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Search results 801 to 900 out of 1146 for Pkd1

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Type Details Score
Publication
31301888 | J:297556
First Author: Egli-Spichtig D
Year: 2019
Journal: Kidney Int
Title: Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation.
Volume: 96
Issue: 4
Pages: 890-905
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Publication
32238474 | J:328906
First Author: Viau A
Year: 2020
Journal: J Am Soc Nephrol
Title: Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease.
Volume: 31
Issue: 5
Pages: 1035-1049
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Publication
31601454 | J:297942
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
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Publication
25573755 | J:302798
First Author: Wang W
Year: 2015
Journal: FASEB J
Title: Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling.
Volume: 29
Issue: 4
Pages: 1551-63
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Publication
20215348 | J:158678
First Author: Tran U
Year: 2010
Journal: Development
Title: The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity.
Volume: 137
Issue: 7
Pages: 1107-16
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Publication
16311606 | J:182496
First Author: Li X
Year: 2005
Journal: Nat Cell Biol
Title: Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2.
Volume: 7
Issue: 12
Pages: 1202-12
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Publication
26110849 | J:233794
First Author: Zhou JX
Year: 2015
Journal: PLoS One
Title: TNFα signaling regulates cystic epithelial cell proliferation through Akt/mTOR and ERK/MAPK/Cdk2 mediated Id2 signaling.
Volume: 10
Issue: 6
Pages: e0131043
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Publication
26038530 | J:287777
First Author: Huang JL
Year: 2016
Journal: J Am Soc Nephrol
Title: Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases.
Volume: 27
Issue: 1
Pages: 69-77
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Publication
21041232 | J:166903
First Author: AbouAlaiwi WA
Year: 2011
Journal: Hum Mol Genet
Title: Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.
Volume: 20
Issue: 2
Pages: 354-67
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Publication
10547347 | J:59035
 
First Author: Müller U
Year: 1999
Journal: J Cell Sci
Title: Cell adhesion molecules and extracellular-matrix constituents in kidney development and disease.
Volume: 112 ( Pt 22)
Pages: 3855-67
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Publication
16805797 | J:110462
First Author: LopezJimenez ND
Year: 2006
Journal: J Neurochem
Title: Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.
Volume: 98
Issue: 1
Pages: 68-77
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Publication
29107072 | J:257473
First Author: Puri P
Year: 2018
Journal: Am J Pathol
Title: Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease.
Volume: 188
Issue: 1
Pages: 84-94
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Publication
14600027 | J:87130
First Author: Guay-Woodford LM
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Murine models of polycystic kidney disease: molecular and therapeutic insights.
Volume: 285
Issue: 6
Pages: F1034-49
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Publication
32182218 | J:306875
 
First Author: Lakhia R
Year: 2020
Journal: JCI Insight
Title: Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
Volume: 5
Issue: 7
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Publication
20375015 | J:164472
First Author: Yi T
Year: 2010
Journal: J Biol Chem
Title: Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression.
Volume: 285
Issue: 23
Pages: 17811-20
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Publication
31475747 | J:313370
First Author: Peña-Jimenez D
Year: 2019
Journal: EMBO J
Title: Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo.
Volume: 38
Issue: 19
Pages: e101688
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Publication
27272319 | J:233311
First Author: Grimes DT
Year: 2016
Journal: PLoS Genet
Title: Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.
Volume: 12
Issue: 6
Pages: e1006070
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Publication
31808745 | J:293098
   
First Author: Jafree DJ
Year: 2019
Journal: Elife
Title: Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease.
Volume: 8
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Publication
18172001 | J:132020
First Author: Makita R
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
Volume: 294
Issue: 3
Pages: F542-53
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Publication
22677559 | J:316665
First Author: Qin S
Year: 2012
Journal: J Am Soc Nephrol
Title: c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.
Volume: 23
Issue: 8
Pages: 1309-18
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Publication
16472605 | J:125042
First Author: Pierreux CE
Year: 2006
Journal: Gastroenterology
Title: The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.
Volume: 130
Issue: 2
Pages: 532-41
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Publication
27591083 | J:255143
First Author: Rasouly HM
Year: 2016
Journal: Kidney Int
Title: Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.
Volume: 90
Issue: 6
Pages: 1262-1273
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Publication
28154160 | J:246963
First Author: Badgandi HB
Year: 2017
Journal: J Cell Biol
Title: Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.
Volume: 216
Issue: 3
Pages: 743-760
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Publication
27002738 | J:231949
 
First Author: San Agustin JT
Year: 2016
Journal: Nat Commun
Title: Genetic link between renal birth defects and congenital heart disease.
Volume: 7
Pages: 11103
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Publication
37982452 | J:343798
 
