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Search results 1401 to 1457 out of 1457 for Ins1

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0.029s

Type

Details

Score

Allele

Tg(Ins1-luc)77Park | MGI:4417828

Name:	transgene insertion 77, Soo-Young Park
Allele Type:	Transgenic
Attribute String:	Inserted expressed sequence

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Publication

16108006 | J:155851

First Author:	Park SY
Year:	2005
Journal:	Genesis
Title:	Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene.
Volume:	43
Issue:	2
Pages:	80-6

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Publication

23762423 | J:204244

First Author:	Yin H
Year:	2013
Journal:	PLoS One
Title:	Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.
Volume:	8
Issue:	6
Pages:	e65777

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Publication

18949679 | J:155847

First Author:	Park SY
Year:	2009
Journal:	Horm Metab Res
Title:	Noninvasive monitoring of changes in pancreatic beta-cell mass by bioluminescent imaging in MIP-luc transgenic mice.
Volume:	41
Issue:	1
Pages:	1-4

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Allele

Tg(Ins1-rtTA)#Caoy | MGI:6790391

Name:	transgene insertion, Yanan Cao
Allele Type:	Transgenic
Attribute String:	Transactivator

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Publication

24770644 | J:208032

First Author:	Hasegawa Y
Year:	2014
Journal:	Exp Anim
Title:	Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.
Volume:	63
Issue:	2
Pages:	183-91

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Strain

MGI:7339119 | C57BL/6J-Rr266<em1Hino> Rr268<em1Hino>

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Publication

9575186 | J:47674

First Author:	Pelegrin M
Year:	1998
Journal:	J Biol Chem
Title:	Evidence from transgenic mice that interferon-beta may be involved in the onset of diabetes mellitus.
Volume:	273
Issue:	20
Pages:	12332-40

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Publication

23099863 | J:208607

First Author:	Anguela XM
Year:	2013
Journal:	Diabetes
Title:	Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice.
Volume:	62
Issue:	2
Pages:	551-60

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Allele

Tg(Ins1-cre,-DsRed*T3)#Caoy | MGI:6790389

Name:	transgene insertion, Yanan Cao
Allele Type:	Transgenic
Attribute String:	Recombinase, Reporter

•

Allele

Tg(Ins1-cre)25Utr | MGI:5560759

Name:	transgene insertion 25, Ken-ichi Yagami
Allele Type:	Transgenic
Attribute String:	Recombinase

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Genotype

Symbol:	Rr266/Rr266 Rr268/Rr268
Background:	C57BL/6J-Rr266 Rr268
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

17130467 | J:121004

First Author:	Casellas A
Year:	2006
Journal:	Diabetes
Title:	Expression of IGF-I in pancreatic islets prevents lymphocytic infiltration and protects mice from type 1 diabetes.
Volume:	55
Issue:	12
Pages:	3246-55

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Publication

15557158 | J:94366

First Author:	Alba A
Year:	2004
Journal:	J Immunol
Title:	IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.
Volume:	173
Issue:	11
Pages:	6667-75

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Publication

25497096 | J:222657

First Author:	Piccand J
Year:	2014
Journal:	Cell Rep
Title:	Rfx6 maintains the functional identity of adult pancreatic β cells.
Volume:	9
Issue:	6
Pages:	2219-32

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Publication

25198535 | J:221524

First Author:	Patel M
Year:	2014
Journal:	PLoS One
Title:	Non-invasive bioluminescence imaging of β-cell function in obese-hyperglycemic [ob/ob] mice.
Volume:	9
Issue:	9
Pages:	e106693

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Publication

- | J:199064

First Author:	Pavlovic G
Year:	2013
Journal:	MGI Direct Data Submission
Title:	Data submissions from the Mouse Clinical Institute (ICS)

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Strain

MGI:6145639 | C57BL/6N-Tg(Ins1-cre)25Utr/Rbrc

Attribute String:

mutant strain, coisogenic, transgenic

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Publication

19380737 | J:148327

First Author:	Zhang SS
Year:	2009
Journal:	Proc Natl Acad Sci U S A
Title:	Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells.
Volume:	106
Issue:	18
Pages:	7531-6

