This entry represents a group of cys-rich proteins, including cornifelin and PLAC8 from animals, MCA (MID1-COMPLEMENTING ACTIVITY) and PCR (PLANT CADMIUM RESISTANCE) from Arabidopsis and cell number regulators from maize [, ].Cornifelin is part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia [, ]. PLAC8 is required for white adipocyte differentiation in vitro and cell number control in vivo [].Plant transports in this entry include MCA1, MCA2 and PCR1-12. MCA1 and MCA2 mediate Ca2+ uptake [, , ], while PCR2 is a zinc exporter involved in both zinc extrusion and long-distance zinc transport [].
