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Search results 101 to 161 out of 161 for Ercc4

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Type Details Score
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Protein Domain
IPR006166 | ERCC4_domain
Type: Domain
Description: This entry represents a structural domain found in several DNA repair nucleases, such as Rad1, XPF and crossover junction endonucleases EME1 and Mus81 [, ]. The XPF/Rad1/Mus81-dependent nuclease family specifically cleaves branched structures generated during DNA repair, replication, and recombination, and is essential for maintaining genome stability. The nuclease domain architecture exhibits remarkable similarity to those of restriction endonucleases.
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Protein
Q56A04
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Protein
A0A1Y7VKY9
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
D3Z6X0
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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HT Experiment
E-MEXP-3930 | Transcription profiling by array of mouse Ercc1 knock out white adipose tissue
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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DO Term
DOID:0111093 | Fanconi anemia complementation group Q
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Protein
Q8BJW7
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Protein
Q9QZD4
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Publication
12679022 | -
First Author: Nishino T
Year: 2003
Journal: Structure
Title: X-ray and biochemical anatomy of an archaeal XPF/Rad1/Mus81 family nuclease: similarity between its endonuclease domain and restriction enzymes.
Volume: 11
Issue: 4
Pages: 445-57
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Publication
14527419 | -
First Author: Gaillard PH
Year: 2003
Journal: Mol Cell
Title: The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism.
Volume: 12
Issue: 3
Pages: 747-59
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Allele
Ercc4<em1Smoc> | MGI:7289536
Name: excision repair cross-complementing rodent repair deficiency, complementation group 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Ercc1<tm1Jhjh> | MGI:2183944
Name: excision repair cross-complementing rodent repair deficiency, complementation group 1; targeted mutation 1, Jan H J Hoeijmakers
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ercc4<tm1Fwa> | MGI:3028660
 
Name: excision repair cross-complementing rodent repair deficiency, complementation group 4; targeted mutation 1, Frederick W Alt
Allele Type: Targeted
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Allele
Fancm<em1Qsh> | MGI:6508081
Name: Fanconi anemia, complementation group M; endonuclease-mediated mutation 1, Qinghua Shi
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Ercc4/Ercc4
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110848 | xeroderma pigmentosum group F
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Protein
Q91ZJ0
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
F8WIN9
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: false
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Protein
F6VIY4
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: true
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Strain
MGI:6508100 | C57BL/6-Fancm<em1Qsh>
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
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Publication
29895858 | J:301639
First Author: Yin H
Year: 2019
Journal: Genet Med
Title: A homozygous FANCM frameshift pathogenic variant causes male infertility.
Volume: 21
Issue: 1
Pages: 62-70
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Genotype
Genotype
Symbol: Fancm/Fancm
Background: C57BL/6-Fancm
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:95412 | Ercc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Ercc1/Ercc1
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060590 | XFE progeroid syndrome
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Protein
Q8BGE5
Organism: Mus musculus/domesticus
Length: 2021  
Fragment?: false
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Protein
B2RX10
Organism: Mus musculus/domesticus
Length: 2021  
Fragment?: false
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Publication
16616109 | J:114912
First Author: Kang HM
Year: 2006
Journal: Cancer Genet Cytogenet
Title: DNA copy number alterations and expression of relevant genes in mouse thymic lymphomas induced by gamma-irradiation and N-methyl-N-nitrosourea.
Volume: 166
Issue: 1
Pages: 27-35
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Publication
17720715 | -
First Author: Tripsianes K
Year: 2007
Journal: Nucleic Acids Res
Title: Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization.
Volume: 35
Issue: 17
Pages: 5789-98
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Publication
16428464 | -
First Author: Guzder SN
Year: 2006
Journal: Mol Cell Biol
Title: Complex formation with damage recognition protein Rad14 is essential for Saccharomyces cerevisiae Rad1-Rad10 nuclease to perform its function in nucleotide excision repair in vivo.
Volume: 26
Issue: 3
Pages: 1135-41
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Protein Domain
IPR004579 | ERCC1/RAD10/SWI10
Type: Family
Description: This family includes Rad10 from budding yeasts, Swi10 from fission yeasts and ERCC-1 from animals andplants. All proteins in this family for which functions are known are components in a multiprotein endonuclease complex (usually made up of Rad1 and Rad10 homologues). This complex is used primarily for nucleotide excision repair but also for some aspects of recombination repair. In budding yeast, Rad10 works as a heterodimer with Rad1, and is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts or cross-linking agents. The complex forms an endonuclease which specifically degrades single-stranded DNA [].ERCC1 and XPF (xeroderma pigmentosum group F-complementing protein) are two structure-specific endonucleases of a class of seven containing an ERCC4 domain. Together they form an obligate complex that functions primarily in nucleotide excision repair (NER), a versatile pathway able to detect and remove a variety of DNA lesions induced by UV light and environmental carcinogens, and secondarily in DNA inter-strand cross-link repair and telomere maintenance. This domain in fact binds simultaneously to both XPF and single-stranded DNA; this ternary complex explains the important role of Ercc1 in targeting its catalytic XPF partner to the NER pre-incision complex [].
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Publication
- | J:2040
 
First Author: Deng ZM
Year: 1992
Journal: Cytogenet Cell Genet
Title: Segments of homology between human 16p and mouse chromosomes
Volume: 60
Pages: 170 (Abstr.)
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Publication
- | J:2927
First Author: Deng ZM
Year: 1992
Journal: Am J Hum Genet
Title: Segments of homology between human 16p13 and mouse chromosomes
Volume: 51
Issue: 4
Pages: A394 (Abstr.)
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Protein
H3BLF5
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
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Protein
E9PUM0
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
P07903
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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