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Search results 601 to 669 out of 669 for Pbx1

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Type Details Score
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Protein
P41778
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
P41778-2
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Publication
12505987 | -
First Author: Kilstrup-Nielsen C
Year: 2003
Journal: EMBO J
Title: PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain.
Volume: 22
Issue: 1
Pages: 89-99
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Gene
6651 | SON
Type: gene
Organism: human
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Interaction Experiment
Bailey JS (2004)
Description: Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1.
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Allele
Pbx1<em1Dunw> | MGI:6883575
Name: pre B cell leukemia homeobox 1; endonuclease-mediated mutation 1, Sally L Dunwoodie
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Publication
12529389 | -
First Author: Chao SH
Year: 2003
Journal: Mol Cell Biol
Title: Identification of homeodomain proteins, PBX1 and PREP1, involved in the transcription of murine leukemia virus.
Volume: 23
Issue: 3
Pages: 831-41
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Publication
27354364 | -
First Author: Villaescusa JC
Year: 2016
Journal: EMBO J
Title: A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.
Volume: 35
Issue: 18
Pages: 1963-78
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Publication
15684392 | -
First Author: Berry FB
Year: 2005
Journal: Mol Cell Biol
Title: FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner.
Volume: 25
Issue: 4
Pages: 1415-24
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Genotype
Genotype
Symbol: Pbx1/Pbx1
Background: C57BL/6J-Pbx1
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0112359 | congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay
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HT Experiment
E-GEOD-82099 | RNA-Seq of mouse E12.5 brain regions
Series Id: GSE82099
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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DO Term
DOID:0080649 | B-lymphoblastic leukemia/lymphoma with TCF3-PBX1
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Publication
7791786 | -
First Author: Lu Q
Year: 1995
Journal: Mol Cell Biol
Title: Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
Volume: 15
Issue: 7
Pages: 3786-95
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HT Experiment
GSE106399 | Lung transcriptome analysis of mice with lung mesechyme specific deletion of Pbx transcription factors
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-GEOD-39605 | TALE transcription factors binding and transcriptional effect [RNA-Seq]
Series Id: GSE39605
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
Q8BFR8
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Protein
D6RCU6
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
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Protein
G3UXL9
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
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Protein
B2FDH3
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
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Protein
D3Z318
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
D6RGB0
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein
H3BLL9
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
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Protein
D6RIQ9
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
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Protein
H3BK27
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
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Protein
B2FDH2
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: true
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Publication
1363814 | -
First Author: Bürglin TR
Year: 1992
Journal: Nat Genet
Title: New motif in PBX genes.
Volume: 1
Issue: 5
Pages: 319-20
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Publication
30396330 | -
First Author: Joo S
Year: 2018
Journal: BMC Biol
Title: Common ancestry of heterodimerizing TALE homeobox transcription factors across Metazoa and Archaeplastida.
Volume: 16
Issue: 1
Pages: 136
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Protein Domain
IPR005542 | PBX_PBC_dom
Type: Domain
Description: Pbx proteins are members of the TALE (three-amino-acid loop extension) family of atypical homeodomain proteins, whose membersare characterised by a three-residue insertion between helix 1 and 2 and plays essential roles during embryonic development by participating in interactive TF networks. The heterodimerization of TALE proteins serves as a trigger for precise execution of developmental programs. Examinationof Pbx1 has shown that, in addition to the homeodomain, a short 16-residue C-terminal tail is essential for maximal cooperative interactions withHox partners as well as for maximal monomeric binding of Pbx1 to DNA. The PCB domain is a bipartite acidic domain that can be further subdivided into an A and B region [, , ].
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HT Experiment
GSE197858 | A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2 [single-cell RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
9336443 | J:44253
First Author: Bürglin TR
Year: 1997
Journal: Nucleic Acids Res
Title: Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals.
Volume: 25
Issue: 21
Pages: 4173-80
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Publication
17665086 | -
First Author: Mukherjee K
Year: 2007
Journal: J Mol Evol
Title: Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution.
Volume: 65
Issue: 2
Pages: 137-53
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Protein Domain
IPR038043 | SMARCD3
Type: Family
Description: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (SMARCD3 or BAF60C) is a component of several complexes that remodel chromatin, a mechanism by which selected genes are transcriptionally activated or repressed. The complexes are SWI/SNF, which changes chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner []; BAF []; and the npBAF and nBAF, which are neuron-specific []. SMARCD3 is known to interact with a number of proteins, including SMARCA4/BRG1/BAF190A []and the homeobox protein PBX1 [].
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Publication
16219351 | J:106749
First Author: Hao X
Year: 2006
Journal: Leuk Res
Title: Histologic and molecular characterizations of megakaryocytic leukemia in mice.
