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Search results 101 to 200 out of 379 for Shc1

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Type Details Score
Publication
20354186 | J:158964
First Author: Xiao D
Year: 2010
Journal: Cancer Res
Title: p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.
Volume: 70
Issue: 8
Pages: 3150-8
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Publication
20567235 | J:166275
First Author: Haga S
Year: 2010
Journal: Lab Invest
Title: p66(Shc) has a pivotal function in impaired liver regeneration in aged mice by a redox-dependent mechanism.
Volume: 90
Issue: 12
Pages: 1718-26
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Publication
24378437 | J:211960
 
First Author: Frijhoff J
Year: 2014
Journal: Free Radic Biol Med
Title: The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation.
Volume: 68
Pages: 268-77
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Publication
24845561 | J:222000
First Author: Kumar S
Year: 2014
Journal: Biochem Biophys Res Commun
Title: P66Shc mediates increased platelet activation and aggregation in hypercholesterolemia.
Volume: 449
Issue: 4
Pages: 496-501
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Publication
29453337 | J:263819
First Author: Minami Y
Year: 2018
Journal: Sci Rep
Title: p66Shc Signaling Mediates Diabetes-Related Cognitive Decline.
Volume: 8
Issue: 1
Pages: 3213
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Publication
29243276 | J:273906
First Author: Baldassini WA
Year: 2017
Journal: Cell Biochem Funct
Title: The influence of Shc proteins and high-fat diet on energy metabolism of mice.
Volume: 35
Issue: 8
Pages: 527-537
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Publication
33302436 | J:305099
 
First Author: Hirschhäuser C
Year: 2020
Journal: Int J Mol Sci
Title: Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy.
Volume: 21
Issue: 24
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Publication
25071152 | J:315544
First Author: Hudson J
Year: 2014
Journal: Mol Cell Biol
Title: p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.
Volume: 34
Issue: 19
Pages: 3689-701
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Publication
29636844 | J:313216
 
First Author: D'Agostino M
Year: 2018
Journal: Oxid Med Cell Longev
Title: Role of miR-200c in Myogenic Differentiation Impairment via p66Shc: Implication in Skeletal Muscle Regeneration of Dystrophic mdx Mice.
Volume: 2018
Pages: 4814696
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Publication
29051737 | J:311977
 
First Author: Boengler K
Year: 2017
Journal: Front Physiol
Title: Lack of Contribution of p66shc and Its Mitochondrial Translocation to Ischemia-Reperfusion Injury and Cardioprotection by Ischemic Preconditioning.
Volume: 8
Pages: 733
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Publication
24336818 | J:320939
First Author: Ramsey JJ
Year: 2014
Journal: J Gerontol A Biol Sci Med Sci
Title: The influence of Shc proteins on life span in mice.
Volume: 69
Issue: 10
Pages: 1177-85
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:4946246
Age: embryonic day 14.5
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:4946246
Age: embryonic day 14.5
Image: 1
Specimen Label: Muscle
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:4946246
Age: embryonic day 14.5
Image: 1
Specimen Label: Liver
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:4946246
Age: embryonic day 14.5
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:4946246
Age: embryonic day 14.5
Image: 1
Specimen Label: Skin
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4946246
Age: postnatal adult
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Female
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:4946246
Age: postnatal adult
Image: 1
Specimen Label: Muscle
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Female
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4946246
Age: postnatal adult
Image: 1
Specimen Label: Liver
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Female
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4946246
Age: postnatal adult
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:4944253
Assay Type: RT-PCR
Annotation Date: 2011-04-12
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:4946246
Age: postnatal adult
Image: 1
Specimen Label: Skin
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: Northern blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:6159729
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: Northern blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6159729
Age: embryonic day 15.5
Image: 1
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: Northern blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6159729
Age: postnatal day 1
Image: 1
Specimen Label: P1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: Northern blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6159729
Age: postnatal day 7
Image: 1
Specimen Label: P7
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: Northern blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6159729
Age: postnatal day 14
Image: 1
Specimen Label: P14
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: Northern blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6159729
Age: postnatal week 10
Image: 1
Specimen Label: 10W
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6159703
Assay Type: Western blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:6159733
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6159703
Assay Type: Western blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6159733
Age: embryonic day 15.5
Image: 1
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6159703
Assay Type: Western blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6159733
Age: postnatal day 1
Image: 1
Specimen Label: P1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6159703
Assay Type: Western blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6159733
Age: postnatal day 7
Image: 1
Specimen Label: P7
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:6159703
Assay Type: Western blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6159733
Age: postnatal day 14
Image: 1
Specimen Label: P14
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6159703
Assay Type: Western blot
Annotation Date: 2018-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6159733
Age: postnatal week 10
Image: 1
Specimen Label: 10W
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7328567
Assay Type: RT-PCR
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:7328568
Age: embryonic day 0.5
Specimen Label: Zygote
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7328567
Assay Type: RT-PCR
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:7328568
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7328567
Assay Type: RT-PCR
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:7328568
Age: embryonic day 2.5
Specimen Label: 8-cell
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7328567
Assay Type: RT-PCR
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:7328568
Age: embryonic day 3.5
Specimen Label: Blastocyst
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7328571
Assay Type: Western blot
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:7328574
Age: embryonic day 0.5
Specimen Label: Zygote
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7328571
Assay Type: Western blot
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:7328574
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Probe: MGI:7328571
Assay Type: Western blot
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:7328574
Age: embryonic day 2.5
Specimen Label: 8-cell
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
     
