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Search results 1 to 6 out of 6 for Apc

Category restricted to InteractionExperiment (x)

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Categories

Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: Myc deletion rescues Apc deficiency in the small intestine.
Interaction Experiment
Description: APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Interaction Experiment
Description: Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes.
Interaction Experiment
Description: Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2).
Interaction Experiment
Description: Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.
Interaction Experiment
Description: Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation.