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Search results 1 to 100 out of 179 for Egln1

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Category: Publication
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Type Details Score
Publication
- | J:70779
   
First Author: Taylor MS
Year: 2001
Journal: GenBank Submission
Title: Mus musculus partial mRNA for EGLN1 protein
Pages: AJ310546
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Publication
26919427 | J:230798
First Author: Olenchock BA
Year: 2016
Journal: Cell
Title: EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.
Volume: 164
Issue: 5
Pages: 884-95
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Publication
19683511 | J:155629
First Author: Ozolins TR
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Defects in embryonic development of EGLN1/PHD2 knockdown transgenic mice are associated with induction of Igfbp in the placenta.
Volume: 390
Issue: 3
Pages: 372-6
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Publication
37400498 | J:341078
First Author: Zhang T
Year: 2023
Journal: Nat Cell Biol
Title: Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Volume: 25
Issue: 7
Pages: 950-962
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Publication
11574160 | J:72041
First Author: Taylor MS
Year: 2001
Journal: Gene
Title: Characterization and comparative analysis of the EGLN gene family.
Volume: 275
Issue: 1
Pages: 125-32
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Publication
27143681 | J:243976
First Author: Dai Z
Year: 2016
Journal: Circulation
Title: Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α.
Volume: 133
Issue: 24
Pages: 2447-58
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Publication
24360282 | J:205482
First Author: Gomes AP
Year: 2013
Journal: Cell
Title: Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Volume: 155
Issue: 7
Pages: 1624-38
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Publication
18096761 | J:132718
First Author: Minamishima YA
Year: 2008
Journal: Blood
Title: Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.
Volume: 111
Issue: 6
Pages: 3236-44
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Publication
27325674 | J:236168
First Author: Arsenault PR
Year: 2016
Journal: Mol Cell Biol
Title: The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.
Volume: 36
Issue: 18
Pages: 2328-43
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Publication
29074488 | J:258206
First Author: Tang H
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Volume: 314
Issue: 2
Pages: L256-L275
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Publication
24121508 | J:202737
First Author: Arsenault PR
Year: 2013
Journal: J Biol Chem
Title: A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism.
Volume: 288
Issue: 47
Pages: 33571-84
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Publication
18500250 | J:180457
First Author: Wu S
Year: 2008
Journal: Mol Ther
Title: Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.
Volume: 16
Issue: 7
Pages: 1227-34
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Publication
21435465 | J:169844
First Author: Duan LJ
Year: 2011
Journal: Am J Pathol
Title: Prolyl hydroxylase domain protein 2 (PHD2) mediates oxygen-induced retinopathy in neonatal mice.
Volume: 178
Issue: 4
Pages: 1881-90
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Publication
28266128 | J:271834
First Author: Wang S
Year: 2017
Journal: J Cell Mol Med
Title: Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice.
Volume: 21
Issue: 9
Pages: 1967-1978
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Publication
30036883 | J:304486
First Author: Zhou LY
Year: 2018
Journal: Cell Physiol Biochem
Title: Regulatory Role of Endothelial PHD2 in the Hepatic Steatosis.
Volume: 48
Issue: 3
Pages: 1003-1011
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Publication
27613846 | J:274430
First Author: Wang S
Year: 2016
Journal: Oncotarget
Title: Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling.
Volume: 7
Issue: 37
Pages: 58848-58861
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Publication
25546437 | J:225375
First Author: Zeng H
Year: 2014
Journal: PLoS One
Title: Conditional knockout of prolyl hydroxylase domain protein 2 attenuates high fat-diet-induced cardiac dysfunction in mice.
Volume: 9
Issue: 12
Pages: e115974
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Publication
26235614 | J:227777
First Author: Kuchnio A
Year: 2015
Journal: Cell Rep
Title: The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts.
Volume: 12
Issue: 6
Pages: 992-1005
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Publication
27533040 | J:236607
First Author: Thienpont B
Year: 2016
Journal: Nature
Title: Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Volume: 537
Issue: 7618
Pages: 63-68
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Publication
30339838 | J:270446
First Author: Fan Q
Year: 2019
Journal: Am J Pathol
Title: Prolyl Hydroxylase Domain-2 Protein Regulates Lipopolysaccharide-Induced Vascular Inflammation.
Volume: 189
Issue: 1
Pages: 200-213
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Publication
27775044 | J:259914
 
