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Search results 101 to 200 out of 507 for Vhl

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Type Details Score
Publication
22084310 | J:178823
First Author: Kurihara T
Year: 2011
Journal: J Cell Biol
Title: Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye.
Volume: 195
Issue: 4
Pages: 689-701
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Publication
36064840 | J:328344
First Author: Liu R
Year: 2022
Journal: Nat Commun
Title: HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection.
Volume: 13
Issue: 1
Pages: 5093
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Publication
19065050 | J:144713
First Author: Cantley J
Year: 2009
Journal: J Clin Invest
Title: Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.
Volume: 119
Issue: 1
Pages: 125-35
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Publication
20817091 | J:280184
First Author: Lange C
Year: 2011
Journal: Neurobiol Dis
Title: Retina-specific activation of a sustained hypoxia-like response leads to severe retinal degeneration and loss of vision.
Volume: 41
Issue: 1
Pages: 119-30
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Publication
17203215 | J:123030
First Author: Park SK
Year: 2007
Journal: Int J Oncol
Title: von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling expression of glucose transporter 2 and glucose 6-phosphatase.
Volume: 30
Issue: 2
Pages: 341-8
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Publication
23744542 | J:200011
First Author: Mans DA
Year: 2013
Journal: J Pathol
Title: Regulation of E2F1 by the von Hippel-Lindau tumour suppressor protein predicts survival in renal cell cancer patients.
Volume: 231
Issue: 1
Pages: 117-29
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Publication
18667485 | J:153791
First Author: Kimura K
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.
Volume: 295
Issue: 4
Pages: F1023-9
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Publication
18474617 | J:137442
First Author: Frew IJ
Year: 2008
Journal: Mol Cell Biol
Title: Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia.
Volume: 28
Issue: 14
Pages: 4536-48
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Publication
15128677 | J:91056
First Author: Pfander D
Year: 2004
Journal: Development
Title: Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.
Volume: 131
Issue: 10
Pages: 2497-508
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Publication
17549257 | J:122021
First Author: Wang Y
Year: 2007
Journal: J Clin Invest
Title: The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
Volume: 117
Issue: 6
Pages: 1616-26
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Publication
27909050 | J:239239
First Author: Bhagat TD
Year: 2017
Journal: J Biol Chem
Title: Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.
Volume: 292
Issue: 3
Pages: 837-846
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Publication
27150457 | J:253838
 
First Author: Torres-Capelli M
Year: 2016
Journal: Sci Rep
Title: Role Of Hif2α Oxygen Sensing Pathway In Bronchial Epithelial Club Cell Proliferation.
Volume: 6
Pages: 25357
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Publication
9931330 | J:52877
First Author: Hemberger M
Year: 1999
Journal: Hum Mol Genet
Title: Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in fetal and adult mouse tissues.
Volume: 8
Issue: 2
Pages: 229-36
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Publication
26123588 | J:236514
 
First Author: Lepoutre-Lussey C
Year: 2016
Journal: Mol Cell Endocrinol
Title: From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma.
Volume: 421
Pages: 40-8
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Publication
26348575 | J:226906
First Author: Mangiavini L
Year: 2015
Journal: Am J Pathol
Title: Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.
Volume: 185
Issue: 11
Pages: 3090-101
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Publication
16537898 | J:106926
First Author: Tang N
Year: 2006
Journal: Mol Cell Biol
Title: pVHL function is essential for endothelial extracellular matrix deposition.
Volume: 26
Issue: 7
Pages: 2519-30
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Publication
28112274 | J:275118
 
First Author: Gardner PJ
Year: 2017
Journal: Sci Rep
Title: Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.
Volume: 7
Pages: 40830
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Publication
31613797 | J:298369
 
