Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2769723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2851823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2762123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2850023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2852723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2845723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1795023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2874723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1832123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2854023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6881 |
|
Specimen Label: |
GUDMAP:6881 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2760523 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2769723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2851823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2762123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2850023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2852723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2845723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1795023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1869223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1832123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2853323 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000679 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3152723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5541239 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6882 |
|
Specimen Label: |
GUDMAP:6882 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bottelbergs A |
Year: |
2010 |
Journal: |
Glia |
Title: |
Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes. |
Volume: |
58 |
Issue: |
13 |
Pages: |
1532-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shepard AR |
Year: |
2007 |
Journal: |
Hum Mol Genet |
Title: |
Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure. |
Volume: |
16 |
Issue: |
6 |
Pages: |
609-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baes M |
Year: |
1997 |
Journal: |
Nat Genet |
Title: |
A mouse model for Zellweger syndrome. |
Volume: |
17 |
Issue: |
1 |
Pages: |
49-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huyghe S |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
Peroxisomal multifunctional protein 2 is essential for lipid homeostasis in Sertoli cells and male fertility in mice. |
Volume: |
147 |
Issue: |
5 |
Pages: |
2228-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bottelbergs A |
Year: |
2012 |
Journal: |
J Neuroinflammation |
Title: |
Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system. |
Volume: |
9 |
|
Pages: |
61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dirkx R |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. |
Volume: |
357 |
Issue: |
3 |
Pages: |
718-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yakunin E |
Year: |
2010 |
Journal: |
J Neurosci Res |
Title: |
alpha-Synuclein abnormalities in mouse models of peroxisome biogenesis disorders. |
Volume: |
88 |
Issue: |
4 |
Pages: |
866-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Björkman J |
Year: |
2002 |
Journal: |
Genomics |
Title: |
Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: gene structure, tissue expression, and localization of the protein to peroxisomes. |
Volume: |
79 |
Issue: |
2 |
Pages: |
162-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huyghe S |
Year: |
2001 |
Journal: |
Biochem J |
Title: |
Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. |
Volume: |
353 |
Issue: |
Pt 3 |
Pages: |
673-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tchernev VT |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering. |
Volume: |
40 |
Issue: |
1 |
Pages: |
170-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bettenhausen B |
Year: |
1995 |
Journal: |
Genomics |
Title: |
Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. |
Volume: |
28 |
Issue: |
3 |
Pages: |
436-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Copeland NG |
Year: |
1999 |
Journal: |
Database Release |
Title: |
Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Papin J |
Year: |
2004 |
Journal: |
Curr Opin Biotechnol |
Title: |
Bioinformatics and cellular signaling. |
Volume: |
15 |
Issue: |
1 |
Pages: |
78-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
|
Title: |
Rat to Mouse ISO GO annotation transfer |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2000 |
|
Title: |
Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
|
Title: |
Human to Mouse ISO GO annotation transfer |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Gaudet P |
Year: |
2011 |
Journal: |
Brief Bioinform |
Title: |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. |
Volume: |
12 |
Issue: |
5 |
Pages: |
449-62 |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Miyata N |
Year: |
2012 |
Journal: |
Traffic |
Title: |
AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase. |
Volume: |
13 |
Issue: |
1 |
Pages: |
168-83 |
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Publication |
First Author: |
Ito R |
Year: |
2001 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Temperature-sensitive phenotype of Chinese hamster ovary cells defective in PEX5 gene. |
