|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 701 to 800 out of 929 for Alk

0.074s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
UniProt Feature
Begin: 26
Description: ALK and LTK ligand 2
Type: chain
End: 151
UniProt Feature
Begin: 28
Description: ALK and LTK ligand 1
Type: chain
End: 127
Publication
First Author: Lu L
Year: 2009
Journal: Biochemistry
Title: ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors.
Volume: 48
Issue: 16
Pages: 3600-9
Publication
First Author: Gerber DE
Year: 2010
Journal: Cancer Cell
Title: ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time.
Volume: 18
Issue: 6
Pages: 548-51
Publication
First Author: Kuo AH
Year: 2007
Journal: Oncogene
Title: Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase.
Volume: 26
Issue: 6
Pages: 859-69
Publication
First Author: Palmer RH
Year: 2009
Journal: Biochem J
Title: Anaplastic lymphoma kinase: signalling in development and disease.
Volume: 420
Issue: 3
Pages: 345-61
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: true
Publication
First Author: Yun MR
Year: 2018
Journal: Cancer Res
Title: Enhancer Remodeling and MicroRNA Alterations Are Associated with Acquired Resistance to ALK Inhibitors.
Volume: 78
Issue: 12
Pages: 3350-3362
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Ahmed M
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: A hypothalamic pathway for Augmentor α-controlled body weight regulation.
Volume: 119
Issue: 16
Pages: e2200476119
Publication
First Author: Illert AL
Year: 2012
Journal: Development
Title: Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase.
Volume: 139
Issue: 14
Pages: 2523-34
Pathway
Allele  
Name: ALK and LTK ligand 2; wild type
Allele Type: Not Specified
Allele  
Name: ALK and LTK ligand 1; wild type
Allele Type: Not Specified
Interaction Experiment
Description: ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.
Publication  
First Author: Saville JT
Year: 2016
Journal: Exp Neurol
Title: Selective normalisation of regional brain bis(monoacylglycero)phosphate in the mucopolysaccharidosis 1 (Hurler) mouse.
Volume: 277
Pages: 68-75
Publication
First Author: Nouri K
Year: 2019
Journal: FASEB J
Title: A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Volume: 33
Issue: 11
Pages: 12487-12499
Allele
Name: ALK and LTK ligand 2; targeted mutation 1, Joseph Schlessinger
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: ALK and LTK ligand 2; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: ALK and LTK ligand 1; targeted mutation 1, Lexicon Pharmaceuticals
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: ALK and LTK ligand 1; gene trap RRK010, BayGenomics
Allele Type: Gene trapped
Allele
Name: ALK and LTK ligand 1; targeted mutation 1, Joseph Schlessinger
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7544035
Age: embryonic day 15.5
Image: EV1
Specimen Label: E15.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7544035
Age: postnatal day 0
Image: EV1
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7544035
Age: postnatal day 2
Image: EV1
Specimen Label: P2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7544035
Age: postnatal day 7
Image: EV1
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7544035
Age: postnatal adult
Image: EV1
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7544037
Age: embryonic day 15.5
Image: EV1
Specimen Label: E15.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7544037
Age: postnatal day 0
Image: EV1
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7544037
Age: postnatal day 2
Image: EV1
Specimen Label: P2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544037
Age: postnatal day 7
Image: EV1
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544037
Age: postnatal adult
Image: EV1
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7544916
Age: embryonic day 15.5
Image: EV3
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal day 20
Image: EV3
Specimen Label: P20 WT
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal month 3-6
Image: EV3
Specimen Label: Adult WT
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7544916
Age: embryonic day 15.5
Image: EV3
Specimen Label: E15.5 DKO
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal day 20
Image: EV3
Specimen Label: P20 DKO
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal month 3-6
Image: EV3
Specimen Label: Adult DKO
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1B
Specimen Label: EV1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1A
Specimen Label: EV1A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1D
Specimen Label: EV1D
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Specimen Label: EV1E
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the ventrolateral thalamic nucleus.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the hypothalamic area.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1A
Specimen Label: EV1A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the amygdaloid area.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1A
Specimen Label: EV1A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1D
Specimen Label: EV1D
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the lateral olfactory bulb.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1F
Specimen Label: EV1F
Detected: true
Specimen Num: 5
Pathway
Pathway
Publication
First Author: Tang SC
Year: 2014
Journal: Int J Cancer
Title: Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.
Volume: 134
Issue: 6
Pages: 1484-94
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: ALK and LTK ligand 2; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: ALK and LTK ligand 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: mutant stock, targeted mutation