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Search results 101 to 200 out of 624 for Irf8

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Type Details Score
Publication
First Author: Cougnoux A
Year: 2018
Journal: Hum Mol Genet
Title: Microglia activation in Niemann-Pick disease, type C1 is amendable to therapeutic intervention.
Volume: 27
Issue: 12
Pages: 2076-2089
Publication
First Author: Kinder M
Year: 2010
Journal: Exp Hematol
Title: Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.
Volume: 38
Issue: 11
Pages: 1036-1046.e1-4
Publication
First Author: Feng J
Year: 2011
Journal: J Immunol
Title: IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools.
Volume: 186
Issue: 3
Pages: 1458-66
Publication
First Author: Yang D
Year: 2007
Journal: J Immunol
Title: IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression.
Volume: 179
Issue: 7
Pages: 4775-82
Publication
First Author: Paschall AV
Year: 2015
Journal: J Immunol
Title: IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.
Volume: 194
Issue: 5
Pages: 2369-79
Publication
First Author: Hu L
Year: 2013
Journal: J Clin Invest
Title: Increased Fanconi C expression contributes to the emergency granulopoiesis response.
Volume: 123
Issue: 9
Pages: 3952-66
Publication
First Author: Lee CH
Year: 2006
Journal: J Exp Med
Title: Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein.
Volume: 203
Issue: 1
Pages: 63-72
Publication
First Author: Schwieger M
Year: 2009
Journal: Blood
Title: Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C.
Volume: 114
Issue: 12
Pages: 2476-88
Publication  
First Author: Gardner AI
Year: 2021
Journal: J Biol Chem
Title: Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis.
Volume: 296
Pages: 100650
Publication
First Author: Zhang P
Year: 2021
Journal: J Neuroinflammation
Title: The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation.
Volume: 18
Issue: 1
Pages: 215
Publication
First Author: Tussiwand R
Year: 2012
Journal: Nature
Title: Compensatory dendritic cell development mediated by BATF-IRF interactions.
Volume: 490
Issue: 7421
Pages: 502-7
Publication  
First Author: Morita M
Year: 2016
Journal: Sci Rep
Title: Smad4 is required to inhibit osteoclastogenesis and maintain bone mass.
Volume: 6
Pages: 35221
Publication
First Author: Hérault A
Year: 2017
Journal: Nature
Title: Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Volume: 544
Issue: 7648
Pages: 53-58
Publication
First Author: Seillet C
Year: 2013
Journal: Blood
Title: CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3.
Volume: 121
Issue: 9
Pages: 1574-83
Publication
First Author: Bosteels C
Year: 2020
Journal: Immunity
Title: Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Volume: 52
Issue: 6
Pages: 1039-1056.e9
Publication
First Author: Ma S
Year: 2006
Journal: J Immunol
Title: IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development.
Volume: 177
Issue: 11
Pages: 7898-904
Publication
First Author: Sun L
Year: 2016
Journal: PLoS One
Title: Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.
Volume: 11
Issue: 5
Pages: e0155420
Publication
First Author: Zhang SM
Year: 2014
Journal: Mol Cell Biol
Title: Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin.
Volume: 34
Issue: 3
Pages: 400-14
Publication
First Author: Chang TH
Year: 2012
Journal: J Immunol
Title: The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation.
Volume: 189
Issue: 7
Pages: 3548-56
Publication
First Author: Redd PS
Year: 2017
Journal: Cancer Res
Title: SETD1B Activates iNOS Expression in Myeloid-Derived Suppressor Cells.
Volume: 77
Issue: 11
Pages: 2834-2843
Publication
First Author: Jaiswal H
Year: 2013
Journal: J Immunol
Title: Batf3 and Id2 have a synergistic effect on Irf8-directed classical CD8α+ dendritic cell development.
Volume: 191
Issue: 12
Pages: 5993-6001
Publication
First Author: Ayithan N
Year: 2015
Journal: PLoS One
Title: Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection.
Volume: 10
Issue: 2
Pages: e0118345
Publication  
First Author: Kim S
Year: 2023
Journal: J Exp Med
Title: IL-6 selectively suppresses cDC1 specification via C/EBPβ.
Volume: 220
Issue: 10
Publication
First Author: Yoon J
Year: 2014
Journal: J Biol Chem
Title: Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR.