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Publication

19656489 | J:151308

First Author:	Gauthier BR
Year:	2009
Journal:	Cell Metab
Title:	PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.
Volume:	10
Issue:	2
Pages:	110-8

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Publication

19560418 | J:150410

First Author:	Dougherty MK
Year:	2009
Journal:	Mol Cell
Title:	KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals.
Volume:	34
Issue:	6
Pages:	652-62

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Publication

20374962 | J:159614

First Author:	Gu C
Year:	2010
Journal:	Cell Metab
Title:	Pancreatic beta cells require NeuroD to achieve and maintain functional maturity.
Volume:	11
Issue:	4
Pages:	298-310

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Publication

24583012 | J:208142

First Author:	Kuang J
Year:	2014
Journal:	FEBS Lett
Title:	Identification of insulin as a novel retinoic acid receptor-related orphan receptor α target gene.
Volume:	588
Issue:	6
Pages:	1071-9

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Publication

37557182 | J:338980

First Author:	Sekiya M
Year:	2023
Journal:	Cell Rep
Title:	Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function.


Pages:	112914

•

Allele

Tg(Ins1-itTA)#Fto | MGI:5810641

Name:	transgene insertion, Francois Tronche
Allele Type:	Transgenic
Attribute String:	Transactivator

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Publication

29605295 | J:270542

First Author:	Matsuzawa T
Year:	2018
Journal:	Biochem Biophys Res Commun
Title:	Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion.
Volume:	499
Issue:	3
Pages:	688-695

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Genotype

Symbol:	Tg(Ins1-cre,-DsRed*T3)#Caoy/?
Background:	involves: C57BL/6J
Zygosity:	ot
Has Mutant Allele:	true

•

Publication

22628617 | J:186560

First Author:	Wang CY
Year:	2012
Journal:	J Lipid Res
Title:	Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.
Volume:	53
Issue:	8
Pages:	1493-501

•

Publication

26647386 | J:252954

First Author:	Zhu S
Year:	2016
Journal:	Diabetes
Title:	Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo.
Volume:	65
Issue:	3
Pages:	699-709

•

Publication

17620420 | J:126569

First Author:	Jarchum I
Year:	2007
Journal:	Diabetes
Title:	In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.
Volume:	56
Issue:	10
Pages:	2551-60

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Publication

21346176 | J:171756

First Author:	Niens M
Year:	2011
Journal:	Diabetes
Title:	Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach.
Volume:	60
Issue:	4
Pages:	1229-36

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Publication

27329800 | J:241413

First Author:	Mehta ZB
Year:	2016
Journal:	Am J Physiol Endocrinol Metab
Title:	Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.
Volume:	311
Issue:	2
Pages:	E488-507

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Publication

25355422 | J:219225

First Author:	Mitchell RK
Year:	2015
Journal:	Hum Mol Genet
Title:	Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Volume:	24
Issue:	5
Pages:	1390-9

•

Publication

19358156 | J:149908

First Author:	Scott GJ
Year:	2009
Journal:	Genesis
Title:	Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling.
Volume:	47
Issue:	6
Pages:	385-91

•

Publication

22566534 | J:203172

First Author:	Okamoto K
Year:	2012
Journal:	Diabetes
Title:	Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes.
Volume:	61
Issue:	7
Pages:	1734-41

•

Publication

19880509 | J:158307

First Author:	Hodish I
Year:	2010
Journal:	J Biol Chem
Title:	Misfolded proinsulin affects bystander proinsulin in neonatal diabetes.
Volume:	285
Issue:	1
Pages:	685-94

•

Publication

20858756 | J:172332

First Author:	Geng X
Year:	2011
Journal:	Am J Physiol Endocrinol Metab
Title:	α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion.
Volume:	300
Issue:	2
Pages:	E276-86

