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Search results 1 to 100 out of 148 for Ptk2b

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Category: Publication
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Type Details Score
Publication
12960403 | J:99741
First Author: Okigaki M
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration.
Volume: 100
Issue: 19
Pages: 10740-5
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Publication
17846174 | J:134795
First Author: Gil-Henn H
Year: 2007
Journal: J Cell Biol
Title: Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice.
Volume: 178
Issue: 6
Pages: 1053-64
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Publication
17537919 | J:122285
First Author: Buckbinder L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis.
Volume: 104
Issue: 25
Pages: 10619-24
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Publication
18391070 | J:134671
First Author: Weis SM
Year: 2008
Journal: J Cell Biol
Title: Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.
Volume: 181
Issue: 1
Pages: 43-50
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Publication
17698736 | J:139849
First Author: Matsui A
Year: 2007
Journal: Circulation
Title: Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function.
Volume: 116
Issue: 9
Pages: 1041-51
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Publication
37989995 | J:342961
First Author: Lin Y
Year: 2023
Journal: Nat Commun
Title: PTK2B promotes TBK1 and STING oligomerization and enhances the STING-TBK1 signaling.
Volume: 14
Issue: 1
Pages: 7567
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Publication
29750960 | J:271421
First Author: Ni B
Year: 2018
Journal: Biochem Biophys Res Commun
Title: A novel role for PTK2B in cultured beige adipocyte differentiation.
Volume: 501
Issue: 4
Pages: 851-857
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Publication
24667605 | J:219473
First Author: Luo J
Year: 2014
Journal: Biochem Biophys Res Commun
Title: PTK2b function during fertilization of the mouse oocyte.
Volume: 450
Issue: 3
Pages: 1212-7
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Publication
32608523 | J:307509
First Author: Cong Y
Year: 2021
Journal: J Cell Physiol
Title: Ptk2b deletion improves mice folliculogenesis and fecundity via inhibiting follicle loss mediated by Erk pathway.
Volume: 236
Issue: 2
Pages: 1043-1053
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Publication
7544443 | -
First Author: Lev S
Year: 1995
Journal: Nature
Title: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions.
Volume: 376
Issue: 6543
Pages: 737-45
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Publication
20332118 | -
First Author: Schaller MD
Year: 2010
Journal: J Cell Sci
Title: Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions.
Volume: 123
Issue: Pt 7
Pages: 1007-13
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Publication
8849729 | -
First Author: Dikic I
Year: 1996
Journal: Nature
Title: A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation.
Volume: 383
Issue: 6600
Pages: 547-50
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Publication
9774338 | -
First Author: Sieg DJ
Year: 1998
Journal: EMBO J
Title: Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
Volume: 17
Issue: 20
Pages: 5933-47
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Publication
19648005 | -
First Author: Allen JG
Year: 2009
Journal: Bioorg Med Chem Lett
Title: Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells.
Volume: 19
Issue: 17
Pages: 4924-8
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Publication
20381867 | -
First Author: Collins M
Year: 2010
Journal: Mol Immunol
Title: T cell receptor activation leads to two distinct phases of Pyk2 activation and actin cytoskeletal rearrangement in human T cells.
Volume: 47
Issue: 9
Pages: 1665-74
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Publication
15888917 | -
First Author: Ostergaard HL
Year: 2005
Journal: Immunol Res
Title: Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function.
Volume: 31
Issue: 3
Pages: 267-82
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Publication
10704819 | -
First Author: Avraham H
Year: 2000
Journal: Cell Signal
Title: RAFTK/Pyk2-mediated cellular signalling.
Volume: 12
Issue: 3
Pages: 123-33
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Publication
18765415 | -
First Author: Sun CK
Year: 2008
Journal: Carcinogenesis
Title: Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation.
Volume: 29
Issue: 11
Pages: 2096-105
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Publication
35501917 | J:332722
First Author: Brody AH
Year: 2022
Journal: Mol Neurodegener
Title: Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.
Volume: 17
Issue: 1
Pages: 32
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Publication
20737507 | J:164222
First Author: Beverdam A
Year: 2010
Journal: Dev Dyn
Title: Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads.
Volume: 239
Issue: 10
Pages: 2735-41
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Publication
10881171 | J:63286
First Author: Guinamard R
Year: 2000
Journal: Nat Immunol
Title: Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response.
Volume: 1
Issue: 1
Pages: 31-6
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Publication
- | J:265543
     
