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Search results 1 to 100 out of 334 for Brca2

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Category: Publication
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Type Details Score
Publication
8673099 | -
First Author: Bork P
Year: 1996
Journal: Nat Genet
Title: Internal repeats in the BRCA2 protein sequence.
Volume: 13
Issue: 1
Pages: 22-3
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Publication
9811893 | -
First Author: Marmorstein LY
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The BRCA2 gene product functionally interacts with p53 and RAD51.
Volume: 95
Issue: 23
Pages: 13869-74
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Publication
9560268 | -
First Author: Chen PL
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment.
Volume: 95
Issue: 9
Pages: 5287-92
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Publication
9405383 | -
First Author: Wong AK
Year: 1997
Journal: J Biol Chem
Title: RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2.
Volume: 272
Issue: 51
Pages: 31941-4
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Publication
10551859 | -
First Author: Chen CF
Year: 1999
Journal: J Biol Chem
Title: Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control.
Volume: 274
Issue: 46
Pages: 32931-5
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Publication
12228710 | J:114800
First Author: Yang H
Year: 2002
Journal: Science
Title: BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Volume: 297
Issue: 5588
Pages: 1837-48
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Publication
22077663 | -
First Author: Seeliger K
Year: 2012
Journal: New Phytol
Title: BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana.
Volume: 193
Issue: 2
Pages: 364-75
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Publication
27490902 | J:234167
First Author: Hartford SA
Year: 2016
Journal: PLoS Genet
Title: Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.
Volume: 12
Issue: 8
Pages: e1006236
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Publication
20513136 | -
First Author: Walker LC
Year: 2010
Journal: Hum Mutat
Title: Detection of splicing aberrations caused by BRCA1 and BRCA2 sequence variants encoding missense substitutions: implications for prediction of pathogenicity.
Volume: 31
Issue: 6
Pages: E1484-505
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Publication
11597317 | J:114008
First Author: Orelli BJ
Year: 2001
Journal: Breast Cancer Res
Title: BRCA2 and homologous recombination.
Volume: 3
Issue: 5
Pages: 294-8
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Publication
19047179 | J:142088
First Author: Philip S
Year: 2008
Journal: Cancer Res
Title: Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications.
Volume: 68
Issue: 23
Pages: 9973-81
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Publication
30760716 | J:273173
First Author: Zhang J
Year: 2019
Journal: Nat Commun
Title: A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination.
Volume: 10
Issue: 1
Pages: 722
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Publication
9660919 | J:47362
First Author: Patel KJ
Year: 1998
Journal: Mol Cell
Title: Involvement of Brca2 in DNA repair.
Volume: 1
Issue: 3
Pages: 347-57
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Publication
27498558 | J:241267
 
First Author: Ding X
Year: 2016
Journal: Nat Commun
Title: Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.
Volume: 7
Pages: 12425
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Publication
11343905 | J:114055
First Author: Venkitaraman AR
Year: 2001
Journal: Curr Opin Cell Biol
Title: Chromosome stability, DNA recombination and the BRCA2 tumour suppressor.
Volume: 13
Issue: 3
Pages: 338-43
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Publication
12410562 | J:141600
First Author: Flores KG
Year: 2002
Journal: Mol Carcinog
Title: Thymic model for examining BRCA2 expression and function.
Volume: 35
Issue: 3
Pages: 103-9
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Publication
14981540 | J:89083
First Author: Yan DH
Year: 2004
Journal: Oncogene
Title: A delayed chemically induced tumorigenesis in Brca2 mutant mice.
Volume: 23
Issue: 10
Pages: 1896-901
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Publication
12242698 | J:115553
First Author: Daniel DC
Year: 2002
Journal: Microsc Res Tech
Title: Highlight: BRCA1 and BRCA2 proteins in breast cancer.
Volume: 59
Issue: 1
Pages: 68-83
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Publication
16108063 | J:101017
First Author: Henderson BR
Year: 2005
Journal: Bioessays
Title: Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking.
Volume: 27
Issue: 9
Pages: 884-93
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Publication
12442171 | -
First Author: Pellegrini L
Year: 2002
Journal: Nature
Title: Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.
Volume: 420
Issue: 6913
Pages: 287-93
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Publication
12140683 | J:78538
First Author: Callens N
Year: 2002
Journal: Mamm Genome
Title: Genomic organization and expression of the mouse Brca2 gene.
Volume: 13
Issue: 7
Pages: 352-8
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Publication
10819537 | J:62421
First Author: Hakem R
Year: 1998
Journal: J Mammary Gland Biol Neoplasia
Title: Developmental studies of Brca1 and Brca2 knock-out mice.
