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Search results 201 to 300 out of 686 for Mdm2

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Category: Publication
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Type Details Score
Publication
16018998 | J:102790
First Author: Sakurai T
Year: 2005
Journal: Exp Cell Res
Title: Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro.
Volume: 309
Issue: 2
Pages: 264-72
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Publication
26883797 | J:250113
 
First Author: Maruyama EO
Year: 2016
Journal: Sci Rep
Title: Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development.
Volume: 6
Pages: 20999
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Publication
29581288 | J:261387
First Author: Burke RM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.
Volume: 115
Issue: 15
Pages: E3436-E3445
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Publication
30175854 | J:267822
First Author: Wang Y
Year: 2018
Journal: J Pathol
Title: HMGA2 promotes intestinal tumorigenesis by facilitating MDM2-mediated ubiquitination and degradation of p53.
Volume: 246
Issue: 4
Pages: 508-518
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Publication
27912078 | J:240039
First Author: Zhang CX
Year: 2017
Journal: Am J Pathol
Title: Mouse Double Minute 2 Actively Suppresses p53 Activity in Oocytes during Mouse Folliculogenesis.
Volume: 187
Issue: 2
Pages: 339-351
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Publication
30131393 | J:266066
First Author: Liu Z
Year: 2018
Journal: Diabetes
Title: The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy.
Volume: 67
Issue: 11
Pages: 2397-2409
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Publication
27364741 | J:235222
First Author: Livera G
Year: 2016
Journal: FEBS Lett
Title: Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.
Volume: 590
Issue: 16
Pages: 2566-74
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Publication
22835827 | J:192387
First Author: Roudier E
Year: 2012
Journal: FASEB J
Title: Murine double minute-2 expression is required for capillary maintenance and exercise-induced angiogenesis in skeletal muscle.
Volume: 26
Issue: 11
Pages: 4530-9
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Publication
24339722 | J:211856
 