First Author: Suo L
Year: 2017
Journal: bioRxiv
Title: Pyk2 suppresses contextual fear memory in a kinase-independent manner
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Publication
26663135 | J:229315
First Author: Giralt A
Year: 2016
Journal: Glia
Title: Pyk2 is essential for astrocytes mobility following brain lesion.
Volume: 64
Issue: 4
Pages: 620-34
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Publication
28754799 | J:247753
First Author: Llewellyn RA
Year: 2017
Journal: J Leukoc Biol
Title: The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.
Volume: 102
Issue: 4
Pages: 1069-1080
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Publication
31081900 | J:277604
First Author: Sato AY
Year: 2019
Journal: Endocrinology
Title: Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2/Anoikis Signaling.
Volume: 160
Issue: 7
Pages: 1659-1673
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16039993 | J:99955
First Author: Yu Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Role of PYK2 in the development of obesity and insulin resistance.
Volume: 334
Issue: 4
Pages: 1085-91
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28527703 | J:246620
First Author: Wang H
Year: 2017
Journal: Dev Biol
Title: Sperm-oocyte contact induces outside-in signaling via PYK2 activation.
Volume: 428
Issue: 1
Pages: 52-62
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Publication
29428397 | J:265937
 
First Author: Posritong S
Year: 2018
Journal: Mol Cell Endocrinol
Title: Pyk2 deficiency potentiates osteoblast differentiation and mineralizing activity in response to estrogen or raloxifene.
Volume: 474
Pages: 35-47
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Publication
24598361 | J:211002
First Author: Koppel AC
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: Delayed skin wound repair in proline-rich protein tyrosine kinase 2 knockout mice.
Volume: 306
Issue: 10
Pages: C899-909
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Publication
21666110 | J:176931
First Author: Lang D
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Role of Pyk2 in cardiac arrhythmogenesis.
Volume: 301
Issue: 3
Pages: H975-83
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Publication
30518596 | J:270037
First Author: Salazar SV
Year: 2019
Journal: J Neurosci
Title: Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss.
Volume: 39
Issue: 4
Pages: 758-772
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Publication
23175689 | J:194220
First Author: Canobbio I
Year: 2013
Journal: Blood
Title: Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2.
Volume: 121
Issue: 4
Pages: 648-57
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Publication
31677798 | J:291442
First Author: Matsubara L
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Translin restricts the growth of pubertal mammary epithelial cells estrogen-independently in mice.
Volume: 521
Issue: 3
Pages: 562-568
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Publication
22157654 | J:196552
First Author: Sonomura K
Year: 2012
Journal: Kidney Int
Title: The kinase Pyk2 is involved in renal fibrosis by means of mechanical stretch-induced growth factor expression in renal tubules.
Volume: 81
Issue: 5
Pages: 449-57
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Publication
24713463 | J:224957
 