First Author: Wei R
Year: 2019
Journal: JCI Insight
Title: Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.
Volume: 4
Issue: 22
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Publication
38512983 | J:346437
First Author: Myszczyszyn A
Year: 2024
Journal: PLoS One
Title: Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors.
Volume: 19
Issue: 3
Pages: e0282938
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Publication
26398496 | J:236849
First Author: Gerl K
Year: 2015
Journal: Kidney Int
Title: Inducible glomerular erythropoietin production in the adult kidney.
Volume: 88
Issue: 6
Pages: 1345-1355
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Publication
16510575 | J:106705
First Author: Rankin EB
Year: 2006
Journal: Cancer Res
Title: Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor.
Volume: 66
Issue: 5
Pages: 2576-83
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Publication
20522651 | J:162099
First Author: Steenhard BM
Year: 2010
Journal: Am J Pathol
Title: Deletion of von Hippel-Lindau in glomerular podocytes results in glomerular basement membrane thickening, ectopic subepithelial deposition of collagen {alpha}1{alpha}2{alpha}1(IV), expression of neuroglobin, and proteinuria.
Volume: 177
Issue: 1
Pages: 84-96
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Publication
34556788 | J:312362
First Author: Todd VM
Year: 2021
Journal: Commun Biol
Title: Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner.
Volume: 4
Issue: 1
Pages: 1122
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Publication
20197624 | J:158732
First Author: Hickey MM
Year: 2010
Journal: J Clin Invest
Title: The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.
Volume: 120
Issue: 3
Pages: 827-39
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Publication
28118605 | J:274382
First Author: Kantari-Mimoun C
Year: 2017
Journal: Oncotarget
Title: Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice.
Volume: 8
Issue: 9
Pages: 15085-15100
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Publication
24940620 | J:218958
First Author: Zhang LF
Year: 2014
Journal: PLoS One
Title: Osteoblast-secreted factors promote proliferation and osteogenic differentiation of bone marrow stromal cells via VEGF/heme-oxygenase-1 pathway.
Volume: 9
Issue: 6
Pages: e99946
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Publication
16407833 | J:108778
First Author: Giles RH
Year: 2006
Journal: Oncogene
Title: Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis.
Volume: 25
Issue: 21
Pages: 3065-70
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Publication
31181196 | J:280347
 
First Author: Schori C
Year: 2019
Journal: Exp Eye Res
Title: A chronic hypoxic response in photoreceptors alters the vitreous proteome in mice.
Volume: 185
Pages: 107690
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Publication
32807776 | J:303341
First Author: Hoefflin R
Year: 2020
Journal: Nat Commun
Title: HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Volume: 11
Issue: 1
Pages: 4111
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Publication
15798202 | J:97652
First Author: Rankin EB
Year: 2005
Journal: Mol Cell Biol
Title: Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.
Volume: 25
Issue: 8
Pages: 3163-72
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Publication
18439915 | J:136664
First Author: Shah YM
Year: 2008
Journal: Gastroenterology
Title: Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Volume: 134
Issue: 7
Pages: 2036-48, 2048.e1-3
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Publication
21447692 | J:181428
First Author: Lange C
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Normoxic activation of hypoxia-inducible factors in photoreceptors provides transient protection against light-induced retinal degeneration.
Volume: 52
Issue: 8
Pages: 5872-80
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Publication
26759234 | J:231634
First Author: Schönenberger D
Year: 2016
Journal: Cancer Res
Title: Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α.
Volume: 76
Issue: 7
Pages: 2025-36
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Publication
22150821 | J:196860
First Author: Zhang J
Year: 2012
Journal: Clin Exp Pharmacol Physiol
Title: Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality.
Volume: 39
Issue: 2
Pages: 145-50
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Publication
18285456 | J:136012
First Author: Lei L
Year: 2008
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein.
Volume: 28
Issue: 11
Pages: 3790-803
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Publication
22419665 | J:185744
First Author: Xue X
Year: 2012
Journal: Cancer Res
Title: Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis.
Volume: 72
Issue: 9
Pages: 2285-93
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Publication
16129783 | J:100984
First Author: Mekhail K
Year: 2005
Journal: J Cell Biol
Title: Regulation of ubiquitin ligase dynamics by the nucleolus.
Volume: 170
Issue: 5
Pages: 733-44
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Publication
27997827 | J:237617
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
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Publication
27126173 | J:241555
First Author: Guinot A
Year: 2016
Journal: J Pathol
Title: Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.
Volume: 239
Issue: 3
Pages: 365-73
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Publication
29514656 | J:280346
First Author: Barben M
Year: 2018
Journal: Mol Neurodegener
Title: Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia.
Volume: 13
Issue: 1
Pages: 12
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Publication
15601820 | J:94679
First Author: Kamura T
Year: 2004
Journal: Genes Dev
Title: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Volume: 18
Issue: 24
Pages: 3055-65
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Publication
20388654 | J:160163
First Author: Kurihara T
Year: 2010
Journal: Development
Title: von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina.
Volume: 137
Issue: 9
Pages: 1563-71
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Publication
25186293 | J:218695
First Author: Soggia A
Year: 2014
Journal: Diabetologia
Title: von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation.
Volume: 57
Issue: 11
Pages: 2348-56
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Publication
31142573 | J:276713
First Author: Cargill K
Year: 2019
Journal: J Am Soc Nephrol
Title: Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation.
Volume: 30
Issue: 7
Pages: 1192-1205
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Publication
28527294 | J:243840
First Author: Gerl K
Year: 2017
Journal: Am J Pathol
Title: Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.
Volume: 187
Issue: 7
Pages: 1496-1511
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Publication
22627278 | J:185536
First Author: Lange CA
Year: 2012
Journal: Development
Title: Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.
Volume: 139
Issue: 13
Pages: 2340-50
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Publication
32733884 | J:302030
 
