The adaptor protein linker activator of T-cells 2 (LAT2), also called non-T-cell activation linker (NTAL), linker activator for B-cells (LAB) or Williams Beuren Syndrome critical region 5 (WBSCR5), is expressed in various myeloid and lymphoid cells []. Given the wide expression pattern, it may modulate signalling in most types of leukocytes []. It has been shown to be involved in immunoreceptor signaling [], B cell activation [], negative regulation of T cell activation [], and regulation of mast cell physiology [].