First Author: Koshman YE
Year: 2014
Journal: J Mol Cell Cardiol
Title: Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy.
Volume: 72
Pages: 281-91
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Publication
18198130 | J:131388
First Author: Park MH
Year: 2008
Journal: FEBS Lett
Title: Induction of proline-rich tyrosine kinase2 (Pyk2) through C/EBPbeta is involved in PMA-induced monocyte differentiation.
Volume: 582
Issue: 3
Pages: 415-22
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18084294 | J:131641
First Author: Wang L
Year: 2008
Journal: Nat Immunol
Title: 'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.
Volume: 9
Issue: 2
Pages: 186-93
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18635666 | J:139802
First Author: Xie J
Year: 2008
Journal: Mol Endocrinol
Title: Analysis of the calcium-dependent regulation of proline-rich tyrosine kinase 2 by gonadotropin-releasing hormone.
Volume: 22
Issue: 10
Pages: 2322-35
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19047047 | J:147222
First Author: Chen J
Year: 2009
Journal: J Biol Chem
Title: alpha- and gamma-Protocadherins negatively regulate PYK2.
Volume: 284
Issue: 5
Pages: 2880-90
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22811489 | J:188502
First Author: Fisher KD
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Pyk2 regulates H+-ATPase-mediated proton secretion in the outer medullary collecting duct via an ERK1/2 signaling pathway.
Volume: 303
Issue: 9
Pages: F1353-62
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Publication
27086609 | J:234935
First Author: Meng XQ
Year: 2016
Journal: J Reprod Dev
Title: Subcellular localization of proline-rich tyrosine kinase 2 during oocyte fertilization and early-embryo development in mice.
Volume: 62
Issue: 4
Pages: 351-8
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Publication
29678998 | J:291015
First Author: Zacchia M
Year: 2018
Journal: J Am Soc Nephrol
Title: Acid Stimulation of the Citrate Transporter NaDC-1 Requires Pyk2 and ERK1/2 Signaling Pathways.
Volume: 29
Issue: 6
Pages: 1720-1730
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30664624 | J:295621
First Author: Montalban E
Year: 2019
Journal: Transl Psychiatry
Title: Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes.
Volume: 9
Issue: 1
Pages: 3
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Publication
34381140 | J:331206
First Author: Mastrolia V
Year: 2021
Journal: Sci Rep
Title: Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity.
Volume: 11
Issue: 1
Pages: 16357
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12771146 | J:230354
First Author: Kruljac-Letunic A
Year: 2003
Journal: J Biol Chem
Title: The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1.
Volume: 278
Issue: 32
Pages: 29560-70
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21640103 | J:174314
First Author: Shen CJ
Year: 2011
Journal: Exp Cell Res
Title: Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.
Volume: 317
Issue: 13
Pages: 1860-71
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Publication
31330317 | J:293294
First Author: Gao C
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654.
Volume: 8
Issue: 4
Pages: 561-578
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22544749 | J:186506
First Author: Xu J
Year: 2012
Journal: J Biol Chem
Title: Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.
Volume: 287
Issue: 25
Pages: 20942-56
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32313025 | J:289605
First Author: de Pins B
Year: 2020
Journal: Sci Rep
Title: The non-receptor tyrosine kinase Pyk2 modulates acute locomotor effects of cocaine in D1 receptor-expressing neurons of the nucleus accumbens.
Volume: 10
Issue: 1
Pages: 6619
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Publication
20727793 | J:163910
First Author: Davidson D
Year: 2010
Journal: Immunity
Title: The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2.
Volume: 33
Issue: 2
Pages: 167-80
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Publication
28555636 | J:250330
 
First Author: Giralt A
Year: 2017
Journal: Nat Commun
Title: Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.
Volume: 8
Pages: 15592
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Publication
34943950 | J:317739
 
First Author: Gourley SL
Year: 2021
Journal: Cells
Title: Pyk2 Stabilizes Striatal Medium Spiny Neuron Structure and Striatal-Dependent Action.
Volume: 10
Issue: 12
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27226326 | J:240205
First Author: Alvau A
Year: 2016
Journal: Development
Title: The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm.
Volume: 143
Issue: 13
Pages: 2325-33
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30872746 | J:276607
First Author: Thomas KS
Year: 2019
Journal: Sci Rep
Title: Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair.
Volume: 9
Issue: 1
Pages: 4497
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25659487 | J:220743
First Author: Fukai K
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α.
Volume: 308
Issue: 8
Pages: H951-9
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9988732 | J:53091
First Author: Lakkakorpi PT
Year: 1999
Journal: J Biol Chem
Title: Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone.
Volume: 274
Issue: 8
Pages: 4900-7
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Publication
12578912 | J:81963
First Author: Wang Q
Year: 2003
Journal: J Cell Biol
Title: Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin.
Volume: 160
Issue: 4
Pages: 565-75
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16546139 | J:107563
First Author: Guignandon A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Cyclic strain promotes shuttling of PYK2/Hic-5 complex from focal contacts in osteoblast-like cells.
Volume: 343
Issue: 2
Pages: 407-14
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17684059 | J:128374
First Author: Faure C
Year: 2007
Journal: J Cell Sci
Title: Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons.
Volume: 120
Issue: Pt 17
Pages: 3034-44
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Publication
23401167 | J:195144
First Author: McGinnis LK
Year: 2013
Journal: Mol Reprod Dev
Title: Protein tyrosine kinase signaling in the mouse oocyte cortex during sperm-egg interactions and anaphase resumption.
Volume: 80
Issue: 4
Pages: 260-72
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25349423 | J:216771
First Author: Kinoshita Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stress.
Volume: 111
Issue: 45
Pages: 16130-5
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11238453 | J:67886
First Author: Ren XR
Year: 2001
Journal: J Cell Biol
Title: Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
Volume: 152
Issue: 5
Pages: 971-84
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26642240 | J:231935
First Author: Jabara HH
Year: 2016
Journal: Nat Genet
Title: A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Volume: 48
Issue: 1
Pages: 74-8
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22941736 | J:190159
First Author: Ray BJ
Year: 2012
Journal: J Leukoc Biol
Title: Regulation of osteoclast structure and function by FAK family kinases.
Volume: 92
Issue: 5
Pages: 1021-8
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23589331 | J:204493
First Author: Rhee I
Year: 2013
Journal: Mol Cell Biol
Title: Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/PTPN12.
Volume: 33
Issue: 12
Pages: 2458-69
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Publication
20805505 | J:164360
First Author: Beinke S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate.
Volume: 107
Issue: 37
Pages: 16234-9
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Publication
29803828 | J:269675
 
