Type |
Details |
Score |
Publication |
First Author: |
Harlow L |
Year: |
2012 |
Journal: |
Innate Immun |
Title: |
Characterization of TLR4-mediated auto-antibody production in a mouse model of histidyl-tRNA synthetase-induced myositis. |
Volume: |
18 |
Issue: |
6 |
Pages: |
876-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCrory EH |
Year: |
2022 |
Journal: |
Biochem J |
Title: |
Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12. |
Volume: |
479 |
Issue: |
23 |
Pages: |
2419-2431 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varodayan FP |
Year: |
2023 |
Journal: |
Brain Behav Immun |
Title: |
Chronic ethanol induces a pro-inflammatory switch in interleukin-1β regulation of GABAergic signaling in the medial prefrontal cortex of male mice. |
Volume: |
110 |
|
Pages: |
125-139 |
|
•
•
•
•
•
|
Publication |
First Author: |
Holloway KN |
Year: |
2023 |
Journal: |
Cells |
Title: |
Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling. |
Volume: |
12 |
Issue: |
16 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dutta D |
Year: |
2023 |
Journal: |
J Clin Invest |
Title: |
Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models. |
Volume: |
133 |
Issue: |
18 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
70
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Reed JC |
Year: |
2004 |
Journal: |
Sci STKE |
Title: |
The domains of apoptosis: a genomics perspective. |
Volume: |
2004 |
Issue: |
239 |
Pages: |
re9 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1862
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
521
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3898
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
310
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
518
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
310
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
881
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1887
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
838
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
518
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1098
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1174
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
508
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
145
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1878
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
838
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2871
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
961
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1098
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1848
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3926
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
502
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
556
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1001
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1883
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1157
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1862
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3900
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1907
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
459
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1863
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
480
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
978
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1852
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber CH |
Year: |
2001 |
Journal: |
Trends Biochem Sci |
Title: |
The death domain superfamily: a tale of two interfaces? |
Volume: |
26 |
Issue: |
8 |
Pages: |
475-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barboza R |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Endotoxin Exposure during Sensitization to Blomia tropicalis Allergens Shifts TH2 Immunity Towards a TH17-Mediated Airway Neutrophilic Inflammation: Role of TLR4 and TLR2. |
Volume: |
8 |
Issue: |
6 |
Pages: |
e67115 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kerur N |
Year: |
2013 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy. |
Volume: |
54 |
Issue: |
12 |
Pages: |
7395-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai T |
Year: |
2019 |
Journal: |
J Allergy Clin Immunol |
Title: |
IL-17-producing ST2+ group 2 innate lymphoid cells play a pathogenic role in lung inflammation. |
Volume: |
143 |
Issue: |
1 |
Pages: |
229-244.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duan Y |
Year: |
2019 |
Journal: |
Circ Res |
Title: |
Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency. |
Volume: |
125 |
Issue: |
11 |
Pages: |
969-988 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones CL |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
TLR2 signaling contributes to rapid inflammasome activation during F. novicida infection. |
Volume: |
6 |
Issue: |
6 |
Pages: |
e20609 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kong X |
Year: |
2011 |
Journal: |
Am J Respir Crit Care Med |
Title: |
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. |
Volume: |
184 |
Issue: |
8 |
Pages: |
928-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yin YW |
Year: |
2014 |
Journal: |
Cell Death Dis |
Title: |
TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression. |
Volume: |
5 |
|
Pages: |
e1574 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao X |
Year: |
2017 |
Journal: |
J Neuroimmunol |
Title: |
TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice. |
Volume: |
310 |
|
Pages: |
38-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yadav S |
Year: |
2023 |
Journal: |
Front Immunol |
Title: |
TLR4 activation by lysozyme induces pain without inflammation. |
Volume: |
14 |
|
Pages: |
1065226 |
|
•
•
•
•
•
|
Publication |
First Author: |
Agrawal V |
Year: |
2014 |
Journal: |
Biol Reprod |
Title: |
Platelet-activating factor: a role in preterm delivery and an essential interaction with Toll-like receptor signaling in mice. |
Volume: |
91 |
Issue: |
5 |
Pages: |
119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruwanpura SM |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice. |
Volume: |
8 |
Issue: |
10 |
Pages: |
e78095 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fan H |
Year: |
2016 |
Journal: |
Mol Neurodegener |
Title: |
Reactive astrocytes undergo M1 microglia/macrohpages-induced necroptosis in spinal cord injury. |
Volume: |
11 |
|
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zbesko JC |
Year: |
2021 |
Journal: |
Brain Behav Immun |
Title: |
IgA natural antibodies are produced following T-cell independent B-cell activation following stroke. |
Volume: |
91 |
|
Pages: |
578-586 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velupillai P |
Year: |
2012 |
Journal: |
J Virol |
Title: |
Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus. |
Volume: |
86 |
Issue: |
21 |
Pages: |
11541-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruiz J |
Year: |
2015 |
Journal: |
Front Cell Infect Microbiol |
Title: |
Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine. |
Volume: |
5 |
|
Pages: |
105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morgado P |
Year: |
2011 |
Journal: |
Infect Immun |
Title: |
Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. |
Volume: |
79 |
Issue: |
11 |
Pages: |
4401-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tabarean IV |
Year: |
2006 |
Journal: |
Neuroscience |
Title: |
Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons. |
Volume: |
141 |
Issue: |
4 |
Pages: |
1685-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zaidi TS |
Year: |
2010 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Role of neutrophils, MyD88-mediated neutrophil recruitment, and complement in antibody-mediated defense against Pseudomonas aeruginosa keratitis. |
Volume: |
51 |
Issue: |
4 |
Pages: |
2085-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muxel SM |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
Toll-Like Receptor and miRNA-let-7e Expression Alter the Inflammatory Response in Leishmania amazonensis-Infected Macrophages. |
Volume: |
9 |
|
Pages: |
2792 |
|
•
•
•
•
•
|
Publication |
First Author: |
Piao W |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain. |
Volume: |
110 |
Issue: |
47 |
Pages: |
19036-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Azuma M |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation. |
Volume: |
5 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
van der Geest R |
Year: |
2023 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonary Klebsiella pneumoniae infection. |
Volume: |
325 |
Issue: |
5 |
Pages: |
L604-L616 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith JA |
Year: |
2013 |
Journal: |
PLoS Pathog |
Title: |
Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages. |
Volume: |
9 |
Issue: |
12 |
Pages: |
e1003785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pfaender S |
Year: |
2016 |
Journal: |
PLoS Pathog |
Title: |
Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e1005736 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miraglia MC |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Glial Cell-Elicited Activation of Brain Microvasculature in Response to Brucella abortus Infection Requires ASC Inflammasome-Dependent IL-1β Production. |
Volume: |
196 |
Issue: |
9 |
Pages: |
3794-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh RK |
Year: |
2020 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates. |
Volume: |
40 |
Issue: |
1 |
Pages: |
86-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu YH |
Year: |
2018 |
Journal: |
Front Cell Infect Microbiol |
Title: |
The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation. |
Volume: |
8 |
|
Pages: |
84 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
589
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
358
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
380
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
309
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
100
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1961
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
199
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
401
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
387
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1758
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
534
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1985
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1181
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
309
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1807
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
413
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1940
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2622
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
411
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1943
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
401
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
401
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
573
|
Fragment?: |
false |
|
•
•
•
•
•
|