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Search results 201 to 235 out of 235 for Nab1

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0.018s
Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein Domain
Type: Domain
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This C-terminal region is found only in the Nab1 subfamily.
Protein
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 485  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
Publication
First Author: Swirnoff AH
Year: 1998
Journal: Mol Cell Biol
Title: Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain.
Volume: 18
Issue: 1
Pages: 512-24
Protein Domain
Type: Domain
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This entry represents the N-terminal NAB domain, which interacts with the EGR1 inhibitory domain (R1) []. It may also mediate multimerisation.
Protein
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
Publication
First Author: Sevetson BR
Year: 2000
Journal: J Biol Chem
Title: A novel activation function for NAB proteins in EGR-dependent transcription of the luteinizing hormone beta gene.
Volume: 275
Issue: 13
Pages: 9749-57
Protein
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
Publication
First Author: Terriente FĂ©lix J
Year: 2007
Journal: Development
Title: Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development.
Volume: 134
Issue: 10
Pages: 1845-52
Protein Domain
Type: Domain
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This entry represents a NAB domain 2 of the protein. It is necessary for transcriptional repression by the Nab proteins []. It is also required for transcription activation by Nab proteins at Nab-activated promoters [].
Protein Domain
Type: Homologous_superfamily
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This entry represents a NAB domain 2 of the protein. It is necessary for transcriptional repression by the Nab proteins []. It is also required for transcription activation by Nab proteins at Nab-activated promoters [].
Protein Domain
Type: Family
Description: Proteins in this family are transcriptional regulators, including Nab (NGFI-A-binding protein) from Drosophila and Nab1/2 from mammals. Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. Drosophila Nab controls the activity of zinc-finger transcription factors, such as Squeeze and Rotund, in Drosophila development [].
Protein
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
Publication
First Author: Kayam G
Year: 2013
Journal: Development
Title: A novel role for Pax6 in the segmental organization of the hindbrain.
Volume: 140
Issue: 10
Pages: 2190-202
Protein
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
Publication
First Author: Abou-Khalil B
Year: 2001
Journal: Neurology
Title: Partial and generalized epilepsy with febrile seizures plus and a novel SCN1A mutation.
Volume: 57
Issue: 12
Pages: 2265-72
Protein Domain
Type: Family
Description: Voltage-dependent sodium channels are transmembrane (TM) proteins responsible for the depolarising phase of the action potential in mostelectrically excitable cells []. They may exist in 3 states []: the resting state, where the channel is closed; the activated state, where the channel is open; and the inactivated state, where the channel is closed and refractory to opening. Several different structurally and functionally distinct isoforms are found in mammals, coded for by a multigene family, these being responsible for the different types of sodium ion currents found in excitable tissues.There are nine pore-forming alpha subunit of voltage-gated sodium channels consisting of four membrane-embedded homologous domains (I-IV), each consisting of six α-helical segments (S1-S6), three cytoplasmic loops connecting the domains, and a cytoplasmic C-terminal tail. The S6 segments of the four domains form the inner surface of the pore, while the S4 segments bear clusters of basic residues that constitute the channel's voltage sensors [, , ].The SCN1A gene encodes the NaB1 channel and is particularly expressed inthe brain, but is also found in a variety of other tissues, ranging from theretina to the olfactory bulb. Epilepsy, a disorder of neuronalhyperexcitability, has been associated with altered kinetics of SCN1A, aswell as delayed inactivation of SCN2A [].This entry represents the alpha 1 subunits of the voltage-gated Na+ channel superfamily. For entries containing other members of this superfamily see , , .
Protein
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2009  
Fragment?: false
Publication
First Author: Noda M
Year: 1984
Journal: Nature
Title: Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence.
Volume: 312
Issue: 5990
Pages: 121-7
Publication
First Author: George AL Jr
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene family.
Volume: 89
Issue: 11
Pages: 4893-7
Publication
First Author: Goldfarb M
Year: 2012
Journal: Cell Mol Life Sci
Title: Voltage-gated sodium channel-associated proteins and alternative mechanisms of inactivation and block.
Volume: 69
Issue: 7
Pages: 1067-76
Publication  
First Author: Kaplan DI
Year: 2016
Journal: Cold Spring Harb Perspect Med
Title: Role of Sodium Channels in Epilepsy.
Volume: 6
Issue: 6
Publication
First Author: Sato C
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Proposed tertiary structure of the sodium channel.
Volume: 186
Issue: 2
Pages: 1158-67
Publication
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
Publication  
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
Publication
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
Publication
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6