Volume: 289
Issue: 49
Pages: 34250-7
Publication
First Author: Sjöstrand M
Year: 2013
Journal: J Immunol
Title: Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.
Volume: 191
Issue: 7
Pages: 3753-63
Publication
First Author: Audiger C
Year: 2020
Journal: J Immunol
Title: Merocytic Dendritic Cells Compose a Conventional Dendritic Cell Subset with Low Metabolic Activity.
Volume: 205
Issue: 1
Pages: 121-132
Publication
First Author: Jeong E
Year: 2020
Journal: FASEB J
Title: Early estrogen-induced gene 1 facilitates osteoclast formation through the inhibition of interferon regulatory factor 8 expression.
Volume: 34
Issue: 9
Pages: 12894-12906
Publication
First Author: Klement JD
Year: 2018
Journal: J Clin Invest
Title: An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion.
Volume: 128
Issue: 12
Pages: 5549-5560
Publication
First Author: Laricchia-Robbio L
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages.
Volume: 102
Issue: 40
Pages: 14368-73
Publication
First Author: Mittal D
Year: 2017
Journal: Cancer Immunol Res
Title: Interleukin-12 from CD103+ Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis.
Volume: 5
Issue: 12
Pages: 1098-1108
Publication
First Author: Pourcet B
Year: 2011
Journal: Circ Res
Title: LXRα regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8.
Volume: 109
Issue: 5
Pages: 492-501
Publication
First Author: Berghout J
Year: 2013
Journal: PLoS Pathog
Title: Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.
Volume: 9
Issue: 7
Pages: e1003491
Publication
First Author: Russler-Germain EV
Year: 2021
Journal: Immunity
Title: Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and limits other infections.
Volume: 54
Issue: 11
Pages: 2547-2564.e7
Publication
First Author: Lauterbach H
Year: 2010
Journal: J Exp Med
Title: Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.
Volume: 207
Issue: 12
Pages: 2703-17
Publication
First Author: Langlais D
Year: 2016
Journal: J Exp Med
Title: The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.
Volume: 213
Issue: 4
Pages: 585-603
Allele
Name: interferon regulatory factor 8; endonuclease-mediated mutation 1, Kenneth Murphy
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Allele
Name: interferon regulatory factor 8; endonuclease-mediated mutation 2, Kenneth Murphy
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Publication
First Author: Ferris ST
Year: 2020
Journal: Nature
Title: cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity.
Volume: 584
Issue: 7822
Pages: 624-629
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Schiavoni G
Year: 2002
Journal: J Exp Med
Title: ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.
Volume: 196
Issue: 11
Pages: 1415-25
Publication
First Author: Aliberti J
Year: 2003
Journal: Blood
Title: Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells.
Volume: 101
Issue: 1
Pages: 305-10
Publication
First Author: Tsujimura H
Year: 2003
Journal: J Immunol
Title: Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells.
Volume: 170
Issue: 3
Pages: 1131-5
Publication
First Author: Lorenzi S
Year: 2011
Journal: J Immunol
Title: Type I IFNs control antigen retention and survival of CD8α(+) dendritic cells after uptake of tumor apoptotic cells leading to cross-priming.
Volume: 186
Issue: 9
Pages: 5142-50
Publication
First Author: Turcotte K
Year: 2004
Journal: Blood
Title: Genetic control of myeloproliferation in BXH-2 mice.
Volume: 103
Issue: 6
Pages: 2343-50
Publication
First Author: Marquis JF
Year: 2009
Journal: J Immunol
Title: Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8.
Volume: 182
Issue: 5
Pages: 3008-15
Publication
First Author: Turcotte K
Year: 2007
Journal: J Immunol
Title: Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens.
Volume: 179
Issue: 4
Pages: 2467-76
Publication
First Author: Leylek R
Year: 2019
Journal: Cell Rep
Title: Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population.
Volume: 29
Issue: 11
Pages: 3736-3750.e8
Publication
First Author: Holtschke T
Year: 1996
Journal: Cell
Title: Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene.
Volume: 87
Issue: 2
Pages: 307-17
Publication
First Author: Hu L
Year: 2016
Journal: J Biol Chem
Title: The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis.
Volume: 291
Issue: 8
Pages: 4107-20
Publication
First Author: Scheller M
Year: 1999
Journal: Blood
Title: Altered development and cytokine responses of myeloid progenitors in the absence of transcription factor, interferon consensus sequence binding protein.