First Author: Cheng S
Year: 2016
Journal: Sci Rep
Title: Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice.
Volume: 6
Pages: 35748
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Publication
26562260 | J:233631
First Author: Cheng S
Year: 2016
Journal: Endocrinology
Title: Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.
Volume: 157
Issue: 1
Pages: 127-40
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Publication
30910827 | J:274884
 
First Author: Duan LJ
Year: 2019
Journal: Development
Title: Developmental vascular pruning in neonatal mouse retinas is programmed by the astrocytic oxygen-sensing mechanism.
Volume: 146
Issue: 8
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26324945 | J:226915
First Author: Suhara T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle.
Volume: 112
Issue: 37
Pages: 11642-7
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24695462 | J:215034
First Author: Zimmermann AS
Year: 2014
Journal: PLoS One
Title: Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury.
Volume: 9
Issue: 4
Pages: e93373
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29688249 | J:320877
First Author: Xie Y
Year: 2018
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice.
Volume: 50
Issue: 6
Pages: 540-546
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Publication
23630130 | J:211391
First Author: Matsuura H
Year: 2013
Journal: Circulation
Title: Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance.
Volume: 127
Issue: 21
Pages: 2078-87
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Publication
19217150 | J:148719
First Author: Mazzone M
Year: 2009
Journal: Cell
Title: Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Volume: 136
Issue: 5
Pages: 839-851
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27789456 | J:240899
First Author: Manresa MC
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].
Volume: 311
Issue: 6
Pages: G1076-G1090
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24789921 | J:229849
First Author: Rahtu-Korpela L
Year: 2014
Journal: Diabetes
Title: HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction.
Volume: 63
Issue: 10
Pages: 3324-33
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26452676 | J:268773
First Author: Karsikas S
Year: 2016
Journal: J Mol Med (Berl)
Title: HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.
Volume: 94
Issue: 3
Pages: 301-10
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23775121 | J:204721
First Author: Kerkelä R
Year: 2013
Journal: Mol Cell Biol
Title: Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection.
Volume: 33
Issue: 16
Pages: 3321-9
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Publication
34919895 | J:321557
 
First Author: Röning T
Year: 2022
Journal: J Mol Cell Cardiol
Title: Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy.
Volume: 164
Pages: 148-155
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32413092 | J:289394
First Author: Settelmeier S
Year: 2020
Journal: PLoS One
Title: Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice.
Volume: 15
Issue: 5
Pages: e0233261
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32100354 | J:304948
First Author: Laitakari A
Year: 2020
Journal: FASEB J
Title: Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span.
Volume: 34
Issue: 4
Pages: 5590-5609
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11056053 | J:65642
First Author: Dupuy D
Year: 2000
Journal: Genomics
Title: Mapping, characterization, and expression analysis of the SM-20 human homologue, c1orf12, and identification of a novel related gene, SCAND2.
Volume: 69
Issue: 3
Pages: 348-54
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27720797 | J:236780
 
First Author: Gruneberg D
Year: 2016
Journal: Exp Neurol
Title: Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion.
Volume: 286
Pages: 93-106
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31162141 | J:289312
First Author: Yamamoto A
Year: 2019
Journal: J Clin Invest
Title: Systemic silencing of PHD2 causes reversible immune regulatory dysfunction.
Volume: 129
Issue: 9
Pages: 3640-3656
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Publication
34422822 | J:335342
 
First Author: Zhu J
Year: 2021
Journal: Front Cell Dev Biol
Title: Hypoxia-Inducible Factor 2-Alpha Mediated Gene Sets Differentiate Pulmonary Arterial Hypertension.
Volume: 9
Pages: 701247
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27827416 | J:254086
 
