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Search results 501 to 521 out of 521 for Sufu

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0.019s
Type Details Score
Publication
First Author: Oh SA
Year: 2005
Journal: Curr Biol
Title: A divergent cellular role for the FUSED kinase family in the plant-specific cytokinetic phragmoplast.
Volume: 15
Issue: 23
Pages: 2107-11
Publication
First Author: Oh SA
Year: 2012
Journal: Plant J
Title: Arabidopsis Fused kinase and the Kinesin-12 subfamily constitute a signalling module required for phragmoplast expansion.
Volume: 72
Issue: 2
Pages: 308-19
Publication
First Author: Tang L
Year: 2008
Journal: Genes Dev
Title: tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.
Volume: 22
Issue: 16
Pages: 2278-90
Protein Domain
Type: Family
Description: This entry represents a group of serine/threonine-protein kinases, including Fused from fruit flies, TIO from Arabidopsis, STK36 from animals and TsuA from Dictyostelium discoideum.In Drosophila, Fused kinase is maternally required for proper segmentation during embryonic development and for the development of legs and wings during the larval stage []. STK36 is involved in the Hedgehog signaling pathway []. It is activated by the Smoothened (SMO) signal transducer, resulting in the stabilisation of GLI transcription factors and the phosphorylation of SUFU to facilitate the nuclear accumulation of GLI [, ]. In mice, STK36 is not necessary for embryonic development, although mice deficient in STK36 display growth retardation postnatally []. In Dictyostelium discoideum, TsuA is required for polarisation and chemotaxis []. In plants, TIO is tightly localised to the midline of the nascent phragmoplast and remains associated with the expanding phragmoplast ring. It plays a role in conventional modes of cytokinesis in meristems and during male gametogenesis and also acts in nonconventional modes of cytokinesis (cellularisation) during female gametogenesis [, ].
Publication
First Author: Li ZJ
Year: 2012
Journal: Development
Title: Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.
Volume: 139
Issue: 22
Pages: 4152-61
Publication
First Author: Wang Y
Year: 2024
Journal: Sci Signal
Title: TMEM216 promotes primary ciliogenesis and Hedgehog signaling through the SUFU-GLI2/GLI3 axis.
Volume: 17
Issue: 820
Pages: eabo0465
Publication
First Author: Santos N
Year: 2014
Journal: J Cell Sci
Title: A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity.
Volume: 127
Issue: Pt 7
Pages: 1500-10
Publication
First Author: Lee H
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
Volume: 480
Issue: 4
Pages: 574-579
Publication
First Author: Shi Q
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator.
Volume: 111
Issue: 52
Pages: E5651-60
Publication
First Author: Han Y
Year: 2017
Journal: PLoS Biol
Title: Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.
Volume: 15
Issue: 8
Pages: e2002063
Publication
First Author: Wijaya J
Year: 2020
Journal: Cancer Res
Title: An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.
Volume: 80
Issue: 7
Pages: 1524-1537
Publication  
First Author: Xiu C
Year: 2022
Journal: Front Cell Dev Biol
Title: Suppressor of fused-restrained Hedgehog signaling in chondrocytes is critical for epiphyseal growth plate maintenance and limb elongation in juvenile mice.
Volume: 10
Pages: 997838
Publication
First Author: Kobayashi K
Year: 2021
Journal: PLoS Genet
Title: Diverse LXG toxin and antitoxin systems specifically mediate intraspecies competition in Bacillus subtilis biofilms.
Volume: 17
Issue: 7
Pages: e1009682
Protein
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: false
Publication
First Author: Zhang S
Year: 2022
Journal: Theranostics
Title: The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
Volume: 12
Issue: 17
Pages: 7476-7490
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1048  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 1316  
Fragment?: false