•

Publication

19264802 | J:173035

First Author:	Yang Y
Year:	2009
Journal:	Nucleic Acids Res
Title:	The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription.
Volume:	37
Issue:	8
Pages:	2529-38

•

Publication

20501672 | J:162929

First Author:	Chen TS
Year:	2010
Journal:	Endocrinology
Title:	Delineating biological pathways unique to embryonic stem cell-derived insulin-producing cell lines from their noninsulin-producing progenitor cell lines.
Volume:	151
Issue:	8
Pages:	3600-10

•

Publication

32003437 | J:286252

First Author:	Cerqueira FM
Year:	2020
Journal:	Biochem J
Title:	MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy.
Volume:	477
Issue:	2
Pages:	461-475

•

Publication

33784258 | J:312144

First Author:	Mishra A
Year:	2021
Journal:	JCI Insight
Title:	Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria.
Volume:	6
Issue:	9

•

Publication

26824049 | J:339768

First Author:	Babad J
Year:	2016
Journal:	J Diabetes Res
Title:	An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients.
Volume:	2016

Pages:	7959060

•

Strain

MGI:5574336 | B6.Cg-Gt(ROSA)26Sor<tm1Sor> Tg(Ins1-cre)25Utr

Attribute String:

congenic, targeted mutation, transgenic

•

Strain

MGI:5574340 | C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-EGFP,-tDsRed)Utr> Tg(Ins1-cre)25Utr

Attribute String:

transgenic, targeted mutation, coisogenic

•

Strain

MGI:5810645 | B6.Cg-Tg(Ins1-itTA)#Fto/Orl

Attribute String:

congenic, mutant strain, transgenic

•

Publication

37625131 | J:343219

First Author:	Ueki K
Year:	2023
Journal:	Diabetes
Title:	Establishment of Pancreatic β-Cell-Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery.
Volume:	72
Issue:	11
Pages:	1609-1620

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ins1-cre)25Utr/?
Background:	B6.Cg-Gt(ROSA)26Sor Tg(Ins1-cre)25Utr
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ins1-cre)25Utr/?
Background:	C57BL/6N-Gt(ROSA)26Sor Tg(Ins1-cre)25Utr
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ins1-cre,-DsRed*T3)#Caoy/?
Background:	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

21998599 | J:178002

First Author:	Bhatnagar S
Year:	2011
Journal:	PLoS Genet
Title:	Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.
Volume:	7
Issue:	10
Pages:	e1002323

•

Publication

18477811 | J:141688

First Author:	Goldsworthy M
Year:	2008
Journal:	Diabetes
Title:	Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.
Volume:	57
Issue:	8
Pages:	2234-44

•

Publication

26910463 | J:232925

First Author:	Rui J
Year:	2016
Journal:	Diabetologia
Title:	Methylation of insulin DNA in response to proinflammatory cytokines during the progression of autoimmune diabetes in NOD mice.
Volume:	59
Issue:	5
Pages:	1021-9

•

Publication

24172193 | J:205139

First Author:	Hasegawa Y
Year:	2013
Journal:	Exp Anim
Title:	Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination.
Volume:	62
Issue:	4
Pages:	295-304

•

Publication

- | J:23000

First Author:	MGD Nomenclature Committee
Year:	1995

Title:	Nomenclature Committee Use

•

Publication

28228267 | J:250943

First Author:	Yagishita Y
Year:	2017
Journal:	Cell Rep
Title:	Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.
Volume:	18
Issue:	8
Pages:	2030-2044

•

Publication

22363422 | J:223993

First Author:	Blondeau B
Year:	2012
Journal:	PLoS One
Title:	Novel transgenic mice for inducible gene overexpression in pancreatic cells define glucocorticoid receptor-mediated regulations of beta cells.
Volume:	7
Issue:	2
Pages:	e30210

•

Publication

- | J:28563

First Author:	Beechey CV
Year:	1995
Journal:	Mouse Genome
Title:	Genetic imprinting map
Volume:	93
Issue:	1
Pages:	89-92

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