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Search results 201 to 292 out of 292 for Xdh

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Type Details Score
Publication
30312761 | J:294458
 
First Author: Lindsay A
Year: 2018
Journal: Free Radic Biol Med
Title: Xanthine oxidase is hyper-active in Duchenne muscular dystrophy.
Volume: 129
Pages: 364-371
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Publication
21310927 | J:173284
First Author: Troadec MB
Year: 2011
Journal: Blood
Title: Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.
Volume: 117
Issue: 20
Pages: 5494-502
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Publication
32239172 | J:288975
First Author: Ristic B
Year: 2020
Journal: Biochem J
Title: Hereditary hemochromatosis disrupts uric acid homeostasis and causes hyperuricemia via altered expression/activity of xanthine oxidase and ABCG2.
Volume: 477
Issue: 8
Pages: 1499-1513
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Publication
22095983 | J:195970
First Author: Kushiyama A
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development.
Volume: 32
Issue: 2
Pages: 291-8
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Publication
17597094 | J:129870
First Author: Martelli A
Year: 2007
Journal: Hum Mol Genet
Title: Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues.
Volume: 16
Issue: 22
Pages: 2651-8
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Publication
8064675 | J:297526
First Author: Alexiou M
Year: 1994
Journal: J Reprod Fertil
Title: Enzymes of purine salvage and catabolism in the mouse preimplantation embryo measured by high performance liquid chromatography.
Volume: 101
Issue: 1
Pages: 151-8
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Publication
9169125 | J:37740
First Author: Lin HH
Year: 1997
Journal: Genomics
Title: Identification and characterization of a seven transmembrane hormone receptor using differential display.
Volume: 41
Issue: 3
Pages: 301-8
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Publication
27609225 | J:325877
 
First Author: Peleli M
Year: 2016
Journal: Free Radic Biol Med
Title: Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis.
Volume: 99
Pages: 472-484
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Publication
19800018 | J:217280
First Author: Beigi F
Year: 2009
Journal: Nitric Oxide
Title: Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, CAPON.
Volume: 21
Issue: 3-4
Pages: 226-33
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Publication
8661125 | J:33929
First Author: Doyle J
Year: 1996
Journal: Genomics
Title: Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins.
Volume: 35
Issue: 1
Pages: 227-30
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Publication
8562047 | J:28424
First Author: Palis J
Year: 1995
Journal: Mol Reprod Dev
Title: Differential gene expression during early murine yolk sac development.
Volume: 42
Issue: 1
Pages: 19-27
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Publication
10753524 | J:61711
First Author: Ulven SM
Year: 2000
Journal: Dev Biol
Title: Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.
Volume: 220
Issue: 2
Pages: 379-91
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Publication
15857914 | J:98484
First Author: Lickert H
Year: 2005
Journal: Development
Title: Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos.
Volume: 132
Issue: 11
Pages: 2599-609
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Publication
27914912 | J:240319
First Author: Stauber M
Year: 2017
Journal: Dev Biol
Title: Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Volume: 423
Issue: 2
Pages: 170-188
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Xdh<em1Smoc> | MGI:7293201
Name: xanthine dehydrogenase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
Q64442
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: false
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DO Term
DOID:0070452 | xanthinuria type I
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Protein Domain
IPR017609 | Xanthine_dehydrogenase_dsu
Type: Family
Description: This gene has been characterised in Bacillus subtilis []as the molybdopterin binding-subunit of xanthine dehydrogenase (pucD), acting in conjunction with pucC, the FAD-binding subunit and pucE, the FeS-binding subunit. The more common XDH complex () includes the xdhB gene which is related to pucD. It appears that most of the relatives of pucD outside of this narrow clade are involved in other processes as they are found in unrelated genomic contexts, contain the more common XDH complex and/or do not appear to process purines to allantoin.
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Protein Domain
IPR017615 | Xanthine_dehydrogenase_PucB
Type: Family
Description: Members of this protein family are PucB proteins found in Bacillus subtilis []. The expression of this protein is located in an operon with the structural subunits of xanthine dehydrogenase, and has been found to be essential for XDH activity. Some members of this family appear to have a distant relationship to the MobA protein involved in molybdopterin biosynthesis, although this may be coincidental.
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Protein Domain
IPR017611 | Xanthine_dehydrogenase_esu
Type: Family
Description: This protein has been characterised in Bacillus subtilis []as the iron-sulphur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex () includes the xdhA gene as the Fe-S cluster binding component.
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Publication
11344136 | -
First Author: Schultz AC
Year: 2001
Journal: J Bacteriol
Title: Functional analysis of 14 genes that constitute the purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator.
Volume: 183
Issue: 11
Pages: 3293-302
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Publication
11307944 | J:69077
First Author: Tsuchida S
Year: 2001
Journal: J Vet Med Sci
Title: Molecular cloning of a cDNA coding for feline liver xanthine dehydrogenase.
Volume: 63
Issue: 3
Pages: 353-5
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Publication
11302742 | J:337081
First Author: Ichida K
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Mutation of human molybdenum cofactor sulfurase gene is responsible for classical xanthinuria type II.
Volume: 282
Issue: 5
Pages: 1194-200
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Publication
31953403 | J:285640
First Author: Zhao L
Year: 2020
Journal: Nat Commun
Title: TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh.
Volume: 11
Issue: 1
Pages: 341
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Protein Domain
IPR016208 | Ald_Oxase/xanthine_DH
Type: Family
Description: This entry includes aldehyde oxidases (AOXs) and xanthine dehydrogenases (XDHs). They are both molybdenum cofactor (Moco) containing enzymes []. AOX catalyses the reaction:aldehyde + H(2)O + O(2) = a carboxylic acid + H2O2 It binds 2 2Fe-2S clusters uses FAD and molybdopterin as cofactors. XDH has the same cofactors and some of them can be converted from the dehydrogenase form (D) to the oxidase form (O). This can be done irreversibly by proteolysis or reversibly through the oxidation of sulfhydryl groups []. This enzyme catalyses three reactions:Xanthine + H2O + NAD+= urate + NADHHypoxanthine + H2O + NAD+= xanthine + NADHXanthine + H2O + O2 = urate + H2O2In Arabidopsis thaliana, the molybdenum cofactor sulfurase ABA3 is needed for post-translational activation of aldehyde oxidase and xanthine dehydrogenase. It does this by transferring a sulfur atom to the desulfo-molybdenum cofactor of these enzymes [, ].
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Publication
22245780 | J:181181
First Author: Wang W
Year: 2012
Journal: Nat Med
Title: Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids.
Volume: 18
Issue: 2
Pages: 235-43
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Publication
31971609 | J:340387
First Author: Hosoya T
Year: 2020
Journal: Br J Pharmacol
Title: Perfecting a high hypoxanthine phosphoribosyltransferase activity-uricase KO mice to test the effects of purine- and non-purine-type xanthine dehydrogenase (XDH) inhibitors.
Volume: 177
Issue: 10
Pages: 2274-2285
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Publication
9689017 | J:111451
First Author: Stockelman MG
Year: 1998
Journal: Am J Physiol
Title: Chronic renal failure in a mouse model of human adenine phosphoribosyltransferase deficiency.
Volume: 275
Issue: 1 Pt 2
Pages: F154-63
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Publication
17023262 | J:114514
First Author: Schröder K
Year: 2006
Journal: Free Radic Biol Med
Title: Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.
Volume: 41
Issue: 9
Pages: 1353-60
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Publication
33023155 | J:299757
 
