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Search results 1 to 100 out of 323 for Irf8

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Category: Publication
Type Details Score
Publication
First Author: Durai V
Year: 2019
Journal: Nat Immunol
Title: Cryptic activation of an Irf8 enhancer governs cDC1 fate specification.
Volume: 20
Issue: 9
Pages: 1161-1173
Publication
First Author: Bagadia P
Year: 2019
Journal: Nat Immunol
Title: An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development.
Volume: 20
Issue: 9
Pages: 1174-1185
Publication
First Author: Wang H
Year: 2008
Journal: Blood
Title: IRF8 regulates B-cell lineage specification, commitment, and differentiation.
Volume: 112
Issue: 10
Pages: 4028-38
Publication
First Author: Pathak S
Year: 2013
Journal: J Immunol
Title: A role for IRF8 in B cell anergy.
Volume: 191
Issue: 12
Pages: 6222-30
Publication
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
Publication
First Author: Li HS
Year: 2012
Journal: PLoS One
Title: miR-22 controls Irf8 mRNA abundance and murine dendritic cell development.
Volume: 7
Issue: 12
Pages: e52341
Publication  
First Author: Jiang DS
Year: 2014
Journal: Nat Commun
Title: IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling.
Volume: 5
Pages: 3303
Publication
First Author: Karki R
Year: 2020
Journal: J Immunol
Title: IRF8 Regulates Gram-Negative Bacteria-Mediated NLRP3 Inflammasome Activation and Cell Death.
Volume: 204
Issue: 9
Pages: 2514-2522
Publication
First Author: Adams NM
Year: 2018
Journal: Immunity
Title: Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response.
Volume: 48
Issue: 6
Pages: 1172-1182.e6
Publication
First Author: Pang SH
Year: 2016
Journal: Leukemia
Title: PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.
Volume: 30
Issue: 6
Pages: 1375-87
Publication  
First Author: Agod Z
Year: 2018
Journal: Front Immunol
Title: Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8.
Volume: 9
Pages: 62
Publication
First Author: Salem S
Year: 2014
Journal: Blood
Title: Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation.
Volume: 124
Issue: 12
Pages: 1894-904
Publication
First Author: Yang J
Year: 2011
Journal: J Immunol
Title: Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cells.
Volume: 187
Issue: 9
Pages: 4426-30
Publication  
First Author: Gupta M
Year: 2015
Journal: Nat Commun
Title: IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes.
Volume: 6
Pages: 6379
Publication
First Author: Tzetzo SL
Year: 2024
Journal: iScience
Title: Downregulation of IRF8 in alveolar macrophages by G-CSF promotes metastatic tumor progression.
Volume: 27
Issue: 3
Pages: 109187
Publication
First Author: Zhang Y
Year: 2020
Journal: Cell Rep
Title: SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes.
Volume: 30
Issue: 6
Pages: 1951-1963.e4
Publication
First Author: Mace EM
Year: 2017
Journal: J Clin Invest
Title: Biallelic mutations in IRF8 impair human NK cell maturation and function.
Volume: 127
Issue: 1
Pages: 306-320
Publication  
First Author: Ouyang X
Year: 2011
Journal: Nat Commun
Title: Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation.
Volume: 2
Pages: 314
Publication
First Author: Nixon BG
Year: 2022
Journal: Immunity
Title: Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.
Volume: 55
Issue: 11
Pages: 2044-2058.e5
Publication
First Author: Yoshida Y
Year: 2014
Journal: Immunity
Title: The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation.
Volume: 40
Issue: 2
Pages: 187-98
Publication
First Author: Luda KM
Year: 2016
Journal: Immunity
Title: IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis.
Volume: 44
Issue: 4
Pages: 860-74
Publication
First Author: Masuda T
Year: 2012
Journal: Cell Rep
Title: IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype.
Volume: 1
Issue: 4
Pages: 334-340
Publication
First Author: Murakami K
Year: 2021
Journal: Nat Immunol
Title: A RUNX-CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes.
Volume: 22
Issue: 3
Pages: 301-311
Publication
First Author: Tailor P
Year: 2008
Journal: Blood
Title: The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse.
Volume: 111
Issue: 4
Pages: 1942-5
Publication
First Author: Xu H
Year: 2012
Journal: Nat Immunol
Title: Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.
