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Search results 1 to 100 out of 312 for Tbk1

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Category: Publication
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Type Details Score
Publication
23746807 | J:245352
First Author: Shu C
Year: 2013
Journal: Structure
Title: Structural insights into the functions of TBK1 in innate antimicrobial immunity.
Volume: 21
Issue: 7
Pages: 1137-48
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Publication
31792381 | J:282979
First Author: Zhu L
Year: 2019
Journal: Nat Cell Biol
Title: TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.
Volume: 21
Issue: 12
Pages: 1604-1614
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Publication
10990461 | J:91653
First Author: Bonnard M
Year: 2000
Journal: EMBO J
Title: Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription.
Volume: 19
Issue: 18
Pages: 4976-85
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Publication
14679297 | J:87323
First Author: McWhirter SM
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
Volume: 101
Issue: 1
Pages: 233-8
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Publication
35074921 | J:320662
 
First Author: Gao T
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Myeloid cell TBK1 restricts inflammatory responses.
Volume: 119
Issue: 4
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Publication
10581243 | J:66310
First Author: Pomerantz JL
Year: 1999
Journal: EMBO J
Title: NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase.
Volume: 18
Issue: 23
Pages: 6694-704
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Publication
15661922 | J:96405
First Author: O'Connell RM
Year: 2005
Journal: J Immunol
Title: Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1.
Volume: 174
Issue: 3
Pages: 1602-7
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Publication
34678655 | J:328005
 
First Author: Liu Q
Year: 2021
Journal: Redox Biol
Title: GSNOR facilitates antiviral innate immunity by restricting TBK1 cysteine S-nitrosation.
Volume: 47
Pages: 102172
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Publication
21329883 | J:170850
First Author: Ou YH
Year: 2011
Journal: Mol Cell
Title: TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Volume: 41
Issue: 4
Pages: 458-70
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Publication
30938713 | J:308939
   
First Author: Cruz VH
Year: 2019
Journal: JCI Insight
Title: Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer.
Volume: 5
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Publication
30420664 | J:268450
First Author: Lafont E
Year: 2018
Journal: Nat Cell Biol
Title: TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.
Volume: 20
Issue: 12
Pages: 1389-1399
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Publication
30290124 | J:288293
First Author: Hagan RS
Year: 2019
Journal: Am J Respir Cell Mol Biol
Title: Myeloid TBK1 Signaling Contributes to the Immune Response to Influenza.
Volume: 60
Issue: 3
Pages: 335-345
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Publication
29935921 | J:341476
 
First Author: Cruz VH
Year: 2018
Journal: Mol Metab
Title: Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.
Volume: 16
Pages: 139-149
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Publication
29425491 | J:260658
First Author: Zhao P
Year: 2018
Journal: Cell
Title: TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.
Volume: 172
Issue: 4
Pages: 731-743.e12
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Publication
37352355 | J:338425
First Author: Hu Z
Year: 2023
Journal: Sci Adv
Title: VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
Volume: 9
Issue: 25
Pages: eadg2339
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Publication
33038415 | J:301266
 
First Author: Sieverding K
Year: 2021
Journal: Exp Neurol
Title: Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
Volume: 335
Pages: 113496
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Publication
25606824 | J:219715
 
First Author: Yu J
Year: 2015
Journal: Nat Commun
Title: Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation.
Volume: 6
Pages: 6074
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Publication
28325821 | J:260011
 
First Author: Uhm M
Year: 2017
Journal: Sci Signal
Title: Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking.
Volume: 10
Issue: 471
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Publication
30146158 | J:311882
First Author: Xu D
Year: 2018
Journal: Cell
Title: TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.
Volume: 174
Issue: 6
Pages: 1477-1491.e19
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Publication
32745468 | J:298232
First Author: Yang JY
Year: 2020
Journal: Gastroenterology
Title: Intestinal Epithelial TBK1 Prevents Differentiation of T-helper 17 Cells and Tumorigenesis in Mice.
Volume: 159
Issue: 5
Pages: 1793-1806
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Publication
27753621 | J:238732
First Author: Gu M
Year: 2016
Journal: EMBO J
Title: RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity.
Volume: 35
Issue: 23
Pages: 2553-2565
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Publication
34901991 | J:320021
 