First Author: Jaramillo-Rangel G
Year: 2013
Journal: Mol Vis
Title: p53 E3 ubiquitin protein ligase homolog regulates p53 in vivo in the adult mouse eye lens.
Volume: 19
Pages: 2468-76
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Publication
7651732 | J:28318
First Author: Knippschild U
Year: 1995
Journal: Oncogene
Title: Cell-specific transcriptional activation of the mdm2-gene by ectopically expressed wild-type form of a temperature-sensitive mutant p53.
Volume: 11
Issue: 4
Pages: 683-90
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Publication
12944468 | J:85465
First Author: O'Keefe K
Year: 2003
Journal: Mol Cell Biol
Title: Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination.
Volume: 23
Issue: 18
Pages: 6396-405
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Publication
18206965 | J:180459
First Author: Lim ST
Year: 2008
Journal: Mol Cell
Title: Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation.
Volume: 29
Issue: 1
Pages: 9-22
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Publication
15989966 | J:99711
First Author: Yuan X
Year: 2005
Journal: Mol Cell
Title: Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.
Volume: 19
Issue: 1
Pages: 77-87
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Publication
25981963 | J:242745
First Author: Joshi Y
Year: 2015
Journal: Brain
Title: The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
Volume: 138
Issue: Pt 7
Pages: 1843-62
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Publication
26255629 | J:309499
First Author: Goh AM
Year: 2015
Journal: Oncotarget
Title: Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice.
Volume: 6
Issue: 20
Pages: 17968-80
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Publication
18359851 | J:133357
First Author: Abe Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.
Volume: 105
Issue: 12
Pages: 4838-43
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Publication
34257081 | J:317166
First Author: Mohibi S
Year: 2021
Journal: Mol Cancer Res
Title: Mice Deficient in the RNA-Binding Protein Zfp871 Are Prone to Early Death and Steatohepatitis in Part through the p53-Mdm2 Axis.
Volume: 19
Issue: 10
Pages: 1751-1762
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Publication
22805162 | J:244031
First Author: Pan D
Year: 2012
Journal: Aging Cell
Title: SnoN activates p53 directly to regulate aging and tumorigenesis.
Volume: 11
Issue: 5
Pages: 902-911
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Publication
14767071 | J:90021
First Author: Mesaeli N
Year: 2004
Journal: Mol Biol Cell
Title: Impaired p53 expression, function, and nuclear localization in calreticulin-deficient cells.
Volume: 15
Issue: 4
Pages: 1862-70
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Publication
30260703 | J:283715
First Author: Haraguchi H
Year: 2019
Journal: FASEB J
Title: Mdm2-p53-SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality.
Volume: 33
Issue: 2
Pages: 2610-2620
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Publication
10341712 | J:51883
First Author: Prives C
Year: 1999
Journal: J Pathol
Title: The p53 pathway.
Volume: 187
Issue: 1
Pages: 112-26
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Publication
21211512 | J:169240
First Author: You A
Year: 2011
Journal: Arch Biochem Biophys
Title: Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2.
Volume: 507
Issue: 2
Pages: 356-64
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Publication
21738215 | J:203618
First Author: Thotala DK
Year: 2012
Journal: Cell Death Differ
Title: Glycogen synthase kinase 3β inhibitors protect hippocampal neurons from radiation-induced apoptosis by regulating MDM2-p53 pathway.
Volume: 19
Issue: 3
Pages: 387-96
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Publication
36198274 | J:329967
First Author: Li H
Year: 2022
Journal: Cell Rep
Title: Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.
Volume: 41
Issue: 1
Pages: 111435
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Publication
10205143 | J:54842
First Author: Leri A
Year: 1999
Journal: Circ Res
Title: Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.
Volume: 84
Issue: 7
Pages: 752-62
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Publication
30578299 | J:275335
First Author: Xi G
Year: 2019
Journal: J Biol Chem
Title: Hyperglycemia induces vascular smooth muscle cell dedifferentiation by suppressing insulin receptor substrate-1-mediated p53/KLF4 complex stabilization.
Volume: 294
Issue: 7
Pages: 2407-2421
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Publication
21849563 | J:176050
First Author: Bianchetta MJ
Year: 2011
Journal: J Neurosci
Title: Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons.
Volume: 31
Issue: 33
Pages: 12029-35
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Publication
21183956 | J:186966
First Author: Jiang M
Year: 2011
Journal: Cell Death Differ
Title: SUMO-specific protease 2 in Mdm2-mediated regulation of p53.
Volume: 18
Issue: 6
Pages: 1005-15
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Publication
20697359 | J:170004
First Author: Giglio S
Year: 2010
Journal: Oncogene
Title: Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
Volume: 29
Issue: 44
Pages: 5935-45
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Publication
21747916 | J:174526
First Author: Pan W
Year: 2011
Journal: PLoS One
Title: The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.
Volume: 6
Issue: 6
Pages: e21625
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Publication
14695178 | J:87065
First Author: Chavez-Reyes A
Year: 2003
Journal: Cancer Res
Title: Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
Volume: 63
Issue: 24
Pages: 8664-9
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21730163 | J:174359
First Author: Huang L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo.
Volume: 108
Issue: 29
Pages: 12001-6
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Publication
31409715 | J:283603
First Author: Pant V
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity.
Volume: 116
Issue: 35
Pages: 17429-17437
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Publication
37213079 | J:336094
 
First Author: Zheng H
Year: 2023
Journal: Development
Title: CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation.
Volume: 150
Issue: 10
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Publication
11172041 | J:67553
First Author: Ruland J
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.
Volume: 98
Issue: 4
Pages: 1859-64
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Publication
16129783 | J:100984
First Author: Mekhail K
Year: 2005
Journal: J Cell Biol
Title: Regulation of ubiquitin ligase dynamics by the nucleolus.
Volume: 170
Issue: 5
Pages: 733-44
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Publication
15678128 | J:96269
First Author: Saito A
Year: 2005
Journal: J Cereb Blood Flow Metab
Title: Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress.
Volume: 25
Issue: 2
Pages: 267-80
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Publication
18614532 | J:142015
First Author: Zhang G
Year: 2008
Journal: J Biol Chem
Title: Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
Volume: 283
Issue: 36
Pages: 24343-58
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18923161 | J:145784
First Author: Jin XL
Year: 2009
Journal: Biol Reprod
Title: Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.
Volume: 80
Issue: 2
Pages: 286-94
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Publication
20855528 | J:317403
First Author: De Clercq S
Year: 2010
Journal: Mol Cell Biol
Title: Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.
Volume: 30
Issue: 22
Pages: 5394-405
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Publication
22889954 | J:316577
First Author: Furlan A
Year: 2012
Journal: J Hepatol
Title: Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver.
Volume: 57
Issue: 6
Pages: 1292-8
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Publication
35696550 | J:327832
First Author: Makino Y
Year: 2022
Journal: Cancer Res
Title: Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non-Cell Autonomous Liver Carcinogenesis.
Volume: 82
Issue: 16
Pages: 2860-2873
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Publication
30872705 | J:275626
First Author: Anamthathmakula P
Year: 2019
Journal: Sci Rep
Title: Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination.
Volume: 9
Issue: 1
Pages: 4452
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Publication
26470726 | J:258502
First Author: Fouchécourt S
Year: 2016
Journal: Cell Death Differ
Title: Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility.
Volume: 23
Issue: 3
Pages: 521-30
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Publication
28181574 | J:275301
 