Volume: 13
Issue: 7
Pages: 642-50
Publication
First Author: Carotta S
Year: 2014
Journal: J Exp Med
Title: The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
Volume: 211
Issue: 11
Pages: 2169-81
Publication
First Author: Zhou N
Year: 2019
Journal: Protein Cell
Title: Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition.
Volume: 10
Issue: 2
Pages: 87-103
Publication  
First Author: Zhang R
Year: 2019
Journal: J Autoimmun
Title: T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation.
Volume: 96
Pages: 113-122
Publication
First Author: Hu X
Year: 2011
Journal: Cancer Res
Title: IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia.
Volume: 71
Issue: 8
Pages: 2882-91
Publication
First Author: Kurotaki D
Year: 2019
Journal: Blood
Title: Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice.
Volume: 133
Issue: 17
Pages: 1803-1813
Publication
First Author: Yáñez A
Year: 2015
Journal: Blood
Title: IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production.
Volume: 125
Issue: 9
Pages: 1452-9
Publication
First Author: Wang H
Year: 2014
Journal: J Immunol
Title: A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation.
Volume: 193
Issue: 4
Pages: 1766-77
Publication
First Author: Gaillard C
Year: 2018
Journal: Blood Adv
Title: Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia.
Volume: 2
Issue: 19
Pages: 2462-2466
Publication
First Author: Thumbigere-Math V
Year: 2019
Journal: J Bone Miner Res
Title: Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption.
Volume: 34
Issue: 6
Pages: 1155-1168
Publication    
First Author: Xu H
Year: 2023
Journal: Elife
Title: A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation.
Volume: 12
Publication
First Author: Schönheit J
Year: 2013
Journal: Cell Rep
Title: PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Volume: 3
Issue: 5
Pages: 1617-28
Publication
First Author: Kim S
Year: 2020
Journal: Immunity
Title: High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity.
Volume: 53
Issue: 4
Pages: 759-774.e9
Publication
First Author: Scheller M
Year: 2013
Journal: J Exp Med
Title: Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.
Volume: 210
Issue: 11
Pages: 2239-56
Publication
First Author: Ototake Y
Year: 2021
Journal: J Invest Dermatol
Title: Downregulated IRF8 in Monocytes and Macrophages of Patients with Systemic Sclerosis May Aggravate the Fibrotic Phenotype.
Volume: 141
Issue: 8
Pages: 1954-1963
Publication
First Author: Ibrahim ML
Year: 2018
Journal: Cell Rep
Title: Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis.
Volume: 25
Issue: 11
Pages: 3036-3046.e6
Publication
First Author: Sichien D
Year: 2016
Journal: Immunity
Title: IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively.
Volume: 45
Issue: 3
Pages: 626-640
Publication
First Author: Grajales-Reyes GE
Year: 2015
Journal: Nat Immunol
Title: Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Volume: 16
Issue: 7
Pages: 708-17
Publication
First Author: Yamamoto M
Year: 2011
Journal: PLoS One
Title: Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development.
Volume: 6
Issue: 10
Pages: e25812
Publication
First Author: Bajaña S
Year: 2016
Journal: J Immunol
Title: IRF4 and IRF8 Act in CD11c+ Cells To Regulate Terminal Differentiation of Lung Tissue Dendritic Cells.
Volume: 196
Issue: 4
Pages: 1666-77
Publication
First Author: Yan M
Year: 2016
Journal: J Immunol
Title: Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.
Volume: 196
Issue: 5
Pages: 1999-2003
Publication
First Author: Hagemeyer N
Year: 2016
Journal: EMBO J
Title: Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation.
Volume: 35
Issue: 16
Pages: 1730-44
Publication
First Author: Baccala R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus.
Volume: 110
Issue: 8
Pages: 2940-5
Publication
First Author: Sasaki H
Year: 2015
Journal: Blood
Title: Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells.
Volume: 125
Issue: 2
Pages: 358-69
Publication
First Author: Kurotaki D
Year: 2018
Journal: Cell Rep
Title: Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors.
Volume: 22
Issue: 10
Pages: 2628-2641
Publication
First Author: Shin DM
Year: 2011
Journal: PLoS One
Title: IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells.
Volume: 6
Issue: 11
Pages: e27384
Publication
First Author: Wang H
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses.
Volume: 116
Issue: 19
Pages: 9511-9520
Publication
First Author: Fortier A
Year: 2009
Journal: Infect Immun
Title: Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.
Volume: 77
Issue: 11
Pages: 4794-805
Publication
First Author: Pearl D
Year: 2020
Journal: J Immunol
Title: 4E-BP-Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response.