First Author: Li T
Year: 2022
Journal: J Exp Med
Title: TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance.
Volume: 219
Issue: 1
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Publication
31039129 | J:290351
First Author: Duan W
Year: 2019
Journal: Aging (Albany NY)
Title: Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice.
Volume: 11
Issue: 8
Pages: 2457-2476
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Publication
28356390 | J:241855
First Author: Xiao Y
Year: 2017
Journal: J Exp Med
Title: The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity.
Volume: 214
Issue: 5
Pages: 1493-1507
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Publication
34245780 | J:328512
First Author: Tooley AS
Year: 2021
Journal: J Biol Chem
Title: The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt.
Volume: 297
Issue: 2
Pages: 100942
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Publication
29150432 | J:257513
First Author: Bodur C
Year: 2018
Journal: EMBO J
Title: The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.
Volume: 37
Issue: 1
Pages: 19-38
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Publication
31616416 | J:281843
 
First Author: Ozasa K
Year: 2019
Journal: Front Immunol
Title: Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor.
Volume: 10
Pages: 2212
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Publication
33164878 | J:313280
First Author: Gao B
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy.
Volume: 1867
Issue: 1
Pages: 165997
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Publication
23794264 | J:315252
First Author: Sun Q
Year: 2014
Journal: J Bone Miner Res
Title: TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.
Volume: 29
Issue: 1
Pages: 90-102
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Publication
23023393 | J:188560
First Author: Jin J
Year: 2012
Journal: Nat Immunol
Title: The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.
Volume: 13
Issue: 11
Pages: 1101-9
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Publication
32268090 | J:314406
First Author: Balka KR
Year: 2020
Journal: Cell Rep
Title: TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Volume: 31
Issue: 1
Pages: 107492
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Publication
34518217 | J:310703
 
First Author: Fischer FA
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.
Volume: 118
Issue: 38
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Publication
33785602 | J:304755
 
First Author: Yum S
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections.
Volume: 118
Issue: 14
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Publication
21204785 | J:169474
First Author: Smith H
Year: 2011
Journal: Biochem J
Title: The role of TBK1 and IKKε in the expression and activation of Pellino 1.
Volume: 434
Issue: 3
Pages: 537-48
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28159912 | J:246386
First Author: Bakshi S
Year: 2017
Journal: Biochem J
Title: Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β.
Volume: 474
Issue: 7
Pages: 1163-1174
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Publication
28069950 | J:239522
First Author: Hasan M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.
Volume: 114
Issue: 4
Pages: 746-751
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33326766 | J:305479
First Author: Wang Y
Year: 2020
Journal: Immunity
Title: Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
Volume: 53
Issue: 6
Pages: 1168-1181.e7
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20651301 | J:166476
First Author: Marchlik E
Year: 2010
Journal: J Leukoc Biol
Title: Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.
Volume: 88
Issue: 6
Pages: 1171-80
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Publication
28049762 | J:259208
 
First Author: Li X
Year: 2017
Journal: Sci Signal
Title: The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection.
Volume: 10
Issue: 460
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Publication
32220666 | J:286396
     
