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Search results 501 to 600 out of 624 for Irf8

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Type Details Score
Publication
First Author: Mandal M
Year: 2009
Journal: Nat Immunol
Title: Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development.
Volume: 10
Issue: 10
Pages: 1110-7
Publication
First Author: Blasius AL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.
Volume: 107
Issue: 46
Pages: 19973-8
Publication
First Author: Chudnovskiy A
Year: 2016
Journal: Cell
Title: Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Volume: 167
Issue: 2
Pages: 444-456.e14
Publication
First Author: Sollars VE
Year: 2006
Journal: Mamm Genome
Title: Analysis of expansion of myeloid progenitors in mice to identify leukemic susceptibility genes.
Volume: 17
Issue: 8
Pages: 808-21
Publication
First Author: Kozak CA
Year: 1995
Journal: Genomics
Title: Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.
Volume: 27
Issue: 3
Pages: 405-11
Publication
First Author: Zhang H
Year: 2020
Journal: Cell Rep
Title: An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.
Volume: 33
Issue: 8
Pages: 108433
Publication
First Author: Masuda T
Year: 2022
Journal: Nature
Title: Specification of CNS macrophage subsets occurs postnatally in defined niches.
Volume: 604
Issue: 7907
Pages: 740-748
Publication
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
Publication
First Author: Bettigole SE
Year: 2015
Journal: Nat Immunol
Title: The transcription factor XBP1 is selectively required for eosinophil differentiation.
Volume: 16
Issue: 8
Pages: 829-37
Publication
First Author: Lyu MS
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the human and mouse phospholipase C genes.
Volume: 7
Issue: 7
Pages: 501-4
Publication
First Author: Lyu MS
Year: 1999
Journal: Mamm Genome
Title: Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences.
Volume: 10
Issue: 10
Pages: 1017-9
Publication    
First Author: Catela C
Year: 2022
Journal: Elife
Title: Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.
Volume: 11
Publication
First Author: Kozak CA
Year: 1999
Journal: Mamm Genome
Title: Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus.
Volume: 10
Issue: 9
Pages: 853-7
Publication
First Author: Sundberg JP
Year: 2017
Journal: PLoS One
Title: Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Volume: 12
Issue: 7
Pages: e0180682
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
Publication
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Allele
Name: interferon regulatory factor 8; endonuclease-mediated mutation 3, Kenneth Murphy
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Publication  
First Author: Chauhan KS
Year: 2022
Journal: Cell Immunol
Title: IRF8 and BATF3 interaction enhances the cDC1 specific Pfkfb3 gene expression.
Volume: 371
Pages: 104468
DO Term
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Publication
First Author: Patel A
Year: 2021
Journal: J Immunol
Title: Multimodal Intralesional Therapy for Reshaping the Myeloid Compartment of Tumors Resistant to Anti-PD-L1 Therapy via IRF8 Expression.
Volume: 207
Issue: 5
Pages: 1298-1309
DO Term
GXD Expression  
Probe: MGI:7380580
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382870
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:5620494
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382874
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7380580
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382870
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:5620494
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382874
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7380580
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382870
Age: embryonic day 14.5
Note: There was a reduction in the number of meningeal macrophages noted in the Irf8 mutant background.
Specimen Label: 3f Meninges Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:5620494
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382874
Age: embryonic day 14.5
Note: There was a reduction in the number of meningeal macrophages noted in the Irf8 mutant background.
Specimen Label: 3f Meninges Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 3
Allele
Name: interferon regulatory factor 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
MP Term
MP Term
MP Term
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: interferon regulatory factor 8; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
Strain
Attribute String: mutant strain, coisogenic, chemically induced mutation
Genotype
Symbol: Irf8/Irf8
Background: C57BL/6J-Irf8
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, coisogenic
Genotype
Symbol: Irf8/Irf8 Rr253/Rr253
Background: C57BL/6J-Irf8 Rr253
Zygosity: cx
Has Mutant Allele: true
HT Experiment
Series Id: GSE5800
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Allele
Name: PCNA clamp associated factor; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Publication
First Author: Glasmacher E
Year: 2012
Journal: Science
Title: A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.
Volume: 338
Issue: 6109
Pages: 975-80
Publication
First Author: Ledo JH
Year: 2020
Journal: PLoS One
Title: Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development.
Volume: 15
Issue: 8
Pages: e0237773
Publication
First Author: Tussiwand R
Year: 2015
Journal: Immunity
Title: Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses.
Volume: 42
Issue: 5
Pages: 916-28
Publication
First Author: Vander Lugt B
Year: 2014
Journal: Nat Immunol
Title: Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.
Volume: 15
Issue: 2
Pages: 161-7
Publication
First Author: Jaitin DA
Year: 2016
Journal: Cell
Title: Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.
Volume: 167
Issue: 7
Pages: 1883-1896.e15
Publication
First Author: Esashi E
Year: 2008
Journal: Immunity
Title: The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8.
Volume: 28
Issue: 4
Pages: 509-20
Publication
First Author: Ingraham CR
Year: 2006
Journal: Nat Genet
Title: Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6).
Volume: 38
Issue: 11
Pages: 1335-40
Publication
First Author: de Bruin AM
Year: 2012
Journal: Blood
Title: IFNγ induces monopoiesis and inhibits neutrophil development during inflammation.
Volume: 119
Issue: 6
Pages: 1543-54
Publication
First Author: Bornstein C
Year: 2014
Journal: Mol Cell
Title: A negative feedback loop of transcription factors specifies alternative dendritic cell chromatin States.
Volume: 56
Issue: 6
Pages: 749-62
Publication
First Author: López-Yglesias AH
Year: 2021
Journal: PLoS Pathog
Title: T-bet-dependent ILC1- and NK cell-derived IFN-γ mediates cDC1-dependent host resistance against Toxoplasma gondii.
Volume: 17
Issue: 1
Pages: e1008299
Genotype
Symbol: Pclaf/Pclaf
Background: C57BL/6N-Pclaf/Wtsi
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Nishikawa K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Blimp1-mediated repression of negative regulators is required for osteoclast differentiation.
Volume: 107
Issue: 7
Pages: 3117-22
Publication  
First Author: Swarnkar G
Year: 2016
Journal: Sci Rep
Title: Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors.
Volume: 6
Pages: 29896
Publication
First Author: Petkau G
Year: 2022
Journal: Nat Commun
Title: The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins.
Volume: 13
Issue: 1
Pages: 2274
Publication
First Author: Satpathy AT
Year: 2014
Journal: Blood
Title: Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.
Volume: 123
Issue: 19
Pages: 2968-77
Publication
First Author: Duggan JM
Year: 2017
Journal: Blood
Title: BCAP inhibits proliferation and differentiation of myeloid progenitors in the steady state and during demand situations.
Volume: 129
Issue: 11
Pages: 1503-1513