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Search results 1 to 100 out of 104 for Gch1

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Category: Publication
Type Details Score
Publication
First Author: McNeill E
Year: 2018
Journal: Nat Commun
Title: Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin.
Volume: 9
Issue: 1
Pages: 5409
Publication
First Author: Douglas G
Year: 2015
Journal: Dev Biol
Title: A requirement for Gch1 and tetrahydrobiopterin in embryonic development.
Volume: 399
Issue: 1
Pages: 129-38
Publication
First Author: Douglas G
Year: 2018
Journal: Cardiovasc Res
Title: Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Volume: 114
Issue: 10
Pages: 1385-1399
Publication  
First Author: McNeill E
Year: 2015
Journal: Free Radic Biol Med
Title: Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.
Volume: 79
Pages: 206-16
Publication
First Author: Adlam D
Year: 2012
Journal: Cardiovasc Res
Title: Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
Volume: 93
Issue: 4
Pages: 694-701
Publication
First Author: Zschiebsch K
Year: 2019
Journal: J Cell Mol Med
Title: Mast cell tetrahydrobiopterin contributes to itch in mice.
Volume: 23
Issue: 2
Pages: 985-1000
Publication
First Author: Shimoji M
Year: 1999
Journal: J Neurochem
Title: GTP cyclohydrolase I gene expression in the brains of male and female hph-1 mice.
Volume: 72
Issue: 2
Pages: 757-64
Publication
First Author: Canevari L
Year: 1999
Journal: J Neurochem
Title: Stimulation of the brain NO/cyclic GMP pathway by peripheral administration of tetrahydrobiopterin in the hph-1 mouse.
Volume: 73
Issue: 6
Pages: 2563-8
Publication
First Author: Nandi M
Year: 2005
Journal: Circulation
Title: Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse.
Volume: 111
Issue: 16
Pages: 2086-90
Publication
First Author: Montañez CS
Year: 1999
Journal: Mol Genet Metab
Title: Linkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural gene.
Volume: 68
Issue: 1
Pages: 91-2
Publication
First Author: Gütlich M
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Molecular characterization of HPH-1: a mouse mutant deficient in GTP cyclohydrolase I activity.
Volume: 203
Issue: 3
Pages: 1675-81
Publication
First Author: Tatham AL
Year: 2009
Journal: J Biol Chem
Title: GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
Volume: 284
Issue: 20
Pages: 13660-8
Publication
First Author: Khoo JP
Year: 2004
Journal: Mol Genet Metab
Title: Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse.
Volume: 82
Issue: 3
Pages: 251-4
Publication
First Author: Cronin SJF
Year: 2018
Journal: Nature
Title: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Volume: 563
Issue: 7732
Pages: 564-568
Publication
First Author: d'Uscio LV
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.
Volume: 301
Issue: 6
Pages: H2227-34
Publication
First Author: Xie HH
Year: 2010
Journal: Hypertension
Title: GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.
Volume: 56
Issue: 6
Pages: 1137-44
Publication
First Author: Chuaiphichai S
Year: 2014
Journal: Hypertension
Title: Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Volume: 64
Issue: 3
Pages: 530-40
Publication
First Author: Chuaiphichai S
Year: 2023
Journal: Am J Physiol Heart Circ Physiol
Title: Endothelial cell-specific roles for tetrahydrobiopterin in myocardial function, cardiac hypertrophy, and response to myocardial ischemia-reperfusion injury.
Volume: 324
Issue: 4
Pages: H430-H442
Publication  
First Author: Wu HE
Year: 2016
Journal: Sci Rep
Title: Cardiomyocyte GTP Cyclohydrolase 1 Protects the Heart Against Diabetic Cardiomyopathy.
Volume: 6
Pages: 27925
Publication
First Author: Carnicer R
Year: 2012
Journal: Circ Res
Title: Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.
Volume: 111
Issue: 6
Pages: 718-27
Publication
First Author: Peterson TE
Year: 2009
Journal: Hypertension
Title: Guanosine triphosphate cyclohydrolase I expression and enzymatic activity are present in caveolae of endothelial cells.
Volume: 53
Issue: 2
Pages: 189-95
Publication
First Author: Latremoliere A
Year: 2015
Journal: Neuron
Title: Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Volume: 86
Issue: 6
Pages: 1393-406
Publication
First Author: Nomura T
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase I.
