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Search results 101 to 153 out of 153 for Cabyr

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: testis
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: thymus
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: skin
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: uterus
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: brain
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: ovary
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Stage: TS28
Assay Id: MGI:5649234
Age: postnatal adult
Image: 5
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1929228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 8/A
Specimen Label: 8/A
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1929328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Note: Expression is present in sperm located in the lumen of the epididymal duct.
Specimen Label: not shown
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Male
Emaps: EMAPS:3044528
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 8/A
Specimen Label: 8/A
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Male
Emaps: EMAPS:3148628
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7A
Note: No expression in round or elongating spermatids.
Specimen Label: 7A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7B
Note: Expression present in elongating spermatids.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7C
Specimen Label: 7C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7D
Specimen Label: 7D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7E
Specimen Label: 7E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1929128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Note: Expression is present in sperm located in the lumen of the epididymal duct.
Specimen Label: not shown
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Male
Emaps: EMAPS:3576128
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7A
Note: No expression in round or elongating spermatids.
Specimen Label: 7A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7B
Note: Expression present in elongating spermatids.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7C
Specimen Label: 7C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7D
Specimen Label: 7D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7E
Specimen Label: 7E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7F
Specimen Label: 7F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7G
Specimen Label: 7G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7H
Note: Expression is present in the testicular sperm, present at the luminal surface of the seminiferous epithelium. It is not present in cells located apically in the seminiferous epithelium.
Specimen Label: 7H
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7F
Specimen Label: 7F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7G
Specimen Label: 7G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7H
Note: Expression is present in the testicular sperm, present at the luminal surface of the seminiferous epithelium. It is not present in cells located apically in the seminiferous epithelium.
Specimen Label: 7H
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Strong
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 8/A
Note: Expression is present in sperm located in the lumen of the epididymal duct.
Specimen Label: 8/A
Detected: true
Specimen Num: 9
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Allele
Fscb<+> | MGI:3660141
 
Name: fibrous sheath CABYR binding protein; wild type
Allele Type: Not Specified
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Publication
27398160 | J:243457
First Author: Zhang X
Year: 2016
Journal: Am J Transl Res
Title: FSCB phosphorylation regulates mouse spermatozoa capacitation through suppressing SUMOylation of ROPN1/ROPN1L.
Volume: 8
Issue: 6
Pages: 2776-82
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Allele
Fscb<em1Gpt> | MGI:7299291
Name: fibrous sheath CABYR binding protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Fscb<em1(IMPC)Bay> | MGI:7425692
Name: fibrous sheath CABYR binding protein; endonuclease-mediated mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Fscb<em4Gpt> | MGI:7299292
Name: fibrous sheath CABYR binding protein; endonuclease-mediated mutation 4, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Fscb<em2Osb> | MGI:6459760
Name: fibrous sheath CABYR binding protein; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Fscb<em1Osb> | MGI:6459759
Name: fibrous sheath CABYR binding protein; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6766627 | B6;D2-Fscb<em1Osb>/Osb
Attribute String: endonuclease-mediated mutation, mutant stock
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Strain
MGI:7471754 | C57BL/6N-Fscb<em1(IMPC)Bay>/BayMmucd
Attribute String: coisogenic
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Strain
MGI:7607504 | C57BL/6NJ-Fscb<em1(IMPC)Bay>/Mmnc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Fscb/Fscb
Background: C57BL/6N-Fscb/BayMmucd
Zygosity: hm
Has Mutant Allele: true
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Publication
32588039 | J:293870
First Author: Sun J
Year: 2020
Journal: Biol Reprod
Title: CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†.
Volume: 103
Issue: 2
Pages: 183-194
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Strain
MGI:6459772 | B6;D2-Fscb<em1Osb>/Fscb<em2Osb>/Osb
Attribute String: endonuclease-mediated mutation, mutant stock
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Genotype
Genotype
Symbol: Fscb/Fscb
Background: involves: C57BL/6NJcl * DBA/2NJcl
Zygosity: ht
Has Mutant Allele: true
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Protein
A1EGX6
Organism: Mus musculus/domesticus
Length: 1074  
Fragment?: false
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Protein
E9QJV1
Organism: Mus musculus/domesticus
Length: 1062  
Fragment?: false
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Protein Domain
IPR043375 | FSCB
Type: Family
Description: Fibrous sheath CABYR (Calcium Binding Tyrosine-(Y)-Phosphorylation Regulated) binding protein (FSCB) is a testis- and sperm-specific protein that is expressed post-meiotically and localised in mouse sperm flagella. FSCB homologues are present in other mammals, including rat and human. Conserved motifs in FSCB include PXXP, proline-rich and extensin-like regions [].FSCB is regulated by protein kinase A (PKA)-mediated tryrosine phosphorylation. Its capacity of being phosphorylated and binding to calcium enhances the spermatozoa flagellar movement, spermatozoa capacitation and activation. FSCB phosphorylation activates spermatozoa motility and inhibits SUMOylation of two crucial proteins ROPN1/ROPN1L that are associated with PKA/A kinase activity and spermatozoa motility [].
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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