First Author: Eberhart T
Year: 2020
Journal: Front Cell Dev Biol
Title: Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression.
Volume: 8
Pages: 566
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Protein Domain
IPR036208 | VHL_sf
Type: Homologous_superfamily
Description: von Hippel-Landau (pVHL) protein, the gene product of VHL, is a critical regulator of the ubiquitous oxygen-sensing pathway. It is conserved throughout evolution, as its homologs are found in organisms ranging from mammals to Drosophila and Caenorhabditis. pVHL acts as the substrate recognition component of an E3 ubiquitin ligase complex. Several proteins have been identified as pVHL-binding proteins that are subject to ubiquitin-mediated proteolysis; the best characterized putative substrates are the alpha subunits of the hypoxia-inducible factor (HIF1alpha, HIF2alpha, and HIF3alpha). In addition to HIF degradation, pVHL has been implicated to be involved in HIF independent cellular processes. Germline VHL mutations cause renal cell carcinomas, hemangioblastomas and pheochromocytomas in humans. pVHL can bind to and direct the proper deposition of fibronectin and collagen IV within the extracellular matrix. It works to stabilize microtubules and foster the maintenance of primary cilium. It also has been reported to promote the stabilization and activation of p53 in a HIF-independent manner and, in neuronal cells, promote apoptosis by down-regulation of Jun-B [, , , , , , , , , , , , , ,, , , , , ].Von Hippel-Lindau disease tumor suppressor (VHL) has two domains: a roughly 100-residue N-terminal domain rich in beta sheet (beta domain) and a smaller α-helical domain (alpha domain), held together by two linkers and a polar interface. A large portion of the alpha domain surface, and a small portion of the beta domain, interact with ElonginC. About half of the tumorigenic mutations map to the alpha domain and its residues that contact ElonginC. The remaining mutations map to the beta domain, and significantly, to a beta domain surface patch uninvolved in ElonginC binding. This suggests that two intact macromolecular binding sites may be required for the tumor suppressor effects of VHL [].
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Protein Coding Gene
MGP_CAROLIEiJ_G0028736 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_103223 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031599 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022487 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029764 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22977222 | J:193425
First Author: Neary MT
Year: 2013
Journal: Dis Model Mech
Title: A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome.
Volume: 6
Issue: 2
Pages: 503-7
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Publication
35666812 | J:326991
First Author: Nguyen TN
Year: 2022
Journal: Cancer Res
Title: IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma.
Volume: 82
Issue: 15
Pages: 2716-2733
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Publication
26488390 | J:250866
First Author: Zhou Q
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.
Volume: 54
Issue: 5
Pages: 728-39
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Publication
27422990 | J:236548
First Author: Slingo M
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.
Volume: 311
Issue: 3
Pages: H759-67
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Publication
19808020 | J:153662
First Author: Chan SY
Year: 2009
Journal: Cell Metab
Title: MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2.
Volume: 10
Issue: 4
Pages: 273-84
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Publication
35118061 | J:326679
 