Volume: 191
Issue: 2
Pages: 523-7
Publication  
First Author: Jiang X
Year: 2019
Journal: Metabolism
Title: A novel GTPCH deficiency mouse model exhibiting tetrahydrobiopterin-related metabolic disturbance and infancy-onset motor impairments.
Volume: 94
Pages: 96-104
Publication  
First Author: Ichinose H
Year: 2013
Journal: Adv Pharmacol
Title: GTP cyclohydrolase regulation: implications for brain development and function.
Volume: 68
Pages: 23-35
Publication
First Author: Pelletier I
Year: 2001
Journal: Mech Dev
Title: Cloning and developmental expression of zebrafish GTP cyclohydrolase I.
Volume: 109
Issue: 1
Pages: 99-103
Publication
First Author: Ichinose H
Year: 1994
Journal: Nat Genet
Title: Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene.
Volume: 8
Issue: 3
Pages: 236-42
Publication
First Author: Ichinose H
Year: 1995
Journal: J Biol Chem
Title: Characterization of mouse and human GTP cyclohydrolase I genes. Mutations in patients with GTP cyclohydrolase I deficiency.
Volume: 270
Issue: 17
Pages: 10062-71
Publication
First Author: Tie L
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.
Volume: 296
Issue: 6
Pages: E1423-9
Publication
First Author: Belik J
Year: 2011
Journal: Free Radic Biol Med
Title: Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse.
Volume: 51
Issue: 12
Pages: 2227-33
Publication
First Author: Tie L
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1.
Volume: 306
Issue: 10
Pages: E1120-31
Publication  
First Author: Santhanam AV
Year: 2015
Journal: Brain Res
Title: Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.
Volume: 1625
Pages: 198-205
Publication
First Author: Christensen R
Year: 2005
Journal: Exp Dermatol
Title: Characterization of transgenic mice with the expression of phenylalanine hydroxylase and GTP cyclohydrolase I in the skin.
Volume: 14
Issue: 7
Pages: 535-42
Publication
First Author: Bailey JD
Year: 2019
Journal: Cell Rep
Title: Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
Volume: 28
Issue: 1
Pages: 218-230.e7
Publication
First Author: Gil M
Year: 2007
Journal: J Neurochem
Title: Regulation of GTP cyclohydrolase I expression by orphan receptor Nurr1 in cell culture and in vivo.
Volume: 101
Issue: 1
Pages: 142-50
Publication
First Author: Du YH
Year: 2008
Journal: Circulation
Title: Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
Volume: 117
Issue: 8
Pages: 1045-54
Publication  
First Author: Thöny B
Year: 2000
Journal: Biochem J
Title: Tetrahydrobiopterin biosynthesis, regeneration and functions.
Volume: 347 Pt 1
Pages: 1-16
Publication
First Author: Wyler SC
Year: 2015
Journal: ACS Chem Neurosci
Title: Pet-1 Controls Tetrahydrobiopterin Pathway and Slc22a3 Transporter Genes in Serotonin Neurons.
Volume: 6
Issue: 7
Pages: 1198-205
Publication
First Author: Liu C
Year: 2010
Journal: Nat Neurosci
Title: Pet-1 is required across different stages of life to regulate serotonergic function.
Volume: 13
Issue: 10
Pages: 1190-8
Publication
First Author: Hwang DY
Year: 2009
Journal: J Neurochem
Title: Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons.
Volume: 111
Issue: 5
Pages: 1202-12
Publication
First Author: Scavuzzo MA
Year: 2018
Journal: Nat Commun
Title: Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.
Volume: 9
Issue: 1
Pages: 3356
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication
First Author: McDonald JD
Year: 1988
Journal: J Neurochem
Title: Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity.
Volume: 50
Issue: 2
Pages: 655-7
Publication  
First Author: Belik J
Year: 2017
Journal: Sci Rep
Title: Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice.
Volume: 7
Pages: 39854
Publication
First Author: Brand MP
Year: 1996
Journal: Brain Res
Title: Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse.
Volume: 735
Issue: 1
Pages: 169-72
Publication
First Author: Welsh C
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Tetrahydrobiopterin deficiency induces gastroparesis in newborn mice.