Volume: |
288 |
Issue: |
2 |
Pages: |
321-7 |
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Publication |
First Author: |
Ramón NM |
Year: |
2010 |
Journal: |
Mol Biol Cell |
Title: |
Interdependence of the peroxisome-targeting receptors in Arabidopsis thaliana: PEX7 facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes. |
Volume: |
21 |
Issue: |
7 |
Pages: |
1263-71 |
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DO Term |
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DO Term |
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GO Term |
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Publication |
First Author: |
Neufeld C |
Year: |
2009 |
Journal: |
EMBO J |
Title: |
Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19. |
Volume: |
28 |
Issue: |
6 |
Pages: |
745-54 |
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Publication |
First Author: |
Chang CC |
Year: |
1999 |
Journal: |
J Cell Biol |
Title: |
PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import. |
Volume: |
147 |
Issue: |
4 |
Pages: |
761-74 |
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DO Term |
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Publication |
First Author: |
Bankston JR |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels. |
Volume: |
109 |
Issue: |
20 |
Pages: |
7899-904 |
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Publication |
First Author: |
Han Y |
Year: |
2020 |
Journal: |
Channels (Austin) |
Title: |
The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels. |
Volume: |
14 |
Issue: |
1 |
Pages: |
110-122 |
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Protein Domain |
Type: |
Family |
Description: |
Peroxisomal proteins catalyse metabolic reactions. The import of proteins from the cytosol into the peroxisomes matrix depends on more than a dozen peroxin (PEX) proteins, among which PEX5 and PEX7 serve as receptors that shuttle proteins bearing one of two peroxisome-targeting signals (PTSs) into the organelle. PEX5 is the PTS1 receptor, while PEX7 is the PTS2 receptor. In plants, PEX7 depends on PEX5 binding to deliver PTS2 cargo into the peroxisome, and PEX7 also facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes [, ]. This entry include PEX5 (also known as PTS1R) from animals, fungi and plants. This entry also includes PEX5L from vertebrates. PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import [, , ]. Based on subcellular localization and binding properties mammalian PEX5 may function as a regulator in an early step of the PTS1 protein import process []. PEX5L acts as an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence [, ]. Interestingly, although PEX5 and PEX5L have structurally similar binding at their TPR domains, they bind to different substrates in vivo []. |
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Publication |
First Author: |
Ito R |
Year: |
2005 |
Journal: |
J Biochem |
Title: |
Identification of Pex5pM, and retarded maturation of 3-ketoacyl-CoA thiolase and acyl-CoA oxidase in CHO cells expressing mutant Pex5p isoforms. |
Volume: |
138 |
Issue: |
6 |
Pages: |
781-90 |
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Publication |
First Author: |
Otera H |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1639-55 |
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Publication |
First Author: |
Woodward AW |
Year: |
2005 |
Journal: |
Mol Biol Cell |
Title: |
The Arabidopsis peroxisomal targeting signal type 2 receptor PEX7 is necessary for peroxisome function and dependent on PEX5. |
Volume: |
16 |
Issue: |
2 |
Pages: |
573-83 |
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Publication |
First Author: |
Braverman N |
Year: |
1997 |
Journal: |
Nat Genet |
Title: |
Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata. |
Volume: |
15 |
Issue: |
4 |
Pages: |
369-76 |
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Publication |
First Author: |
van den Brink DM |
Year: |
2003 |
Journal: |
Am J Hum Genet |
Title: |
Identification of PEX7 as the second gene involved in Refsum disease. |
Volume: |
72 |
Issue: |
2 |
Pages: |
471-7 |
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Publication |
First Author: |
Marzioch M |
Year: |
1994 |
Journal: |
EMBO J |
Title: |
PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes. |
Volume: |
13 |
Issue: |
20 |
Pages: |
4908-18 |
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Protein Domain |
Type: |
Family |
Description: |
Peroxisomal proteins catalyse metabolic reactions. The import of proteins from the cytosol into the peroxisomes matrix depends on more than a dozen peroxin (PEX) proteins, among which PEX5 and PEX7 serve as receptors that shuttle proteins bearing one of two peroxisome-targeting signals (PTSs) into the organelle. PEX5 is the PTS1 receptor, while PEX7 is the PTS2 receptor. In plants, PEX7 depends on PEX5 binding to deliver PTS2 cargo into the peroxisome, and PEX7 also facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes [, ]. This entry represents PEX7 from animals, fungi and plants. In plants it plays important roles in embryonic development, seedling establishment, and vegetative growth []. Budding yeast PEX7 homologue, Pas7, is necessary for import of thiolase (a PTS2-containing protein) []. In humans PEX7 has been linked to several diseases, such as Rhizomelic chondrodysplasia punctata 1 (RCDP1) []and Peroxisome biogenesis disorder 9B (PBD9B) []. |