Volume: 30
Issue: 4
Pages: 397-406
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HT Experiment
E-MTAB-9785 | Single-cell RNA-seq of tailbuds from control, Pbx1/Pbx2 compound and Pbx1/Pbx2 double-knockout E8.5/E9.0 embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
14701856 | J:89493
First Author: Debril MB
Year: 2004
Journal: J Biol Chem
Title: Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.
Volume: 279
Issue: 16
Pages: 16677-86
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Publication
21059917 | J:166594
First Author: Liu J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1.
Volume: 107
Issue: 47
Pages: 20494-9
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Publication
10337615 | J:54500
First Author: Li Y
Year: 1999
Journal: Mamm Genome
Title: Sequence and genomic organization of the mouse Lim1 gene.
Volume: 10
Issue: 5
Pages: 444-6
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Publication
19346496 | J:148893
First Author: Horman SR
Year: 2009
Journal: Blood
Title: Gfi1 integrates progenitor versus granulocytic transcriptional programming.
Volume: 113
Issue: 22
Pages: 5466-75
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Publication
24903482 | J:217841
First Author: Fukuda S
Year: 2015
Journal: Leukemia
Title: Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1.
Volume: 29
Issue: 2
Pages: 433-40
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Publication
17676642 | J:124185
First Author: Matis C
Year: 2007
Journal: Dev Dyn
Title: Identification of Lmo1 as part of a Hox-dependent regulatory network for hindbrain patterning.
Volume: 236
Issue: 9
Pages: 2675-84
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Publication
16469876 | J:135648
First Author: Mamo A
Year: 2006
Journal: Blood
Title: Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation.
Volume: 108
Issue: 2
Pages: 622-9
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Publication
37163604 | J:335557
First Author: Olatoke T
Year: 2023
Journal: Sci Adv
Title: Single-cell multiomic analysis identifies a HOX-PBX gene network regulating the survival of lymphangioleiomyomatosis cells.
Volume: 9
Issue: 19
Pages: eadf8549
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Publication
8804307 | J:35263
First Author: Wang W
Year: 1996
Journal: Genes Dev
Title: Diversity and specialization of mammalian SWI/SNF complexes.
Volume: 10
Issue: 17
Pages: 2117-30
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Protein
Q99NE9
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Publication
9032278 | J:44165
First Author: Fu X
Year: 1997
Journal: Mol Cell Biol
Title: E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts.
Volume: 17
Issue: 3
Pages: 1503-12
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Publication
20864515 | J:170202
First Author: Oriente F
Year: 2011
Journal: Diabetes
Title: Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase.
Volume: 60
Issue: 1
Pages: 138-47
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Publication
18644868 | J:140357
First Author: Oriente F
Year: 2008
Journal: Mol Cell Biol
Title: Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.
Volume: 28
Issue: 18
Pages: 5634-45
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Publication
29991556 | J:266048
First Author: Shepherd MS
Year: 2018
Journal: Blood
Title: Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.
Volume: 132
Issue: 8
Pages: 791-803
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Publication
33414485 | J:308564
First Author: Dutta A
Year: 2021
Journal: Leukemia
Title: U2af1 is required for survival and function of hematopoietic stem/progenitor cells.
Volume: 35
Issue: 8
Pages: 2382-2398
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Publication
27590741 | J:236857
First Author: Jung JG
Year: 2016
Journal: Cancer Res
Title: Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1.
Volume: 76
Issue: 21
Pages: 6351-6361
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Publication
11278854 | J:69873
First Author: Di Rocco G
Year: 2001
Journal: J Biol Chem
Title: The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function.
Volume: 276
Issue: 23
Pages: 20506-15
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Publication
16434237 | J:111160
First Author: Di Giacomo G
Year: 2006
Journal: Gene Expr Patterns
Title: Spatio-temporal expression of Pbx3 during mouse organogenesis.
Volume: 6
Issue: 7
Pages: 747-57
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Publication
25157139 | J:216398
First Author: Risolino M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
Volume: 111
Issue: 36
Pages: E3775-84
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Publication
18765789 | J:138780
First Author: Lange M
Year: 2008
Journal: Genes Dev
Title: Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Volume: 22
Issue: 17
Pages: 2370-84
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Protein
O35984
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
O35317
Organism: Mus musculus/domesticus
Length: 434  
Fragment?: false
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Protein
V9GXB8
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein
Q3TWM8
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q71VB4
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Protein
Q5PPM1
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q3UYU9
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q4FJL3
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q3UR63
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Publication
17640523 | J:132090
First Author: Lessard J
Year: 2007
Journal: Neuron
Title: An essential switch in subunit composition of a chromatin remodeling complex during neural development.
Volume: 55
Issue: 2
Pages: 201-15
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Protein
Q6P9Z1
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: false
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Protein
A0A0G2JG60
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom