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Search results 101 to 200 out of 200 for Rxfp2

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0.064s
Type Details Score
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1927928
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2768126
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692468
Age: postnatal adult
Image: HMGU_692063
Specimen Label: HMGU_692063
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3001926
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:3001928
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2825426
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2825428
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2813626
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2813628
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:4402137
Assay Type: RNA in situ
Annotation Date: 2022-04-07
Strength: Strong
Sex: Male
Emaps: EMAPS:1908922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7260111
Age: embryonic day 14.5
Image: S4D
Note: Strong expression in gubernaculum.
Specimen Label: S4D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826026
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826028
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2814226
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2814228
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1897626
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1897628
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2969128
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_01
Specimen Label: euxassay_008331_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_02
Specimen Label: euxassay_008331_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_03
Specimen Label: euxassay_008331_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_04
Specimen Label: euxassay_008331_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_05
Specimen Label: euxassay_008331_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_06
Specimen Label: euxassay_008331_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_07
Specimen Label: euxassay_008331_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_08
Specimen Label: euxassay_008331_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_09
Specimen Label: euxassay_008331_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_10
Specimen Label: euxassay_008331_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_11
Specimen Label: euxassay_008331_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_14
Specimen Label: euxassay_008331_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_15
Specimen Label: euxassay_008331_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_16
Specimen Label: euxassay_008331_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_17
Specimen Label: euxassay_008331_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_18
Specimen Label: euxassay_008331_18
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_19
Specimen Label: euxassay_008331_19
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_20
Specimen Label: euxassay_008331_20
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_21
Specimen Label: euxassay_008331_21
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827841
Age: embryonic day 14.5
Image: euxassay_008331_22
Specimen Label: euxassay_008331_22
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826626
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826628
Stage: TS28
Assay Id: MGI:5540595
Age: postnatal day 84
Image: GUDMAP:15051
Specimen Label: GUDMAP:15051
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4422447
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772126
Stage: TS26
Assay Id: MGI:5540595
Age: embryonic day 17.5
Image: GUDMAP:15050
Specimen Label: GUDMAP:15050
Detected: false
Specimen Num: 1
Protein
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
Publication
First Author: Ceyhan Y
Year: 2020
Journal: PLoS One
Title: Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice.
Volume: 15
Issue: 5
Pages: e0233163
Publication
First Author: Bathgate RA
Year: 2006
Journal: Biochemistry
Title: Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.
Volume: 45
Issue: 3
Pages: 1043-53
Publication
First Author: Livermore C
Year: 2019
Journal: Sci Rep
Title: Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight.
Volume: 9
Issue: 1
Pages: 17195
Publication
First Author: Weiss J
Year: 2012
Journal: Mamm Genome
Title: ENU mutagenesis in mice identifies candidate genes for hypogonadism.
Volume: 23
Issue: 5-6
Pages: 346-55
Publication
First Author: Warr N
Year: 2009
Journal: Dev Biol
Title: Sfrp1 and Sfrp2 are required for normal male sexual development in mice.
Volume: 326
Issue: 2
Pages: 273-84
Publication
First Author: Kaftanovskaya EM
Year: 2015
Journal: FASEB J
Title: Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis.
Volume: 29
Issue: 6
Pages: 2327-37
Publication
First Author: Kaftanovskaya EM
Year: 2013
Journal: J Pathol
Title: Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis.
Volume: 230
Issue: 1
Pages: 39-47
Publication
First Author: Kothandapani A
Year: 2020
Journal: PLoS Genet
Title: GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.
Volume: 16
Issue: 6
Pages: e1008810
Publication
First Author: Basta JM
Year: 2014
Journal: Development
Title: Sall1 balances self-renewal and differentiation of renal progenitor cells.
Volume: 141
Issue: 5
Pages: 1047-58
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: cryptorchidism with white spotting, deletion region; cryptorchidism with white spotting
Allele Type: Transgenic
Attribute String: Null/knockout
Strain
Attribute String: transgenic, mutant strain, coisogenic
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Genotype
Symbol: crsp/crsp
Background: FVB/N-crsp
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: crsp/crsp
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Rxfp2/Rxfp2<+> crsp/?
Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
Protein Domain
Type: Family
Description: Insulin-like 3 (INSL3) is a secreted protein produced by testicular Leydig cells and in lower amounts by ovarian follicular theca interna cells and the corpus luteum []. It acts as a theca cell-derived growth factor for preantral follicle and its action is mediated by growth differentiation factor 9 []. Signaling through INSL3 and its cognate G protein-coupled receptor RXFP2 is important for testicular descent. It seems to be dispensable for spermatogenesis and fertility in adult males [].
Genotype
Symbol: Cav1/Cav1 crsp/crsp
Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cav1/Cav1 crsp/+
Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Brogiolo W
Year: 2001
Journal: Curr Biol
Title: An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.
Volume: 11
Issue: 4
Pages: 213-21
Protein Domain
Type: Family
Description: This entry includes insulin-like 3 from mammals and probable insulin-like peptide 4 (Ilp4 or dILP4) from fruit flies [].Insulin-like 3 (INSL3) is a secreted protein produced by testicular Leydig cells and in lower amounts by ovarian follicular theca interna cells and the corpus luteum []. It acts as a theca cell-derived growth factor for preantral follicle and its action is mediated by growth differentiation factor 9 []. Signaling through INSL3 and its cognate G protein-coupled receptor RXFP2 is important for testicular descent. It seems to be dispensable for spermatogenesis and fertility in adult males [].The function of Ilp4 is not clear.
Publication
First Author: Bathgate R
Year: 1996
Journal: Biol Reprod
Title: Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: sequence and messenger ribonucleic acid analysis.
Volume: 55
Issue: 6
Pages: 1452-7
Publication
First Author: Xue K
Year: 2014
Journal: Endocrinology
Title: Insulin-like 3-induced rat preantral follicular growth is mediated by growth differentiation factor 9.
Volume: 155
Issue: 1
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Title: Membrane receptors: structure and function of the relaxin family peptide receptors.
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Protein
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: false
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Title: Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway.
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