First Author: Key J
Year: 2020
Journal: Cells
Title: Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.
Volume: 9
Issue: 10
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Publication
18258600 | -
First Author: Wollers S
Year: 2008
Journal: J Biol Chem
Title: Binding of sulfurated molybdenum cofactor to the C-terminal domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.
Volume: 283
Issue: 15
Pages: 9642-50
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Publication
27406959 | J:43556
First Author: Wright RM
Year: 1997
Journal: Redox Rep
Title: Molecular cloning, refined chromosomal mapping and structural analysis of the human gene encoding aldehyde oxidase (AOX1), a candidate for the ALS2 gene.
Volume: 3
Issue: 3
Pages: 135-44
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Publication
17649978 | -
First Author: Neumann M
Year: 2007
Journal: Biochemistry
Title: Identification of a Rhodobacter capsulatus L-cysteine desulfurase that sulfurates the molybdenum cofactor when bound to XdhC and before its insertion into xanthine dehydrogenase.
Volume: 46
Issue: 33
Pages: 9586-95
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Protein
Q9CVF2
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: true
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Protein
A0A3B2WBF8
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: true
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Protein
A0A087WQC8
Organism: Mus musculus/domesticus
Length: 270  
Fragment?: false
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Protein
Q8C6Q4
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: true
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Protein
Q3TAT6
Organism: Mus musculus/domesticus
Length: 356  
Fragment?: true
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Protein
Q3TP30
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
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Publication
27537049 | -
First Author: Wang CH
Year: 2016
Journal: Bioengineered
Title: Xanthine dehydrogenase: An old enzyme with new knowledge and prospects.
Volume: 7
Issue: 6
Pages: 395-405
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Protein
Q3UV07
Organism: Mus musculus/domesticus
Length: 319  
Fragment?: false
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Protein
Q9CW59
Organism: Mus musculus/domesticus
Length: 974  
Fragment?: true
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Protein
O54754
Organism: Mus musculus/domesticus
Length: 1333  
Fragment?: false
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Protein
Q3TYQ9
Organism: Mus musculus/domesticus
Length: 1336  
Fragment?: false
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Protein
G3X982
Organism: Mus musculus/domesticus
Length: 1335  
Fragment?: false
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Protein
Q5SGK3
Organism: Mus musculus/domesticus
Length: 1345  
Fragment?: false
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Protein
Q00519
Organism: Mus musculus/domesticus
Length: 1335  
Fragment?: false
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Protein
Q148T8
Organism: Mus musculus/domesticus
Length: 1336  
Fragment?: false
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Protein
G3X8P9
Organism: Mus musculus/domesticus
Length: 1333  
Fragment?: false
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Protein
Q8R387
Organism: Mus musculus/domesticus
Length: 1333  
Fragment?: false
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Protein
Q6V957
Organism: Mus musculus/domesticus
Length: 1336  
Fragment?: false
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Protein
Q9ESH4
Organism: Mus musculus/domesticus
Length: 1336  
Fragment?: false
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Protein
Q6V956
Organism: Mus musculus/domesticus
Length: 1336  
Fragment?: false
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Protein
B2RUJ7
Organism: Mus musculus/domesticus
Length: 1335  
Fragment?: false
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Protein
Q3UMS6
Organism: Mus musculus/domesticus
Length: 1335  
Fragment?: false
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Protein
Q9ES55
Organism: Mus musculus/domesticus
Length: 1336  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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