First Author: Laos M
Year: 2017
Journal: Sci Rep
Title: Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development.
Volume: 7
Pages: 42216
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Publication
17893884 | J:145221
First Author: Liu G
Year: 2007
Journal: J Pathol
Title: The p53-Mdm2 network in progenitor cell expansion during mouse postnatal development.
Volume: 213
Issue: 4
Pages: 360-8
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Publication
28049824 | J:239540
First Author: Zhang G
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: p53 pathway is involved in cell competition during mouse embryogenesis.
Volume: 114
Issue: 3
Pages: 498-503
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Publication
22237799 | J:183431
First Author: Aboudehen K
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Mechanisms of p53 activation and physiological relevance in the developing kidney.
Volume: 302
Issue: 8
Pages: F928-40
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Publication
16884701 | J:112569
First Author: Golestaneh N
Year: 2006
Journal: Brain Res
Title: Cell cycle deregulation and loss of stem cell phenotype in the subventricular zone of TGF-beta adaptor elf-/- mouse brain.
Volume: 1108
Issue: 1
Pages: 45-53
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21857681 | J:176251
First Author: Hara MR
Year: 2011
Journal: Nature
Title: A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.
Volume: 477
Issue: 7364
Pages: 349-53
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Publication
31534052 | J:284759
 
First Author: Li Q
Year: 2019
Journal: JCI Insight
Title: Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.
Volume: 4
Issue: 18
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37612280 | J:339368
First Author: Yao F
Year: 2023
Journal: Cell Death Dis
Title: Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis.
Volume: 14
Issue: 8
Pages: 543
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Publication
36012294 | J:327815
 
First Author: Beauchamp MC
Year: 2022
Journal: Int J Mol Sci
Title: Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion.
Volume: 23
Issue: 16
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22714890 | J:213978
First Author: Vuong L
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina.
Volume: 53
Issue: 8
Pages: 4821-31
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Publication
32464196 | J:300508
 