Volume: 3
Issue: 4
Pages: 431-45
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Publication
9002670 | J:38519
First Author: Bignell G
Year: 1997
Journal: Hum Mol Genet
Title: The BRC repeats are conserved in mammalian BRCA2 proteins.
Volume: 6
Issue: 1
Pages: 53-8
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Publication
25666348 | J:232670
First Author: Jeong JH
Year: 2015
Journal: Mol Cells
Title: Brca2 deficiency leads to T cell loss and immune dysfunction.
Volume: 38
Issue: 3
Pages: 251-8
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Publication
14660434 | J:87231
First Author: Sharan SK
Year: 2004
Journal: Development
Title: BRCA2 deficiency in mice leads to meiotic impairment and infertility.
Volume: 131
Issue: 1
Pages: 131-42
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Publication
22157755 | J:182460
First Author: Singh KK
Year: 2012
Journal: J Biol Chem
Title: BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure.
Volume: 287
Issue: 9
Pages: 6604-14
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Publication
26338419 | J:238472
First Author: Jiang Q
Year: 2015
Journal: Genes Dev
Title: MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.
Volume: 29
Issue: 18
Pages: 1955-68
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Publication
31242413 | J:294372
First Author: Brandsma I
Year: 2019
Journal: Cell Rep
Title: HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Volume: 27
Issue: 13
Pages: 3790-3798.e7
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Publication
25043256 | J:215920
First Author: Xu H
Year: 2014
Journal: J Pathol
Title: Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells.
Volume: 234
Issue: 3
Pages: 386-97
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Publication
17476307 | J:122559
First Author: Frappart PO
Year: 2007
Journal: EMBO J
Title: BRCA2 is required for neurogenesis and suppression of medulloblastoma.
Volume: 26
Issue: 11
Pages: 2732-42
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Publication
9171369 | J:40595
First Author: Suzuki A
Year: 1997
Journal: Genes Dev
Title: Brca2 is required for embryonic cellular proliferation in the mouse.
Volume: 11
Issue: 10
Pages: 1242-52
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Publication
22340495 | J:181473
First Author: Choi E
Year: 2012
Journal: Dev Cell
Title: BRCA2 fine-tunes the spindle assembly checkpoint through reinforcement of BubR1 acetylation.
Volume: 22
Issue: 2
Pages: 295-308
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Publication
11494122 | J:70564
First Author: Ludwig T
Year: 2001
Journal: Oncogene
Title: Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice.
Volume: 20
Issue: 30
Pages: 3937-48
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Publication
31209201 | J:324078
First Author: Miao Y
Year: 2019
Journal: Cell Death Dis
Title: BRCA2 deficiency is a potential driver for human primary ovarian insufficiency.
Volume: 10
Issue: 7
Pages: 474
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Publication
30811824 | J:292589
First Author: Kwon MS
Year: 2019
Journal: FEBS J
Title: Brca2 abrogation engages with the alternative lengthening of telomeres via break-induced replication.
Volume: 286
Issue: 10
Pages: 1841-1858
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Publication
28904335 | J:252453
First Author: Feng W
Year: 2017
Journal: Nat Commun
Title: BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination.
Volume: 8
Issue: 1
Pages: 525
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Publication
12483515 | J:81094
First Author: Moynahan ME
Year: 2002
Journal: Oncogene
Title: The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans.
Volume: 21
Issue: 58
Pages: 8994-9007
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Publication
9242436 | J:41969
First Author: McAllister KA
Year: 1997
Journal: Cancer Res
Title: Characterization of the rat and mouse homologues of the BRCA2 breast cancer susceptibility gene.
Volume: 57
Issue: 15
Pages: 3121-5
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9699678 | J:49518
First Author: Morimatsu M
Year: 1998
Journal: Cancer Res
Title: Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to gamma-radiation and premature senescence.
Volume: 58
Issue: 15
Pages: 3441-7
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Publication
31877165 | J:283370
First Author: Park D
Year: 2019
Journal: PLoS One
Title: Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.
Volume: 14
Issue: 12
Pages: e0226714
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Publication
20585617 | J:161511
First Author: Francis JC
Year: 2010
Journal: PLoS Genet
Title: Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.
Volume: 6
Issue: 6
Pages: e1000995
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Publication
18587272 | J:140433
First Author: Park PG
Year: 2008
Journal: Exp Mol Med
Title: Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus.
Volume: 40
Issue: 3
Pages: 339-44
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Publication
9398843 | J:44386
First Author: Connor F
Year: 1997
Journal: Nat Genet
Title: Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation.
Volume: 17
Issue: 4
Pages: 423-30
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14681210 | J:87195
First Author: Lomonosov M
Year: 2003
Journal: Genes Dev
Title: Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein.
Volume: 17
Issue: 24
Pages: 3017-22
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Publication
34326328 | J:322962
First Author: Ghouil R
Year: 2021
Journal: Nat Commun
Title: BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Volume: 12
Issue: 1
Pages: 4605
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Publication
11861370 | J:75026
First Author: McAllister KA
Year: 2002
Journal: Cancer Res
Title: Cancer susceptibility of mice with a homozygous deletion in the COOH-terminal domain of the Brca2 gene.
Volume: 62
Issue: 4
Pages: 990-4
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Publication
9063750 | J:38616
First Author: Connor F
Year: 1997
Journal: Hum Mol Genet
Title: Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.
Volume: 6
Issue: 2
Pages: 291-300
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11172592 | J:74101
First Author: Bernard-Gallon DJ
Year: 2001
Journal: Int J Oncol
Title: Brca1 and Brca2 protein expression patterns in different tissues of murine origin.
Volume: 18
Issue: 2
Pages: 271-80
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Publication
9467943 | J:45456
First Author: Blackshear PE
Year: 1998
Journal: Oncogene
Title: Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice.
Volume: 16
Issue: 1
Pages: 61-8
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Publication
27779185 | J:242647
 
First Author: Kass EM
Year: 2016
Journal: Nat Commun
Title: Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation.
Volume: 7
Pages: 13241
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Publication
11207365 | J:67272
First Author: Marmorstein LY
Year: 2001
Journal: Cell
Title: A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression.
Volume: 104
Issue: 2
Pages: 247-57
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Publication
22187435 | J:182445
First Author: Min J
Year: 2012
Journal: J Biol Chem
Title: The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis.
Volume: 287
Issue: 7
Pages: 5091-101
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37980415 | J:342841
First Author: Mishra AP
Year: 2023
Journal: Cell Death Dis
Title: Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant.
Volume: 14
Issue: 11
Pages: 753
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Publication
21719596 | J:176900
First Author: Biswas K
Year: 2011
Journal: Blood
Title: A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay.
Volume: 118
Issue: 9
Pages: 2430-42
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8917547 | J:36562
First Author: Rajan JV
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells.
Volume: 93
Issue: 23
Pages: 13078-83
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11694875 | J:73028
First Author: Jonkers J
Year: 2001
Journal: Nat Genet
Title: Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.
Volume: 29
Issue: 4
Pages: 418-25
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32980867 | J:305816
First Author: Chen X
Year: 2020
Journal: Cell Death Dis
Title: Brca2 deficiency drives gastrointestinal tumor formation and is selectively inhibited by mitomycin C.
Volume: 11
Issue: 9
Pages: 812
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21056012 | J:166678
First Author: Skoulidis F
Year: 2010
Journal: Cancer Cell
Title: Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer.
Volume: 18
Issue: 5
Pages: 499-509
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Publication
11477095 | J:72374
First Author: Sarkisian CJ
Year: 2001
Journal: J Biol Chem
Title: Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals.
Volume: 276
Issue: 40
Pages: 37640-8
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Publication
11215675 | J:67445
First Author: Bennett LM
Year: 2001
Journal: Toxicol Pathol
Title: Mammary tumor induction and premature ovarian failure in ApcMin mice are not enhanced by Brca2 deficiency.
Volume: 29
Issue: 1
Pages: 117-25
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Publication
21076401 | J:228560
First Author: Badie S
Year: 2010
Journal: Nat Struct Mol Biol
Title: BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
Volume: 17
Issue: 12
Pages: 1461-9
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12414647 | J:79697
First Author: Cheung AM
Year: 2002
Journal: Cancer Res
Title: Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.
Volume: 62
Issue: 21
Pages: 6194-204
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9021166 | J:38230
First Author: Sharan SK
Year: 1997
Journal: Mamm Genome
Title: Identification and characterization of a microsatellite marker within murine Brca2 gene.
Volume: 8
Issue: 1
Pages: 79
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12619154 | J:82434
First Author: Donoho G
Year: 2003
Journal: Genes Chromosomes Cancer
Title: Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.
Volume: 36
Issue: 4
Pages: 317-31
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15735671 | J:98772
First Author: Hay T
Year: 2005
Journal: Oncogene
Title: Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells.