Volume: 204
Issue: 9
Pages: 2392-2400
Publication  
First Author: Das A
Year: 2021
Journal: Front Immunol
Title: Mutation in Irf8 Gene (Irf8R294C ) Impairs Type I IFN-Mediated Antiviral Immune Response by Murine pDCs.
Volume: 12
Pages: 758190
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for gemini2.
Publication  
First Author: Anderson DA
Year: 2022
Journal: J Exp Med
Title: Transition from cMyc to L-Myc during dendritic cell development coordinated by rising levels of IRF8.
Volume: 219
Issue: 2
Publication
First Author: Liu TT
Year: 2022
Journal: Nature
Title: Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.
Volume: 607
Issue: 7917
Pages: 142-148
Publication
First Author: Miyagawa F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cells.
Volume: 109
Issue: 30
Pages: 12123-8
Publication
First Author: Kobayakawa K
Year: 2019
Journal: Sci Adv
Title: Macrophage centripetal migration drives spontaneous healing process after spinal cord injury.
Volume: 5
Issue: 5
Pages: eaav5086
Publication
First Author: Cheng J
Year: 2017
Journal: Inflammation
Title: miRNA-451a Targets IFN Regulatory Factor 8 for the Progression of Systemic Lupus Erythematosus.
Volume: 40
Issue: 2
Pages: 676-687
Publication
First Author: Humblin E
Year: 2017
Journal: Nat Commun
Title: IRF8-dependent molecular complexes control the Th9 transcriptional program.
Volume: 8
Issue: 1
Pages: 2085
Publication
First Author: de Mingo Pulido Á
Year: 2018
Journal: Cancer Cell
Title: TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer.
Volume: 33
Issue: 1
Pages: 60-74.e6
Publication
First Author: Masuda T
Year: 2015
Journal: J Pharmacol Sci
Title: Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia.
Volume: 128
Issue: 4
Pages: 216-20
Publication
First Author: Minten C
Year: 2012
Journal: PLoS One
Title: IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS.
Volume: 7
Issue: 11
Pages: e49851
Publication
First Author: Netherby CS
Year: 2017
Journal: J Immunol
Title: The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production.
Volume: 198
Issue: 10
Pages: 4129-4139
Publication
First Author: Zhao B
Year: 2009
Journal: Nat Med
Title: Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis.
Volume: 15
Issue: 9
Pages: 1066-71
Publication
First Author: Xiang M
Year: 2014
Journal: J Neurochem
Title: Interferon regulatory factor 8 protects against cerebral ischaemic-reperfusion injury.
Volume: 129
Issue: 6
Pages: 988-1001
Publication
First Author: Kurotaki D
Year: 2013
Journal: Blood
Title: Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation.
Volume: 121
Issue: 10
Pages: 1839-49
Publication
First Author: Zhou JX
Year: 2009
Journal: J Immunol
Title: IFN regulatory factor 8 regulates MDM2 in germinal center B cells.
Volume: 183
Issue: 5
Pages: 3188-94
Publication  
First Author: Qiu Z
Year: 2020
Journal: Cancer Genet
Title: Generation and characterization of the Eµ-Irf8 mouse model.
Volume: 245
Pages: 6-16
Publication  
First Author: Li N
Year: 2021
Journal: Front Immunol
Title: IRF8-Dependent Type I Conventional Dendritic Cells (cDC1s) Control Post-Ischemic Inflammation and Mildly Protect Against Post-Ischemic Acute Kidney Injury and Disease.
Volume: 12
Pages: 685559
Publication  
First Author: Saburi M
Year: 2021
Journal: Cells
Title: Maternal High-Fat Diet Promotes Abdominal Aortic Aneurysm Expansion in Adult Offspring by Epigenetic Regulation of IRF8-Mediated Osteoclast-like Macrophage Differentiation.
Volume: 10
Issue: 9
Publication
First Author: Tailor P
Year: 2007
Journal: Immunity
Title: The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8.
Volume: 27
Issue: 2
Pages: 228-39
Publication  
First Author: Zhang S
Year: 2021
Journal: Sci Immunol
Title: Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT.
Volume: 6
Issue: 58
Publication
First Author: Bagadia P
Year: 2021
Journal: J Immunol
Title: Bcl6-Independent In Vivo Development of Functional Type 1 Classical Dendritic Cells Supporting Tumor Rejection.
Volume: 207
Issue: 1
Pages: 125-132
Publication
First Author: Valanparambil RM
Year: 2017
Journal: PLoS Pathog
Title: IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection.
Volume: 13
Issue: 10
Pages: e1006647
Publication
First Author: Cohen SB
Year: 2015
Journal: J Immunol
Title: Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells.
Volume: 194
Issue: 1
Pages: 210-22
Publication
First Author: Xu H
Year: 2015
Journal: Nat Immunol
Title: Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.
Volume: 16
Issue: 12
Pages: 1274-81
Publication
First Author: Van Hove H
Year: 2019
Journal: Nat Neurosci
Title: A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.
Volume: 22
Issue: 6
Pages: 1021-1035
Publication
First Author: Cougnoux A
Year: 2018
Journal: Hum Mol Genet
Title: Microglia activation in Niemann-Pick disease, type C1 is amendable to therapeutic intervention.
Volume: 27
Issue: 12
Pages: 2076-2089
Publication
First Author: Feng J
Year: 2011
Journal: J Immunol
Title: IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools.
Volume: 186
Issue: 3
Pages: 1458-66
Publication
First Author: Hu L
Year: 2013
Journal: J Clin Invest
Title: Increased Fanconi C expression contributes to the emergency granulopoiesis response.
Volume: 123
Issue: 9
Pages: 3952-66
Publication
First Author: Lee CH
Year: 2006
Journal: J Exp Med
Title: Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein.
Volume: 203
Issue: 1
Pages: 63-72
Publication
First Author: Schwieger M
Year: 2009
Journal: Blood
Title: Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C.
Volume: 114
Issue: 12
Pages: 2476-88
Publication
First Author: Kinder M
Year: 2010
Journal: Exp Hematol
Title: Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.
Volume: 38
Issue: 11
Pages: 1036-1046.e1-4
Publication  
First Author: Gardner AI
Year: 2021
Journal: J Biol Chem
Title: Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis.
Volume: 296
Pages: 100650
Publication
First Author: Zhang P
Year: 2021
Journal: J Neuroinflammation
Title: The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation.
Volume: 18
Issue: 1
Pages: 215
Publication
First Author: Yang D
Year: 2007
Journal: J Immunol
Title: IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression.
Volume: 179
Issue: 7
Pages: 4775-82
Publication
First Author: Paschall AV
Year: 2015
Journal: J Immunol
Title: IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.
Volume: 194
Issue: 5
Pages: 2369-79
Publication
First Author: Tussiwand R
Year: 2012
Journal: Nature
Title: Compensatory dendritic cell development mediated by BATF-IRF interactions.
Volume: 490
Issue: 7421
Pages: 502-7
Publication  
First Author: Morita M
Year: 2016
Journal: Sci Rep
Title: Smad4 is required to inhibit osteoclastogenesis and maintain bone mass.
Volume: 6
Pages: 35221
Publication
First Author: Hérault A
Year: 2017
Journal: Nature
Title: Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Volume: 544
Issue: 7648
Pages: 53-58
Publication
First Author: Seillet C
Year: 2013
Journal: Blood
Title: CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3.
Volume: 121
Issue: 9
Pages: 1574-83
Publication
First Author: Bosteels C
Year: 2020
Journal: Immunity
Title: Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Volume: 52
Issue: 6
Pages: 1039-1056.e9
Publication
First Author: Ma S
Year: 2006
Journal: J Immunol
Title: IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development.
Volume: 177
Issue: 11
Pages: 7898-904
Publication
First Author: Sun L
Year: 2016
Journal: PLoS One
Title: Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.
Volume: 11
Issue: 5
Pages: e0155420
Publication
First Author: Zhang SM
Year: 2014
Journal: Mol Cell Biol
Title: Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin.
Volume: 34
Issue: 3
Pages: 400-14
Publication
First Author: Chang TH
Year: 2012
Journal: J Immunol
Title: The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation.
Volume: 189
Issue: 7
Pages: 3548-56
Publication
First Author: Redd PS
Year: 2017
Journal: Cancer Res
Title: SETD1B Activates iNOS Expression in Myeloid-Derived Suppressor Cells.
Volume: 77
Issue: 11
Pages: 2834-2843
Publication
First Author: Jaiswal H
Year: 2013
Journal: J Immunol
Title: Batf3 and Id2 have a synergistic effect on Irf8-directed classical CD8α+ dendritic cell development.
Volume: 191
Issue: 12
Pages: 5993-6001