First Author: Hilliard SA
Year: 2020
Journal: Mech Dev
Title: Mdm4 controls ureteric bud branching via regulation of p53 activity.
Volume: 163
Pages: 103616
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31018144 | J:325272
First Author: Teo YV
Year: 2019
Journal: Cell Rep
Title: Notch Signaling Mediates Secondary Senescence.
Volume: 27
Issue: 4
Pages: 997-1007.e5
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28122227 | J:254345
First Author: Liu S
Year: 2017
Journal: Cell Rep
Title: Protection against High-Fat-Diet-Induced Obesity in MDM2C305F Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.
Volume: 18
Issue: 4
Pages: 1005-1018
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10365438 | J:55449
First Author: Berberich SJ
Year: 1999
Journal: Differentiation
Title: mdm-2 gene amplification in 3T3-L1 preadipocytes.
Volume: 64
Issue: 4
Pages: 205-12
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17245556 | J:123650
First Author: Schuster K
Year: 2007
Journal: Transgenic Res
Title: Selection for mutations in the cDNAs of transgenic mice upon expression of an embryonic lethal protein.
Volume: 16
Issue: 4
Pages: 527-30
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3474784 | J:8787
First Author: Cahilly-Snyder L
Year: 1987
Journal: Somat Cell Mol Genet
Title: Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line.
Volume: 13
Issue: 3
Pages: 235-44
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25057989 | J:219006
First Author: Ito TK
Year: 2014
Journal: PLoS One
Title: A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis.
Volume: 9
Issue: 7
Pages: e102186
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25987256 | J:226651
First Author: Jaako P
Year: 2015
Journal: Leukemia
Title: Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
Volume: 29
Issue: 11
Pages: 2221-9
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7472488 | J:29785
First Author: Ye P
Year: 1995
Journal: J Neurosci
Title: In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice.
Volume: 15
Issue: 11
Pages: 7344-56
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18695251 | J:248554
First Author: Han JM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53.
Volume: 105
Issue: 32
Pages: 11206-11
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19536131 | J:150839
First Author: Lee EW
Year: 2009
Journal: EMBO J
Title: Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis.
Volume: 28
Issue: 14
Pages: 2100-13
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25823025 | J:332564
First Author: Meng X
Year: 2015
Journal: Oncogene
Title: Oncogenic c-Myc-induced lymphomagenesis is inhibited non-redundantly by the p19Arf-Mdm2-p53 and RP-Mdm2-p53 pathways.
Volume: 34
Issue: 46
Pages: 5709-17
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27402081 | J:234915
First Author: Meng X
Year: 2016
Journal: Cancer Res
Title: RPL23 Links Oncogenic RAS Signaling to p53-Mediated Tumor Suppression.
Volume: 76
Issue: 17
Pages: 5030-9
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19573810 | J:150341
First Author: Wang YV
Year: 2009
Journal: Cancer Cell
Title: Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases.
Volume: 16
Issue: 1
Pages: 33-43
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21852537 | J:174671
First Author: Garcia D
Year: 2011
Journal: Genes Dev
Title: Validation of MdmX as a therapeutic target for reactivating p53 in tumors.
Volume: 25
Issue: 16
Pages: 1746-57
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23770245 | J:199308
First Author: Simeonova I
Year: 2013
Journal: Cell Rep
Title: Mutant mice lacking the p53 C-terminal domain model telomere syndromes.
Volume: 3
Issue: 6
Pages: 2046-58
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31483066 | J:282255
First Author: Timofeev O
Year: 2019
Journal: EMBO J
Title: Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses.
Volume: 38
Issue: 20
Pages: e102096
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29364875 | J:257747
First Author: Calo E
Year: 2018
Journal: Nature
Title: Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.
Volume: 554
Issue: 7690
Pages: 112-117
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35931383 | J:333906
First Author: Qiu H
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis.
Volume: 14
Issue: 5
Pages: 1003-1023
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34303799 | J:317283
 