Volume: 24
Issue: 23
Pages: 3842-6
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Publication
22678057 | J:187434
First Author: Biswas K
Year: 2012
Journal: Hum Mol Genet
Title: Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.
Volume: 21
Issue: 18
Pages: 3993-4006
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16546942 | J:109193
First Author: McAllister KA
Year: 2006
Journal: Toxicol Pathol
Title: Spontaneous and irradiation-induced tumor susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutation.
Volume: 34
Issue: 2
Pages: 187-98
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Publication
15026330 | J:89150
First Author: Cheung AM
Year: 2004
Journal: Cancer Res
Title: Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53(+/-) mutant mice.
Volume: 64
Issue: 6
Pages: 1959-65
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Publication
29718910 | J:263685
First Author: Kitami K
Year: 2018
Journal: PLoS Genet
Title: BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development.
Volume: 14
Issue: 5
Pages: e1007340
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9774970 | J:113839
First Author: Chen J
Year: 1998
Journal: Mol Cell
Title: Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
Volume: 2
Issue: 3
Pages: 317-28
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Publication
10910057 | J:206999
First Author: Bennett LM
Year: 2000
Journal: Cancer Res
Title: Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol.
Volume: 60
Issue: 13
Pages: 3461-9
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Publication
36906610 | J:334068
First Author: Tomaszowski KH
Year: 2023
Journal: Nat Commun
Title: Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress.
Volume: 14
Issue: 1
Pages: 1333
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9133444 | J:40064
First Author: Rajan JV
Year: 1997
Journal: Dev Biol
Title: Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.
Volume: 184
Issue: 2
Pages: 385-401
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9196008 | J:41357
First Author: McAllister KA
Year: 1997
Journal: Mamm Genome
Title: Genetic mapping of the Brca2 breast cancer susceptibility gene on mouse chromosome 5.
Volume: 8
Issue: 7
Pages: 540-1
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22617326 | J:189304
First Author: Szabova L
Year: 2012
Journal: Cancer Res
Title: Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer.
Volume: 72
Issue: 16
Pages: 4141-53
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26920070 | J:235809
First Author: Thirthagiri E
Year: 2016
Journal: Hum Mol Genet
Title: BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.
Volume: 25
Issue: 10
Pages: 1934-1945
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9126738 | J:39764
First Author: Sharan SK
Year: 1997
Journal: Nature
Title: Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2.
Volume: 386
Issue: 6627
Pages: 804-10
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28394342 | J:240998
First Author: Huhn SC
Year: 2017
Journal: Oncogene
Title: Regulation of spindle integrity and mitotic fidelity by BCCIP.
Volume: 36
Issue: 33
Pages: 4750-4766
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21404276 | J:171231
First Author: Bouwman P
Year: 2011
Journal: J Pathol
Title: Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.
Volume: 224
Issue: 1
Pages: 10-21
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30704900 | J:274082
First Author: Zong D
Year: 2019
Journal: Mol Cell
Title: BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Volume: 73
Issue: 6
Pages: 1267-1281.e7
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23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
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35404932 | J:323634
First Author: Huo Y
Year: 2022
Journal: PLoS Genet
Title: Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration.
Volume: 18
Issue: 4
Pages: e1010138
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20484223 | J:161528
First Author: Rantakari P
Year: 2010
Journal: Hum Mol Genet
Title: Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.
Volume: 19
Issue: 15
Pages: 3021-9
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9537225 | J:46812
First Author: Friedman LS
Year: 1998
Journal: Cancer Res
Title: Thymic lymphomas in mice with a truncating mutation in Brca2.
Volume: 58
Issue: 7
Pages: 1338-43
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11832208 | J:76921
First Author: Venkitaraman AR
Year: 2002
Journal: Cell
Title: Cancer susceptibility and the functions of BRCA1 and BRCA2.
Volume: 108
Issue: 2
Pages: 171-82
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15375219 | J:93261
First Author: Daniels MJ
Year: 2004
Journal: Science
Title: Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2.
Volume: 306
Issue: 5697
Pages: 876-9
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Publication
37626143 | J:339675
First Author: Najafabadi MG
Year: 2023
Journal: Nat Commun
Title: A transcriptional response to replication stress selectively expands a subset of Brca2-mutant mammary epithelial cells.
Volume: 14
Issue: 1
Pages: 5206
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Publication
27037238 | J:232116
First Author: Michl J
Year: 2016
Journal: EMBO J
Title: Interplay between Fanconi anemia and homologous recombination pathways in genome integrity.
Volume: 35
Issue: 9
Pages: 909-23
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