19
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
Q3U2Y0
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q8C8Y1
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Protein
Q3V255
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
Q3V2C2
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: true
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Protein
Q52L79
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
Q3U0G5
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Publication
35092867 | J:322622
 
First Author: Han G
Year: 2022
Journal: Redox Biol
Title: Nrf2 expands the intracellular pool of the chaperone AHSP in a cellular model of β-thalassemia.
Volume: 50
Pages: 102239
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Publication
26176793 | J:260641
 
First Author: Iniaghe LO
Year: 2015
Journal: Neurobiol Dis
Title: Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage.
Volume: 82
Pages: 349-358
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Publication
37450596 | J:338613
First Author: Wang Y
Year: 2023
Journal: Sci Adv
Title: Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness.
Volume: 9
Issue: 28
Pages: eadd5479
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Publication
27060105 | J:239484
First Author: Zhang Y
Year: 2016
Journal: Biochem J
Title: Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity.
Volume: 473
Issue: 8
Pages: 961-1000
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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