First Author: Liu DC
Year: 2021
Journal: Neurobiol Dis
Title: ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model.
Volume: 158
Pages: 105450
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29950602 | J:266532
First Author: Li Y
Year: 2018
Journal: Nat Commun
Title: Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome.
Volume: 9
Issue: 1
Pages: 2494
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34628485 | J:322179
First Author: Humpton TJ
Year: 2022
Journal: Cell Death Differ
Title: p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4.
Volume: 29
Issue: 3
Pages: 514-526
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Publication
21747166 | J:176163
First Author: Kodama T
Year: 2011
Journal: J Clin Invest
Title: Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice.
Volume: 121
Issue: 8
Pages: 3343-56
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Publication
21285512 | J:171821
First Author: Wang Y
Year: 2011
Journal: J Clin Invest
Title: Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation.
Volume: 121
Issue: 3
Pages: 893-904
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Publication
20671749 | J:186335
First Author: Lee MK
Year: 2011
Journal: Cell Death Differ
Title: Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo.
Volume: 18
Issue: 2
Pages: 214-21
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Publication
27829155 | J:242330
First Author: Klusmann I
Year: 2016
Journal: Cell Rep
Title: p53 Activity Results in DNA Replication Fork Processivity.
Volume: 17
Issue: 7
Pages: 1845-1857
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Publication
27617574 | J:236456
First Author: Liu S
Year: 2017
Journal: Oncogene
Title: Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.
Volume: 36
Issue: 10
Pages: 1374-1383
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Publication
35320355 | J:324785
First Author: Xiong S
Year: 2022
Journal: Cancer Res
Title: Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.
Volume: 82
Issue: 10
Pages: 1926-1936
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Publication
20849854 | J:165421
First Author: Yan J
Year: 2010
Journal: FEBS Lett
Title: Overexpression of SCYL1-BP1 stabilizes functional p53 by suppressing MDM2-mediated ubiquitination.
Volume: 584
Issue: 20
Pages: 4319-24
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Publication
33637564 | J:305549
First Author: Jeffers JR
Year: 2021
Journal: Cancer Res
Title: The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model.
Volume: 81
Issue: 9
Pages: 2442-2456
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•
•
•
•
Publication
22789538 | J:187617
First Author: Bywater MJ
Year: 2012
Journal: Cancer Cell
Title: Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Volume: 22
Issue: 1
Pages: 51-65
•
•
•
•
•
Publication
1552940 | J:1999
First Author: Donehower LA
Year: 1992
Journal: Nature
Title: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours.
Volume: 356
Issue: 6366
Pages: 215-21
•
•
•
•
•
Publication
11718560 | J:72910
First Author: Bothner B
Year: 2001
Journal: J Mol Biol
Title: Defining the molecular basis of Arf and Hdm2 interactions.
Volume: 314
Issue: 2
Pages: 263-77
•
•
•
•
•
Publication
22262176 | J:240382
First Author: Morgado-Palacin L
Year: 2012
Journal: Cell Cycle
Title: Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells.
Volume: 11
Issue: 3
Pages: 503-10
•
•
•
•
•
Publication
1535557 | J:1336
First Author: Momand J
Year: 1992
Journal: Cell
Title: The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation.
Volume: 69
Issue: 7
Pages: 1237-45
•
•
•
•
•
Publication
8152809 | J:17852
First Author: Berberich S
Year: 1994
Journal: Oncogene
Title: The mdm-2 oncogene is translocated and overexpressed in a murine plasmacytoma cell line expressing wild-type p53.
Volume: 9
Issue: 5
Pages: 1469-72
•
•
•
•
•
Publication
17823617 | J:142171
First Author: Benosman S
Year: 2007
Journal: Cell Death Differ
Title: Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis.
Volume: 14
Issue: 12
Pages: 2047-57
•
•
•
•
•
Publication
19521340 | J:150846
First Author: Mancini F
Year: 2009
Journal: EMBO J
Title: MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway.
Volume: 28
Issue: 13
Pages: 1926-39
•
•
•
•
•
Publication
19247369 | J:164188
First Author: Gama V
Year: 2009
Journal: Cell Death Differ
Title: Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.
Volume: 16
Issue: 5
Pages: 758-69
•
•
•
•
•
Publication
19590512 | J:169283
First Author: Du W
Year: 2009
Journal: Cell Death Differ
Title: Suppression of p53 activity by Siva1.
Volume: 16
Issue: 11
Pages: 1493-504
•
•
•
•
•
Publication
20542919 | J:173420
First Author: Zhang Y
Year: 2010
Journal: Nucleic Acids Res
Title: Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26.
Volume: 38
Issue: 19
Pages: 6544-54
•
•
•
•
•
Publication
24174547 | J:211902
First Author: Bai D
Year: 2014
Journal: Nucleic Acids Res
Title: Regulation of the HDM2-p53 pathway by ribosomal protein L6 in response to ribosomal stress.
Volume: 42
Issue: 3
Pages: 1799-811
•
•
•
•
•
Publication
9843989 | J:72144
First Author: DeJarnette JB
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Specific requirement for CD3epsilon in T cell development.
Volume: 95
Issue: 25
Pages: 14909-14
•
•
•
•
•
Publication
19151705 | J:146960
First Author: Nishiyama M
Year: 2009
Journal: Nat Cell Biol
Title: CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.
Volume: 11
Issue: 2
Pages: 172-82
•
•
•
•
•
Publication
19556538 | J:150816
First Author: Allton K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Trim24 targets endogenous p53 for degradation.
Volume: 106
Issue: 28
Pages: 11612-6
•
•
•
•
•
Publication
21674502 | J:174216
First Author: Terzian T
Year: 2011
Journal: J Pathol
Title: Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.
Volume: 224
Issue: 4
Pages: 540-52
•
•
•
•
•




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