First Author: Chen K
Year: 2021
Journal: Front Cell Dev Biol
Title: Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation.
Volume: 9
Pages: 721561
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Publication
25825391 | J:229258
First Author: White K
Year: 2015
Journal: EMBO Mol Med
Title: Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
Volume: 7
Issue: 6
Pages: 695-713
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Publication
18199804 | J:150172
First Author: Thorner PS
Year: 2008
Journal: J Am Soc Nephrol
Title: Podocytes contribute to the formation of glomerular crescents.
Volume: 19
Issue: 3
Pages: 495-502
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Publication
8603073 | J:32429
First Author: Gnarra JR
Year: 1996
Journal: Biochim Biophys Acta
Title: Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma.
Volume: 1242
Issue: 3
Pages: 201-10
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Publication
10353237 | J:55034
First Author: Kaelin WG Jr
Year: 1999
Journal: Nature
Title: Cancer. Many vessels, faulty gene.
Volume: 399
Issue: 6733
Pages: 203-4
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Publication
21652636 | J:183052
First Author: Sinha S
Year: 2011
Journal: J Cell Sci
Title: Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.
Volume: 124
Issue: Pt 13
Pages: 2132-42
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GXD Expression
GXD Expression
     
Probe: MGI:6444444
Assay Type: RT-PCR
Annotation Date: 2020-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6446189
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6444444
Assay Type: RT-PCR
Annotation Date: 2020-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6446189
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Vhlfl/fl
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Vhlfl/fl
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Vhlfl/fl
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Sox9-Cre;Vhlfl/wt
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Sox9-Cre;Vhlfl/wt
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Sox9-Cre;Vhlfl/wt
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Sox9-Cre;Vhlfl/fl
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Sox9-Cre;Vhlfl/fl
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492316
Assay Type: Western blot
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7492360
Age: embryonic day 18.5
Specimen Label: Sox9-Cre;Vhlfl/fl
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492318
Assay Type: RT-PCR
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7492372
Age: embryonic day 14.5
Specimen Label: control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492318
Assay Type: RT-PCR
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:7492372
Age: embryonic day 14.5
Specimen Label: Sox9-Cre
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492318
Assay Type: RT-PCR
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Stage: TS25
Assay Id: MGI:7492399
Age: embryonic day 17.5
Specimen Label: Vhlfl/wt
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492318
Assay Type: RT-PCR
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Stage: TS25
Assay Id: MGI:7492399
Age: embryonic day 17.5
Specimen Label: Sox9-Cre;Vhlfl/wt
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7492318
Assay Type: RT-PCR
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Stage: TS25
Assay Id: MGI:7492399
Age: embryonic day 17.5
Specimen Label: Sox9-CreVhlfl/fl
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3807493
Assay Type: RNA in situ
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3807494
Age: embryonic day 13.5
Specimen Label: 1J
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3807493
Assay Type: RNA in situ
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3807494
Age: embryonic day 16.5
Specimen Label: 3N
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3807493
Assay Type: RNA in situ
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3807494
Age: embryonic day 16.5
Note: Expression is present in the neuroepithlium.
Specimen Label: 3F
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3807493
Assay Type: RNA in situ
Annotation Date: 2008-09-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1876724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3807494
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3807493
Assay Type: RNA in situ
Annotation Date: 2008-09-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1737324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3807494
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3807493
Assay Type: RNA in situ
Annotation Date: 2008-09-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1737321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3807494
Age: embryonic day 13.5
Specimen Label: 1J
Detected: true
Specimen Num: 5
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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