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Search results 201 to 300 out of 465 for Cxcr5

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Type Details Score
Publication  
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Cyster JG
Year: 2007
Journal: MGI Direct Data Submission
Title: Generation of mice expressing a CXCR5 trasnsgene
Publication      
First Author: Cyster JG
Year: 2007
Journal: MGI Direct Data Submission
Title: Generation of secong line of CXCR5 transgenic mice
Publication  
First Author: Shen Y
Year: 2020
Journal: Neuroscience
Title: CXCR5 Knockdown Attenuates Hippocampal Neurogenesis Deficits and Cognitive Impairment in a Mouse Model of Sepsis-associated Encephalopathy.
Volume: 433
Pages: 212-220
Publication
First Author: Vaeth M
Year: 2014
Journal: J Exp Med
Title: Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Volume: 211
Issue: 3
Pages: 545-61
Publication
First Author: Neely HR
Year: 2015
Journal: J Immunol
Title: CXCL13 responsiveness but not CXCR5 expression by late transitional B cells initiates splenic white pulp formation.
Volume: 194
Issue: 6
Pages: 2616-23
Publication
First Author: Obermeier F
Year: 2003
Journal: Eur J Immunol
Title: OX40/OX40L interaction induces the expression of CXCR5 and contributes to chronic colitis induced by dextran sulfate sodium in mice.
Volume: 33
Issue: 12
Pages: 3265-74
Publication
First Author: Saito R
Year: 2005
Journal: J Neuroimmunol
Title: Altered expression of chemokine receptor CXCR5 on T cells of myasthenia gravis patients.
Volume: 170
Issue: 1-2
Pages: 172-8
Publication
First Author: Müller G
Year: 2003
Journal: Microcirculation
Title: Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking.
Volume: 10
Issue: 3-4
Pages: 325-34
Publication
First Author: Carlsen HS
Year: 2002
Journal: Gut
Title: B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue.
Volume: 51
Issue: 3
Pages: 364-71
Allele
Name: C-X-C motif chemokine receptor 5; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: C-X-C motif chemokine receptor 5; endonuclease-mediated mutation 1, Yohsuke Harada
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Allele
Name: C-X-C motif chemokine receptor 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
CL Term
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Legler DF
Year: 1998
Journal: J Exp Med
Title: B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5.
Volume: 187
Issue: 4
Pages: 655-60
Allele
Name: transgene insertion 1, Carlos Cordon-Cardo
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication  
First Author: Ma L
Year: 2021
Journal: J Exp Med
Title: ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Volume: 218
Issue: 12
Strain
Attribute String: mutant stock, transgenic
Genotype
Symbol: Cxcr5/Cxcr5<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Honda K
Year: 2001
Journal: J Exp Med
Title: Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis.
Volume: 193
Issue: 5
Pages: 621-30
Protein
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
Publication
First Author: Von Lüttichau I
Year: 2005
Journal: Stem Cells Dev
Title: Human adult CD34- progenitor cells functionally express the chemokine receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but not CXCR4.
Volume: 14
Issue: 3
Pages: 329-36
Protein Domain
Type: Family
Description: Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helper cells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).The CXC chemokine receptors are a subfamily of chemokine receptors that specifically bind and respond to cytokines of the CXC chemokine family. There are currently seven known CXC chemokine receptors in mammals, CXCR1 through to CXCR7.This entry represents CXC chemokine receptor type 5 (CXCR5), also known as cluster of differentiation 185 or Burkitt lymphoma receptor 1, which acts as a receptor for CXCL13. Upon binding to CXCR5, it causes mobilisation of intracellular calcium and chemotaxis []. CXCR5 is specifically expressed in B cells and lymphatic tissues, as well as in spleen [, ]and is expressed by human CD34(-) mesenchymal progenitor cells and immortalized mesenchymal stem cell lines [].B lymphocytes expressing CXCR5 migrate in a concentration dependent manner in response to CXCL13, which does not induce chemotaxis in T lymphocytes, monocytes or neutrophils. This selectivity for B lymphocytes is unique among the chemokines. CXCR5 also plays an essential role in B cell migration [], lymphocyte homing []and in the development of normal lymphoid tissue [, ]. It has also been shown that CD4+CXCR5+ T cells expressing CXCR5 play a protective role in the immune response against mycobacterium tuberculosis (Mtb) infection, highlighting a potential use for TB vaccine design and therapy [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Phares TW
Year: 2016
Journal: Brain Behav Immun
Title: CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis.