Probe: MGI:7328571
Assay Type: Western blot
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:7328574
Age: embryonic day 3.5
Specimen Label: Blastocyst
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:7328575
Age: embryonic day 2.0
Note: Expression is throughout the cytoplasm.
Specimen Label: 2C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1721324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 E16.5
Note: Expression was detected in populations of hypertrophic chondrocytes throughout the embryo.
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Not Specified
Stage: TS01
Assay Id: MGI:7328575
Age: embryonic day 0.5
Note: Expression is throughout the cytoplasm.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4428661
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526628
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 E16.5
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 Skin
Specimen Label: 3 Skin
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:7328575
Age: embryonic day 2.5
Note: Expression is throughout the cytoplasm.
Specimen Label: 2D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4867011
Assay Type: RNA in situ
Annotation Date: 2011-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666819
Stage: TS19
Assay Id: MGI:4867013
Age: embryonic day 11.5
Specimen Label: 3G
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4867011
Assay Type: RNA in situ
Annotation Date: 2011-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666821
Stage: TS21
Assay Id: MGI:4867013
Age: embryonic day 13.5
Specimen Label: 3I
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4946256
Age: embryonic day 12.5
Image: 3 E12.5
Specimen Label: 3 E12.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 E16.5
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 Heart
Specimen Label: 3 Heart
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 E16.5
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 Liver
Specimen Label: 3 Liver
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 E16.5
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 Gut
Specimen Label: 3 Gut
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1800824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 E16.5
Note: Expression was detected in the hypertrophic chondrocytes and chondrocyte-like cells contained within the nucleus pulposus in the central region of the intervertebral discs.
Specimen Label: 3 E16.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1800824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4946256
Age: embryonic day 16.5
Image: 3 Bone
Note: Expression was detected in the hypertrophic chondrocytes and chondrocyte-like cells contained within the nucleus pulposus in the central region of the intervertebral discs.
Specimen Label: 3 Bone
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:7328575
Age: embryonic day 3.0
Note: Expression is at the apical cell periphery.
Specimen Label: 2E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4428661
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526628
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7328575
Age: embryonic day 3.5
Note: Expression is at the cell periphery.
Specimen Label: 2F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:7328575
Age: embryonic day 1.0
Note: Expression is throughout the cytoplasm.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4946256
Age: embryonic day 12.5
Image: 3 E12.5
Specimen Label: 3 E12.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6159694
Assay Type: RNA in situ
Annotation Date: 2018-06-06
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6159758
Age: postnatal week 10
Note: Authors state that expression was negligible in the various regions of the brain.
Specimen Label: not shown
Specimen Num: 1
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Publication
10086341 | J:53892
First Author: Schmandt R
Year: 1999
Journal: Oncogene
Title: Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells.
Volume: 18
Issue: 10
Pages: 1867-79
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Publication
32345753 | J:293274
First Author: Tedesco S
Year: 2020
Journal: Diabetes
Title: Pharmacologic PPAR-γ Activation Reprograms Bone Marrow Macrophages and Partially Rescues HSPC Mobilization in Human and Murine Diabetes.
Volume: 69
Issue: 7
Pages: 1562-1572
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Publication
27059956 | J:235036
First Author: Tomilov A
Year: 2016
Journal: J Biol Chem
Title: p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.
Volume: 291
Issue: 24
Pages: 12575-85
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Publication
11756549 | J:76630
First Author: Feng Q
Year: 2002
Journal: Mol Cell Biol
Title: Identification and functional characterization of the p66/p68 components of the MeCP1 complex.
Volume: 22
Issue: 2
Pages: 536-46
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Publication
18273058 | J:133325
First Author: Ursini-Siegel J
Year: 2008
Journal: EMBO J
Title: ShcA signalling is essential for tumour progression in mouse models of human breast cancer.
Volume: 27
Issue: 6
Pages: 910-20
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Publication
22277070 | J:184240
First Author: Su KG
Year: 2012
Journal: Eur J Neurosci
Title: Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis.
Volume: 35
Issue: 4
Pages: 562-71
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Publication
33119054 | J:322336
First Author: Gierhardt M
Year: 2022
Journal: Cardiovasc Res
Title: Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone.
Volume: 118
Issue: 1
Pages: 305-315
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Publication
30207172 | J:283969
First Author: Vashistha H
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent.
Volume: 315
Issue: 6
Pages: F1833-F1842
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Publication
18838380 | J:143610
First Author: Berniakovich I
Year: 2008
Journal: J Biol Chem
Title: p66Shc-generated oxidative signal promotes fat accumulation.
Volume: 283
Issue: 49
Pages: 34283-93
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Publication
27590316 | J:305385
First Author: Wolter J
Year: 2016
Journal: J Thromb Haemost
Title: Thrombomodulin-dependent protein C activation is required for mitochondrial function and myelination in the central nervous system.
Volume: 14
Issue: 11
Pages: 2212-2226
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Publication
20624962 | J:162570
First Author: Ranieri SC
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance.
Volume: 107
Issue: 30
Pages: 13420-5
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Publication
26122877 | J:226448
First Author: Ciciliot S
Year: 2015
Journal: Diabetologia
Title: p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans.
Volume: 58
Issue: 10
Pages: 2352-60
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Publication
36716673 | J:341705
 
First Author: Jiang T
Year: 2023
Journal: Redox Biol
Title: SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Volume: 60
Pages: 102615
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Publication
14502564 | J:85624
First Author: Gagnon A
Year: 2003
Journal: J Cell Physiol
Title: Regulation of endogenous SH2 domain-containing inositol 5-phosphatase (SHIP2) in 3T3-L1 and human preadipocytes.
Volume: 197
Issue: 2
Pages: 243-50
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Publication
11259577 | J:277874
First Author: Valverde AM
Year: 2001
Journal: Mol Cell Biol
Title: Association of insulin receptor substrate 1 (IRS-1) y895 with Grb-2 mediates the insulin signaling involved in IRS-1-deficient brown adipocyte mitogenesis.
Volume: 21
Issue: 7
Pages: 2269-80
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Publication
7529871 | J:200360
First Author: Ravichandran KS
Year: 1995
Journal: Mol Cell Biol
Title: Interaction of Shc with Grb2 regulates association of Grb2 with mSOS.
Volume: 15
Issue: 2
Pages: 593-600
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Publication
11088019 | J:66125
First Author: Luzi L
Year: 2000
Journal: Curr Opin Genet Dev
Title: Evolution of Shc functions from nematode to human.
Volume: 10
Issue: 6
Pages: 668-74
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Publication
8101647 | J:13198
First Author: Segatto O
Year: 1993
Journal: Oncogene
Title: Shc products are substrates of erbB-2 kinase.
Volume: 8
Issue: 8
Pages: 2105-12
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Publication
25147340 | J:318252
First Author: Vikram A
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.
Volume: 34
Issue: 10
Pages: 2301-9
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Publication
27385725 | J:321237
First Author: Edwards NA
Year: 2016
Journal: Mol Hum Reprod
Title: P66Shc, a key regulator of metabolism and mitochondrial ROS production, is dysregulated by mouse embryo culture.
Volume: 22
Issue: 9
Pages: 634-47
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Publication
10068665 | J:127946
First Author: Lucas DM
Year: 1999
Journal: Blood
Title: A novel spliced form of SH2-containing inositol phosphatase is expressed during myeloid development.
Volume: 93
Issue: 6
Pages: 1922-33
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Publication
7798194 | J:39401
First Author: Blaikie P
Year: 1994
Journal: J Biol Chem
Title: A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.
Volume: 269
Issue: 51
Pages: 32031-4
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Publication
21148430 | J:183507
First Author: Vanderlaan RD
Year: 2011
Journal: Circ Res
Title: The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.
Volume: 108
Issue: 2
Pages: 184-93
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Publication
12032825 | J:94749
First Author: Trinei M
Year: 2002
Journal: Oncogene
Title: A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.
Volume: 21
Issue: 24
Pages: 3872-8
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Publication
23267072 | J:192597
First Author: Bock F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc.
Volume: 110
Issue: 2
Pages: 648-53
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Publication
23448364 | J:216110
First Author: Gambino V
Year: 2013
Journal: Aging Cell
Title: Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging.
Volume: 12
Issue: 3
Pages: 435-45
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Publication
23019230 | J:190320
First Author: Vashistha H
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.
Volume: 303
Issue: 12
Pages: F1629-40
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Publication
31207271 | J:279032
 