First Author: Gerbino V
Year: 2020
Journal: Neuron
Title: The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.
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Publication
31400857 | J:291228
First Author: Wang YY
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Sting is a critical regulator of spinal cord injury by regulating microglial inflammation via interacting with TBK1 in mice.
Volume: 517
Issue: 4
Pages: 741-748
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Publication
28954889 | J:251615
First Author: Ge M
Year: 2017
Journal: J Immunol
Title: HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.
Volume: 199
Issue: 9
Pages: 3280-3292
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Publication
34903812 | J:320019
First Author: Liu H
Year: 2021
Journal: Sci Rep
Title: Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation.
Volume: 11
Issue: 1
Pages: 23907
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Publication
23610142 | J:204786
First Author: Fukasaka M
Year: 2013
Journal: J Immunol
Title: Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation.
Volume: 190
Issue: 11
Pages: 5702-11
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15210742 | J:91363
First Author: Hemmi H
Year: 2004
Journal: J Exp Med
Title: The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection.
Volume: 199
Issue: 12
Pages: 1641-50
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18583960 | J:200396
First Author: Soulat D
Year: 2008
Journal: EMBO J
Title: The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response.
Volume: 27
Issue: 15
Pages: 2135-46
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30635357 | J:273057
First Author: Brenner D
Year: 2019
Journal: J Exp Med
Title: Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
Volume: 216
Issue: 2
Pages: 267-278
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27692986 | J:248785
First Author: Lin M
Year: 2016
Journal: Mol Cell
Title: USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome.
Volume: 64
Issue: 2
Pages: 267-281
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21074459 | J:166835
First Author: Tsuchida T
Year: 2010
Journal: Immunity
Title: The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA.
Volume: 33
Issue: 5
Pages: 765-76
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21617041 | J:222675
First Author: Wild P
Year: 2011
Journal: Science
Title: Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth.
Volume: 333
Issue: 6039
Pages: 228-33
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32814047 | J:306461
First Author: Huang L
Year: 2020
Journal: Cell Rep
Title: Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.
Volume: 32
Issue: 7
Pages: 108044
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17468758 | J:122421
First Author: Zhao T
Year: 2007
Journal: Nat Immunol
Title: The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways.
Volume: 8
Issue: 6
Pages: 592-600
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17056502 | J:140538
First Author: Matsui K
Year: 2006
Journal: J Immunol
Title: Cutting edge: Role of TANK-binding kinase 1 and inducible IkappaB kinase in IFN responses against viruses in innate immune cells.
Volume: 177
Issue: 9
Pages: 5785-9
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22945920 | J:219064
First Author: Zhang M
Year: 2012
Journal: J Exp Med
Title: TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1.
Volume: 209
Issue: 10
Pages: 1703-11
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Publication
33152322 | J:300240
First Author: Huh JY
Year: 2020
Journal: Cell Metab
Title: TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation.
Volume: 32
Issue: 6
Pages: 1012-1027.e7
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Publication
33171123 | J:300169
First Author: Chen S
Year: 2020
Journal: Mol Cell
Title: TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology.
Volume: 80
Issue: 5
Pages: 810-827.e7
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35172162 | J:320434
First Author: Chen J
Year: 2022
Journal: Cell Rep
Title: TBK1-METTL3 axis facilitates antiviral immunity.
Volume: 38
Issue: 7
Pages: 110373
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28025332 | J:241433
First Author: Fingert JH
Year: 2017
Journal: Hum Mol Genet
Title: Transgenic TBK1 mice have features of normal tension glaucoma.
Volume: 26
Issue: 1
Pages: 124-132
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24560620 | J:209896
First Author: Zhang L
Year: 2014
Journal: Immunity
Title: NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
Volume: 40
Issue: 3
Pages: 329-41
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23142775 | J:200472
First Author: Parvatiyar K
Year: 2012
Journal: Nat Immunol
Title: The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.
Volume: 13
Issue: 12
Pages: 1155-61
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25815785 | J:246454
First Author: Li Z
Year: 2015
Journal: PLoS Pathog
Title: PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation.
Volume: 11
Issue: 3
Pages: e1004783
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21270402 | J:169392
First Author: Da Q
Year: 2011
Journal: J Immunol
Title: TANK-binding kinase 1 attenuates PTAP-dependent retroviral budding through targeting endosomal sorting complex required for transport-I.
Volume: 186
Issue: 5
Pages: 3023-30
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25997745 | J:318263
 