First Author: Cheng T
Year: 2023
Journal: Development
Title: Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Volume: 150
Issue: 24
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Publication
27582005 | J:235788
First Author: Nagy II
Year: 2016
Journal: BMC Dev Biol
Title: Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.
Volume: 16
Issue: 1
Pages: 30
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Publication
16291790 | J:104377
First Author: Nakaya MA
Year: 2005
Journal: Development
Title: Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.
Volume: 132
Issue: 24
Pages: 5425-36
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Publication
17251353 | J:119488
First Author: Hossain Z
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
Volume: 104
Issue: 5
Pages: 1631-6
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Publication
19834762 | J:161879
First Author: Asai Y
Year: 2010
Journal: J Assoc Res Otolaryngol
Title: A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.
Volume: 11
Issue: 1
Pages: 27-37
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Publication
25715395 | J:220324
First Author: De Vas MG
Year: 2015
Journal: Development
Title: Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.
Volume: 142
Issue: 5
Pages: 871-82
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Publication
33737325 | J:306107
 
First Author: Niborski LL
Year: 2021
Journal: Dis Model Mech
Title: Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.
Volume: 14
Issue: 5
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Publication
16319116 | J:104891
First Author: Osafune K
Year: 2006
Journal: Development
Title: Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.
Volume: 133
Issue: 1
Pages: 151-61
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Publication
19322198 | J:148796
First Author: Lechner SG
Year: 2009
Journal: EMBO J
Title: Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.
Volume: 28
Issue: 10
Pages: 1479-91
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Publication
20843830 | J:166958
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
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Publication
25807483 | J:222159
First Author: Li Y
Year: 2015
Journal: Nature
Title: Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Volume: 521
Issue: 7553
Pages: 520-4
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Publication
- | J:175213
     
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)
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Publication
23375831 | J:237827
First Author: Gineste C
Year: 2013
Journal: Neuromuscul Disord
Title: In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Volume: 23
Issue: 4
Pages: 357-69
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Publication
27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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Publication
15582152 | J:102103
First Author: Jensen P
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A neurogenomics approach to gene expression analysis in the developing brain.
Volume: 132
Issue: 2
Pages: 116-27
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
29133434 | J:255684
First Author: Cen C
Year: 2018
Journal: J Neurosci
Title: PKD1 Promotes Functional Synapse Formation Coordinated with N-Cadherin in Hippocampus.
Volume: 38
Issue: 1
Pages: 183-199
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Publication
33521594 | J:306832
First Author: Fleming Martinez AK
Year: 2021
Journal: iScience
Title: Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells.
Volume: 24
Issue: 1
Pages: 102019
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Publication
26192751 | J:244762
First Author: Johnson KR
Year: 2015
Journal: PLoS One
Title: Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy.
Volume: 10
Issue: 7
Pages: e0132474
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Publication
28408623 | J:243667
First Author: Chang JK
Year: 2017
Journal: J Biol Chem
Title: Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization.
Volume: 292
Issue: 23
Pages: 9523-9539
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Publication
31591827 | J:295483
First Author: Khan S
Year: 2019
Journal: Physiol Rep
Title: A role for PKD1 in insulin secretion downstream of P2Y1 receptor activation in mouse and human islets.
Volume: 7
Issue: 19
Pages: e14250
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Publication
31517390 | J:299863
First Author: Li J
Year: 2020
Journal: J Cell Physiol
Title: Upregulated microRNA-31 inhibits oxidative stress-induced neuronal injury through the JAK/STAT3 pathway by binding to PKD1 in mice with ischemic stroke.
Volume: 235
Issue: 3
Pages: 2414-2428
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Allele
Tg(Pkd1*)39Mtru | MGI:5519083
Name: transgene insertion 39, Marie Trudel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Pkd1<tm1.1Fqi> | MGI:5470234
 
Name: polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Feng Qian
Allele Type: Targeted
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Publication
38449738 | J:345890
 
First Author: Ay M
Year: 2024
Journal: Front Neurosci
Title: Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease.
Volume: 18
Pages: 1356703
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Allele
Pkd1<em1Smoc> | MGI:7291670
Name: polycystin 1, transient receptor potential channel interacting; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Coding Gene
MGI:99879 | Prkd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Pkd1/Pkd1
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pkd1*)39Mtru/?
Background: involves: C57BL/6J * CBA/J
Zygosity: ot
Has Mutant Allele: true
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Publication
10469604 | -
First Author: Bateman A
Year: 1999
Journal: Curr Biol
Title: The PLAT domain: a new piece in the PKD1 puzzle.
Volume: 9
Issue: 16
Pages: R588-90
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Genotype
Genotype
Symbol: Gpsm1/Gpsm1 Pkd1/Pkd1
Background: involves: 129S6/SvEvTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd1/Pkd1<+> Tg(Pkd1*)39Mtru/?
Background: involves: 129/Sv * C57BL/6J * CBA/J * SJL
Zygosity: cx
Has Mutant Allele: true
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Interaction Experiment
Bhunia AK (2002)
Description: PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.
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Strain
MGI:6476028 | C57BL/6-Pkd1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Pkd1<tm1Gztn> | MGI:4437121
Name: polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Thomas Natoli
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Pkd1<tm1Bdgz> | MGI:3714781
 
Name: polycystin 1, transient receptor potential channel interacting; targeted mutation 1, William Dackowski
Allele Type: Targeted
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