First Author: Jiang W
Year: 2019
Journal: Mol Cell Endocrinol
Title: Klotho inhibits PKCα/p66SHC-mediated podocyte injury in diabetic nephropathy.
Volume: 494
Pages: 110490
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Publication
20075861 | J:200379
First Author: Smith MJ
Year: 2010
Journal: EMBO J
Title: The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.
Volume: 29
Issue: 5
Pages: 884-96
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Publication
11707404 | J:73038
First Author: Ong SH
Year: 2001
Journal: EMBO J
Title: ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.
Volume: 20
Issue: 22
Pages: 6327-36
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Publication
21117147 | J:166965
First Author: Hawley SP
Year: 2011
Journal: Dev Dyn
Title: Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development.
Volume: 240
Issue: 1
Pages: 221-31
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Publication
23769981 | J:204123
First Author: Ito H
Year: 2013
Journal: Biochim Biophys Acta
Title: MAGI-1 acts as a scaffolding molecule for NGF receptor-mediated signaling pathway.
Volume: 1833
Issue: 10
Pages: 2302-10
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Publication
10486198 | J:304002
First Author: Yuen EC
Year: 1999
Journal: Exp Neurol
Title: Early BDNF, NT-3, and NT-4 signaling events.
Volume: 159
Issue: 1
Pages: 297-308
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Publication
23832324 | J:315504
First Author: Xiong Y
Year: 2013
Journal: J Am Heart Assoc
Title: Arginase-II induces vascular smooth muscle cell senescence and apoptosis through p66Shc and p53 independently of its l-arginine ureahydrolase activity: implications for atherosclerotic plaque vulnerability.
Volume: 2
Issue: 4
Pages: e000096
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Publication
9872323 | J:52472
First Author: Liu SK
Year: 1998
Journal: Oncogene
Title: Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc.
Volume: 17
Issue: 24
Pages: 3073-82
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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