First Author: Möser CV
Year: 2015
Journal: J Neuroinflammation
Title: TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes.
Volume: 12
Pages: 100
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Publication
27135603 | J:257322
First Author: Pedros C
Year: 2016
Journal: Nat Immunol
Title: A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.
Volume: 17
Issue: 7
Pages: 825-33
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Publication
37967220 | J:342970
First Author: Watanabe S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Mitochondria-associated membrane collapse impairs TBK1-mediated proteostatic stress response in ALS.
Volume: 120
Issue: 47
Pages: e2315347120
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18467330 | J:138116
First Author: Zhang M
Year: 2008
Journal: J Biol Chem
Title: Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
Volume: 283
Issue: 27
Pages: 18621-6
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18665841 | J:161102
First Author: Radtke AL
Year: 2008
Journal: Cell Microbiol
Title: Homeostatic maintenance of pathogen-containing vacuoles requires TBK1-dependent regulation of aquaporin-1.
Volume: 10
Issue: 11
Pages: 2197-207
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22000020 | J:177502
First Author: Chen H
Year: 2011
Journal: Cell
Title: Activation of STAT6 by STING is critical for antiviral innate immunity.
Volume: 147
Issue: 2
Pages: 436-46
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16286919 | J:112953
First Author: Ishii KJ
Year: 2006
Journal: Nat Immunol
Title: A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.
Volume: 7
Issue: 1
Pages: 40-8
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Publication
33608556 | J:303642
First Author: Gao P
Year: 2021
Journal: Nat Commun
Title: E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Volume: 12
Issue: 1
Pages: 1194
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23160154 | J:191073
First Author: Hasan M
Year: 2013
Journal: Nat Immunol
Title: Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes.
Volume: 14
Issue: 1
Pages: 61-71
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22252317 | J:183707
First Author: Farlik M
Year: 2012
Journal: Mol Cell Biol
Title: Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.
Volume: 32
Issue: 6
Pages: 1032-43
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32900826 | J:305018
 
First Author: Ouali Alami N
Year: 2020
Journal: Life Sci Alliance
Title: Multiplexed chemogenetics in astrocytes and motoneurons restore blood-spinal cord barrier in ALS.
Volume: 3
Issue: 11
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15210743 | J:120402
First Author: Perry AK
Year: 2004
Journal: J Exp Med
Title: Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection.
Volume: 199
Issue: 12
Pages: 1651-8
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23396947 | J:193597
First Author: Bruni D
Year: 2013
Journal: J Immunol
Title: A novel IRAK1-IKKε signaling axis limits the activation of TAK1-IKKβ downstream of TLR3.
Volume: 190
Issue: 6
Pages: 2844-56
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33741962 | J:303828
First Author: Zhang Y
Year: 2021
Journal: Nat Commun
Title: Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1.
Volume: 12
Issue: 1
Pages: 1731
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19483718 | J:150138
First Author: Wang C
Year: 2009
Journal: Nat Immunol
Title: The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon.
Volume: 10
Issue: 7
Pages: 744-52
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27043414 | J:256715
First Author: Wang F
Year: 2016
Journal: Nat Immunol
Title: S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.
Volume: 17
Issue: 5
Pages: 514-522
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27249321 | J:239911
 
First Author: Deng KQ
Year: 2016
Journal: Nat Commun
Title: Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy.
Volume: 7
Pages: 11432
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22007846 | J:179219
First Author: Goh ET
Year: 2012
Journal: Biochem J
Title: Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system.
Volume: 441
Issue: 1
Pages: 339-46
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20100929 | J:159662
First Author: Gabhann JN
Year: 2010
Journal: J Immunol
Title: Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production.
Volume: 184
Issue: 5
Pages: 2314-20
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Publication
24696485 | J:236952
First Author: Kang HR
Year: 2014
Journal: J Virol
Title: Murine gammaherpesvirus 68 encoding open reading frame 11 targets TANK binding kinase 1 to negatively regulate the host type I interferon response.
Volume: 88
Issue: 12
Pages: 6832-46
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34646390 | J:320971
First Author: Wang Y
Year: 2021
Journal: Theranostics
Title: A novel lncRNA linc-AhRA negatively regulates innate antiviral response in murine microglia upon neurotropic herpesvirus infection.
Volume: 11
Issue: 19
Pages: 9623-9651
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21820332 | J:175845
First Author: Sharma S
Year: 2011
Journal: Immunity
Title: Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Volume: 35
Issue: 2
Pages: 194-207
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Publication
22203995 | J:179973
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