Volume: 54
Pages: 128-139
Publication
First Author: Weiss JM
Year: 2016
Journal: Oncotarget
Title: Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.
Volume: 7
Issue: 7
Pages: 7550-62
Publication      
First Author: Wang KW
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for ice
Publication
First Author: Bagaeva LV
Year: 2006
Journal: J Immunol
Title: CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis.
Volume: 176
Issue: 12
Pages: 7676-85
Publication
First Author: Ansel KM
Year: 2002
Journal: Immunity
Title: CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity.
Volume: 16
Issue: 1
Pages: 67-76
Publication
First Author: Colombo MJ
Year: 2010
Journal: Infect Immun
Title: T-cell-independent immune responses do not require CXC ligand 13-mediated B1 cell migration.
Volume: 78
Issue: 9
Pages: 3950-6
Publication
First Author: Ebisuno Y
Year: 2003
Journal: J Immunol
Title: Cutting edge: the B cell chemokine CXC chemokine ligand 13/B lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules.
Volume: 171
Issue: 4
Pages: 1642-6
Publication
First Author: Suto H
Year: 2009
Journal: Int Immunol
Title: CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways.
Volume: 21
Issue: 4
Pages: 467-76
GXD Expression    
Probe: MGI:7547074
Assay Type: RT-PCR
Annotation Date: 2023-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7547089
Age: embryonic day 16.5
Image: 3
Specimen Label: H2A.Z.2 fl/fl
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7547074
Assay Type: RT-PCR
Annotation Date: 2023-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7547089
Age: embryonic day 16.5
Image: 3
Specimen Label: H2A.Z.2 cKO(Nes)
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 1
Specimen Label: 1M
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 1
Specimen Label: 1M
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 2
Specimen Label: 2M
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 2
Specimen Label: 2M
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 3
Specimen Label: 3M
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 3
Specimen Label: 3M
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 4
Specimen Label: 4M
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3579434
Assay Type: RT-PCR
Annotation Date: 2005-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3581130
Age: postnatal month 4
Specimen Label: 4M
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945744
Age: embryonic day 11.5
Image: g01408 E11.5
Specimen Label: g01408 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945744
Age: embryonic day 15.5
Image: g01408 E15.5
Specimen Label: g01408 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945744
Age: embryonic day 15.5
Image: g01408 E15.5
Specimen Label: g01408 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945744
Age: postnatal day 7
Image: g01408 P7
Specimen Label: g01408 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945744
Age: postnatal day 42
Image: g01408 Adult
Specimen Label: g01408 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945744
Age: embryonic day 11.5
Image: g01408 E11.5
Specimen Label: g01408 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945744
Age: embryonic day 15.5
Image: g01408 E15.5
Specimen Label: g01408 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945744
Age: postnatal day 7
Image: g01408 P7
Note: Expression was region specific and scattered.
Specimen Label: g01408 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945744
Age: postnatal day 42
Image: g01408 Adult
Specimen Label: g01408 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5638397
Assay Type: RNA in situ
Annotation Date: 2015-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1902825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5638404
Age: embryonic day 17.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4884929
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716823
Stage: TS23
Assay Id: MGI:4945744
Age: embryonic day 15.5
Image: g01408 E15.5
Specimen Label: g01408 E15.5
Detected: false
Specimen Num: 2