First Author: Giralt A
Year: 2018
Journal: Exp Neurol
Title: PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.
Volume: 307
Pages: 62-73
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Publication
30626696 | J:273600
First Author: Lee S
Year: 2019
Journal: J Neurosci
Title: Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss.
Volume: 39
Issue: 10
Pages: 1910-1929
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21372295 | J:191484
First Author: Katsume A
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system.
Volume: 31
Issue: 5
Pages: 1084-92
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18483407 | J:151384
First Author: Fisslthaler B
Year: 2008
Journal: Circ Res
Title: Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin.
Volume: 102
Issue: 12
Pages: 1520-8
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Publication
27796369 | J:259915
 
First Author: Chung IC
Year: 2016
Journal: Sci Rep
Title: Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis.
Volume: 6
Pages: 36214
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Publication
12674328 | J:180487
First Author: Gupta A
Year: 2003
Journal: J Bone Miner Res
Title: Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast.
Volume: 18
Issue: 4
Pages: 669-85
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14739300 | J:89495
First Author: Miyazaki T
Year: 2004
Journal: J Biol Chem
Title: Src kinase activity is essential for osteoclast function.
Volume: 279
Issue: 17
Pages: 17660-6
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19880522 | J:159965
First Author: Lim ST
Year: 2010
Journal: J Biol Chem
Title: Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.
Volume: 285
Issue: 3
Pages: 1743-53
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Publication
15786712 | J:180575
First Author: Watanabe N
Year: 2005
Journal: Mol Cell Biochem
Title: Leupaxin binds to PEST domain tyrosine phosphatase PEP.
Volume: 269
Issue: 1-2
Pages: 13-7
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16391003 | J:104401
First Author: Braren R
Year: 2006
Journal: J Cell Biol
Title: Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.
Volume: 172
Issue: 1
Pages: 151-62
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Publication
28385807 | J:243304
First Author: Soni D
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions.
Volume: 312
Issue: 6
Pages: L1003-L1017
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Publication
21187437 | J:168915
First Author: Kamen LA
Year: 2011
Journal: J Immunol
Title: Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection.
Volume: 186
Issue: 3
Pages: 1656-65
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Publication
25967238 | J:226138
First Author: Canobbio I
Year: 2015
Journal: Biochem J
Title: The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets.
Volume: 469
Issue: 2
Pages: 199-210
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Publication
22106345 | J:181791
First Author: Consonni A
Year: 2012
Journal: Blood
Title: Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.
Volume: 119
Issue: 3
Pages: 847-56
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25960397 | J:230524
First Author: Manganaro D
Year: 2015
Journal: Biochim Biophys Acta
Title: Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.
Volume: 1853
Issue: 8
Pages: 1879-88
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18542050 | J:137676
First Author: Yamamoto S
Year: 2008
Journal: Nat Med
Title: TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.
Volume: 14
Issue: 7
Pages: 738-47
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11274221 | J:79952
First Author: Andreev J
Year: 2001
Journal: J Biol Chem
Title: Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade.
Volume: 276
Issue: 23
Pages: 20130-5
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19416922 | J:248211
First Author: Marqués M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.
Volume: 106
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