Volume: 94
Issue: 11
Pages: 3764-71
Publication
First Author: Morawetz RA
Year: 1998
Journal: Braz J Med Biol Res
Title: Relationship of cytokines and cytokine signaling to immunodeficiency disorders in the mouse.
Volume: 31
Issue: 1
Pages: 61-7
Publication
First Author: Tsujimura H
Year: 2004
Journal: J Immunol
Title: Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells.
Volume: 172
Issue: 11
Pages: 6820-7
Publication
First Author: Wu CY
Year: 1999
Journal: J Immunol
Title: Differential requirement of IFN consensus sequence binding protein for the production of IL-12 and induction of Th1-type cells in response to IFN-gamma.
Volume: 162
Issue: 2
Pages: 807-12
Publication
First Author: Hein J
Year: 2000
Journal: Infect Immun
Title: Interferon consensus sequence binding protein confers resistance against Yersinia enterocolitica.
Volume: 68
Issue: 3
Pages: 1408-17
Publication
First Author: Giese NA
Year: 1997
Journal: J Exp Med
Title: Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression.
Volume: 186
Issue: 9
Pages: 1535-46
Publication
First Author: Contursi C
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNgamma-responsive promoters in macrophages.
Volume: 97
Issue: 1
Pages: 91-6
Publication
First Author: Becker AM
Year: 2012
Journal: Blood
Title: IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors.
Volume: 119
Issue: 9
Pages: 2003-12
Publication
First Author: Milanovic M
Year: 2008
Journal: J Immunol
Title: IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development.
Volume: 181
Issue: 7
Pages: 5045-53
Publication
First Author: Gurevich RM
Year: 2006
Journal: Exp Hematol
Title: Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.
Volume: 34
Issue: 9
Pages: 1192-201
Publication
First Author: Schiavoni G
Year: 2004
Journal: Blood
Title: ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells.
Volume: 103
Issue: 6
Pages: 2221-8
Publication
First Author: Rocca S
Year: 2013
Journal: PLoS One
Title: Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis.
Volume: 8
Issue: 5
Pages: e62751
Publication  
First Author: Horiuchi M
Year: 2012
Journal: J Neuroinflammation
Title: Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia.
Volume: 9
Pages: 227
Publication
First Author: Döring Y
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Hematopoietic interferon regulatory factor 8-deficiency accelerates atherosclerosis in mice.
Volume: 32
Issue: 7
Pages: 1613-23
Publication
First Author: Tamura T
Year: 2002
Journal: J Interferon Cytokine Res
Title: ICSBP/IRF-8: its regulatory roles in the development of myeloid cells.
Volume: 22
Issue: 1
Pages: 145-52
Publication
First Author: Gabriele L
Year: 1999
Journal: J Exp Med
Title: Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein.
Volume: 190
Issue: 3
Pages: 411-21
Publication
First Author: Mattei F
Year: 2012
Journal: Neoplasia
Title: IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment.
Volume: 14
Issue: 12
Pages: 1223-35
Publication
First Author: Tamura T
Year: 2000
Journal: Immunity
Title: ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.
Volume: 13
Issue: 2
Pages: 155-65
Publication
First Author: Huang W
Year: 2006
Journal: Mol Cell Biol
Title: Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein.
Volume: 26
Issue: 17
Pages: 6311-32
Publication
First Author: Huang W
Year: 2010
Journal: Mol Cell Biol
Title: Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription.
Volume: 30
Issue: 19
Pages: 4575-94
GXD Expression    
Probe: MGI:6865638
Assay Type: RT-PCR
Annotation Date: 1999-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:1339229
Age: postnatal week 6
Image: 2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1339157
Assay Type: Western blot
Annotation Date: 1999-07-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:1339249
Age: postnatal week 6
Image: 2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1339157
Assay Type: Western blot
Annotation Date: 1999-07-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:1339261
Age: postnatal week 6
Image: 2
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816622
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816622
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816622
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816622
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816622
Age: embryonic day 3.0
Specimen Label: Morula
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816622
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816622
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:3815818
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816622
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:5288022
Assay Type: RT-PCR
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5291933
Age: postnatal
Image: 4
Specimen Label: Control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6865638
Assay Type: RT-PCR
Annotation Date: 2022-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:6865639
Age: postnatal week 6
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1