Volume: 305
Issue: 1
Pages: G47-57
Publication
First Author: Gunasekera RS
Year: 2009
Journal: Mol Genet Metab
Title: In vivo regulation of phenylalanine hydroxylase in the genetic mutant hph-1 mouse model.
Volume: 98
Issue: 3
Pages: 264-72
Publication
First Author: Wang CH
Year: 2005
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury.
Volume: 289
Issue: 2
Pages: R299-304
Publication
First Author: Abel RM
Year: 2004
Journal: Anat Histol Embryol
Title: A histological study of the hph-1 mouse mutant: an animal model of phenylketonuria and infantile hypertrophic pyloric stenosis.
Volume: 33
Issue: 3
Pages: 125-30
Publication  
First Author: Santhanam AV
Year: 2012
Journal: Brain Res
Title: PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice.
Volume: 1483
Pages: 89-95
Publication
First Author: Crabtree MJ
Year: 2011
Journal: Free Radic Biol Med
Title: Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
Volume: 50
Issue: 11
Pages: 1639-46
Publication
First Author: Bode VC
Year: 1988
Journal: Genetics
Title: hph-1: a mouse mutant with hereditary hyperphenylalaninemia induced by ethylnitrosourea mutagenesis.
Volume: 118
Issue: 2
Pages: 299-305
Publication
First Author: Rivera JC
Year: 2017
Journal: J Neuroinflammation
Title: Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina.
Volume: 14
Issue: 1
Pages: 181
Publication
First Author: Brand MP
Year: 1995
Journal: J Inherit Metab Dis
Title: Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse.
Volume: 18
Issue: 1
Pages: 33-9
Publication
First Author: Edgar KS
Year: 2023
Journal: Sci Rep
Title: BH4 supplementation reduces retinal cell death in ischaemic retinopathy.
Volume: 13
Issue: 1
Pages: 21292
Publication
First Author: Khoo JP
Year: 2005
Journal: Circulation
Title: Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.
Volume: 111
Issue: 16
Pages: 2126-33
Publication
First Author: Santhanam AV
Year: 2012
Journal: J Neurochem
Title: Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.
Volume: 122
Issue: 6
Pages: 1211-8
Publication
First Author: Gao L
Year: 2012
Journal: Hypertension
Title: Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid.
Volume: 59
Issue: 1
Pages: 158-66
Publication  
First Author: Maeda T
Year: 2000
Journal: Brain Dev
Title: Studies on the genotype-phenotype relation in the hph-1 mouse mutant deficient in guanosine triphosphate (GTP) cyclohydrolase I activity.
Volume: 22 Suppl 1
Pages: S50-3
Publication
First Author: Brand MP
Year: 1996
Journal: J Neurochem
Title: Neurochemical effects following peripheral administration of tetrahydropterin derivatives to the hph-1 mouse.
Volume: 66
Issue: 3
Pages: 1150-6
Publication  
First Author: Nasser A
Year: 2014
Journal: Neurosci Res
Title: Anxiety- and depression-like phenotype of hph-1 mice deficient in tetrahydrobiopterin.
Volume: 89
Pages: 44-53
Publication
First Author: McDonald JD
Year: 1988
Journal: Pediatr Res
Title: Hyperphenylalaninemia in the hph-1 mouse mutant.
Volume: 23
Issue: 1
Pages: 63-7
Publication
First Author: Hyland K
Year: 1996
Journal: J Neurochem
Title: Tetrahydrobiopterin and biogenic amine metabolism in the hph-1 mouse.
Volume: 67
Issue: 2
Pages: 752-9
Publication  
First Author: Oguri Y
Year: 2017
Journal: JCI Insight
Title: Tetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism.
Volume: 2
Issue: 9
Publication
First Author: Xue J
Year: 2017
Journal: J Invest Dermatol
Title: The Nrf2/GCH1/BH4 Axis Ameliorates Radiation-Induced Skin Injury by Modulating the ROS Cascade.
Volume: 137
Issue: 10
Pages: 2059-2068
Publication
First Author: Li P
Year: 2016
Journal: Circulation
Title: Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in Vivo.
Volume: 134
Issue: 22
Pages: 1752-1765
Publication
First Author: Cronin SJF
Year: 2022
Journal: Sci Transl Med
Title: Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer.
Volume: 14
Issue: 660
Pages: eabj1531