First Author: Futatsugi K
Year: 2016
Journal: Sci Rep
Title: Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules.
Volume: 6
Pages: 36533
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25647640 | J:330470
First Author: Hellfritsch J
Year: 2015
Journal: Antioxid Redox Signal
Title: Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Volume: 22
Issue: 11
Pages: 938-50
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24990963 | J:212076
First Author: Zheng X
Year: 2014
Journal: Genes Dev
Title: Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
Volume: 28
Issue: 13
Pages: 1429-44
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Publication
32715763 | J:296776
First Author: Zhao Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury.
Volume: 319
Issue: 2
Pages: F345-F357
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Publication
26868537 | J:263576
 
First Author: Zeng H
Year: 2016
Journal: Sci Rep
Title: LPS causes pericyte loss and microvascular dysfunction via disruption of Sirt3/angiopoietins/Tie-2 and HIF-2α/Notch3 pathways.
Volume: 6
Pages: 20931
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30444491 | J:267502
   
First Author: Elamaa H
Year: 2018
Journal: Elife
Title: Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina.
Volume: 7
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28805660 | J:247852
First Author: Sadiku P
Year: 2017
Journal: J Clin Invest
Title: Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.
Volume: 127
Issue: 9
Pages: 3407-3420
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21346252 | J:173281
First Author: Nytko KJ
Year: 2011
Journal: Blood
Title: Vitamin C is dispensable for oxygen sensing in vivo.
Volume: 117
Issue: 20
Pages: 5485-93
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31390373 | J:279103
First Author: Lindsey RC
Year: 2019
Journal: PLoS One
Title: Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2.
Volume: 14
Issue: 8
Pages: e0220653
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23778187 | J:199066
First Author: Ikeda J
Year: 2013
Journal: J Am Heart Assoc
Title: Deletion of phd2 in myeloid lineage attenuates hypertensive cardiovascular remodeling.
Volume: 2
Issue: 3
Pages: e000178
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10543731 | J:60099
First Author: Moschella MC
Year: 1999
Journal: Gene Expr
Title: SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation.
Volume: 8
Issue: 1
Pages: 59-66
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26863487 | J:233029
First Author: Stegen S
Year: 2016
Journal: Cell Metab
Title: HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival.
Volume: 23
Issue: 2
Pages: 265-79
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21983962 | J:268782
First Author: Takeda Y
Year: 2011
Journal: Nature
Title: Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis.
Volume: 479
Issue: 7371
Pages: 122-6
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26848160 | J:246928
First Author: Rahtu-Korpela L
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis.
Volume: 36
Issue: 4
Pages: 608-17
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29601782 | J:280645
First Author: Luo B
Year: 2018
Journal: FASEB J
Title: Hepatic PHD2/HIF-1α axis is involved in postexercise systemic energy homeostasis.
Volume: 32
Issue: 9
Pages: 4670-4680
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23913502 | J:231998
First Author: Mamlouk S
Year: 2014
Journal: Int J Cancer
Title: Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development.
Volume: 134
Issue: 4
Pages: 849-58
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Publication
23798557 | J:204713
First Author: Kalucka J
Year: 2013
Journal: Mol Cell Biol
Title: Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice.
Volume: 33
Issue: 17
Pages: 3426-38
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37140003 | J:338024
First Author: Rosiewicz KS
Year: 2023
Journal: Glia
Title: HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Volume: 71
Issue: 8
Pages: 2024-2044
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Publication
30575721 | J:270317
First Author: Liu S
Year: 2018
Journal: Nat Commun
Title: Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis.
Volume: 9
Issue: 1
Pages: 5426
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30651640 | J:270606
First Author: Stegen S
Year: 2019
Journal: Nature
Title: HIF-1α metabolically controls collagen synthesis and modification in chondrocytes.
Volume: 565
Issue: 7740
Pages: 511-515
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24220244 | J:206742
First Author: Laoui D
Year: 2014
Journal: Cancer Res
Title: Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.
Volume: 74
Issue: 1
Pages: 24-30
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29967369 | J:266095
First Author: Stegen S
Year: 2018
Journal: Nat Commun
Title: Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin.
Volume: 9
Issue: 1
Pages: 2557
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Publication
27821476 | J:244936
 
First Author: Myllymäki MN
Year: 2017
Journal: Mol Cell Biol
Title: Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice.
Volume: 37
Issue: 2
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Publication
10795925 | J:62450
 
First Author: Murphy D
Year: 2000
Journal: Exp Physiol
Title: Transgenic studies in rats and mice on the osmotic regulation of vasopressin gene expression.
Volume: 85 Spec No
Pages: 211S-222S
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37847687 | J:342470
First Author: Barnes EA
Year: 2023
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension.
Volume: 325
Issue: 6
Pages: L741-L755
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Publication
19720742 | J:153985
First Author: Minamishima YA
Year: 2009
Journal: Mol Cell Biol
Title: A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
Volume: 29
Issue: 21
Pages: 5729-41
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26818499 | J:229447
First Author: Rajagopalan S
Year: 2016
Journal: J Neurosci
Title: Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
Volume: 36
Issue: 4
Pages: 1086-95
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31029587 | J:274809
 
First Author: Leinonen H
Year: 2019
Journal: Neuropharmacology
Title: Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice.
Volume: 153
Pages: 63-72
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27082941 | J:332230
First Author: Rauner M
Year: 2016
Journal: J Bone Miner Res
Title: Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells.
Volume: 31
Issue: 10
Pages: 1877-1887
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20733101 | J:179490
First Author: Moslehi J
Year: 2010
Journal: Circulation
Title: Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Volume: 122
Issue: 10
Pages: 1004-16
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Publication
23476056 | J:213317
First Author: Matsushima S
Year: 2013
Journal: Circ Res
Title: Broad suppression of NADPH oxidase activity exacerbates ischemia/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1α and upregulation of peroxisome proliferator-activated receptor-α.
Volume: 112
Issue: 8
Pages: 1135-49
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27981571 | J:241898
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
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28716863 | J:247886
First Author: Tavernier SJ
Year: 2017
Journal: J Leukoc Biol
Title: Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages.
Volume: 102
Issue: 4
Pages: 1115-1126
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32814068 | J:301250
 
First Author: Smaila BD
Year: 2020
Journal: Exp Neurol
Title: Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury.
Volume: 334
Pages: 113436
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24508125 | J:208042
First Author: Duan LJ
Year: 2014
Journal: Am J Pathol
Title: Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver.
Volume: 184
Issue: 4
Pages: 1240-50
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Publication
33819286 | J:304962
First Author: Wei GZ
Year: 2021
Journal: PLoS One
Title: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
Volume: 16
Issue: 4
Pages: e0249591
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24440788 | J:206444
First Author: Takeda K
Year: 2014
Journal: Am J Pathol
Title: Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism.
Volume: 184
Issue: 3
Pages: 686-96
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Publication
24037093 | J:202021
First Author: Taniguchi CM
Year: 2013
Journal: Nat Med
Title: Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes.
Volume: 19
Issue: 10
Pages: 1325-30
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33298456 | J:313923
 
First Author: Byts N
Year: 2021
Journal: eNeuro
Title: Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes.
Volume: 8
Issue: 1
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30248340 | J:270770
First Author: Strowitzki MJ
Year: 2018
Journal: Am J Pathol
Title: Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells.
Volume: 188
Issue: 12
Pages: 2826-2838
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Publication
28418093 | J:243598
First Author: Hulley PA
Year: 2017
Journal: J Pathol
Title: Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2.
Volume: 242
Issue: 3
Pages: 322-333
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Publication
26774962 | J:232857
First Author: Quaegebeur A
Year: 2016
Journal: Cell Metab
Title: Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
23690557 | J:212783
First Author: Bishop T
Year: 2013
Journal: J Physiol
Title: Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Volume: 591
Issue: 14
Pages: 3565-77
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Publication
20600011 | J:309903
First Author: Tambuwala MM
Year: 2010
Journal: Gastroenterology
Title: Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Volume: 139
Issue: 6
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