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Publication |
First Author: |
El Magraoui F |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor. |
Volume: |
9 |
Issue: |
8 |
Pages: |
e105894 |
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Publication |
First Author: |
Zolman BK |
Year: |
2005 |
Journal: |
Plant Cell |
Title: |
Identification and functional characterization of Arabidopsis PEROXIN4 and the interacting protein PEROXIN22. |
Volume: |
17 |
Issue: |
12 |
Pages: |
3422-35 |
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Protein Domain |
Type: |
Family |
Description: |
Peroxisomal proteins, called peroxins, participate in the process of peroxisome assembly. Specific amino acid sequences (PTS or peroxisomal targeting signal) at the C terminus (PTS1) or N terminus (PTS2) are present in peroxisomal matrix proteins, which signals them to be imported. The protein receptors Pex5 and Pex7 accompany their cargoes (containing a PTS1 or a PTS2 amino acid sequence, respectively) into the peroxisome. Ubiquitination appears to be crucial for the export of Pex5 from the peroxisome to the cytosol. The monoubiquitination of the PTS1-receptor Pex5p is catalyzed by the E2 enzyme Pex4.Pex22 anchors Pex4 to the peroxisome membrane [, ]. Moreover, Pex4 requires the interaction with Pex22 to display full activity []. The N-terminal portion of Pex22 has a membrane anchoring function, whereas the C-terminal domain harbours its biological activity. The soluble C-terminal domain of Pex22 is essential for peroxisomal biogenesis and efficient monoubiquitination of the import receptor Pex5 []. |
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Protein Domain |
Type: |
Family |
Description: |
This entry represents the PEX5-related proteins (PEX5L, also known as TRIP8b) from vertebrates. It acts as an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence [, ]. Interestingly, although PEX5L and PEX5 have structurally similar binding at their TPR domains, they bind to different substrates in vivo []. |
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Protein Domain |
Type: |
Family |
Description: |
Peroxisome biogenesis factor 1, also known as peroxin-1 or PEX1, is a component of the peroxisomal protein import machinery. In addition to its role in import, PEX1 together with PEX6, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor PEX5 from the peroxisomal membrane to the cytosol [, , ]. |
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Publication |
First Author: |
Birschmann I |
Year: |
2005 |
Journal: |
FEBS J |
Title: |
Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p. |
Volume: |
272 |
Issue: |
1 |
Pages: |
47-58 |
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Publication |
First Author: |
Platta HW |
Year: |
2005 |
Journal: |
Nat Cell Biol |
Title: |
Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol. |
Volume: |
7 |
Issue: |
8 |
Pages: |
817-22 |
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Publication |
First Author: |
Rosenkranz K |
Year: |
2006 |
Journal: |
FEBS J |
Title: |
Functional association of the AAA complex and the peroxisomal importomer. |
Volume: |
273 |
Issue: |
16 |
Pages: |
3804-15 |
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Publication |
First Author: |
Williams C |
Year: |
2006 |
Journal: |
Biochim Biophys Acta |
Title: |
Pex13p: docking or cargo handling protein? |
Volume: |
1763 |
Issue: |
12 |
Pages: |
1585-91 |
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Publication |
First Author: |
Stein K |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
Interactions of Pex7p and Pex18p/Pex21p with the peroxisomal docking machinery: implications for the first steps in PTS2 protein import. |
Volume: |
22 |
Issue: |
17 |
Pages: |
6056-69 |
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Protein Domain |
Type: |
Family |
Description: |
Peroxin-13 (Pex13), located in the peroxisomal membrane, is a component of the peroxisomal translocation machinery with peroxin-14 and peroxin-17. Both termini of peroxin-13 are oriented to the cytosol. It is required for peroxisomal association of peroxin-14 []. Both human and budding yeast Pex13 bind to the PTS1 signal recognition factor Pex5. However, they bind to Pex5 through different binding sites []. In budding yeasts, Pex13 is also involved in the PTS2 signal recognition through its interaction with Pex7 []. |
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Publication |
First Author: |
Koller A |
Year: |
1999 |
Journal: |
J Cell Biol |
Title: |
Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane. |
Volume: |
146 |
Issue: |
1 |
Pages: |
99-112 |
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Publication |
First Author: |
Williams C |
Year: |
2012 |
Journal: |
EMBO J |
Title: |
Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex. |
Volume: |
31 |
Issue: |
2 |
Pages: |
391-402 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
567
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
639
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Fragment?: |
false |
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